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Breast Cancer Gene Lawsuit Argues Patents Invalid

bkuhn writes "The ACLU and the Public Patent Foundation have filed a lawsuit charging that patents on two human genes associated with breast and ovarian cancer are unconstitutional and invalid. The lawsuit (PDF) was filed on behalf of four scientific organizations representing more than 150,000 geneticists, pathologists, and laboratory professionals, as well as individual researchers, breast cancer and women's health groups, and individual women. Individuals with certain mutations along these two genes, known as BRCA1 and BRCA2, are at a significantly higher risk for developing hereditary breast and ovarian cancers."

19 of 294 comments (clear)

  1. I don't understand it. by FlyingSquidStudios · · Score: 4, Insightful

    Can someone explain to me why it's legal to patent genes in the first place? I thought patents were supposed to be for new and unique inventions.

    1. Re:I don't understand it. by ByOhTek · · Score: 4, Insightful

      It depends. If it is a gene you yourself designed, then it is a reasonable target for a patent (or, more likely, copyright). However, if it's a gene that occurs in nature, then it makes no more sense to patent that gene than a species of plant or animal, a rock you found walking into work in the morning, an ocean or a star (stellar, not media - actually, maybe both would make sense, thought the latter isn't natural).

      --
      Self proclaimed typo king, and inventor of the bear destroying coffee table (patent not pending).
    2. Re:I don't understand it. by fastest+fascist · · Score: 3, Insightful

      It depends. If it is a gene you yourself designed, then it is a reasonable target for a patent (or, more likely, copyright)

      Combine that idea with artificial, hereditary traits (designer kids etc.), and you have people who need permission from their friendly gene provider to reproduce. Bring on the GIAA lawsuits! Can't have people passing on copyrighted genetic material without authorization!

    3. Re:I don't understand it. by drinkypoo · · Score: 5, Insightful

      I don't remember electing Monsanto. Perhaps we should be asking our elected officials why Monsanto is permitted to continue to exist after their numerous offenses against not just the citizens of the USA, but actually humanity. Even Wikipedia seems to have forgotten the contaminated agent orange thing :P

      --
      "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
    4. Re:I don't understand it. by Organic+Brain+Damage · · Score: 5, Insightful

      "Your" elected official? Did you give "your" elected official more money than Monstanto gave "your" elected official? I didn't think so. So she is not really "your" elected official. Is she? Of course not.

    5. Re:I don't understand it. by nomadic · · Score: 4, Insightful

      I don't remember electing Monsanto. Perhaps we should be asking our elected officials why Monsanto is permitted to continue to exist after their numerous offenses against not just the citizens of the USA, but actually humanity. Even Wikipedia seems to have forgotten the contaminated agent orange thing :P

      Because the elected official then turns around, quotes the Bible, and promises to lower your taxes, and you vote for him or her.

      Anyone willing to limit corporate power is typically not elected, and not because Monsanto gave them money but because of tax-cut and deregulation fanaticism.

    6. Re:I don't understand it. by Duradin · · Score: 4, Insightful

      And this is where someone should point out that this would be an excellent reason to support government funded general scientific research.

      It's expensive, offers little return on investment monetarily but could greatly benefit the populace.

      Corps aren't shelling out the cash like they used to on research that wasn't going profit the shareholders within a couple of years.

    7. Re:I don't understand it. by osgeek · · Score: 5, Insightful

      Or your elected official promises to tax the rich and give you free health care, and you vote for him or her... then turns around and behaves in exactly the same corrupt way that you expected "the other team" to behave.

      Despite that identical outcome, you'll pat yourself on the back that you elected the team that says the right things with Olberman cheerleading you the whole way - while Sean Hannity and his players are gnashing their teeth and decrying the corruption that was okay when it was their guys.

      Montasano gets rich, the Politicians get rich, freedoms and quality of life issues suffer... but at least you get to hate those other guys.

      We are so fucked.

    8. Re:I don't understand it. by DrOct · · Score: 3, Insightful

      You know, I agree that there are probably some "rights" that aren't in the constitution, and that perhaps we don't have the "right" to, but the 9th amendment was put into the constitution for a reason:

      "The enumeration in the Constitution, of certain rights, shall not be construed to deny or disparage others retained by the people."

      Just because it's not specifically mentioned in the constitution doesn't mean we can't determine that we do in fact have a given right, and the founders certainly understood this, or they wouldn't have bothered to add that amendment.

    9. Re:I don't understand it. by Daniel+Dvorkin · · Score: 4, Insightful

      Without some protection of a genetic discovery, it makes no financial sense for a company to actually do the research and discover which genes control an aspect of a plant or animal's composition.

      Which is why most such research is done in university labs, not corporate. There has been for decades a perfectly good method of advancing scientific knowledge and turning it into usable technology: academic researchers, paid primarily with public funds, do the basic science, and that fraction of it which turns out to be commercializable gets taken up by corporate engineers. This balance started to fall apart with Bayh-Dole and Diamond v. Chakrabarty, and things have been getting worse ever since.

      --
      The correlation between ignorance of statistics and using "correlation is not causation" as an argument is close to 1.
    10. Re:I don't understand it. by drinkypoo · · Score: 5, Insightful

      Not my elected official, ours. While you are technically correct, attitudes like yours are self-defeating. We make them our official again by holding them accountable. We begin by making people aware of their culpability.

      The greatest trick the two-party system ever pulled was convincing voters that voting for "third" parties is a waste.

      --
      "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
    11. Re:I don't understand it. by TooMuchToDo · · Score: 5, Insightful

      As an IT professional/business owner who took up farming for the fun of it (124 acres to start, slowly buying up more land), farming is like owning a vineyard. You barely break even most years. So do I blame farmers who are trying to make their lives easier with Montasano products? No. I do blame Montasano for their practices, and because of that don't use their products myself.

    12. Re:I don't understand it. by Organic+Brain+Damage · · Score: 3, Insightful

      But voting for third parties is a waste. The third party candidates will be corrupted by campaign finance the minute they get elected. Unless you're talking about a third party that only runs in-human robots for office. The root problem with US democracy is campaign finance. Until we deal with campaign finance (aka legalized bribery of elected officials), all the rest is re-arranging deck chairs on the Titanic.

    13. Re:I don't understand it. by shaitand · · Score: 3, Insightful

      Lets not confuse this issue, this isn't about someone having a right its about taking one away.

      In the case of a gene the key to isolating it is just a sequence of DNA.

      It seems to me to be a pretty reasonable barrier that you can patent something you create but not something you discover.

      Mathematics (even math that is really complex and so mystifies people like algorithms, software, etc), chemical compounds, genetics. These are all things that were already there waiting for someone to stumble upon them. In other words, no matter how much time and effort you spent hunting for them they are a discovery and not an invention. There is nothing to stop you from utilizing your discovery (or sharing it for that matter but somehow I think companies would quickly find themselves hobbled without being able to read about the discoveries of others) to make inventions but the discovery itself should not be patentable.

      'This would bolster the advocates of national health care and create another (unwritten) constitutional right.'

      Every right is a natural right. As someone else already pointed out, government doesn't grant rights, it takes rights away. You are freest without any government at all. What is the purpose of society if it isn't to keep the people who form it safe, healthy, and secure? Sounds to me like you are a moderately successful individual who just doesn't want to pay his fair share of taxes and thinks his success entitles him to priority when hes sick.

    14. Re:I don't understand it. by Ikonoclasm · · Score: 4, Insightful

      They're patenting the sequence of amino acids. They say this is patentable because it excludes the introns and is after the post-transcription modifications. Patent law excludes naturally occurring phenomenon. The sequence is a naturally occurring phenomenon after the excision of the introns (don't ask about the language, we know it's goofy) and post-transcription modifications. It all occurs in nature and is thus unpatentable. However, the USPTO has decided that whatever happens after translation is patentable, which makes no sense from either a legal or scientific standpoint (which I happen to have experience in both).

      I was finishing my undergrad degree in Genetics and working for a patent agent writing claims and detailed descriptions for biotech patents when I discovered this loophole in patent law. I was livid as I knew first hand how toxic IP law is to scientific fields and had assumed, based on the explicit language of the law, that my chosen field would be only minimally affected.

      Basically, the prosecution is going to have to call on some good expert witnesses to explain every stage of how DNA is translated and transcribed into proteins. They'll need to put it in language a judge/jury can understand while also constantly pointing out what the law currently says you cannot patent a natural occurrence, which a gene sequenced from a living organism most certainly is.

      As others have mentioned, custom genes that are made in a lab and did not evolve naturally, those are perfectly reasonable to patent. Hell, even mixing and matching parts of different, naturally-occurring genes into a new gene is reasonably patentable. Patenting a naturally occurring sequence that exactly matches the gene as it has evolved to function in the cell is a gross violation of the law.

  2. Re:A sad day by Rary · · Score: 3, Insightful

    A sad day ... when parts of the human body can be copyrighted.

    They can't. Neither can they be patented (which, by the way, is completely different than copyright).

    What can be patented (but not copyrighted) is the process of performing diagnostic tests on a certain gene. To quote the article:

    "Myriad's patents give it exclusive right to perform diagnostic tests on the genes -- forcing other researchers to request permission from the company before they can take a look at BRCA1 and BRCA2, the ACLU said. The patents also give the company the rights to future mutations on the BRCA2 gene and the power to exclude others from providing genetic testing."

    This is not a good thing, but it does seem to fit within the scope of patents. This is more reason for patent reform.

    --

    "You cannot simultaneously prevent and prepare for war." -- Albert Einstein

  3. Why can someone patent something nature created? by olddotter · · Score: 3, Insightful

    I don't think you should be able to patent discoveries, only inventions. Can a law scholar speak as to how we got to this point?

    Where is Larry Lessig?
     

  4. Procedures by Thaelon · · Score: 3, Insightful

    It's almost certainly a patent of the procedure for isolating/identifying/testing with the genes.

    This is why procedures shouldn't be patentable.

    By definition, they're not inventions, but procedures.

    --

    Question everything

  5. Re:Bingo! by Darby · · Score: 5, Insightful

    Of course, you are welcome to disagree that this will work because neither regulation nor free markets have a pristine track record, hence the continued debate,

    Well, you're falling into a very serious error here by setting up a false dichotomy. "Regulation" and "Free Markets" aren't in any way opposites. Regulation is absolutely 100% necessary to the existence of anything even remotely approximating a free market. "Unregulated markets" and "Regulated markets" are actual opposites. Unregulated markets will never be anything like a free market. A properly regulated market can approximate a free market.
    An actual free market doesn't exist, has never existed, and can't possibly ever exist under any conceivable set of circumstances. It's an idealized hypothetical thing like the various frictionless planes, pulleys and such from high school physics.

    As long as people keep pretending that the debate is how you framed it, then there will never be reasonable discussion of the issue in the public domain. This is especially true since the people who benefit from un or poorly regulated markets are the ones framing the debate since they're the ones who own all of the media outlets etc.

    claiming that the "right" wants to be ruled by powerful corporations because of deregulation is like claiming that the "left" likes to kill babies because they want to allow the choice of abortion.

    The right consists primarily of the people who own the powerful corporations and the idiots who have been duped into believing that "the Right" means "Liberalism" (Small government, fiscal responsibility, individual liberty etc) when the right is an inherently elitist philosophy. Heck, the right is called the right because the representatives of the church and aristocrats sat on the right in the French assembly. The right *is* theocracy, feudalism, fascism etc. The representatives of the people sat on the left, hence the term "left", and hence the association of the left with "the people" against the "elites".

    Liberalism came later and was a rejection of *both* the left and the right. Left and right are both about using the power of the state to screw people for your benefit. Liberalism is the philosophy that nobody or group should be able to use the power of the state for the purpose of screwing individuals.

    It is the philosophy that America was explicitly founded on. People today don't even know that. They think "Liberalism" means "whatever somebody calling themselves a 'Liberal' says" which is obviously a worthless definition. There doesn't exist another word in the English language apart from "Liberalism" to describe America's founding philosophy, so it makes it tough to discuss since the Left have coopted and the Right have demonized the term. This is because both the right and the left *despise* Liberalism and always have.

    So, you, by pretending that the right stands for liberalism and the actual right doesn't even exist aren't helping to promote a more honest dialog, you're helping promote a redefinition which removes the terms necessary to accurately describe the political landscape.

    The powerful corporations are perfectly happy to have massively oppressive regulation of the people for their benefit. The recent bailout is a right wing initiative. *I*, the individual, was robbed at the behest of said corporations for their benefit.
    When "the rich" are robbed for the benefit of "the people", that's the left. When nobody is robbed by anybody by the government, that is a distinctly different position from either of the above.

    That very real and very critical distinction is entirely eliminated by the redefinitions you're going with.

    That is one of if not the most critical thing standing in the way of honest, non-partisan debate in this country. We don't even have to words to have such debate.