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Darwinian Evolution Considered As a Phase

LucidBeast tips a mind-bending report at New Scientist on the latest paradigm-breaking work of Carl Woese, one of whose earlier discoveries was the third branch of life on Earth, the Archaea. Woese and physicist Nigel Goldenfeld argue that, even in its sophisticated modern form, Darwin's theory of evolution by natural selection applies only to a recent phase of life on Earth. Woese and Goldenfeld believe that horizontal evolution led to the rise of the genetic code itself. "At the root of this idea is overwhelming recent evidence for horizontal gene transfer — in which organisms acquire genetic material 'horizontally' from other organisms around them, rather than vertically from their parents or ancestors. The donor organisms may not even be the same species. This mechanism is already known to play a huge role in the evolution of microbial genomes, but its consequences have hardly been explored. According to Woese and Goldenfeld, they are profound, and horizontal gene transfer alters the evolutionary process itself."

51 of 313 comments (clear)

  1. I realize scientists need a breakthrough by Blappo · · Score: 3, Insightful

    I strongly suspect it isn't, nor was it ever, one type of evolution over the other, but a complex interaction between many environmental pressures where both types of evolution played a role.

    --
    Why are so many posts with factual errors modded up?
    1. Re:I realize scientists need a breakthrough by biryokumaru · · Score: 3, Interesting

      Similar to the silly "nature versus nurture" debate, I think the key here is that for different critters, different types of evolution are significantly more dominant.

      --
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  2. Proven example: by Monkeedude1212 · · Score: 5, Funny

    The first 2 parts of Spore are like Horizontal Evolution, and the later parts are all vertical.

    It makes perfect sense. Clearly Will Wright is a genius.

  3. Well duh? by tzenes · · Score: 3, Informative

    For anyone familiar with the Red Queen Hypothesis ( http://en.wikipedia.org/wiki/Red_Queen ) this should be obvious.

    While direct DNA transfer is not the component usually referred to by this "arms race," it is merely an extension of a known theory.

    No one makes a big hype about this theory, because it doesn't say your grandfather was a monkey and piss off the religious nuts

    1. Re:Well duh? by Guido+von+Guido · · Score: 4, Informative

      I can't read the article without registering but I wonder if homosexual behavior could be causing horizontal gene transfer in humans, possibly using viruses as a transport mechanism.

      If viruses are your transport mechanism, I'm not sure you need homosexual behaviour. You may, yes, but there are plenty of other mechanisms for viruses to spread.

    2. Re:Well duh? by wealthychef · · Score: 3, Insightful

      Just why is it that ultra-conservative rants about God or racial superiority or anti-socialism are instantly modded off-topic, troll, and/or flamebait until they sink beneath the thresh hold

      You're seriously asking this question?

      and yet completely off-topic attacks on Creationism in every story even vaguely connected with biology or evolution get modded +5 insightful?

      I think you are exaggerating.

      --
      Currently hooked on AMP
    3. Re:Well duh? by CrimsonAvenger · · Score: 4, Interesting

      I can see that this might be plausible in the early stages of life on this planet where microbes would acquire genes from other microbes.

      I saw an article recently about a species of snail that has acquired the genes for making chlorophyll from the algae it eats. It hasn't yet acquired the genes to make chloroplasts, so it has to eat algae to get enough chloroplasts from the algae to allow photosynthesis to work, but after that it is capable of living with no food other than light.

      So, obviously this is still ongoing, and on larger scales than microbes.

      --

      "I do not agree with what you say, but I will defend to the death your right to say it"
    4. Re:Well duh? by The+End+Of+Days · · Score: 4, Interesting

      Creationism is ridiculed because creationism is ridiculous. Such posts get modded up because people with mod points agree, whether on topic or not. It's not really worth a sociology paper or anything.

      If you really want to defend creationism on /., I salute your bravery. If you are just trying to figure out why people do what they do, I wish you tremendous amounts of luck.

    5. Re:Well duh? by timmarhy · · Score: 3, Insightful

      anyone that thinks the world is 6000 year old and that a big man in the sky planted fossils to test our faith is nuts. it's about as fesible as the flat earth believers, and since they REFUSE to listen to any of the 10000000's of peices of evidence one can only conclude they are in fact crazy.

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    6. Re:Well duh? by renoX · · Score: 3, Informative

      I wonder why this is moderated insightful?
      This is a very different kind of 'acquisition' as the genes for making chlorophyll acquired from the algae are not transferred to its offspring..

  4. Once again by copponex · · Score: 5, Funny

    You know, scientists just keep reforming their ideas until it conforms to observable reality. How can they expect anyone to believe what they say when they're just going to keep changing their minds?

    I prefer my religion. It allows me to conform reality to my ideas.

    1. Re:Once again by BitZtream · · Score: 3, Insightful

      Most people treat what they call science as a religion. They go wild that someone reads a book and believes the far fetched ideas in it, yet they have no problem reading something off wikipedia and assuming its fact.

      The claim is that you CAN test and confirm it, but they don't, they just blindly assume because someone else wrote it down and some others agree with them.

      I really don't see any difference in the way most nutjobs treat science compared/contrasted to the way religions nutjobs treat religion.

      --
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    2. Re:Once again by Cassius+Corodes · · Score: 4, Insightful

      The basic problem is that you don't have infinite time, and as such you have to 'outsource' your knowledge gathering to other people. The problem then becomes one of who do you trust? If you use a heuristic of who has got good results in the past and that leads you to 'blindly' believe in the brand of science - well I can't really find any fault with that. As a researcher, while I know lots about my area, I don't know jack about others so I blindly trust what my doctor, mathematician, physicist tell me. If its an issue of importance I get a second opinion from another doctor etc, but at the end of the day I am blindly trusting them. I don't think there is anything wrong with that.

      --
      Control is an illusion, order our comforting lie. From chaos, through chaos, into chaos we fly
    3. Re:Once again by phliar · · Score: 3, Insightful

      It's not quite 'blind' trust, though. It is reasonable trust, because we've seen that in the past, the methods and models those guys talked about have actually been verified. They invented electronic things that have had a profound effect on humanity. History tells us modern medicine has improved human health immensely (if you're rich enough, of course). And I (an ex-researcher) do know how the scientific method works and what its limitations are. Therefore my "belief" in science is reasonable.

      The best part is that it works for you even if you don't believe in it -- so creationists can still enjoy the fruits of science. Science is better.

      --
      Unlimited growth == Cancer.
  5. I dunno... by Dupple · · Score: 5, Funny

    I pass on my genes horizontally

    --
    Watch those corners
  6. Genetic Engineering by ddxexex · · Score: 3, Insightful

    So does this explain why you can stick "random" genes into a completely different organism and gain traits that wouldn't arise normally? This seems like it'll be very useful in GE if the mechanics of it are explored more.

  7. It's still natural selection by BenBoy · · Score: 4, Insightful

    This really isn't entirely new; Dawkins' book The Selfish Gene is based around the idea that it's individual genes that are selected for, not organisms.

    1. Re:It's still natural selection by phantomfive · · Score: 3, Informative

      Which is nothing more than a restatement of what Darwin said, since a gene is nothing more than an encoded trait. It is the trait that actually matters, not the gene, since the trait is what gives the animal the ability to survive. It doesn't really matter if the trait is encoded as DNA or as biologic etchings on advanced carbon fiber, in either case it is just a representation of a trait.

      --
      Qxe4
    2. Re:It's still natural selection by Locke2005 · · Score: 3, Interesting

      In social animals, it is the survival of the group that is driving evolution, not the survival of individual or their genes. If the survival of each individual's genes were paramount, there would be no homosexuality and no parents killing their own children, 'cause those are pretty much dead-end paths from the standpoint of survival of the individual. Another way of thinking of this is that altruism really does have survival value; just like with army ants, being willing to sacrifice individuals for the good of the group is a good evolutionary strategy.

      --
      I've abandoned my search for truth; now I'm just looking for some useful delusions.
    3. Re:It's still natural selection by trouser · · Score: 3, Informative

      Not the individual's genes, the individual gene. In all plants and animals it is reproduction combined with mutation and recombination that is driving evolution.

      Social animals posses genetic traits which promote social or herd behaviour. In these animals the trait survives because for these animals in the environment in which the trait emerged it increases the chance of survival and reproduction. The gene promotes itself.

      Worker ants are infertile. They share common genetic information with the queen. To protect the nest and the queen increases the chance of propagation of their genes even though they do not reproduce themselves. There's probably a gene for that.

      I have no idea about infanticide but I do recall hearing of a study recently which observed that homosexual men frequently have one or more close female relatives who are unusually fecund. I can't find the link and the research may have since been debunked but the idea is interesting as it suggests the possibility of a gene which increases the reproductive fitness of one individual while reducing the reproductive fitness of another.

      Of course that assumes that being homosexual reduces your chance of reproduction.

      --
      Now wash your hands.
    4. Re:It's still natural selection by SoftwareArtist · · Score: 3, Informative

      Exactly. Evolution is a fundamental mathematical process that applies to information, not organisms. To get evolution, you only need two elements:

      1. An information storage medium.

      2. A mechanism for reproducing that information such that certain pieces of information are more likely to get reproduced than others.

      Once you have those, everything else follows, and it doesn't matter what the precise storage mechanism or copying mechanism is. Horizontal gene transfer is just another way for genetic information to reproduce.

      --
      "I'm too busy to research this and form an educated opinion, but I do have time to tell everyone my uninformed opinion."
  8. It's what's for dinner. by mrmeval · · Score: 3, Insightful

    I am going to come over there and take all your stuff and I'm going to kill you and take your weapons and use them for myself!!!

    If you're really nice and sweet I'll beat the crap out of you and then stick you in my kitchen to make food for me.

    The second is referring to mitochondria not kitchen bitches.

    --
    I'd go on a Vegan diet but the delivery time from Vega is too long. --brownkitty
  9. If you want to do the cross-species thing . . . by StefanJ · · Score: 4, Funny

    . . . you're better off doing it vertically.

    Wearing running shoes.

    And ideally permission of the farmer.

    (beat)

    What?

  10. Still natural selection by Toonol · · Score: 3, Informative

    We've already known that evolution depends on both inheritance of genetic matter and mutation of genetic matter. This is a third mechanism for generating traits, but it stills falls under the umbrella of natural selection. If the change is beneficial, and leads to more offspring, the change will be selected for. Certainly worth study, and we may not have known the full scope of the phenomena, but it doesn't really contradict Darwinian evolution at all.

    As a side note... I wonder if the fact this occurs in nature will silence some of the people objecting to genetic splicing?

  11. Original paper on arXiv by PaulBu · · Score: 5, Informative

    For those who do not care to register for that New Scientist, we still have arXiv... :)

    http://arxiv.org/abs/q-bio/0702015

    Paul B.

    1. Re:Original paper on arXiv by radtea · · Score: 4, Informative

      Thanks, as the New Sensationalist article is full of lies and hyperbole, completely idiotic, transparent falsehoods like, "This code is universal, shared by all organisms, and biologists have long known that it has remarkable properties"

      This simply a lie, as is the claim that 64 combinations producing 20 codons is "redundancy". The reason there are only 20 is well-known to anyone with the least little bit of familiarity with the subject: it is the maximum number of unambiguous combinations, so that if you get six bases in a row there is exactly one way to read them, because no two codons together can result in a third codon being read between them.

      The arXiv article may have something interesting to say, although inter-species genetic transfer has been known to occur amongst micro-organisms for a long time. From a Darwinian perspective the genes available in the environment are just that: another perfectly ordinary part of the environment. Since Darwin's Law depends only on the laws of probability and the fact of imperfect replication, it applies to situations where horizontal transfer takes place just as much as when imperfect copies of genes come from ancestors.

      The details of Darwinian evolution will change a little in the context where organisms are taking genetic resources directly from the environment, but it's still a Darwinian process.

      The weird statements about "questioning if organisms even exist as individuals" are just idiotic marketing hype that pretty much ensure the whole argument is vastly less interesting and important than the authors want to make it appear. Otherwise, why the need for such anti-scientific hype? Unless it is the New Sensationalist characteristically ripping an innocent statement out of context.

      --
      Blasphemy is a human right. Blasphemophobia kills.
    2. Re:Original paper on arXiv by radtea · · Score: 3, Interesting

      http://arxiv.org/abs/q-bio/0702015 [arxiv.org]

      Ok, I've read the original paper now, and it is almost as moronic as the New Sensationalist makes it out to be.

      Their argument is analogous to the following claim:

      I can stand on dry land, or I can swim in the water, but there is the broad swath of territory that is neither dry land nor water so deep I can do nothing but swim in it. Therefore, the concept of "land" (or "water") may actually be completely useless! Aren't we clever?

      Scientists have a tendency toward various kinds of conceptual realism, where they think that there is exactly one way to properly understand the universe, and the entities picked out by that way are "real" and no others are. When they find a case that they can't crisply classify under the existing concepts there are two moves: the smart one, that refines existing concepts and introduces new ones to deal with the boundary cases; and the idiotic one, that claims that since the existing concepts don't deal well with the new case, they must not pick out anything "real" after all and should be thrown away.

      That the biological species concept fails in various ways has been known for a long time. They are now pointing out that certain criteria that would normally be used to delineate individuals might also fail under some circumstances. To this I say: big deal. The biological species concept, like the concept of Newtonian mass, is still incredibly useful in understanding reality under a wide range of circumstances, which is all a scientist can hope for. If their new concepts--which they don't really offer--transform smoothly into the biological species concept in the appropriate circumstances I'll be interested. Otherwise, they're just gabbling.

      --
      Blasphemy is a human right. Blasphemophobia kills.
    3. Re:Original paper on arXiv by rgmoore · · Score: 4, Interesting

      This simply a lie, as is the claim that 64 combinations producing 20 codons is "redundancy". The reason there are only 20 is well-known to anyone with the least little bit of familiarity with the subject: it is the maximum number of unambiguous combinations, so that if you get six bases in a row there is exactly one way to read them, because no two codons together can result in a third codon being read between them.

      Except that isn't true. Every one of the 64 possible 3 base sequences is a valid code for either an amino acid or a stop codon. Some viruses take advantage of this by overlapping protein coding regions, with different proteins being coded by reading in different frames. In eukaryotes, there are some genes that can code for proteins with very different sequence regions because an exon skipping splice variant results in a frame shift that codes for a completely different sequence.

      A more significant complaint about the "This code is universal, shared by all organisms" quote is that it isn't universal. There are small differences in the genetic code between genomes. NCBI lists no fewer than 23 different versions, but given that a tiny fraction of all species have been studied there are undoubtedly many more minor variants. An especially interesting case- and the place that difference in genetic codes were first discovered- is that human nuclear and mitochondrial sequences use slightly different genetic codes. The mitochondria even have their own distinct ribosomes.

      --

      There's no point in questioning authority if you aren't going to listen to the answers.

  12. I wrote about this a while ago by presidenteloco · · Score: 3, Interesting

    The notion that life probably started by weak, stochastic replication of families of similar molecules.

    By weak, is meant that the replication of the molecule/structure is more imperfect from generation to generation
    than in present day life, and so a class of similar molecules (life codes) is being continued through time
    rather than a singular particular molecule (same genome).

    If this origin theory were true, we would expect the replication capability (continued recreation of imperfect but still somewhat replication-capable molecules)
    to be robust to change of DNA/RNA even today.

    By stochastic, is meant that such imperfect replication is likely to only be stochastically successful in a huge population of the
    initially highly approximate (i.e. weak) replicator molecules.

    In other words, we would not expect this proto-life to be as reliable at being able to continue (or to always reliably grow by recruiting
    surrounding matter into high-fidelity copies.)

    So we might expect these proto-life molecule soups to initially just contain in some regions higher than expected probabilities,
    stochastically, from time to time, of weak-replicator molecule classes.

    Perhaps there is a binary threshold of replication probability and fidelity at which the process self-sustains reliably in the
    generality of environment it finds itself in. Life catches fire, and cannot easily be stopped at its matter and energy recruitment
    game from that point on.

    --

    Where are we going and why are we in a handbasket?
  13. Re:Capitalism? by Chris+Burke · · Score: 4, Informative

    However, I've always read Darwinian evolution as "survival of the fittest", with no qualifier as to how you go about surviving.

    "Survival of the fittest" aka Natural Selection was half of Darwinian evolution. This was the half about how traits were selected for in the environment.

    The other half was how an organism's traits came about, and his theory was that traits were passed from parents to offspring in the reproductive cells via some biological mechanism that allowed for combination and mutation. Eventually we discovered DNA, the very biological mechanism in question that had traits like Darwin predicted (though Mendel was the one who really nailed down the probably behavior of this then-unknown mechanism).

    "Horizontal" evolution doesn't fall into that category, though. So it's not "Darwinian". Even though natural selection (obviously) still applies to what gene transfers result in successful organisms.

    As the summary mentions, this is well known in micro-organisms. In fact as far as I can tell they aren't arguing that it applies to anything but microorganisms. The argument seems more like that because these are the most common life forms on earth and also the oldest, Darwinian evolution is not the most common or dominant form of evolution.

    Which is a good point. Though really, as far as what affects us and other sexually reproducing creatures, Darwinian evolution is still 'it' more or less. The real importance of this breakthrough is in studying how the evolutionary mechanisms themselves evolved -- evolution is of course not immune to evolution. ;) This is going to be a powerful way of thinking about how early aspects of DNA came to be.

    But just to be clear -- if someone says that this proves Darwin was wrong, evolution is a sham, and therefore their beliefs are probably right, go ahead and slap them. :) All this means is that evolution is even more complicated and powerful than previously thought.

    --

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  14. Here's A Tip, Folks by MightyMartian · · Score: 4, Informative

    Here's a tip, folks. The minute you see some science journalist use the word "paradigm", as in "paradigm shift" or "paradigm breaking" you can be quite certain that what follows will be neither.

    Horizontal gene transfer has been known about for decades, and the notion that the root of the tree of life is more a tangle of interconnecting branches has pretty much been accepted for some time now. We know that particularly with prokaryotes, horizontal transfer happens, and that while more difficult with eukaryotes, can still happen (ie. endo-retroviral insertions). It is yet another facet of evolution, not some independent force.

    --
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    1. Re:Here's A Tip, Folks by Dalambertian · · Score: 5, Insightful
      Here's a protip I've learned from watching the internets and reading your first comment: The moment anyone brings to light something most people have been ignoring, there's always someone who comes along claiming that there's nothing new to see here and that anyone who doesn't know that is clearly misinformed. I'm sorry, but I've never heard of this theory before, and I daresay I'm not the only one. So, please, stop trying to take away my sense of wonder.

      Sincerely, the misinformed

    2. Re:Here's A Tip, Folks by icebike · · Score: 5, Informative

      Horizontal gene transfer has been known about for decades, and the notion that the root of the tree of life is more a tangle of interconnecting branches has pretty much been accepted for some time now.

      Further it has nothing at all to do with Darwinism.

      A mechanism of gene transfer plays no role in the "Survival of the Fittest" (a phrase coined not by Darwin, but rather by Spencer), or natural selection. Its not germane.

      Natural Selection is a winnowing process, and a mutation amplifying force, but says nothing about the acquisition or dispersion of said mutations. It was never meant to.

      --
      Sig Battery depleted. Reverting to safe mode.
    3. Re:Here's A Tip, Folks by MightyMartian · · Score: 4, Interesting

      I'm not trying to take away anyone's "sense of wonder". I'm saying that horizontal gene transfer is one known way in which variation can occur. Remember, evolution requires only that there be variation in populations. For the most part, that variation will either be in allele frequency, but sometimes is also mutational, sometimes due to neutral drift, and probably with considerably less frequency due to horizontal transfer. It ain't new, and neither is trying to make a well known phenomena sound exciting and "paradigm shifting" by announcing it to the world.

      Man, but I hate science journalism.

      --
      The world's burning. Moped Jesus spotted on I50. Details at 11.
    4. Re:Here's A Tip, Folks by icebike · · Score: 5, Informative

      I fail to see the point of confusion.

      Acquisition of a trait (by whatever means) would never amount to a significant percentage of the gene pool of an organism unless it proffered some usefulness. Mutation or horizontal genetic transfer are but mere mechanisms. Darwinism discusses the overall process, not the details.

      How that transfer took place is mere details. When that transfer takes place is not fixed in time. Horizontal transfer still exists in larger and more complex organisms and their symbiotic partners.

      --
      Sig Battery depleted. Reverting to safe mode.
    5. Re:Here's A Tip, Folks by camperdave · · Score: 5, Insightful

      In other words, the tree of life is a banyan tree.

      --
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    6. Re:Here's A Tip, Folks by Cassius+Corodes · · Score: 3, Insightful

      Depends who you mean - the article says most biologists didn't pay much attention to this and I think that is wrong. However to say most laymen did not know about this is probably correct. Also like GP I hate the phrase "paradigm shift" as I find its often brought up by purveyors of woo.

      --
      Control is an illusion, order our comforting lie. From chaos, through chaos, into chaos we fly
    7. Re:Here's A Tip, Folks by syousef · · Score: 3, Insightful

      Here's a tip, folks. The minute you see some science journalist use the word "paradigm", as in "paradigm shift" or "paradigm breaking" you can be quite certain that what follows will be neither.

      Thank goodness! Relativity and Quantum Mechanics make my head hurt. With this wonderful insight you've provided I can crawl back into my Newtonian clockwork universe shell and ignore them! ;-)

      More seriously. Pardigms do "shift" and get "broken". It's just that almost every journalist wants to sensationalise their news piece to sell it. That doesn't mean there aren't genuine breakthroughs. Just that you can't trust a journalist to tell you about them.

      --
      These posts express my own personal views, not those of my employer
    8. Re:Here's A Tip, Folks by Alphathon · · Score: 3, Informative

      First, if you wish to be taken seriously in an intellectual discussion, please learn the difference between your and you're. I am a grammar nazi (not that I'm proud of it - I can't help it and I blame my mum because she's even worse than I am :S) but things like that show a lack of thought behind posts.

      Anyway, back on topic. Icebike did not say that horizontal gene transfer cannot influence fitness, but that the mechnaism itself has no effect. What has the effect is the genes, not how they got there.

      Here's evolution by natural selection in a nut shell - organisms are different; some organisms are more suited to their environment than others; better ones survive and reproduce - their traits survive.

      Furthermore, Darwin had no knowledge of genes, as they were not known of in his day. This means that his theory does not even touch on the cause of the differences, but focuses on how they propogate. Thus Icebikes statement "Further it has nothing at all to do with Darwinism." because, as I said, Darwinism has nothing to do with genes.

      We now know how different traits come into being and what causes the changes (if not completelly then at least to a large degree - there's always more to be learned) so we can fill in the gaps, but that is evolutionary theory, not darwinism (the latter is a part of the former).

    9. Re:Here's A Tip, Folks by BrokenHalo · · Score: 5, Informative

      I'm sorry, but I've never heard of this theory before, and I daresay I'm not the only one.

      OK, here you go, then: Prokaryotes (i.e. bacteria, archea and so forth), by virtue of the comparatively "exposed" genetic material (not condensed or "bunched up" like ours typically is) and because of the structure of their cellular membranes, are very capable of "scraping up" any loose genetic material that may be lying around (e.g. as a result of cellular lysis). If these nucleic acids confer an evolutionary advantage, they are propagated in successive generations. This is why, and how "superbugs" like MRSA are thought to have evolved.

      Microbiologists have used this feature for decades in the genetic engineering of bacteria to induce desired characteristics. The process is much harder and more complicated in eukaryotic (e.g. animal or plant) cells, but it can and does happen.

    10. Re:Here's A Tip, Folks by svyyn · · Score: 3, Interesting

      Acquisition of a trait (by whatever means) would never amount to a significant percentage of the gene pool of an organism unless it proffered some usefulness.

      Though a popular view, that's not true. Assuming 'trait' means an independent mutation, then that trait can go to fixation in a population by simple chance (the expectation is that this happens to 1/2N mutations). Also, genes that are physically near each other on the genome tend to be passed as a set. Therefore, it is likely that a completely neutral, or even slightly disadvantageous mutation, that happens to be near an advantageous mutation (or a mutation that won the mating lottery and is heading toward fixation) will also be propagated throughout a population. There are other more esoteric reason why this could happen too, but a strictly adaptationist view of evolution was dropped in the 60s.

    11. Re:Here's A Tip, Folks by icebike · · Score: 3, Insightful

      1) Traits may be inherited. Clearly traits had to arise from somewhere, either mutations, the action of the environment physically changing an organism, acquired by horizontal gene transfer, or some as yet undiscovered method.

      Darwin never insisted that inheritance was the ONLY method of trait acquisition. Even he was was able to imagine backward a few million years and realize that the slight differences that were subsequently amplified had to have been acquired by some means he did not document. He often ruminated on this inability to quantify the source.

      This so called new theory does no violence to Darwin's basic premise.

       

      --
      Sig Battery depleted. Reverting to safe mode.
    12. Re:Here's A Tip, Folks by ultranova · · Score: 3, Insightful

      Understandable, since Dawkins seems to view evolution almost religiously, so of course any deviation from dogma would be rejected as heresy.

      --

      Forget magic. Any technology distinguishable from divine power is insufficiently advanced.

  15. Viruses by Arancaytar · · Score: 4, Insightful

    Horizontal transfer isn't really over, either - we still have retroviruses.

  16. Gene Synthesis by mosb1000 · · Score: 3, Interesting

    One of the big difficulties I have in understanding evolution is the process of gene syntheses. It seems reasonable that over time certain combinations of genes can win out over others, and certainly in bacteria you see this horizontal gene transfer happen all the time. You even see it in plants now thanks to genetic engineering, and before that you saw it in a more limited way thanks to viruses and cross-pollination and things like that. But all these things have to do with the transfer of genetic information between life-forms.

    The question in my mind is where did all the genes come from in the first place. Proteins are complex macro-molecules. It's not like one protein that catalyzes one reaction can simply mutate into a different protein that catalyzes a different reaction. It's more of an all or nothing thing. It doesn't seem like you would ever see transitional "evolutionary" forms of proteins for that reason. Worse still, you can't (as far as we know) start with a working a protein and reverse-transcribe from it into a strand of DNA or RNA that could code for it.

    What do you think?

    1. Re:Gene Synthesis by brit74 · · Score: 4, Interesting

      It's not like one protein that catalyzes one reaction can simply mutate into a different protein that catalyzes a different reaction. It's more of an all or nothing thing. It doesn't seem like you would ever see transitional "evolutionary" forms of proteins for that reason.

      There are instances of proteins evolving into something that does something different.

      "Biologists have shown that independent but similar molecular changes turned a harmless digestive enzyme into a toxin in two unrelated species -- a shrew and a lizard -- giving each a venomous bite."
      http://www.sciencedaily.com/releases/2009/10/091029125532.htm

      Generally, what happens in these cases (where a protein evolved into a different protein with a different function) is that the original DNA sequence gets duplicated, and then one of the duplicates starts evolving (and the other copy continues to serve the same original function that it had earlier). One of the things that evolutionary biologists do is look at protein sequences and find similar sequences within the same organism. Very often, there's a tree-like structure showing multiple variations on a single protein within an organism. For example, humans have multiple copies/variations on the hemoglobin gene. They're either inactive or active at different phases in a person's life. Example:

      "Fetal hemoglobin, or foetal haemoglobin, (also hemoglobin F or HbF) is the main oxygen transport protein in the fetus during the last seven months of development in the uterus and in the newborn until roughly 6 months old. Functionally, fetal hemoglobin differs most from adult hemoglobin in that it is able to bind oxygen with greater affinity than the adult form, giving the developing fetus better access to oxygen from the mother's bloodstream."
      http://en.wikipedia.org/wiki/Hemoglobin_F
      http://en.wikipedia.org/wiki/Hemoglobin#Types_in_humans

      There's also the case of the fish antifreeze that evolved from non-protein-coding DNA:
      "Scientists at the University of Illinois have discovered an antifreeze-protein gene in cod that has evolved from non-coding or 'junk' DNA."
      http://www.sciencedaily.com/releases/2006/04/060404090831.htm

  17. Let me explain... by denzacar · · Score: 3, Insightful

    Just why is it that ultra-conservative rants about God or racial superiority or anti-socialism are instantly modded off-topic, troll, and/or flamebait until they sink beneath the thresh hold and yet completely off-topic attacks on Creationism in every story even vaguely connected with biology or evolution get modded +5 insightful?

    Same reason why at least someone will look favorably on the fact that you may have served pizza for desert, while you will be forever banished from the kitchen (and other places) if you serve up a pile of dung.

    Both are off-topic, but while one still satisfies the basic requirements - the other is a pile of shit.

    In the case of pizza - it is still food; in case of pointing out the errors of creationism - it is still a discussion about evolutionary theories, it only digresses towards pointing out the wrong ones.
    Creationism and a plate full of dung - a pile of shit.

    --
    Mit der Dummheit kämpfen Götter selbst vergebens
  18. darwin didn't know the details? shocking! by panthroman · · Score: 4, Insightful

    Have Woese and Goldenfeld a brilliant new idea? All they're saying, I think, is that "parent" and "child" are the appropriate units of selection only when genes are passed vertically: from parent to child. They're suggesting that horizontal gene transfer is underrated as a historical evolutionary force.

    Agree or not, it hardly undermines Darwin. Genes weren't known in the 19th century. Darwin didn't have a clue about genes, so we're gonna knock him for being "wrong" about it? I mean, was Jesus wrong about genes, too? It's anachronistic silliness.

    Science is fundamentally dynamic. Any science that hasn't progressed in 150 years ain't doing too well. (Dear creationists: stop calling us "Darwinists." We've moved on.) I mean, The Origin came out in 1859, for crying out loud! Darwin was more brilliant, more insightful, and rightly more famous than I'll ever be. But if we both had to take a biology test right now, I'd kill him.

  19. Re:You raise an interesting point here by Joel+Brown · · Score: 3, Insightful

    It is important to note that the idea the "science is about truth" is a common intellectual error of modern society. Science has nothing to do with finding truth or learning how the universe actually works or anything of the sort. Science is about building models of observable natural phenomena. The point of the models is to conform with what is observable and hopefully predict something that hasn't yet been observed, but which can then be tested and seen to work. Good science is about building models that work well, and refining models that don't. Poor science is about building models that sound like they ought to work but don't conform to observation. Really lousy science is about building models that can't be tested against reality and don't predict anything. Are you listening evolutionary psychologists? Take for example: "survival of the fittest" - This is a model for the mechanism by which one organism gets to spread its genes. It sounds perfectly plausible, almost indisputably sensible. But what does it mean? The key is the word "fittest". "Fittest" means best able to survive. So the model mechanism is really survival of the one ones that survived. Now it sounds trite and unhelpful, which it is. How do we know it's not "survival of the luckiest" or "survival of every n-th one"? We don't, but survival of the fittest is more appealing to our cultural sensibilities, so we go with that. If you remember that science is about coming up with ways to get your head around nature, rather than about figuring out what nature really is, then you don't get caught in the trap of "how can you trust science?" You only have to trust it as far as it is working for you, you don't have to build your world view on it.

  20. Re:You raise an interesting point here by Opportunist · · Score: 4, Interesting

    Science is not the search for "truth". It's the search for an explanation. Unfortunately, it has become the new religion, people simply believe what some scientist says as gospel and, as you identified, are then frustrated and irritated if it is found to be incomplete or utterly false.

    That is not how science is to be treated. Science does not have all the answers. Science is the search for those answers, not the answer itself. Science is not about believing, it is about doubting. About offering a theory and offering ways to test that theory. Especially the latter part is often overlooked by people. A good theory offers an angle to falsify it. I may state that at the center of a black hole is cake. Just to make all the Portal players happy. And while we're at it, before the big bang there was a flat world carried by a turtle. You cannot falsify either theory. You cannot test them. So they have to be true. Right? False! Both are non-theories. They have zero scientific value. At least until we somehow find ways to test them.

    So presenting any theory that offers no vector of testing is, scientifically, worthless. Unfortunately, that's not easy to convey to people. They want explanations. And science cannot offer them. Science is not about certain answers. It is about questioning theories.

    --
    We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
  21. Re:Capitalism? by ppanon · · Score: 3, Insightful

    Which is a good point. Though really, as far as what affects us and other sexually reproducing creatures, Darwinian evolution is still 'it' more or less. The real importance of this breakthrough is in studying how the evolutionary mechanisms themselves evolved -- evolution is of course not immune to evolution. ;) This is going to be a powerful way of thinking about how early aspects of DNA came to be.

    I'm not so sure about that. Endo-retro viruses might still be a major factor for more complex organisms and even chordates. I've been wondering about whether super-retro viruses that can cross-infect multiple species while carrying secondary genetic payloads would be a possible agent for punctuated equilibrium.

    It's interesting that there are people with varying degrees of immunity to retro-viruses like AIDS. While AIDS is not very contagious, other retroviruses could be much more easily transmitted, so you would think that retro-viral resistance would be a very beneficial and common mutation, however it appears to be quite rare. Why? Well, it's possible that such mutations have drawbacks that are more frequently a disadvantage than the immunity advantage (as a parallel, sickle-cell and Thalassemia resistance to malaria), it also might be because susceptibility to retro viruses provides a significant evolutionary advantage in the Red Queen's race for complex organisms just as horizontal DNA exchange does for bacteria.

    --
    Laissez lire, et laissez danser; ces deux amusements ne feront jamais de mal au monde. - Voltaire