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Researcher Implants Laser-Activated Brain Cells

destinyland writes "A Stanford researcher has spliced light-sensitive algae genes into human brain cells to fire neurons when activated by a laser. Light is shined through an implanted fiber optic cable (blue light on, yellow light off), and the procedure can target very specific deep brain structures too fragile for most surgery. 'Once the researcher attaches the other end of the cable to a laser, he or she has absolute and flawless control over that group of neurons.' Science writer Quinn Norton cites it as a first attempt at 'building useful handles on the very things that make us ourselves.'"

98 comments

  1. Why brain cells.... by Darkness404 · · Score: 2, Informative

    This sounds an awful like binary.... Could this potentially be used to make bio-computers? Or at the very least Bio-Memory? Perhaps it has too many flaws to be useful, but the idea of using cells to store data is interesting to say the least.

    --
    Taxation is legalized theft, no more, no less.
    1. Re:Why brain cells.... by srk2040 · · Score: 0

      Finally, A freaking laser mounted IN the head.

  2. Let me guess by Anonymous Coward · · Score: 1, Funny

    Researcher Implants Laser-Activated Brain Cells

    ... in a shark?

    1. Re:Let me guess by Anonymous Coward · · Score: 0

      no, that would be Laser-Activating Brain Cells

    2. Re:Let me guess by spartacus_prime · · Score: 1

      no, that would be Frickin' Laser-Activating Brain Cells

      Fixed that for ya.

      --
      If you can read this, it means that I bothered to log in.
    3. Re:Let me guess by Anonymous Coward · · Score: 0

      Researcher Implants Laser-Activated Brain Cells

      ... in a shark?

      Well, it would help with this other problem...

  3. First Post! by Anonymous Coward · · Score: 0

    I hope they get really really good at these sorts of procedures, until they realize finally that the brian does not produce consciousness but rather, is an interface for it. When they do realize that, maybe they'll be a little humbled by those who have been saying as much for the last several thousand years and won't be so quick to discount such things in the future. Am I saying that standards of scientific usefulness don't matter? Of course not, and if your disagreement rests on such a mischaracterization it only reveals the waekness of your position. What I am saying is that scientifically useless != useless in every sense. It is only one way of knowing. Nothing more, nothing less.

    1. Re:First Post! by calmofthestorm · · Score: 3, Interesting

      We've been over this. God is sufficient but not necessary for consciousness. It's far too early to tell either way right now. Keep working on the Hard Problem:-)

      --
      93rd rule of Slashdot: No matter how obvious my sarcasm is, my comment will be taken seriously by someone.
    2. Re:First Post! by Bodhammer · · Score: 1

      until they realize finally that the brian does not produce consciousness but rather, is an interface for it. When they do realize that, maybe they'll be a little humbled by those who have been saying as much for the last several thousand years and won't be so quick to discount such things in the future.

      Brian: I'm not the Messiah! Will you please listen? I am not the Messiah, do you understand? Honestly!
      Girl: Only the true Messiah denies His divinity.
      Brian: What? Well, what sort of chance does that give me? All right! I am the Messiah!
      Followers: He is! He is the Messiah!
      Brian: Now, fuck off!
      [silence]
      Arthur: How shall we fuck off, O Lord?

      --
      "I say we take off, nuke the site from orbit. It's the only way to be sure."
    3. Re:First Post! by lxs · · Score: 2, Insightful

      God is sufficient but not necessary for consciousness.

      That's a completely meaningless statement, since both "God" and "consciousness" are vague concepts that nobody can define without some serious hand-waving.

    4. Re:First Post! by superwiz · · Score: 1

      You are confusing "nobody can" with "I cannot". Consciousness is not yet defined, but it will be. It's not a philosophical, but rather physical concept. All physical concepts, however complicated, are definable.

      --
      Any guest worker system is indistinguishable from indentured servitude.
    5. Re:First Post! by lxs · · Score: 1

      I knew I should have qualified it with an "at the moment" the second I hit submit, but your "it will be" isn't a given. We might find out how it works (and I hope we will), but perhaps we are fundamentally unable to.

      But we may construct an AI who can figure it out. (Who will subsequently be unable to explain it in a way out monkey brains can grasp it.)

    6. Re:First Post! by Anonymous Coward · · Score: 0

      Fucking idiot. All dogs go to heaven. Everyone knows that.

    7. Re:First Post! by Lumpy · · Score: 1

      But we may construct an AI who can figure it out. (Who will subsequently be unable to explain it in a way out monkey brains can grasp it.)

      and that is the point where the AI decides we are no longer the creator as we cant understand something basic, Decides we are lying to them and unworthy and starts a systematic extinction of the human race.

      See what you started? See? It's all because you had to open your mouth and correct one person...

      you Killed humanity sir.. I hope you can live with that.

      --
      Do not look at laser with remaining good eye.
    8. Re:First Post! by Intron · · Score: 1

      Can any system transcend itself? Can humans never understand consciousness? Isn't this the core of Gödel's Incompleteness Theorems? Aren't too many rhetorical questions annoying?

      --
      Intron: the portion of DNA which expresses nothing useful.
    9. Re:First Post! by Sinbios · · Score: 1

      There's nothing wrong that that statement though - proving one vague sufficiently proves the other, but to prove the other it is not necessary to prove the first.

      --
      Anyone can "stand up for what they believe", but it takes a very brave individual to change what they believe. - Loundry
    10. Re:First Post! by Anonymous Coward · · Score: 0

      No, But getting an answer to a rhetorical question, how about that, eh?

  4. Tinfoil glasses? by basementman · · Score: 2, Funny

    So I need to get tinfoil glasses now too so the government can't control my mind? How do you expect those of us that believe in conspiracy theories to see UFOs? Sounds shady.

    1. Re:Tinfoil glasses? by EmmDashNine · · Score: 1

      So I need to get tinfoil glasses now too so the government can't control my mind? How do you expect those of us that believe in conspiracy theories to see UFOs? Sounds shady.

      Obligatory Leia quote: "I don't know where you get your delusions, laser brain."

    2. Re:Tinfoil glasses? by superwiz · · Score: 1

      Somehow, this seems more reminiscent of a different SW character: Lobot.

      --
      Any guest worker system is indistinguishable from indentured servitude.
  5. No Sharks? by ArsonSmith · · Score: 0, Redundant

    If there implanting laser beams on heads, shouldn't Sharks be involved at least?

    --
    Paying taxes to buy civilization is like paying a hooker to buy love.
  6. If he can splice some photoelectric properties (generates small amount of electricity from lasers), we can finaly have a brain machine interface. But regardless this will make reading memory composition easier. Cyberpunk here we come!

    1. Re:Coool by Anonymous Coward · · Score: 0

      brain already has electricity.

    2. Re:Coool by The_church_of_funzie · · Score: 1

      Yep, and if we can add our own laser to electricty connectors we can finaly get write access, not just read.

  7. Noodly Appendages by Kratisto · · Score: 5, Funny

    Exactly. The further science comes, the closer scientists will be to proving the existence of the Flying Spaghetti Monster: The source of creation, consciousness, and morality. Finally, we can have world peace when the people of Earth are united in worship of the one, true God.

    --
    Conscience is the inner voice which warns us that someone may be looking.
    1. Re:Noodly Appendages by mcgrew · · Score: 1

      The arguments about "religion vs science" are silly at best. Religion/philosophy and science ask completely different questions, and neither can disprove any claim of the other. To hunt for scientific proof of God's existance or nonexistance is absurd.

      The difference between God and the Flying Spagetti Monster is that nobody has ever experienced the flying spagetti monster. See Death

  8. Laser Heads by bughunter · · Score: 1

    Put me down for a laser stimulation implant of the nucleus accumbens .

    Speaking of "stimulated emissions," I'll never leave the house!

    --
    I can see the fnords!
    1. Re:Laser Heads by oneirophrenos · · Score: 4, Funny

      Like with all drugs that activate the nucleus accumbens, you'd develop tolerance. Soon even the largest laser doses wouldn't suffice, and you'd become a laser addict, roaming the streets, rummaging through trash containers, trying to find old CD drives to get your laser fix. Is that really the kind of life you want for yourself?

    2. Re:Laser Heads by bughunter · · Score: 2, Funny

      Yea, coherent light would become a controlled substance. Wicked Lasers would be contraband. Laser junkies would be hanging around the NIF, begging for spare photons. It wouldn't be pretty.

      So, thanks for the foresight. I'll have them run a copper wire alongside my fiber, just in case.

      --
      I can see the fnords!
    3. Re:Laser Heads by Yuuki+Dasu · · Score: 2, Informative

      I'll have them run a copper wire alongside my fiber, just in case.

      Congratulations, you've invented the droud. Larry Niven would be proud.

    4. Re:Laser Heads by BluFusion · · Score: 1

      Wicked Lasers should be contraband anyway. They sell overpriced, under-spec pieces of junk.

    5. Re:Laser Heads by commodoresloat · · Score: 1

      Like with all drugs that activate the nucleus accumbens, you'd develop tolerance. Soon even the largest laser doses wouldn't suffice, and you'd become a laser addict, roaming the streets, rummaging through trash containers, trying to find old CD drives to get your laser fix. Is that really the kind of life you want for yourself?

      Yes!

    6. Re:Laser Heads by DigiShaman · · Score: 1

      Could be worse. You could OD on a laser powerful enough to vaporize a hole your head!

      --
      Life is not for the lazy.
    7. Re:Laser Heads by mcgrew · · Score: 1

      There's an Isaac Asimov story with this as the theme. The problem (in the story) is, you have to have it plugged into a 110v AC outlet. It's a detective story, an addict is murdered when someone makes his electric cord so short he can't reach the kitchen or bathroom, so he starves to death as he can't bear to unplug it.

      I can't remember the story's name, but iirc the book it was in was titled Supermen.

    8. Re:Laser Heads by Anonymous Coward · · Score: 0

      Sounds more like Larry Nivens' Death By Ecstasy.

    9. Re:Laser Heads by Anonymous Coward · · Score: 0

      I happen to be a neuroscience grad student and recently attended a guest lecture by Prof. Deisseroth. First off, the whole point of the technique is that this a way to DIRECTLY stimulate neurons, i.e., they cannot help but fire an action potential when the light comes on. Dependence and tolerance issues are not relevant, and you get much greater target specificity--just the neurons you want, and only when you want.

      In my opinion, the WSJ had a better article on the topic: http://online.wsj.com/article/SB124571858121939515.html

      It's really a great idea, and many of us left feeling stupid for not coming up with it ourselves.

    10. Re:Laser Heads by bughunter · · Score: 1

      Precisely. Asimov's mystery (and Niven's "Tasp") were the inspiration for my OP. You win a cookie! (_)

      --
      I can see the fnords!
  9. Zombie armies by syousef · · Score: 2, Funny

    I have this mental image of a bunch of soldiers with sets of remotely controlled optical fibers hanging out of their head. For some reason in this image they're all kind of grey like something out of Edward Scissorhands or perhaps The Matrix, or maybe The Borg from Startrek....and the best bit is that the guy controlling them is doing it with an r/c aircraft radio. "Crush, kill, destroy, my pets!". Wait, I think someone has implanted MY brain with Hollywood crap. They did it the old fashioned way though - tv brainwashing.

    --
    These posts express my own personal views, not those of my employer
    1. Re:Zombie armies by calmofthestorm · · Score: 1

      It'd probably be cheaper to just build Killbots, and people would complain less too. Not to mention better armored.

      --
      93rd rule of Slashdot: No matter how obvious my sarcasm is, my comment will be taken seriously by someone.
    2. Re:Zombie armies by bughunter · · Score: 1

      and the best bit is that the guy controlling them is doing it with an r/c aircraft radio.

      And the twist at the end is that the guy with the r/c controller is really a robot!

      --
      I can see the fnords!
    3. Re:Zombie armies by KTheorem · · Score: 1

      And if they die you can always build more killbots.

    4. Re:Zombie armies by supernova_hq · · Score: 1

      Bah, you missed that last 5 minutes where you find out the guy is real and the R/C controller is actually controlling HIM!

    5. Re:Zombie armies by zmollusc · · Score: 1

      And maybe they could run Lotus Notes?

      --
      They whose government reduces their essential liberties for temporary security, receive neither liberty nor security.
    6. Re:Zombie armies by Lumpy · · Score: 1

      ""Crush, kill, destroy, my pets!". "

      If it was made by microsoft, right after that command they all would start stomping the life out of your pets....

      What would you do without mister fluffles?

      --
      Do not look at laser with remaining good eye.
    7. Re:Zombie armies by YourExperiment · · Score: 1

      Sounds a little like a Divine Assassin to me.

  10. Slashdot stories featuring lasers by sakdoctor · · Score: 1

    Instantly flooded with posts beating that dead horse. (Dead shark?)

  11. Lock and Load by HangingChad · · Score: 1

    Lock phasers on the pleasure centers.

    Stand by to fire.

    --
    That's our life, the big wheel of shit. - The Fat Man, Blue Tango Salvage
  12. So.... by camperdave · · Score: 1

    So, how do they get the laser beam through the person's thick skull to shine on these light sensitive cells?

    --
    When our name is on the back of your car, we're behind you all the way!
    1. Re:So.... by Anonymous Coward · · Score: 1, Informative

      This is surgery, it's a way to manipulate cells that you can't reach.
      RTF Summary.

    2. Re:So.... by The+Archon+V2.0 · · Score: 2, Funny

      So, how do they get the laser beam through the person's thick skull to shine on these light sensitive cells?

      AWESOME! My major in trepanation will finally come in handy! Just let me warm up my drill and I'll be coasting through this recession on the cutting edge of science, baby!

    3. Re:So.... by zarzu · · Score: 3, Interesting

      they need to open up the brain to insert the virus and it seems they install a 50 micrometer fiber optic cable that points to the specific cells right after that. and my best guess is that you have a cable coming out of your head which you then connect to the laser. the whole thing sounds pretty amazing with the whole algae and archaeon genes, very cool.

    4. Re:So.... by X0563511 · · Score: 1

      This is the Matrix on a small scale.

      Imagine that big plug really being a bundle of tiny fiber optic jacks...

      --
      For large sets, this will be our guide even unto death, for the LORD will work for each type of data it is applied to...
    5. Re:So.... by Metasquares · · Score: 1

      ...And a working knowledge of how high-level cognitive phenomena emerge from the firings of these neurons...

    6. Re:So.... by SlashWombat · · Score: 1

      Imagine that big plug really being a bundle of tiny fiber optic jacks...

      Gibson called them MicroSofts ... Rather apt I thought!

    7. Re:So.... by davester666 · · Score: 1

      So, you get one of these cables implanted, then murder somebody. You can then claim that somebody else made you do it!

      --
      Sleep your way to a whiter smile...date a dentist!
  13. Great, now commercialize it.. by QuantumG · · Score: 2, Interesting

    Things you need to do with your DNI:

    1. Invoke mental imagery, preferably without interfering with normal vision.
    2. Infer mental imagery manipulation.. for example, when you hear the question "what letter do you get by turning a Z on its side?" results in a common specific quale of visual intelligence.
    3. Test and improve the rate and bandwidth.

    With such an interface you can do human computer interaction in ways that are completely unavailable to current input devices. Imagine having a 3d modeling tool where you can just think about the object you want, or how it differs from the object you're seeing. Imagine, if you can, receiving data at a higher bandwidth than video.

    --
    How we know is more important than what we know.
    1. Re:Great, now commercialize it.. by bertoelcon · · Score: 1

      Really, the last place i want a virus is in my brain from hooking it to a computer, however if it was just an input device and could not have any feedback it might be ok.

      --
      Anything can be found funny, from a certain point of view.
    2. Re:Great, now commercialize it.. by gknoy · · Score: 1

      Even if a neural interface were only able to replace my mouse and keyboard (or multiple ones), I'd be happy. No need to worry about ergonomic "layout"s, no repetetive stresses. I'd love to see that, even if it's a ways off still.

    3. Re:Great, now commercialize it.. by QuantumG · · Score: 1

      the last place i want a virus is in my brain from hooking it to a computer

      Too late.

      --
      How we know is more important than what we know.
  14. Bill Gates Borg by travisb828 · · Score: 1

    The Bill Gates Borg icon should be used with this story.

    But seriously this is cool, but is an AI running on a nero-optic processor alive?

  15. Some pics by aztektum · · Score: 4, Funny

    Here's a pic of the subject hooked up to the machine.

    --
    :: aztek ::
    No sig for you!!
  16. Make us ourselves by gmuslera · · Score: 1

    Is not the same a bunch of bricks than a home, even if you arrange them as in a house.

  17. Here comes our direct Neural Link by physburn · · Score: 3, Interesting
    Sci-fi has been having human "jacking in" to computer systems, via direct connection to the brain for a while. This technology ought to make that possible, Just how to make the brain cells actually connect themselves in some useful way to the rest of the brain, seems tricky though, and i hope these gene splice brain cells are safe against cancer etc.

    ---

    Futurology Feed @ Feed Distiller

  18. Anonymous Coward by Anonymous Coward · · Score: 0

    We knew that "pig and elephant DNA just don't splice", but human brain and algae DNA does? Was there a five-assed monkey working the laser?

  19. aren't there already by bugs2squash · · Score: 1

    wasps that can do this to ants ?

    --
    Nullius in verba
  20. Now we know how the mind control lasers work. by Ungrounded+Lightning · · Score: 2, Funny

    And why the operators are called "illuminati". B-)

    --
    Bantam Dominique roosters crow a four-note song. Once you've heard it as "Happy BIRTHday" you can't NOT hear it that way
  21. By Neruos by Anonymous Coward · · Score: 0

    Cocky Rubish..

    No respected science publication would every say "absolute and flawless control" over a area of the body that humans understand very little about. Getting a neruon to fire in a petridish in a controlled enviroment is one thing, getting it to work in the field is another. Call me after you have 5-10 years of human trails under your belt.

  22. The logical outcome by Anonymous Coward · · Score: 0

    Just wait until everybody has algae embedded in their brains. I for one welcome our new shark overlords.

  23. So lets do this to... by Anonymous Coward · · Score: 0

    So lets do this to a couple sharks, that way the Freakin Laser Beams can activate their KILL sense too!

  24. Frikin laser beams inside of their heads by Anonymous Coward · · Score: 0

    Great, now I can have sharks with frikin laser beams inside of their heads!

  25. Execute Order 66 by Neanderthal+Ninny · · Score: 0

    I wonder if they can turn on embedded programmed neurons so that you that you fire a laser to that person to tell them to do something, just like Star Wars: Episode III - Revenge of the Sith where Palpatine give the command "Execute Order 66".

  26. this is a great advance for science by circletimessquare · · Score: 0

    it brings us closer to realizing this great future:

    http://images.google.com/images?q=seven%20of%20nine

    but hopefully not this future:

    http://memory-alpha.org/en/wiki/Borg_Queen

    --
    intellectual property law is philosophically incoherent. it is your moral duty to ignore it or sabotage it
  27. the matrix anyone? by martas · · Score: 1

    now all we need is very advanced AI that is too retarded to build nucular power plants.

  28. This isn't good... by Kid+Zero · · Score: 3, Funny

    everyone will become light headed.

    1. Re:This isn't good... by mcgrew · · Score: 1

      Hey, didn't they just run a story about pot a few days ago?

  29. Brain activated laser? by SirAdelaide · · Score: 1

    Now we just need brain activated laser cells.

    --
    I'm a fruit pirate. I bought a watermelon once, and spat the seeds in the back yard. They grew into another watermelon,
    1. Re:Brain activated laser? by karlwilson · · Score: 1

      Scientists are currently in the process of splicing algae DNA with shark DNA.

  30. Sharks with What . . . by wooferhound · · Score: 1

    I am visualizing sharks with frigging lasers in my head . . .

    --
    We are Dead Stars looking back Up at the Sky
  31. I would just like to add... by kms_one · · Score: 1

    MUAHAHAHAHAHAHA!

  32. H+ mag slashvertisements by destinyland by dave1g · · Score: 1

    destinyland only posts stories from H+ magazine... they are neat but feels like its just an advertising extension ala Roland (RIP)

  33. Lights On, Or Lights Off?..... by IHC+Navistar · · Score: 1

    I guess that this particular neurologist likes to do it with the lights on.....

    ---

    Welders do it in all positions.

    --
    Knowing Google's lust for data collection, the Soviet Union is still alive and well inside the psyche of Sergey Brin....
  34. Spinal damage by quantumphaze · · Score: 4, Interesting

    I wonder if this can be applied to other purposes like bypassing damaged sections of a paraplegics spinal cord.

    We would need to develop a neuron to laser device at the other end first, but the possibilities of making people walk again are worth investment.

  35. "The Terminal Man" (and I don't mean UNIX) by wisebabo · · Score: 1

    Before Michael Crichton got in bed with the oil industry with "State of Fear" (with rain forest venom dart shooting environmentalists driving Priuses) he wrote some really good science fiction (like "The Andromeda Strain"). In a previous book "The Terminal Man" he wrote about a man who had electrical impulses providing him with biofeedback (which he abuses). Substitute lasers and Voila!
    It was later made into a movie. Anybody see it?

  36. "The Terminal Man" (and other stories) by wisebabo · · Score: 1

    Before Michael Crichton got in bed with the oil industry with "State of Fear" (with rain forest venom dart shooting environmentalists driving Priuses) he wrote some really good science fiction (like "The Andromeda Strain"). In a previous book "The Terminal Man" he wrote about a man who had electrical impulses providing him with biofeedback (which he abuses). Substitute lasers and Voila!
    It was later made into a movie. Anybody see it?
    Also, there was an Arthur C. Clarke science fiction story where electrodes were used to "train" Orcas from eating dolphins.
    Finally, in real life, there was a (I think) DARPA funded project where they managed to remotely control a large beetle into flying whichever direction they chose. A tiny radio triggered electrodes which were connected to the appropriate neurons and thus they could make it go left, right, etc. Gives new meaning to the phrase "bug on the wall".
    I'm wondering when they'll be able to "improve" this technology so as to make people into remote controlled "zombies"!

  37. Do not connect laser to remaining good lobe... by N+Monkey · · Score: 1

    Could be worse. You could OD on a laser powerful enough to vaporize a hole your head!

    A friend of mine used to work with very high powered C02 lasers. For demonstration purposes they used to destroy bricks. Sounds like just the ticket!

  38. Better in reverse by merlinokos · · Score: 1

    Researcher Implants Brain Cell-Activated Lasers!
    Fixed that for you.

  39. Laser-activated Brain Cells? by Sapphon · · Score: 1

    The reverse of that would be so much cooler.

    --
    Antiquis temporibus, nati tibi similes in rupibus ventosissimis exponebantur ad necem.
  40. Slashdot's been going downhill... by Eli+Gottlieb · · Score: 1

    Researchers have learned how to make light-activated brain cells that can affect deep-brain structures and help us in "building useful handles on the very things that make us ourselves". And yet, I'm the only person who tagged this article "Dollhouse". Come on, people! Star Trek references are old; you have to move with the times if you want to keep your geek license!

    Light-activated brain writing -> Dollhouse. You should know this stuff.

    1. Re:Slashdot's been going downhill... by Anonymous Coward · · Score: 0

      ... and as a real geek, you should know that keeping up with the times is reminiscing about stuff that was good x number of years ago. Neither Star Trek nor Star Wars was as popular to the geek crowd when it was still in its infancy. The Dollhouse is too new to be a geek classic.

  41. Illuminati, anyone? by Zephyn · · Score: 1

    The OMCLs (Orbital Mind Control Lasers) are on the board. Whatever you do, don't let the Bermudans get a hold of them.

  42. Good stuff by hesaigo999ca · · Score: 1

    Next...we will be able to use this to counter the deficiency that makes Parkinson's disease so horrible.

  43. Philip K. Dick would wonder.... by Ktistec+Machine · · Score: 1

    ...what does the PINK light that Valis shines on your brain do to you?

  44. so... by JustNiz · · Score: 1

    Blue = become alliance, Yellow = become horde

  45. why rhetorical by Kargoroth · · Score: 1

    and i alway thought the theorem meant that you need some sort of observable reality that to build your consistent systen on.