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Anti-Smoking Vaccine Is Nearing the Market
eldavojohn writes "Almost 6 years ago we discussed a vaccine to help people quit smoking as it entered human clinical trials. Now it looks like the finishing touches have been put on a deal that will go into effect once phase III testing of the drug now called NicVAX is completed. NicVAX was developed by Nabi Biopharmaceuticals, who have agreed to license it to GlaxoSmithKline Biologicals; it is expected to complete phase III testing successfully. Others have fallen short of this goal, in pursuit of a smoking-cessation market expected to hit $4.6 billion worldwide by 2016. Nabi has also sold an experimental vaccine for staph infections; and in 2008 we discussed news of a cocaine vaccine."
Willpower, either you own the cigarettes, or they own you.
What's more, there are no side effects
Clearly you've never been addicted to something. Like, ADDICTED addicted, in the sense that your body physically feels different when you try to ween it off.
Don't get me wrong, I think you are right, that quitting is more about a person being disciplined and wanting to quit more than anything else, but to say that you won't feel anything when trying to quit is inaccurate.
Yes, you will get the shivers, and you will get the sweats, and you might even get the shakes. But you gotta fight through that shit.
To me, it sounds more like the story of Equilibrium...
Palm trees and 8
*gives Kratisto nightly heroin injections for a few weeks just to see what happens*
Greylisting is to SMTP as NAT is to IPv4
It's not an either-or. If you own cigarettes, then they own you.
When our name is on the back of your car, we're behind you all the way!
Indeed.
I was a heavy smoker; three packs a day, and I rolled my own (so no filter to douse any of the carcinogenic goodness!) I never thought I'd quit, and really didn't want to. Then, almost nine years ago to the day, I came down with a horribly bad lung infection coupled with probably the single worst ear infection ever. I remember walking up the stairs to the second floor of my apartment would literally take about ten minutes to recover from. I realized at that moment that, while I'd probably get over this one (I was about 28 years old at the time), and I'd get over the next one, and so on, but eventually, sometime in the next fifteen to twenty years my lungs were going to be so fucked up that I'd be stuck with emphysema, probably congestive heart failure and ultimately dying by drowning in my own fluids, and that was if I was lucky, because I could also get lung cancer, and the process would be all the worse.
I threw out my tobacco, left my wallet at home when I went to work so that even if I caved in, I'd have to go out like a bumb on to the street to beg for a smoke. I ate carrots like I was a rabbit with an OCD, just so I had something to do with my mouth. The first week I was still so sick that I couldn't tell withdrawal from everything else that was wrong with me. The second week, it was tough, I was irritable and my mouth seemed to be constantly salivating. The third week it was a little better, and after a month the nic fits were coming only a couple of times a day. I called myself done after a year, and have never picked up a cigarette since.
It was tough at times, but I'm proud of myself that I didn't run to the doctor, stick a patch on, chew nicotine gum or do anything to try to wean myself. I quit cold turkey and never looked back.
The world's burning. Moped Jesus spotted on I50. Details at 11.
Like H1N1 vaccines, this anti-smoking vaccine will help eradicate anti-smoking once and for all, along with all the ill effects it's caused. People will be able to stop worrying about anti-smoking when around other people.
(Brought to you by the people who brought you cooler temperatures, larger sizes, wider width shoes, and cheaper price tags.)
So, this new vaccine... Does it come in a smokable version?
When our name is on the back of your car, we're behind you all the way!
While willpower alone could and should make someone stop smoking, unfortunately not everyone is able to muster that willpower. There are a wide range of reasons people have trouble quitting (on top of the fact it's physically addictive), maybe they have smoked to a long long time or they are very stressed. I'm sure many of these people know it's bad for them and many smokers I've talked to say they want to quit but just can't. I think this vaccine is a brilliant step forward and it will give many life long smokers a second chance to quit. I'm sure there are many people to really have tried everything to quit and hopefully this vaccine will be the last thing they have to try.
From TFA...
NicVAX works by stimulating the immune system to produce antibodies that bind to nicotine in the bloodstream, making the nicotine molecule too large to cross the blood-brain barrier and enter the brain.
So it effects the immune system to recognize some particular foreign matter and deal with it? That sounds like a vaccine to me.
What if you don't need to but like too?
I don't need to have diet pepsi, but I like it.
Having a couple smokes after a long night is no big deal. Unless you live in a bubble you are getting far worse from daily exposure to car exhaust.
This has me worrying about "vaccines" for other drugs. In a century, maybe nobody in the USA will be able to relax with $drug_of_choice, because of mandatory "vaccination" against the effects of any psychoactives.
Palm trees and 8
So it's a nicotine absorption vaccine. Hence the name NicVax. They're preventing absorption, which has the beneficial side effect of helping with addiction.
Unfortunately, this new vaccine is highly addictive. Not to worry though, they are hard at work on a cure for vaccine addiction. It is passed into the bloodstream through the lungs...
I was 1/2 to 1 pack a day for 13 years - then the day before my 26'th birth day i realized that 1 more day and i would have smoked for 1/2 my life and at that point i was a smoker never a non smoker.
looked at the one in my hand - dropped it through the pack i had away and that was it.
Sure i had cravings - i chewed tooth picks for weeks - some times i miss the flavor but to be honest i can't even stand the smell of it any more if i'm around smokers.
Congrats for quiting - and while i'm glad i quit - i'd never be a zealot to go and tell smokers they need to quit, it's a personal thing - but quitting is defiantly a mind over matter thing
'...if only "Jumping to a Conclusion" was an event in the Olympics.'
Rough going, huh? For me, it's quiet the opposite.
I've been smoking for over 20 years, and on occasion I get the urge to quit. The reason has to do with the habit itself. Any habit taken to the extreme or adopted for far too long tends to get less enjoyable as time passes.
When, I do quit, it's typically for a few weeks or maybe a few months at a time. No real withdrawl, except for the day or two, of course. By the end of that period, I come to the same conclusions. Namely, that the "benefits" of smoking (enhanced concentration, relaxation, creativity, etc.) are gone and I want them back. Not need them, but want them. Life, I think, is a bit too ordinary without a vice.
Say what you will about the dangers of smoking, it has its rewards. Besides, what else to do when having a drink, after sex, or when you need to ponder a big idea? And no, nicotine in drug form (as a safer alternative) isn't the answer any more than taking caffeine pills is a substitute for enjoy a coffee. With a cigarette of course. ;-)
As a side note, all cigarettes sold in the US and EU are now required to "fire-safe". That's an oxymoronic term for "they're doused with a chemical to retard burning and prevent fires". The result is a cigarette that doesn't burn properly and tastes like shit. If I do ever quit, it'll be because I've taken up cigars and Scotch.
I started smoking when I was 16, and have been trying to quit ever since.. Once going over a year, only to return, though smoking less. At 24 I tried the patch and gum to no great effect. At 30 I vowed never to buy another pack, and I haven't in 3 years, however I still bum them from friends..
I just can't seem to ever quit entirely, and the idea of a vaccine that would finally let me kick the habit is one I happily welcome.
Live EVERY week... Like it's Shark Week
The only reason why this is necessary is because a compound that already exists is illegal and not profitable.
http://en.wikipedia.org/wiki/Ibogaine
Kind of reminds me of a friend of mine's first foray into quitting smoking. He declared that he was only going to smoke when he was drinking. He did very well with that...the only problem was he ended up getting drunk twice a day.
I coach people through weight loss and smoking cessation. At the beginning I make them sign a contract that says, in part, that they understand this is a life change that will cost them their current friends and social contacts.
Few relationships can survive a life change like that. That's why it's so difficult to quit.
When you smoke or overeat, you chose friends that do the same. And you do activities that revolve around overeating or smoking.
When you quit or lose weight, you find new friends and new activities and you find that your old friends no longer are your friends. Sometimes it's just a gradual thing, but sometimes those "friends" dump loads and loads of guilt on the person trying to change their life, and do everything possible to sabotage the effort.