Slashdot Mirror


Engineered Bacteria Glows To Reveal Land Mines

MikeChino writes "Sifting through minefields to remove hidden threats is a dangerous, tedious, and expensive process. Scientists at the University of Edinburgh recently announced that they have engineered a strain of bacteria that glows green in the presence of explosives, making mine detection a snap. The new strain of bacteria can be sprayed onto local affected areas or air-dropped over entire fields of mines. Within a few hours the bacteria strain begins to glow wherever traces of explosive chemicals are present."

51 of 248 comments (clear)

  1. Pitch by ExE122 · · Score: 4, Informative

    ...making mine detection a snap

    I dunno, sounds like a sales pitch to me... you should have either written it in all caps Billy Mays style or said, "Made in Scotland... you know the Scottish make good stuff"

    Reguardless, the article has already been /.ed so here are some other sources: Discover, Treehugger, and DNA

    --
    Capitalism: When it uses the carrot, it's called democracy. When it uses the stick, it's called fascism.
    1. Re:Pitch by Ziwcam · · Score: 2, Interesting

      Simple countermeasure: After placing mines, spray field with explosive residue. Now what?

    2. Re:Pitch by OverlordQ · · Score: 4, Informative

      Your first two links are the same, might have been meant to direct here instead.

      --
      Your hair look like poop, Bob! - Wanker.
    3. Re:Pitch by MyLongNickName · · Score: 4, Insightful

      This would likely be used for already existing minefields. Afghanistan is the most mined country in the world, and cleanup efforts are very tedious. I think that is the market for this product.

      --
      See my journal for slashdot ID's by year. Mine created in 2005. http://slashdot.org/journal/289875/slashdot-ids-by-year
    4. Re:Pitch by Ziwcam · · Score: 2, Interesting

      Hey now, I was simply pointing out an obvious shortcoming to the potential usefulness of this in an area where insurgents still want to keep it mined. When used to clean up abandoned minefields, I think this product has the potential to save tons of lives (and limbs). No need for you to wish me into the middle of a minefield simply because I pointed out a potential countermeasure to the product.

    5. Re:Pitch by tophermeyer · · Score: 5, Insightful

      Also useful in Southeast Asian countries, where cleanup is all but ignored by local government, and the practical cost of disposal is roughly 1 human appendage per mine.

    6. Re:Pitch by Maximum+Prophet · · Score: 4, Interesting

      Or, after one or more mines explode, does the entire field become tainted with explosive residue?

      --
      All ideas^H^H^H^H^Hprocesses in this post are Patent Pending. (as well as the process of patenting all postings)
    7. Re:Pitch by Chapter80 · · Score: 4, Funny

      Do they have a bacteria that can help me with FreeCell? I was already pretty good at Minesweeper.

    8. Re:Pitch by reverseengineer · · Score: 5, Informative

      It looks like the University of Edinburgh entered this project in the International Genetically Engineered Machine competition, so they have a project page with a lot of information. From what I gather, it would appear that the system is based on a system of enzymes that break down soil nitrites which have been linked to Green Fluorescent Protein. Nitrites are a natural byproduct of the breakdown of nitro-based explosives like TNT and PETN. Of course, soil nitrites from non-leaking landmine sources, like chemical fertilizers would also trigger fluorescence, so the team engineered a non-natural gene promoter protein. The genes to produce the fluorescent complex only get transcribed and translated into protein if the promoter is active. The activator for that promoter is a molecule of TNT, so the bacteria will only glow if TNT is present.

      I'd also encourage people to take a look at the other iGEM projects. Lots of interesting reading.

      --
      "FDA staff reviewers expressed concern about the number of patients who were left out of the study because they died."
    9. Re:Pitch by Vainglorious+Coward · · Score: 5, Informative

      Afghanistan is the most mined country

      Afghanistan comes in 4th according to this source. I was a little surprised that Egypt tops that list.

      --
      My next sig will be ready soon, but subscribers can beat the rush
    10. Re:Pitch by somersault · · Score: 2, Insightful

      As long as it doesn't result in any false negatives, I think it sounds like a great product for speeding up sweeping. Even if half of a 'field does end up alight, at least they can ignore the dark portions and concentrate on the lit areas.

      In a sparsely mined area it could save weeks, months or years of painstaking work - or a few limbs in the case where currently nobody is bothering to sweep the area clean at all.

      The next step is for the bacteria to auto dissolve the explosives, kind of like that blue stuff in Predator, heh. I just hope these little guys don't have the potential to cause more problems than they solve!

      --
      which is totally what she said
    11. Re:Pitch by PRMan · · Score: 4, Interesting

      I had a co-worker from Afghanistan in the past (nice guy). He said that his uncle would do it is to buy a field with land mines on it for cheap and then just let a herd of goats graze the property. If a goat exploded, that one was dinner.

      Simple. Cheap. Effective.

      --
      Peter predicted that you would "deliberately forget" creation 2000 years ago...
    12. Re:Pitch by amicusNYCL · · Score: 4, Funny

      Well sure, but who has to go recover the goat? For that you need goat-recovering dogs.

      --
      "Our two-party system is like a bowl of shit looking at itself in a mirror." - Lewis Black
    13. Re:Pitch by BluBrick · · Score: 2, Insightful

      That might happen under natural selection, after a few hundred (thousand?) years. But we artificially select these bacteria for their ability to glow in the presence of boom-dust, therefore natural selection is irrelevant.

      --
      Ahh - My eye!
      The doctor said I'm not supposed to get Slashdot in it!
    14. Re:Pitch by Avalain · · Score: 2, Funny

      Except that it doesn't really work that way. Plus, if you DID want to think about it that way you can say the bacteria has already realized that if it glows in the presence of explosives then we will grow large batches of the stuff to spray on the ground. If it decides not to grow then we will just destroy it and make another batch.

    15. Re:Pitch by tsm_sf · · Score: 4, Funny

      And then dog-recovering ponies.

      --
      Literalism isn't a form of humor, it's you being irritating.
    16. Re:Pitch by reverseengineer · · Score: 4, Informative

      In most soils, there live denitrifying bacteria, whose metabolism is based on reducing oxidized forms of nitrogen, eventually turning it back into nitrogen gas which reenters the atmosphere. These bacteria are recyclers, generally getting on by "unfixing" the fixed forms of nitrogen most other organisms rely on to survive, and so tend not to be picky about their nitrogen sources. They have enzymes called flavoprotein reductases that let them get nitrogen from organic nitrates, like from decaying organic matter. It turns out, however, that these enzymes also let them use many of our most common nitrated chemical explosives as a nitrogen source as well. In fact, one such enzyme has even been named PETN reductase, like the PETN that's in Semtex. I'm saying that if you spray liquid explosive on soil, the bacteria that already live there will eat it like candy. The mines would far outlast the spraying, which is exactly the problem- landmines around the world have far outlasted the conflicts they were laid for in the first place.

      The method proposed by this group from Edinburgh actually takes advantage of that process, though. An old landmine or unexploded ordnance is probably going to be slowly leaching explosive out of the weapon. This means that soil near the device will contain the explosive itself, and also nitrites, which are produced as an intermediate step of breaking down the explosive material.

      The group set up a sort of two-factor authorization. They genetically engineered promoters, proteins that bind to DNA and promote transcription of a particular genetic sequence, for two fluorescent proteins. Nitrite ion binds to the promoter for luxAB.GFP, which is a fusion protein of bacterial luciferase and green fluorescent protein. Thus, whenever nitrites are present, this protein gets made, and the bacterium glows a pleasing blue-green color. Not just fluoresces, mind you, but actively puts out light, due to the luciferase part. There is another sequence, for enhanced yellow fluorescent protein (eyfp). That promoter is activated by the presence of trinitrotoluene; the group used computational methods to develop a protein that binds DNA if it is also bound to TNT. Unlike the luxAB.GFP fusion protein, eyfp only fluoresces. It will glow yellow only if higher energy light has been input. So if pure TNT were present, the bacterium would make eyfp, but would only glow under UV light. When only nitrites are present, it actively glows blue. When both are present, the luxAB.GFP dumps light on eyfp, and the bacteria actively glow yellow. And then you call the bomb squad.

      --
      "FDA staff reviewers expressed concern about the number of patients who were left out of the study because they died."
    17. Re:Pitch by B3ryllium · · Score: 3, Funny

      ... on leashes.

  2. How long will it live? by icebike · · Score: 2, Interesting

    It would seem if you could get this strain to survive in the soil for some months you could spray road sides even ahead of the implanting of IEDs.

    --
    Sig Battery depleted. Reverting to safe mode.
  3. Nice idea, but... by TrentTheThief · · Score: 4, Informative

    Exploded mines and artillery shells leave unburnt residue.

  4. Grey Goo 2.0? by Itninja · · Score: 3, Funny

    So can I add this the list of possible humanity-ending catalysts and/or future Michael Crichton novel plotlines? I vote to call it "glow goo" or perhaps simply "bactoswarm".

    --
    I judt got a nre Kinesis keybiartf so please excusr ant egregiou typos.
  5. Oh great ! by bugs2squash · · Score: 4, Funny

    Now we'll all have to be dunked in a vat of this stuff every time I go through TSA security. We get more like sheep every day.

    --
    Nullius in verba
  6. I don't think you comprehend the problem by SuperKendall · · Score: 5, Insightful

    Now they'll either lace the entire field with C4, or they'll start using remote detonators when people move in to disarm.

    The largest problem with land mines is that there are so many in areas where there is no longer any kind of combat - kids or other civilians go in the fields and lose life and limb. This helps with that. We're talking WW2 era stuff here.

    Modern warfare by insurgents is ALREADY past mines, since they don't have an endless amount of money to spend - they already place explosives and use remote detonators when troops come by.

    --
    "There is more worth loving than we have strength to love." - Brian Jay Stanley
    1. Re:I don't think you comprehend the problem by dontmakemethink · · Score: 3, Informative

      I wouldn't say that they're "past" mines, if anything they lack the resources and facilities to make a proper mine, instead what they make are called Improvised Explosive Devices (IED's) which can perform the job of a mine, but can't withstand the elements for decades like a properly encased munition mine can. Sure, many are triggered manually, but a pressure plate trigger can be made from the ringer out of a typical telephone - a piezo transducer, same thing used to measure earthquakes. Wire that through a relay to a diesel-nitrogen cocktail, and it'll take the treads off a tank no problem, but it couldn't last more than maybe 5 years before the batteries die.

      Take a look at the tanks and APV junkyards in Afghanistan and try telling the repair crews there aren't any mines out there. And there are definitely booby traps in buildings where the bacteria could come in handy for sure.

      --

      War as we knew it was obsolete
      Nothing could beat complete denial
      - Emily Haines
    2. Re:I don't think you comprehend the problem by coolsnowmen · · Score: 4, Informative

      Modern warfare by insurgents is ALREADY past mines, since they don't have an endless amount of money to spend - they already place explosives and use remote detonators when troops come by.

      What you've said is not true. I said this to someone else, and at the risk of being modded redundant- BOTH triggers are used in Afghanistan against US troops. Remote detonation falls to the age-old electronic counter measure and it's best defense is a higher power jamer. This is compounded by the fact that the cheapest way to remote detonate is with cellphones, which only operate over a limited & known range of frequencies. Because of this flaw other types of triggers (force/pressure based) are still used (and because for pressure based explosions no enemy has to be physically present ['set it and forget it']).
      (I work in land mine detection)

    3. Re:I don't think you comprehend the problem by Barloe · · Score: 2, Informative

      The US doesn't use the conventional mine anymore. They don't have guys digging holes in the ground and burying them. They use the Volcano mine system. My unit actually got to test them back in the day. These are deployed from 5-Tons, helicopters and artillery shells. They have internal timers in them to auto-detonate after a specified time. The US uses them more as a deterrent than a killing method. They used to come 5 anti-tank, 1 anti-personel per tube. Since '93, they've been changed to all anti-tank, requiring substantial weight/pressure to set them off. As for mine-clearing... it's hard to beat the MICLIC. This bacteria seems most useful in an jungle/urban environment.

  7. Great! by Cornwallis · · Score: 5, Funny

    Yet *another* source of light pollution.

    1. Re:Great! by newcastlejon · · Score: 5, Funny

      Would you be willing to give an arm and a leg just to be able to go stargazing?

      --
      If God forks the Universe every time you roll a die, he'd better have a damned good memory.
  8. Re:This could make things worse... by NeutronCowboy · · Score: 3, Insightful

    The biggest danger with mines is not that they explode - it's that no one really knows where the mines are, and that they are often right around civilian areas.

    Your two scenarios would actually both be a vast improvement over the current situation.

    In the first instance, you just have to get one little corner to detonate, and the entire field should go off. At that point, de-mining via artillery-shelling will actually work. If you meant to say that the mine fields are going to be much denser, great as well - you can actually employ large-scale de-mining equipment and have it be more cost-efficient than the hand-demining.

    In the second instance, people sitting at a remote trigger actually make the mine safer: it means that there are less mines to go around (detonators are scarce, mines are not), someone knows where the mine is and it won't randomly go off when a kid decides to play catch in the field.

    --
    Those who can, do. Those who can't, sue.
  9. Legitimately good idea by Draque · · Score: 5, Interesting

    Am I the only one here who is aware of how bad of a problem land mines are to civilians in many third world countries? The response here seems generally negative, but if this technology helps to diffuse old land mine fields, it would be wonderful. Just because it was planted in WW2 doesn't guarantee that it's become inactive or that it won't kill you now.

    1. Re:Legitimately good idea by KlaymenDK · · Score: 4, Insightful

      No, you're right -- it is a very good idea.

      The problem is, all these critics are a teeny bit right when they say it's not going to work. Alas.

      Not so very many years ago, there was an initiative to grow flowers whose petals turn red if they hit a mine. A lot more practical than bacteria, and it seemed to work very well, too -- but they got booted out of that African country they were testing in rather rough-handedly. It's a sad tale, but the fact is there are more warmongers than do-gooders and these things are immensely difficult to see to fruition.

      I do wish them luck, though.

  10. Re:anyone else see the problem... by CarlDenny · · Score: 2, Funny

    Without RTFA:
    1 - Rocks and nearby puppies.
    2 - Bacteria are asexual. These bacteria will, however, be able to spread an "asexual agenda" among native bacteria, who will begin to glow in the presence of other objects, like discarded cans, to look cool and "green."
    3- Except for puppies, the bacteria are harmless. Unless you like eating gunpowder or landmines.
    4- More landmines! No, wait, they'll be outbred by normal bacteria soon enough.

  11. Re:The hills are alive... by John+Hasler · · Score: 3, Informative

    > The hills are alive...

    True. Topsoil is several percent bacteria by weight.

    > What assurances do we have that the bacteria won't mutate, self-replicate, or
    > turn against its master in the form of some horrendous new super-bug that
    > makes the 20,000 land-mine casualties a year seem like a drop in a bucket?

    None. And the sames goes for the millions of other species of bacteria that infest every square meter of the Earth's surface.

    --
    Warning: this article may contain humor, sarcasm, parody, and perhaps even irony. Read at your own risk.
  12. too erasy in the daytimes.. by Hognoxious · · Score: 2, Insightful

    They don't turn green, they glow green. So you just have to go mine clearing in the dark.

    --
    Confucius say, "Find worm in apple - bad. Find half a worm - worse."
    1. Re:too erasy in the daytimes.. by vlm · · Score: 5, Interesting

      They don't turn green, they glow green.

      Kind of like the goo inside a green chemlight...

      In the old days, if you wanted to do the area denial thing, you had to buy these expensive, heavy, hard to install landmines.

      Then it was discovered you could scare the other guys away merely by using signs that say "landmine". In fact there is a UN standard / requirement for posting landmine signs around a minefield, scary white triangles, if I recall...

      Now, technology marches on, and all you need is a big pack of green chemlights from walmart... crack them, drip the liquid in a field, and instant, cheap, area denial... Its also economic warfare, since mine field clearing is very expensive compared to buying a bunch of chemlights. Its also very demoralizing to the troops to know that glowing stuff might or might not be fake.

      --
      "Science flies us to the moon. Religion flies us into buildings." - Victor Stenger
    2. Re:too erasy in the daytimes.. by TubeSteak · · Score: 2, Insightful

      Now, technology marches on, and all you need is a big pack of green chemlights from walmart

      How many Walmrts are there in Iraq and Afghanistan?
      The insurgents have a steady supply of explosives and there's literally no reason for them to spend money on chemlights vs throwing nitrates around.

      Not to mention that the military has the equipment necessary to distinguish between a glowstick and explosive residue.

      --
      [Fuck Beta]
      o0t!
  13. Minesweeping by dlaudel · · Score: 5, Funny

    I hope that as the bacteria glows, it arranges itself into numbers indicating how many mines are nearby. It should making identifying the mined locations a simple matter of elimination.

  14. False Sense of Security by roguetrick · · Score: 2, Informative

    Detecting mines is great, I'd be pretty damn worried about the ones that arn't detected however.

    --
    -The world would be a better place if everyone had a hoverboard
    1. Re:False Sense of Security by d474 · · Score: 3, Insightful

      Exactly. They have the logic backwards. What if an area didn't get covered in spraying? So that area would be "dark" and they think it's safe? Yikes, that's a false negative. They need to reverse it to avoid that false negative.

      If the bacteria only glow WITHOUT the presence of landmine. That way, at best you get false positives which is less dangerous than a false negative, in this situation.

      --
      Authority questions you. Return the favor.
  15. Re:Dangerous, Tedious, Expensive ? by lbalbalba · · Score: 3, Insightful

    Why is this parent modded 'funny' ? In Eastern and African countries little kids *are* actually being used to detect mines: by blowing them up, and losing their arms, legs, or lives... I do not see what's so funny about that at all...

  16. Re:The hills are alive... by Anonymous+Monkey · · Score: 2, Insightful

    not infest, but inhabit.

    --
    We are the Borg...
  17. Re:I'm surprised that this technology is available by lgftsa · · Score: 2, Funny

    I suspect that if that particular area was crop-dusted with the bacteria, the result would resemble a raggedly cut electroluminescent strip and be visible from space.

  18. Fluorescence != glow in the dark by ground.zero.612 · · Score: 2, Informative

    Just FYI to all the people in this thread misusing the term. Fluorescence require an external source of radiation to glow, but only during that exposure. Think UV light and neon paint.

    --
    "Be prepared, son. That's my motto. Be prepared." --Joe Hallenbeck
  19. Re:Counter-measures by cowscows · · Score: 3, Insightful

    I don't think this invention is being touted as a militarily useful tool. It's intended to help with the cleanup of the bazillions of mines that are still hidden in many many parts of the world where fighting has long since stopped, but the mines still remain behind.

    If the US military needs a path through a suspected minefield, they're not going to spray this stuff, wait a few hours, then send some soldiers out to individually dig up all the green spots. They've got machines that are basically giant armored bulldozers that they can use to cut a straight path through. They also have trucks that basically fire a chain of explosives that clear out a straight path. But it's not feasible to use these techniques for large scale clean up because there's too much ground to cover, and it's a very destructive process.

    So you're probably right that if someone was laying down a minefield this afternoon they could find some fairly easy ways to counter this bacteria. Fortunately, I don't think anyone is going to spend the time and expense to spray explosive residue around a bunch of mines that were buried in WW2

    --

    One time I threw a brick at a duck.

  20. Re:Dangerous, Tedious, Expensive ? by jimbolauski · · Score: 2, Interesting

    A friend of mine was in africa a while back and had noticed something peculure when he visited many years ago, the women always walked behind the men, now many years lator, the men walk behind of the women. When he asked one of the viligers if there was a feminist movement and if women were more more prominent, the viliger said No Land Mines!

    --
    Knowledge = Power
    P= W/t
    t=Money
    Money = Work/Knowledge so the less you know the more you make
  21. Re:This could make things worse... by DesertBlade · · Score: 2, Informative

    A properly laid mine field will not suffer from sympathetic detonation of another mine. Most mines are placed 5 meters apart or more. Artillery is effective against certain types of mines, ones with trip wires or tilt rods, even then I would hesitate going in unless under a more serious threat (ie direct fire).

    A single mine with a remote detonator is barely effective. The whole point of a mine is place it, and forget it. If you need someone (or 2) to babysit it cuts into you combat effectiveness.

    Many modern anti-personal mines have a time that the mine is active. After 2 weeks it goes inert, or explodes in place.

    Being an ex Combat Engineer, clearing minefields in Bosnia I can see the benefit of this technology. It could be a quick way to determine if a field is 'clear' or needs further investigation. Large scale offensive attacks, you can spray this over the battlefield and know shortly if it is clear.

    --
    Half of writing history is hiding the truth.
  22. Great. by SharpFang · · Score: 2, Funny

    Now antiseptics will get on a list of controlled substances used to hide location of mines.

    --
    45 5F E1 04 22 CA 29 C4 93 3F 95 05 2B 79 2A B2
  23. Re:This could make things worse... by Hognoxious · · Score: 3, Insightful

    In the first instance, you just have to get one little corner to detonate, and the entire field should go off.

    Any other genius thoughts you'd like to share with us? Like how it's easy to sink a battleship, all you have to do is make a hole the right size in the right place.

    Seriously, do you think military engineers haven't worked out how to set mines so that 300 mines cause more than one casualty? If one man set off an entire minefield it would hardly be worth getting your spade dirty planting them, would it? You'd do more harm to the enemy throwing the bastard things at them.

    You're not an armchair general. You aren't even a moron. You're an armchair moron.

    --
    Confucius say, "Find worm in apple - bad. Find half a worm - worse."
  24. Re:The hills are alive... by jpmorgan · · Score: 2, Insightful

    Note quite right. The assurance IS the millions of other species of bacteria. All life is compromise, and a bacteria which mutates and becomes ultra-lethal to humans will probably be eaten by its neighbour bacteria, which is more suited for such mundane things as surviving in the soil where they live.

    It's the same reason why the grey-goo scenario is silly. The earth may look beautiful and pristine, but in reality it's a shockingly hostile environment. You've got a corrosive atmosphere (full of nasty oxygen), soaked in a potent solvent (water) and it's infested by machines, tiny and small, which delight in consuming everything around them. You think Mars is a hostile environment? The rovers wouldn't have lasted a month in most of earth's biomes. We just don't notice, most of the time, because evolution (and our own intelligence and experience) has made us very, very, very good at survival.

  25. Re:Dangerous, Tedious, Expensive ? by story645 · · Score: 2, Insightful

    why can't they do something similar and temporarily be celebate to avoid being responsible for all of that misery and suffering?

    The social/cultural issues are for more complex then that. A vast majority of women in these countries can't because they don't have the rights to. The stats on rape in some countries are hideous, and many women are stuck in relationships where they can't tell their partner to use birth control and they can't get out of these relationships for any number of religious/socio-economic/cultural reasons. The guys in many of these countries still have this idiotic notion that using a condom isn't manly and therefore won't, hence why HIV/AIDs rates are also awful in many of these countries. Irresponsible sex is gonna happen 'cause of social/religious/cultural reasons so long as the men in these cultures believe that sex makes them a man and women find that one of the most reliable forms of security/employment is prostitution or being someone's girl.

    But wait, it gets worse. Assuming you can change cultural ideas of sex and gender, birth control isn't the easiest thing to get because of foreign aid policies concerning family planning. In countries where people can barely eat, reliable birth control is often considered an unnecessary expense by many, so the options boil down to condom giveaways and (often illegal) abortions. Currently organizations that provide abortions can get aid, but this stance changes every administration (Bush banned aid to these organizations.) A good number of the organizations that provide abortions are also the ones that provide family planning support and information, like condoms. Then there are the organizations that are limited in what they can provide because the regions are too dangerous to work in or there are religious/cultural barriers to birth control.

    --
    open source modern art: laser taggi
  26. Re:Dangerous, Tedious, Expensive ? by Anonymous Coward · · Score: 2, Insightful

    Its not an addiction you arsehole - its a biological imperative to fuck each other!

    If you lived in a situation where you were dirt poor (not can't afford rent poor - but can't afford the 3p can of beans poor), had absolutely no entertainment beyond watching the occasional soldier get eaten by lions, and generally lived a life of suffering day after day, continuing to struggle only because you don't let the alternative to survival cross your mind; then maybe you would understand the need to find comfort and joy where you can.

    IF it was just a matter of waiting till the shop opens so you can buy more condoms, you would have a point. But if you didn't know when the next truckload of the things was even going to make it the closest town, let alone disseminated down to your village, then you wouldn't be holding your breath or your balls mate and you're disgustingly naive if you think you could or would.

    If we could swap muppets like you for these starving people, and fill the destitute countries with morons that think 'trying harder' is all that is required, we would be able to solve more than one set of problems in one go.