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Nicotine Improves Brain Function In Schizophrenics

An anonymous reader suggests a Cosmos Magazine note that nicotine has been shown to enhance attention and memory in schizophrenics. Research is now aimed at developing new treatments that could relieve symptoms and prevent smoking-related deaths. "A strong link between schizophrenia and smoking — with over three times as many schizophrenics smoking (70 to 90%) as the population at large — prompted scientists to investigate the link. Researchers led by Ruth Barr, a psychiatrist at Queen's University in Belfast, Northern Ireland, set out to find if the nicotine in cigarettes was helping patients to overcome their difficulties with cognitive function, such as planning and memory in social and work settings."

6 of 297 comments (clear)

  1. Re:Finally, a reason. by Zantac69 · · Score: 3, Interesting

    Now they need to do a study on those of us who run on caffeine...

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    1331461 is only semiprime *sigh* Alas - I am just short of 1337.
  2. Interesting by Dustie · · Score: 5, Interesting

    As I suffer from schizophrenia myself I know how bad your memory can get because of it. Maybe there is a connection between I stopped smoking and I (finally) got a diagnose on what was wrong with me. Perhaps it made the symptoms clearer?

    I sure hope it is correct and doesn't get debunked.

    1. Re:Interesting by Dustie · · Score: 3, Interesting

      Sadly Abilify makes me seriously ill even with half the dose of the smallest pill and Seroquel both made me tired like a walking zombie and also made me put on a lot of weight. As far as I know I have tried all of the "new anti psychotics". Only one that wasn't too bad was Zeldox. Unfortunately it does not look like science is going to understand schizophrenia (or the brain for that matter) anytime soon especially the "negative symptoms".

      Negative symptoms - Wikipedia:

      ...loss or absence of normal traits or abilities, and include features such as flat or blunted affect and emotion, poverty of speech (alogia), inability to experience pleasure (anhedonia), lack of desire to form relationships (asociality), and lack of motivation (avolition).

  3. Re:Typical by BubbaDave · · Score: 5, Interesting

    We have genetic engineers- it's about time to crossbreed tobacco with coffee so coffee has caffeine and nicotine.

    Dave

  4. FWIW by mindbrane · · Score: 3, Interesting
    Schizophrenia isn't very well defined and, to further complicate things, there are diagnoses that couple schizophrenia with other disorders that, in turn, aren't well defined. Two current, prevalent theories, not necessarily at odds, suggest on one hand that schizophrenia is tied directly into the dopamine system, and, OTOH, that schizophrenia is a disorder arising from the brain's architecture. The first theory usually involves medications that dampen the dopamine system but that have, literally, potentially killer, side effects. The idea that schizophrenia is tied to the brain's architecture is broad and incorporates ideas that there are genetic, congenial causes for schizophrenia that can be exacerbated by environmental factors, such as physical, or, emotional insult or forms of neglect. Concurrent with the second view is that the small, inter neurons that connect long range disparate neural pathways don't function up to par in schizophrenics. Smoking cigarettes is prevalent among schizophrenics but given the lack of consensus as to what constitutes schizophrenia it's unlikely that a link between the effects of nicotine and schizophrenic symptoms is rigorous or robust. Nicotine and caffeine both seem to be disproportionatley favoured by certain types of uni students. I doubt there's any significant representation of schizophrenia among said population of students.

    The positive symptoms of schizophrenia are those the public is most likely to bring to mind when envisioning schizophrenics, these include auditory hallucinations and paranoid behaviour. It's these symptoms that seem to be most amenable to treatment with drugs that act on the dopamine system. The second set of the disease's symptoms are termed negative symptoms and include social isolation and degrees of depression. These secondary symptoms currently have few effective treatments. My best guess would be that nicotine and smoking, (the ritual and anachronistic, Freudian, oral pleasure) treat the secondary symptoms.

    FWIW I'm a diagnosed schizophrenic with a uni education and a plus 160 IQ. I've been diagnosed as schizophrenic, schizo-affective, and, possibly not schizophrenic at all; but my favourite diagnosis came from a neuropsychiatrist, who, upon learning that I had begun studies of epistemology at age 17, said: "People who study epistemology... (long pause)... I don't know... (head shaking)... I just don't know." My case seems to be the more interesting because I recognized my symptoms and sought medical attention, and, while suffering the full range of symptoms, was able to deal with them as symptoms of a disease and not as in any way defining who I am or considering them as causes of action. John Nash, he of "A Beautiful Mind" escaped the symptoms of his schizophrenia when he learned not to argue with his voices. The most debilitating aspect of schizophrenia is that people seem not to understand that it's a brain based disease and that the mind, as put by a neuroscientist, is just the brain doing it's job. More high functioning schizophrenics are able to get on with their lives because schizophrenia is now known to be a a disease no different than any other and the symptoms can be detected, marked, treated, minimized, and, over time, all but disregarded in day to day life.

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    ideopath @ play
  5. Nicotine benefits without the harmful smoke by ami.one · · Score: 3, Interesting

    Electronic Cigarettes (more accurately -Personal Vaporizer or PV) simply vaporize a nicotine solution to avoid the harmful effects of smoke and its 8000 chemicals.

    I was on a pack a day for 15 years and in a month of starting 'vaping' i have gone to zero analog cigarettes without missing my nic kick.

    Checkout Wikipedia for basic info or ecig-forum for detailed info.

    These look like normal cigarettes, have rechargeable batteries with convenient cartridges or refilling BUT it does takes a week or two to get everything right,so be careful of which model etc you choose. Ask me for advise if in doubt.

    Incidentally, FDA is trying to ban them for some of the most stupid reasons

    AND - I am not associated with any seller etc. so its not a plug. Just trying to help !