The Neuroscience of Screwing Up
resistant writes "As the evocative title from Wired magazine implies, Kevin Dunbar of the University of Toronto has taken an in-depth and fascinating look at scientific error, the scientists who cope with it, and sometimes transcend it to find new lines of inquiry. From the article: 'Dunbar came away from his in vivo studies with an unsettling insight: Science is a deeply frustrating pursuit. Although the researchers were mostly using established techniques, more than 50 percent of their data was unexpected. (In some labs, the figure exceeded 75 percent.) "The scientists had these elaborate theories about what was supposed to happen," Dunbar says. "But the results kept contradicting their theories. It wasn't uncommon for someone to spend a month on a project and then just discard all their data because the data didn't make sense."'"
It's because they are not very good. We could use 75% fewer, and we'd get more done. They picked the wrong major in college.
"The science is settled!" :P
The WIRED piece threads what is written in the summary around the story of how Arno Penzias and Robert Wilson at Bell Labs discovered Cosmic Radiation after being puzzled for a year about background noise on their radio telescopes ... even scraping pigeon poop off their gear as a possible source until they realized the signal was real - Homer Simpson would have said D'OH! ;-)
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"It wasn't uncommon for someone to spend a month on a project and then just discard all their data because the data didn't make sense."
That doesn't mean the data is wrong, it means the /hypothesis/ was wrong, if not the theory, and needs to be modified.
If they're really throwing out date just because it 'doesn't make sense', they're doing religion, not science.
If the data don't make sense according to your theory, you don't discard the data, you discard the theory and work out a new one that fits the facts as you've observed them. TFA says that Dunbar was watching postdocs doing research, and if so, they should have known better. Alas, too many people who call themselves scientists are more interested in proving their pet theory true than in finding out what's actually going on.
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Question *Everything*.
Proving a theory incorrect is often just as valuable as proving a theory correct.
If problems occur as you postulate elaborate hypothesis, then stop piling up the elaborate hypothesis! But be sure and still make available your existing (complex) hypothesis, methodology and unexpected data - preventing others from going down the same path with the same methodology is still highly valuable!
Let's say you're looking at a production and consumption cycle involving neurotransmitters and neuroreceptors of some sort, and the various channels of input and output involved. Your starting presumption you base your hypothesis on is that there is a buildup which triggers an electrical signal to stop consumption and clear the channel. The only evidence you can realistically gather for now is protein density at a certain output channel - but others have worked to ensure this is a reliable approach specifically under these circumstances.
So, you do the specific experiment, trigger the signal, but you get a wildly different result - the stop in consumption occurs, but the protein density does not change at all in the output channel. What actually happened is still unknown, only you haven't verified any correlation with your hypothesis. You still have valuable data, but no mechanism to verify under the circumstances. Either your methodology failed, or you misunderstood what was happening - and the world of knowledge is made larger by either... even if your paymasters won't get happy about the result.
Science is often like throwing pebbles in complete darkness - it takes a lot of stones and close listening to make out a mental picture of the scene - especially when there's a lot of noise already around. Everyone would love it if we could just flip the lights on - but we have yet to invent a light that can see into the inner workings of the functioning brain very well. Gotta keep throwing those pebbles for now.
Ryan Fenton
Is it just me or does this sound like an explanation for some of the Climategate science... But in that case they just massaged or ignored data that didn't agree with their conceptual framework of CO2 causing global warming.
Not that the skeptics are all that immune. They seem to cherry pick data almost as well (just not quite as successfully from the POV of selling their story to the media and political left ..)
When you come up with a stinker of a health care plan that causes your 60th vote in the Senate to wind up 31 points behind the opposition, you call your fuck-up a hard pivot.
"It wasn't uncommon for someone to spend a month on a project and then just discard all their data because the data didn't make sense."
No need to discard perfectly good data when all you need to do is adjust it a little. Don't they know about Mike’s Nature trick?
I can't help but think that Neuroscience needs to calm down, sit back, and take a deep breath. We are examining a system and we are trying to reverse engineer it. We can't start out by trying to create elaborate hypothesis for large systems, we need to go low level and examine the simpler systems. I really think they should hold on to the higher cognitive models for a later time because we can't even completely model C. Elegans and it has the least neurons of any, current, living organism. The way I see it, I total expect their hypothesis to be wrong, because they don't thoroughly understand the low end of the system.
Eat sleep die
...
E pluribus unum
It came late in the year but I would nominate this linked article as the best of slashdot, 2009.
So, when reality is racist, you change it?
I thought World War II empirically proved that the master race is not all its cracked up to be. American mutts and Soviet subhumans kicked the living shit out of the master aryan race. The whole concept of NAZI ideology was that they were the master race, they were not only deserving of victory, but destined, thus, by the most racist rules there are, they proved themselves inferior.
PS. Polish women are the hottest of all European women.
This is my sig.
1)Check your instruments.
2)Check them again.
3)Check the calibration of said instruments.
4)Check system again.
5)Check the software, what assumptions are being made in the software? Are there misplaced decimals? Are your variable selections all appropriately classed/typed?
If you complete this checklist without coming across any failures, RECOLLECT DATA.
Compare new data with old data. What are your applicable/appropriate error measurements?
Perform steps 1 - 5 again.
Your sets of data should help you decide whether it is your hypotheses, or first data sets that need to be thrown out.
If you have been hired to prove something that is mostly false: gut check time. Are you a scientist or a really smart P.R. hack?
As a researcher myself, I certainly hope they don't throw out data too often. There is occasion to do so...sometimes, when trying to establish correlations (admittedly the weakest form of describing a phenomenon, etc), you learn that there is not one. There are times you obtain data that simply says, "These two phenomenon do not strongly affect each other" or "Something we do not know about or have not accounted for is happening all over this mess."
This data could be kept forever in the unlikely event it will prove useful, especially if there is something else going on...could be as simple as a RF/EM noise (which actually happened to a coworker of mine, though I helped to figure out the issue and make alterations to block/filter this noise out.) In previous years, data storage was sometimes at a premium, although lately this is not an issue as HDD climb to extraordinary capacities (until that capacity becomes the norm, then it is merely ordinary.) My point is that rejected or discarded data, at least in my experience, is due to situations such as these.
Things such as "massaging" or ignoring data are not only horribly bad scientific practice, they are a tremendous drag on humanity's progress...you usually learn through failure, but we are led away from the truth by practices such as those.
If the data doesn't fit your theory, the problem is most likely neither with the data (which is fine) nor with your theory (which may also be fine) but with the method you used to produce your data. You probably wired in an incorrect resistor, forgot to close a parenthesis in your Perl code, forgot to add the correct amount of EDTA to your reaction, etc. Then your results ended up looking like shit, and not surprisingly. Doing science is hard.
There's no need to postulate any grand conspiracies or take pot-shots at science in general. This paper is examining real people doing real shit. Most of the time we fuck up, and we're not smart enough to figure out where we made the error.
Indeed. The sort of thing being discussed in TFA is one of the classic themes of late 20th century philosophy and history of science: the disconnect between traditional philosophy of science and the actual practice of science.
Kuhn's Structure of Scientific Revolutions is a good place to start. Just one tiny example of the book: Kuhn goes on about how during normal science, scientists perform experiments to confirm the results that they expect to get. When an experiment contradicts the theory, they don't automatically assume that the theory is wrong; on the other hand, they assume that the experiment was flawed.
Feyerabend and many other philosophers of science take a complementary stand to this by stressing the theory-ladenness of "facts." The claim that the "facts" contradict a hypothesis is never a theory-independent observation, but rather, the conclusion of a different theory that we may overthrow. Feyerabend's classic example is the Tower Argument that Aristotle used to refute the theory that the Earth moves. Wikipedia's article on Paul Feyerabend has a decent, if terse, explanation of this:
Feyerabend goes on to argue that many of our most successful contemporary scientific theories (e.g., heliocentrism and geodynamicism) became so because their Renaissance and Enlightenment proponents held on to them and continued to elaborate on them despite them being contradicted by "the facts," as judged by the application of theories that were better established at the time (e.g., Aristotelian mechanics). That is, new scientific theories often succeed because their proponents keep working on them and improving them despite being contradicting by the "facts"; then as the new theories become stronger and better accepted, people start juding the "facts" by the lens of the new instead of the old, and forget the problems that the new theories were judged to have and never resolved (e.g., things like Newtonian physics not having the same explanatory range as Aristotelian physics).
Are you adequate?
in my experienced - I'm a physical chemist doing atomic resolution condensed phase computer modeling. It's so common that I am troubled when the first analysis gives the answer I expected. I likely spend more time looking for errors when the answer makes sense the first go through. Really.
46 & 2
For example consider seismic data. You've got 50Hz or thereabouts induced in the cables near powerlines, you have wind blowing on the geophones, passing cars or trains, differences in soil above the rock and other sources of noise. A lot of seismic data processing seems to be about throwing away the noisy data and stacking up what is left to limit the effect of noise even furthur.
For other things there are different sources of error which may not be obvious. It's tempting to think it really is 27.23 Celcius becuase the digital thermometer say so, but the little semiconductor measuring probe may be out a full half a degree or more even if it does spit out numbers that fool people into thinking it is more accurate. Sure enough ten seconds later it could be telling you it is 26.8 Celcius when nothing has changed.
If what is actually going on is that a train went past when the reading were taken or if the mains power had a minor spike then nobody really cares. It can take a while to set up a good experiment or set of measurements and some of the initial information collected may be rubbish. I've had bits of mid range steel tested where the results came back with large amounts of tungsten - and instead of compiling some theory about how it got there I've told the lab to kick the new kid off the machine, clean the electrodes and spark test it again.
More likely B ends up on the journal peer review panel because he is a respected pillar of his field, and causes pesky upstart A's paper to be rejected for publication. Forcing the field to wait 40 years for B and his ilk to shuffle off before followers of "crackpot" A can finally get their corroborating data published.
Once again, we see the prophetic genius of Douglas Adams. The investigations described in the article are working out the basic science required to enable the future engineering advance known as the "Somebody Else's Problem Field."
It's pretty rare for everything to go right.
I work with holography. I shine a laser at a piece of film, then develop the film. And presto, I get no image. Do I throw out the theory that exposing film to light should produce an image? No, I assume that I screwed up and go back and start again. It's not uncommon for me to spend 3 months of cleaning, aligning, measuring and so on until I produce a proper image. I then throw away all the "bad" data. Maybe, theoretically, that data could be useful, but there's too many parameters to account for.
"It doesn't matter how beautiful your theory is, it doesn't matter how smart you are. If it doesn't agree with experiment, it's wrong."
- Richard Feynman
"The most exciting phrase to hear in science, the one that heralds new discoveries, is not Eureka! but rather, "hmm.... that's funny...."
- Isaac Asimov
My God, it's Full of Source!
OUTSIDE_IP=$(dig +short my.ip @outsideip.net)
Keep it simple, stupid. Only measure one thing at a time. It is amazing how many people screw that up.
Well, tell me then, just how do you define "race"? What are you testing for? How much melanin is in a person's skin? It's not like there's some "German" gene out there and another "Nigerian" gene and another "Japanese" gene that's common to all people who share a certain heritage. Culture isn't genetic, you know.
And then you changed the question: you said that we can test for certain traits of populations. That's true. But what has that got to do with race? Are you going to tell us that the amount of melanin in the skin correlates with IQ or something? (Even though "IQ" is poorly understood and is something that gets defined as "what IQ tests measure").
I'm pretty sure no one has ever claimed a race of sickle-cell anemiacs, after all. If you put them all in a room, would you really think that anyone would mistake them all for relatives?
Don't think the summary quite found the central point of TFA.
"Dunbar found that most new scientific ideas emerged from lab meetings, those weekly sessions in which people publicly present their data. Interestingly, the most important element of the lab meeting wasn't the presentation -- it was the debate that followed. Dunbar observed that the skeptical (and sometimes heated) questions asked during a group session frequently triggered breakthroughs, as the scientists were forced to reconsider data they'd previously ignored. The new theory was a product of spontaneous conversation, not solitude; a single bracing query was enough to turn scientists into temporary outsiders, able to look anew at their own work."
"I saw this happen all the time," Dunbar says. "A scientist would be trying to describe their approach, and they'd be getting a little defensive, and then they'd get this quizzical look on their face. It was like they'd finally understood what was important."
So that's it: The keys are multiple viewpoints, skepticism, and intellectual competitiveness.
We know where leadership by an anti-intellectual "strongman" who scapegoats minorities and likes boisterous rallies goes
I am calling this neuroscience because it has nothing to do with how the nervous system operates. In this sense I am following the lead of WIRED and/or Dunbar, who can't tell a neuro from a social. From TFA: "Kevin Dunbar is a researcher who studies how scientists study things". OK, he studies things called scientists. scientists are people. The study of people and how they behave is psychology. Science is a social activity. Investigations of social activities are sociology when taken as a whole, or social psychology when considered in terms of the activities of individuals operating within a social group. Dunbar studied social psychology, not neuroscience. There's not a speck of neuroscience cereal in it anywhere. There's very little if any actual social psychology, and psychology, or any science at all. There's talking about science, there's talking to scientists about doing science, and there's watching them do science. There's watching and talking about getting good results and not getting good results, and what people do in the matter case. If Dunbar thinks he's doing neuroscience, I suspect he's not even very clear on science itself, much less the various branches. And it does say he's "a researcher in", not that he's a scientist. I do research in curry recipes from different countries and cultures. I'm a researcher, but not a cultural curriology scientist.
In fact I'll go s far as to say he's a researcher because he knows precious little and is trying to find out basic things, not as is the case with most scientists, someone who knows a fair amount and is trying to build on that with new knowledge. He is apparently not clear on the difference between 'screwing up' and not getting good and/or clean results. This may well be because he was unclear himself as to what it was he was looking at and talking about, and he thought he was just not getting good or clean results, when actually, guess what?
He doesn't let loose any secrets. Anyone can talk to scientists and as what happens if and when things don't turn out as expected. If you get an honest (ie. less concerned with appearances than truth) scientist, anyone would get the same answers. Or one could simply read work from real social psychologists and others who study science and scientists and learn the same things. I myself always recommend Collin's & Pinch's "The Golem" as an illuminating, instructive and entertaining starting point.
And a technical point on methodology: a study that does not find a difference between groups, treatments, whatever, 'fails to reject the null hypothesis' (the assertion that there is no observable difference). It does not prove there is no difference, it merely fails to find one. It fails, but only to find a difference, not to produce a result. It can't say there is no difference, it can only say that it couldn't find one. And, it fails to find a difference, no matter how nicely or hapazardly the data come out. The only studies that "fail" produce no data. Scientists may further fail to find an interpretation, but there's no limitation on trying to figure this out, and it applies to both 'results' (reject null hypothesis) and 'no results' (fail to reject null). Studies that produce data that 'makes no sense' produce data that fails to reject the null. The 'making no sense' is a post hoc evaluation of the data based on an incomplete understanding of the design, collection, analysis or interpretation. Such evaluations are done in science, but they are not part of the scientific process. Therefore when this occurs, it is not a "scientific" result and cannot be taken to reflect in the nature or quality of the work done. If you can't figure what it means, you can't figure out. You cannot say that since you cannot figure it out, then you figure out that it fails. If you think you can take something that 'doesn't make sense' and then say that it makes sense in that it represents a failure, then you've contradicted the assertion that it makes no sense. All you can say is that you don't understand it, and since you d
"I may be synthetic, but I'm not stupid." -- Bishop 341-B
About sex with the woman on top? (Yeah, I know bad joke.)
Did you know 80 to 90% of the moderators on slashdot wouldn't recognize a troll even if one dragged them under a bridge.
I bet Einstein turned himself all sorts of colors before he invented the
lightbulb.
Data that is not published is still valid but wasted. Can we collect this data somewhere more public
even if the data does not fit a well known or lesser known theory - maybe a person viewing the
data can connect the dots. Asimov was correct 99% hard work and 1% inspiration leads to
"hmmm - thats funny"
A little voice in my mind screams:
Given enough eyeballs, all bugs are shallow.
So essentially, Linus ported critical thinking to software development! :-)
Maybe we could backport something to science?