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Human Sperm Produced In the Laboratory

duh P3rf3ss3r writes "The BBC is carrying a report from a team of researchers at Newcastle University who claim to have developed a the first 'artificial' human sperm from stem cells. The research, reported in the journal Stem Cells and Development, involved selecting meristematic germ cells from a human embryonic stem cell culture and inducing meiosis, thus producing a haploid gamete. The authors claim that the resulting sperm are fully formed, mature, human sperm cells but the announcement has been greeted with mixed reaction from colleagues who claim the procedure is ethically questionable and that the gametes produced are of inferior levels of maturation."

4 of 368 comments (clear)

  1. Blood==Stem Cells==Babies????? by MarkvW · · Score: 4, Interesting

    If a woman gets your blood, then she can bear your children? Wow! This will be a great argument for deadbeat dads! Now they can truthfully say "I never had sexual relations with that woman."

    Black markets for the blood of rich men . . .
    Personal IP rights in your personal blood composition . . .

    Wow, the world got more interesting on 7/08/2009!!!!

  2. Re:So what? by ElKry · · Score: 5, Interesting

    And, on a chilling (for me) twist, if they took stem cells from a woman, they could generate some sperm for her, thereby allowing her to impregnate herself .

  3. Re:One implication by thesandtiger · · Score: 4, Interesting

    Infertile heterosexual couples can't currently conceive children. This could grant that ability. That's huge. So how is the sexual orientation of the couple relevant?

    If the OP had said "This will allow people who couldn't have conceived the ability to have children, this opens up a can of worms" then sure - but he (and you) specifically mention the sexual orientation of the couples as being relevant. I'm just trying to understand why.

    Is it because gay people would be able to have children that share the dna from 2 same-sex parents? Is it because gay people having kids is an ethical concern? Is it squeamishness about gay folks being able to have children?

    --
    Since I can't tell them apart, I treat all ACs as the same person.
  4. Re:So what? by interkin3tic · · Score: 5, Interesting

    Sperm doesn't have pairs of chromesomes, it has only one. But you're right, if you make sperm from female stem cells it could only have an X chromesome, never a Y chromesome, so you'd only get female offspring.

    The only inherent loss of genetic diversity would be the Y chromesome, which doesn't have much genetic information on it anyway. The wiki page on the Y chromesome points out that "the human Y chromosome itself contains only 78 working genes, compared to close to 1500 working genes on the X chromosome" and none of the 78 are "vital." For women anyway for obvious reasons.

    As long as the female that the sperm are derived from isn't closely related to the female that produces the egg, it wouldn't seem like there would be diversity loss.