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Organ Damage In Rats From Monsanto GMO Corn

jenningsthecat writes "A study published in December 2009 in the International Journal of Biological Sciences found that three varieties of Monsanto genetically-modified corn caused damage to the liver, kidneys, and other organs of rats. One of the corn varieties was designed to tolerate broad-spectrum herbicides, (so-called 'Roundup-ready' corn), while the other two contain bacteria-derived proteins that have insecticide properties. The study made use of Monsanto's own raw data. Quoting from the study's 'Conclusions' section: 'Our analysis highlights that the kidneys and liver as particularly important on which to focus such research as there was a clear negative impact on the function of these organs in rats consuming GM maize varieties for just 90 days.' Given the very high prevalence of corn in processed foods, this could be a real ticking time bomb. And with food manufacturers not being required by law to declare GMO content, I think I'll do my best to avoid corn altogether. Pass the puffed rice and pour me a glass of fizzy water!"

25 of 766 comments (clear)

  1. Oh God, not the bourbon. by Doches · · Score: 5, Funny

    If it's going to damage my liver, I'm switching to scotch. I'm sorry, Jack, but I just can't take the chance...

    1. Re:Oh God, not the bourbon. by snowgirl · · Score: 5, Interesting

      If it's going to damage my liver, I'm switching to scotch. I'm sorry, Jack, but I just can't take the chance...

      Unfortunately, your scotch and bourbon is likely fortified with a corn product.

      The kind of "duh" think that I'm thinking about here is that, if this corn produces these insecticide-like chemicals, one should have to show that it is non-toxic in humans...

      One could feasibly find a way to splice in genes that would make the product lethal to humans... so if you're "adding" something to the corn, it should be controlled the same as any other food additive.

      Although, people wishing to avoid all GM foods, corn itself has been so selectively bred that it doesn't even resemble its nearest neighbors. It's even moribund if we ever disappear, because its seeds over compete and kill each other off. If you want to talk about crazy amounts of GM, take something that's essentially a grass, and turn it into corn.

      Not like corn provides all its nutritional value unless its treated with a relatively strong-ish base anyways... lime is what's mostly used to break up the proteins on the kernel to produce vitamin B12...

      --
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    2. Re:Oh God, not the bourbon. by Wonko+the+Sane · · Score: 5, Insightful

      ,

      The kind of "duh" think that I'm thinking about here is that, if this corn produces these insecticide-like chemicals, one should have to show that it is non-toxic in humans...

      That's the key: the problem is not the fact that this plant was genetically modified, but rather the specific proteins that it was engineered to produce.

      This distinction will be lost on millions of reactionaries.

    3. Re:Oh God, not the bourbon. by Narpak · · Score: 5, Informative

      Unfortunately, your scotch and bourbon is likely fortified with a corn product.

      Bourbon is primarily made from maize corn, while scotch is primarily barley. This is why it is important to ensure that your scotch is pure single malt!

    4. Re:Oh God, not the bourbon. by tacarat · · Score: 5, Insightful

      There are safe GM foods that have been feeding people for hundreds of years, but it only takes one to go wrong that will cause even the safe GM foods to banned.

      I think the issue is that the old fashion way of genetic modification, or selective breeding, is more tried, true and gradual. Gene splicing and such, however, has more potential for "now that's interesting" events. Given that we're always finding new things that are good or bad in our foods, this is an understandable concern.

      --
      "Common sense will be the death of us all"
    5. Re:Oh God, not the bourbon. by berashith · · Score: 5, Funny

      the question isnt is it safe, the question is how do we make it safe. Obviously, if the corn is modified to not be harmed by chemicals that kill plants, then the solution is to modify people to not be harmed by eating the corn. This way, the deer and other wild population that infiltrate our corn fields will be eliminated along with the weeds that interfere with our farms. Dominion is awesome!

    6. Re:Oh God, not the bourbon. by Anonymous Coward · · Score: 5, Insightful

      But selective breeding is an entirely different beast than the GMO process. Selective breeding allows corn to vary according to the "natural" laws of the corn itself. In GMO corn, companies have actually found a way to break down the barriers that the corn would naturally have to prevent the type of variation introduced. The DNA is altered in such a way that could NEVER happen naturally even after 1,000 years of naturally occurring variation. This at the least is a major cause for concern. Even more concerning is that so little research has been done on the effects of various GMO foods on the human body. Maybe it just gives us more gas. But even, then it would be nice to know.

    7. Re:Oh God, not the bourbon. by chomsky68 · · Score: 5, Informative

      Also, note that the "pesticide" in question is Bt toxin. Bt stands for bacillus thuringiensis. Bt is used in mosquito dunks, pesticide sprays and several other applications. It is not just considered safe for humans, animals and beneficial insects, but is even considered to be ORGANIC! You can spray your crops all day and night with millions of gallons of Bt and not lose your organic certification.

      I disagree with you. When Bt is sprayed it breaks down and that is why there is a 2 weeks 'cool down' period before it is allowed for human consumption. In this case Bt is delivered to your system as is therefore it is not the same as spraying your crops with it.

      --
      I'm Not Antisocial, I'm Just Not User Friendly
    8. Re:Oh God, not the bourbon. by mary_will_grow · · Score: 5, Insightful

      So "The System Worked", uhh, how?

      1. If you RTFA you'd see that Greenpeace lawyers had to go to great lengths and fight a mess of court battles to get at the data that shows this problem.
      2. This corn is out in the food supply, and its not impossible that cross-pollination/etc is causing it to spread to other food sources.
      3. I have no way of determining in the supermarket if either of these 3 varieties, or varieties which include these proteins, are present in the package of corn I'm about to buy.

      You GM fanboys are fighting a straw-man. Folks like me don't hate the idea. I'd like to end world hunger. I'd like my car to run off sugar made from some superplant. What I don't want is some corporation like Monsanto to have no oversight, conflicts of interest all around (HELLO? They _fought_ the release of this information. They'd rather you die from liver disease than see a negative impact on their profits. Why the hell are you coming to their defense?) poisoning our food supply because they didn't want to spend the money or the effort to do it RIGHT.

      Doesn't it bug you that all those left wing GM-hating nutjobs were RIGHT? This is _exactly_ what we feared would happen. Its not the idea of GM we hate. Its Monsanto. And You. And all the other idiots who don't take a second to think about what MIGHT happen if poor oversight is mixed with singleminded financial motivation.

      --
      Why stick up for big business?
    9. Re:Oh God, not the bourbon. by Will.Woodhull · · Score: 5, Insightful

      Actually, it sounds like the system worked to me.

      And if you learn next year that you have some liver damage consistent with the Monsanto Syndrome, will you still feel the same way?

      Since I have a mild intolerance to high fructose corn syrup (it, or something closely associated with it, contributes to my exercise induced asthma attacks which in turn make my bicycling much less fun), for several years I have been scanning ingredients labels for the word "corn". Some kind of processed corn is used in a surprisingly wide variety of foods, and is often near the top of the ingredients list. In the USA, much of this comes from the huge acreages of Monsanto owned agribusiness farms that would be growing one of Monsanto's GM corns, which would then be processed through one of Monsanto's operations before being sold in railroad tanker lots to Kraft, General Foods, Coca Cola, Kellog, Pepsi, Tyson, Little Debby, Hostess, etc. Fortunately the problem that I know about is limited to just HFCS so I don't avoid all corn products and can still eat a lot of stuff from the shelves of Safeway. I'm just pickier about which brands of hamburger relish, salsa, and crackers I buy.

      But if there is anything unhealthy about Monsanto's corn operations, it could potentially affect all USA citizens who were not zealous in avoiding corn (because of severe allergies). That would probably be more than 90% of the USA population. Considering the size of the potential public health problem, I don't think there is sufficient oversight of Monsanto's operations, including its GM corn.

      BTW, Monsanto gets a nice chunk of cash from the Federal Guvmint as a subsidy for growing corn. Although to be fair it should be noted that through their lobbying and campaign contributions they do return a lot of that to the political process....

      --
      Will
    10. Re:Oh God, not the bourbon. by TeXMaster · · Score: 5, Insightful

      "This is _exactly_ what we feared would happen."

      And what "_exactly_" is that, exactly? Do you really think they want to kill humans?

      It's more like they don't care, to the point of criminally trying to withold the information that proves that their products are health hazards.

      --
      "I'm never quite so stupid as when I'm being smart" (Linus van Pelt)
    11. Re:Oh God, not the bourbon. by BrokenHalo · · Score: 5, Insightful

      Selective breeding is certainly well tried and gradual, but "true" is misleading. All you are doing is leading evolution in a direction of your choosing, rather than allowing natural selection to take its course. But you're right in that no amount of evolutionary genetic recombination would result in the spontaneous production of Bt toxin in our lifetime.

      It's worth noting that this is entirely different from the so-called "Roundup Ready" crops which by definition encourage the farmer to use potentially toxic doses of the herbicide. Bt toxin is a pesticide, and the degree of its expression in GM crops is not yet entirely predictable.

      When I first started studying biotechnology 10 years ago, Roundup was commonly regarded as being no more toxic than coffee. We have since learned otherwise, and Monsanto's crude sledgehammer approach to farming practice has gone a long way towards discrediting the biotechnology industry in general.

  2. Re:Why wasn't Monsanto required to reveal this inf by PopeRatzo · · Score: 5, Insightful

    Monsanto did the research in 2000 and 2001, and obviously knew the outcome. So how did they manage to suppress the data and results for 8 years?

    The invisible hand of the free market made the data and research invisible.

    --
    You are welcome on my lawn.
  3. rep of Int Journal of Biological Sciences????? by acidfast7 · · Score: 5, Interesting

    as a scientist, it has two things I dislike listed on its webpage... 1. In a prominent position its "unofficial IMPACT FACTOR" ... ugh. 2. In a prominent position its "UNOFFICIAL impact factor" ... well, if TR/ISI can't find it important enough to tabulate (assuming this is what unofficial indicates), why should we care :( in fact, this is the first time I have heard of the journal ... if the work is more widely useful, we not publish in a more widely-read journal?

  4. Politics of GMO by Kupfernigk · · Score: 5, Insightful
    This demonstrates the European objection to GMO. It is not, as the manufacturers would like to suggest, a Luddite fear of new technology. It is a growing perception that there is no proper oversight of GMO development. In the US, the NIH acts as a counter to the pharmaceutical companies and does a lot of fundamental research. The GMO companies are perceived as being able to carry out inadequate trials, and not make their seeds and research sufficiently available to genuine independent researchers to ensure that the result is properly evaluated. (In the UK, the chief cheerleader for Monsanto is George Bush's pal Tony Blair, which goes a lot of the way to explain our concern. He's lied to us so often that now anything he promotes is immediately seen as being evil.)

    During the 19th century the issue was contaminated food produced by the new breed of large processed food manufacturers: in the early 20th it was the meat packing industry. Now it's Monsanto. In the first two cases it turned out industry was unfit to regulate itself, and bribery of Government officials was rife. But nowadays we regard processed food manufacturers as mostly benign (well, except for the junk food industry), and nobody worries about tinned meat. Regulation in the end was good for the industry. Monsanto needs to stop pissing on anyone who suggests it isn't perfect, and start to come clean. It would be in its long term benefit.

    --
    From scarped cliff or quarried stone she cries "A thousand types are gone, I care for nothing, no not one."
  5. How did I guess this was from Kdawson? by Anonymous Coward · · Score: 5, Interesting

    The study shows no organ damage. This is a lie by the esteemed Slashdot editor.

    The study shows slight changes in some parameters which could be signs of damage. It could also not be. Eating sausages will give you different kidney readings from eating chicken, yet neither sausages nor chicken has been banned. Correspondingly the study says these are "signs of toxicity and not proof of toxicity". I would have expected KDawsons "organ damage" to imply that organ damage had been found.

    Some data seems surprising - there is a significant effect for female rats consuming 11% Monsanto corn, but not male rats or female rats consuming 33%?

    Although I agree that multiple year teasts should be performed, and organ damage checked for. Though it would be extremely surprising if this has not already been done by anyone.

    Of course, since I write this I must be paid by Monsanto or just be evil, since all good-thinking progressives would never question criticism of an evil megacorp like Monsanto.

  6. MOD PARENT UP by schnablebg · · Score: 5, Insightful

    This is exactly right. The reason GMO corn exists and is widespread is that the gov't has incentivized corn production so much that it is practical to grow huge fields of it. This crop monoculture results in the excessive need of pesticides, hence the requirement of "Roundup-ready" crops in the first place.

  7. Re:Why wasn't Monsanto required to reveal this inf by vvaduva · · Score: 5, Insightful

    They do it through lawsuits. They are a very litigious company as they sue their own customers for failing to disclose harvest data and seed information. Since they patended certain varieties of soybeans and corn, you cannot keep seed from one year to the next. Also, a neighboring farmer who has his own non-Monstanto crops contaminated by Monstanto crops are also being sued and asked to prove themselves innocent.

    It's a travesty. I am not opposed to GM foods by any means, but this company's approach to solving problems with their products is completely unreasonable. A class-action suit seems to be the only answer.

  8. Stduy flawed by Orga · · Score: 5, Interesting

    If the GMO corn has been bred for high sugar, as we know that's the main focus, then the rats more than likely consumed more calories which I would expect to have a detrimental effect on most systems in the body. From the study: We note that these unrelated, different non-GM maize types were not shown to be substantially equivalent to the GMOs. The quantity of some sugars, ions, salts, and pesticide residues, do in fact differ from line to line, for example in the non-GM reference groups. This not only introduced unnecessary sources of variability but also increased considerably the number of rats fed a normal non-GM diet (320) compared to the GM-fed groups (80) per transformation event, which considerably unbalances the experimental design. A group consisting of the same number of animals fed a mixture of these test diets would have been a better and more appropriate control.

  9. Re:Wary by BradleyUffner · · Score: 5, Interesting

    If it kills insects when they eat it, then why would it be at all surprising if it was bad for rats or humans too?

    If you spray an insect with water containing soap you will kill it too, are you going to stop taking baths? Salt has some rather nasty effects on slugs, so you better get rid of that. Insects are different that humans.

  10. Re:Science by Pedrito · · Score: 5, Interesting

    why haven't they put it in a really major journal--Nature, Science, PNAS, or something like PlosONE if the whole publication really had to be open access?

    Yeah, their editor-in-chief is only the chief of mammalian genetics at NIH, and their editorial board is a bunch of slackers from the likes of Georgeton, UCLA school of medicine, Mount Sinai School of Medicine, Vancerbilt, Nortwestern, UC, etc.

    OK, I haven't read the paper in detail... Glancing at their results table, it doesn't seem clear cut overall. E.g. there are cases where rats fed 11% GM corn show a response, but rats fed 33% GM corn don't, cases where male rats are apparently affected, but not females, and vice versa. They also don't name the maize they used as a control, so we don't know how accurate it is. Maybe you should read it in detail. FTFA: The raw data have been obtained by European governments and made publically available for scrutiny and counter-evaluation. So, they didn't actually perform the experiments, they're using the results of experiments that others did. It doesn't invalidate your point, but if you read further, I think they realize this:Furthermore, groups of animals were also fed with diets containing one of six other normal (non-GM) reference maize lines; the same lines for the NK 603 and MON 810 tests, but different types for the MON 863 trials. We note that these unrelated, different non-GM maize types were not shown to be substantially equivalent to the GMOs. The quantity of some sugars, ions, salts, and pesticide residues, do in fact differ from line to line, for example in the non-GM reference groups. This not only introduced unnecessary sources of variability but also increased considerably the number of rats fed a normal non-GM diet (320) compared to the GM-fed groups (80) per transformation event, which considerably unbalances the experimental design.

    Yeah, I know, actually reading the article before posting your critical analysis is pretty hard to avoid.

  11. Re:It's the Ends, Not the Means by Fred_A · · Score: 5, Insightful

    GM is an accelerated version of what happens in nature.

    No it's not. It's the artificial manipulation of a genotype to get a desired trait by means that are not very well understood but that mostly work although their consequences are not very well grasped.

    We need it to feed our billions.

    No we don't. Crop rotation and the use of better seeds works much better and with far less pesticides and other toxic chemicals, notably in emerging markets.

    However, a certain company won't get as rich if we go that way...

    --

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  12. Face it: y'all hate it when hippies are right by spun · · Score: 5, Insightful

    Selective breeding is not the same thing as modern genetic modification. Mendel wasn't putting bacterial genes into corn. We've had thousands of years of testing selective breeding. We have had a decade or so of testing bacteria protein laced corn and other genetically modified foods. See the difference? The damn hippies were right: we should have tested this stuff more.

    --
    - None can love freedom heartily, but good men; the rest love not freedom, but license. -- John Milton
  13. need a new word by zogger · · Score: 5, Insightful

    I've seen this a lot on this site (unfortunately). Luddite is tossed around as a swear word to ridicule those who don't understand or see any benefits of modern tech. The opposite exists but we don't have a single word for it, people who automatically trust any new tech to be safe, without any evidence that it is safe, other than the inventor's and corporation's word for it. There's a word used that is close, but doesn't specify "as regards newer tech", that is a "pollyanna". We really need a new word for those who blindly "trust" but never "verify" all new high tech advances.

    This issue with some of the GM corn mods has been known for years now, and dismissed by the big business sycophants/pollyannas. The largest misconception I have seen is equating *cross species modification* with naturally occurring or man made same species hybrids. These get equated all the freaking time by alleged tech savvy people as the excuse to just "trust". The "tech pollyannas" knee jerk automatically trust, based on a starting point of falsehood belief. It's just as loony and stupid as being a luddite based on erroneous or even zero knowledge of the subject.

    I am a farmer and I will say I do NOT trust corporate big ag business (nor ag college academia that relies on the same big business for funding and has tame scientists in and out of the same big business) to be self regulating as to safety concerns nor do I trust the governmental regulators because of the revolving door "jobs" aspect that occur. (exactly the same as occurs with Wall Street/Federal Reserve/Treasury/SEC revolving door jobs). There's WAY too much money involved for there not to be corruption. Just human nature. Just because some person has many letters next to their name, or some official government title, is not any guarantee they are trustworthy as to being non corrupt or "bought off". They are just as likely or not as likely as anyone else, and as the currency units involved go up in number..we should take closer and closer looks as to this trust and verify business.

      It would be nice to trust the system, but I can't the way it is set up now.

    Here's an interesting video on this food subject, on how much trust we should place in huge global ag business and regulations as they exist now.

    http://video.google.com/videoplay?docid=6262083407501596844

    Look at software code. A chunk can be written, looked at, have other people look at it, vetted..few months later they missed something and there is an 0-day.
    Well, that can be patched.

    Can't say the same thing for food stuff once it is planted all over. Won't be any patches once it is out in the wild and air pollination starts spreading it. We are already seeing some of the first minor examples with canola/rapeseed "superweeds". Just wait until there are major examples.

    It isn't a matter of if, it is a matter of when. There will be a hugemongous "whoops..heh heh heh, guess we missed that" excuse mumbling major screwup, by guys in black suits and white lab coats at some news conference, with the global food supply. This corn might be it, who knows, but it is coming.

  14. an African country turned down free GM food by da5idnetlimit.com · · Score: 5, Informative

    Hmm did you hear the rest of the story on that one ?

    They refused "free" gm crops seed and food, worked hand in hand with ONU to alleviate the food crisis and started sowing "normal" traditionnal seeds that were acclimated to their country.

    And now they have almost reached food production independence.

    Can you remind me what happened to the neighboring countries that accepted ?
    They actually sowed some of the grains and now pay the "Monsanto Tax"...and even if short term they solved the problem, they now are in a problematic situation for years (possibly decades) to come.

    Have a look at a documentary called "the world according to Monsanto" and what happened to some south american countries that are now paying millions, if not billions to Monsanto each year. Also have a look at Indian (like in India) cotton farmers and their suicide rates since they switched to GM cotton. One of the worst human tragedy of the decade, because they had to buy fertiliser and RoundUp, got more heavilly in debt and commited suicide when they couldn't repay it all.

    And I'm not even a green activist. I just despise the bastards from Monsanto...

    --
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