Microbes That Keep Us Healthy Starting To Die Off

Dr_Ken writes with a quote from Scientific American: "The human body has some 10 trillion human cells—but 10 times that number of microbial cells. So what happens when such an important part of our bodies goes missing? With rapid changes in sanitation, medicine and lifestyle in the past century, some of these indigenous species are facing decline, displacement and possibly even extinction. In many of the world's larger ecosystems, scientists can predict what might happen when one of the central species is lost, but in the human microbial environment—which is still largely uncharacterized—most of these rapid changes are not yet understood. 'This is the next frontier and has real significance for human health, public health and medicine,' says Betsy Foxman, a professor of epidemiology at the University of Michigan School of Public Health in Ann Arbor. Meanwhile, each new generation in developed countries comes into the world with fewer of these native populations. 'They're actually missing some component of their microbiota that they've evolved to have,' Foxman says."

Comments

Re:If we evolved to have them...

[caramelcarrot]

Whether or not we "need" them can only be judged retrospectively, and not after a fairly sudden (in evolutionary terms) change in environment before the consequences have worked out - us having evolved to have them would probably indicate that they give some sort of advantage to not having them.

mod parent up

[bussdriver]

Parent is correct in pointing out this basic failure to recognize the problem with averages in statistics.

In addition, abortions can also be counted as early deaths.

We already save many that would naturally die which has skewed the average even further. If the technology froze, one would expect the average to go down as the genetic defects live long enough to reproduce and increase the defect rates possibly leading to complications medicine can not fully counter.

Just think about it -- a dominant defective trait allowed to continue leads a large demographic of people (or all humans) who have some sort of defect that requires advanced technology to continue the species... The makings of an interesting science fiction story?

NOOOOES

[hldn]

NOT MY MIDI-CHLORIANS!!

Re:Bought the tshirt

[Tezcat]

There is no shortage of domestic cattle, but elephants are endangered because humans want to use and eat them yet make little effort to preserve them in quantity.

I hate to play pedant, but that's a poor analogy. Cattle have been bred to mature quickly; meanwhile the never-fully domesticated Elephants of Africa and India rival humans for their long maturation and gestation periods.

Microbes, on the other hand, are easy to breed in quantity once you have established their optimal developmental environment. Once we work out what we have inside and around us and what we need, we could conceivably tailor our anti-biotic intake based on our inherited and environmental differences.

'Intelligently planned' biotic yoghurt supplements may be the next big thing in preventative health care.
/IANA Micro-biologist

Mostly Harmless

[CuteSteveJobs]

The vast majority of bacteria are either harmless or beneficial to their human host. Only a very small number of bacteria are pathogenic, and most of the time your body does a great job keeping those out. Here's a great book for bacteria spotters, amateur and pro, which tells you how to find bacteria without a microscope.

http://www.cornellpress.cornell.edu/cup_detail.taf?ti_id=3864
http://www.amazon.com/Field-Guide-Bacteria-Comstock-Book/dp/0801488540