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Alzheimer's Disease Possibly Linked To Sleep Deprivation

sonnejw0 writes "NewScientist is reporting a link between sleep deprivation and Alzheimer's Disease via an increased amyloid-beta plaque load thought responsible for a large part of the symptoms of the disease, in mice. Medication to abrogate insomnia reduced the plaque load. Also discussed is a recently discovered sleep cycle of amyloid-beta deposition in the brain, in which levels decrease while asleep. 'Holtzman also tried sending the mice to sleep with a drug that is being trialled for insomnia, called Almorexant. This reduced the amount of plaque-forming protein. He suggests that sleeping for longer could limit the formation of plaques, and perhaps block it altogether.'"

6 of 164 comments (clear)

  1. "You can sleep when you're demented" by Anonymous Coward · · Score: 1, Funny

    "You can sleep when you're demented"

  2. Got an idea if you don't have time for sleep by vehicle+tracking · · Score: 2, Funny

    Why don't we all just start taking Holtzman?

  3. I stayed up all night... by nycguy · · Score: 4, Funny

    ...trying to think of a clever comment, but now I forgot it!

  4. As a graduate student... by magsol · · Score: 4, Funny

    ...I am SO screwed. I think.

    --
    "I'd just like to emphasise that taking a million years isn't a metaphor here..." -Rich Bradshaw
  5. But... But... But... by Greyfox · · Score: 2, Funny

    A while back they said that caffeine could prevent or slow the disease. Since then I've been drinking 12 cups of coffee a day and sleep on average 30 minutes a night! And now this? Bastards!

    --

    I'm trying to teach myself to set people on fire with my mind... Is it hot in here?

  6. Re:Why do we sleep? by fuzzyfuzzyfungus · · Score: 2, Funny

    The presence of large numbers of old people makes hunting for food way easier. If you aren't picky.