Slashdot Mirror


Snails On Methamphetamine

sciencehabit writes "Science answers the question: What happens when you put a snail on speed? From the article: 'The results suggest that meth improves memory, something that has been previously observed in creatures with large, complex brains like rats and humans. But since the snails store their memories in a simple, three-neuron network, the team hopes that studying the meth effect in these gastropods will help pinpoint how the drug's memory magnification powers work.'"

30 of 93 comments (clear)

  1. Interesting by davidsinn · · Score: 5, Funny

    Three neurons for a memory. Sounds like the congress.

    1. Re:Interesting by ragefan · · Score: 2, Funny

      Clearly due to all the meth and coke on the cash.

    2. Re:Interesting by Anonymous Coward · · Score: 2, Funny

      Three neurons for a memory. Sounds like the congress.

      I think you are thinking of morons, not neurons.

    3. Re:Interesting by ConceptJunkie · · Score: 3, Funny

      OK. It's really simple.

      "Libraries of Congress" is a measure of information. It is unit based on the amount of printed data stored by the Library of Congress expressed in bytes. It's value is 10 terabytes, according to some random website I googled, but that value seems awfully low to me unless you're talking strictly text data.

      "Congress" is a measure of corruption and incompetence. It is a unit based on the measure of immoral and destructive acts committed by the U. S. Congress expressed in terms of bogon flux. A bogon is a quantum of stupidity (also referred to as an "anti-cluon" or "tau-moron"). All stupid and many evil people emit a bogon flux, which increases proportionally with the level of stupidity or petty evil a person commits. For instance, if a 10-year-old calls you "gay" because you like classical music, he is emitting approximately 1 bogon per cm^2*s (also referred to a having a "bogosity of 1"). If your boss forces you to work late and miss a concert because you neglected to put the new covers on your TPS reports, he has a bogosity of around 1000. A bogosity of a million (10e6) has been officially designed in the SI system as a "darl".

      Andy Dick registers in the 5 to 8 darl range. Steve Ballmer averages about 20 darls, but researchers measured a spike of nearly a kilodarl when he performed his "monkeyboy" dance. Although the U.S. Congress has been measured at bogosity levels as low as 800 kilodarls, measured shortly after they balanced the budget in 1998, all the way to well over 300 megadarls in the aftermath of 9/11 to nearly 4 gigadarls measured during the passage of the latest "stimulus" bill, a "Congress" was traditionally (and informally) considered to represent a bogon flux of 1 megadarl. This began to be regarded as woefully out of date by 2003. In recent years, the round number of 1 gigadarl has become the commonly accepted value of "Congress", which is equal to approximately 6.4 Kim Jong-Ils or an even six-pack of Mahmoud Ahmadinejads.

      --
      You are in a maze of twisty little passages, all alike.
  2. What about the converse? by Locke2005 · · Score: 4, Funny

    What happens when you put a greyhound on qualudes?

    --
    I've abandoned my search for truth; now I'm just looking for some useful delusions.
    1. Re:What about the converse? by Anonymous Coward · · Score: 3, Funny

      What happens when you put a greyhound on qualudes?

      Same thing as if you have snails on meth. WALK FOR YOUR LIVES!

    2. Re:What about the converse? by Farmer+Tim · · Score: 3, Funny

      It slows down enough for you to see the individual colours.

      --
      Blank until /. makes another boneheaded UI decision.
  3. Practical Usage by diakka · · Score: 4, Funny

    Maybe this bit of science doesn't have much practical usage just yet, but maybe they could somehow exploit the improved memories of these snails on meth to prevent dups right here on Slashdot.

    --
    -- Knowledge shared is power lost. -- Aleister Crowley
    1. Re:Practical Usage by Farmer+Tim · · Score: 3, Funny

      The snails are busy. How else do you think everything ends up here a week late?

      --
      Blank until /. makes another boneheaded UI decision.
  4. This... by ArsonSmith · · Score: 5, Funny

    This is what happens when you put scientists on pot.

    scientist1: "DUDE!!! what would happen if we took a snail, (pause) and gave him speed?"

    scientist2: "PHHAAAA HAHAHAHAHA, lets' get to the lab!!"

    --
    Paying taxes to buy civilization is like paying a hooker to buy love.
    1. Re:This... by Mindcontrolled · · Score: 2, Funny

      Oh man, how did you have my lab bugged during my PhD work? Seriously, dude, I though that stuff was long buried and forgotten...

      --
      Ubi solitudinem faciunt, pacem appellant.
    2. Re:This... by Onymous+Coward · · Score: 2, Informative

      No, this is what happens when you put scientists on pot:

      Mr. X.

    3. Re:This... by EdIII · · Score: 3, Insightful

      I think someone needs to review their protocols for getting messed up then.

      You aren't doing it right man.

  5. Science has come so far. by UncHellMatt · · Score: 2, Funny

    I can imagine these are the same folks who thought it was "BRILLIANT!" to blow smoke in their dog's face with a one hitter. However the "On meth it does" ads will get much more amusing. "A snail doing 60mph down the highway isn't normal. But on meth it is..."

    All joking aside, being no biologist I do wonder about the validity of such experiments. Anyone able to educate me on how they think that the effects on so different a neuron network will yield important information about how humans store / process memories? Are our brains THAT similar to ones found in a snail? Congress not withstanding, of course.

    1. Re:Science has come so far. by logjon · · Score: 4, Informative

      It's easier to monitor three neurons than it is the complex neural networks of larger life forms. Kind of the same way it's easier to administrate a three-computer home network than it is to administrate google's infrastructure. Did you really need this spelled out to you?

      --
      The stories and info posted here are artistic works of fiction and falsehood.
      Only fools would take it as fact.
    2. Re:Science has come so far. by confused+one · · Score: 5, Insightful

      Well, since we're only just starting to understand how memory is stored at a molecular level... Starting with a super simple system (the snail) and looking at how a chemical alters that system, it's not impossible to see how this research might have some value in understanding how memory is processed and stored. There are similarities, even if a snail looks nothing like a human.

    3. Re:Science has come so far. by Beryllium+Sphere(tm) · · Score: 2, Informative

      Biological mechanisms get reused all the time(*). It's plausible enough to be worth investigating that at least some of human memory storage uses mechanisms related to what simpler ancestors used.

      (*) The API for temperature control, for example, got reused across the transition from cold-blooded to warm-blooded. Get a lizard sick, and it spends more time basking so as to give itself a fever. Give it aspirin, and it goes back in the shade.

  6. Surprising by camperdave · · Score: 4, Funny

    Surprising. I would have thought that a story about snails on speed would have a "Look at that S-Car Go" comment by now.

    --
    When our name is on the back of your car, we're behind you all the way!
  7. Another framework language by Captain+Spam · · Score: 2, Funny

    Guys, seriously, the cadence worked for Ruby on Rails, and the silly reference might have worked for Python on Planes if they went through with it, but you're going to have to come up with a better name than Snails on Methamphetamine if you ever want to make COBOL a "cool" programming language.

    --
    Demanding constant attention will only lead to attention.
  8. Re:Too much credit by Darth+Hamsy · · Score: 5, Funny

    Oh, the irony.

  9. Re:New land speed record for snails by Anonymous Coward · · Score: 3, Informative

    Because meth totally gives you the munchies...

  10. Re:NEWS FLASH: Meth Improves Your Memory! by canajin56 · · Score: 3, Interesting

    What? They'll never sell meth OTC, it's addiction potential is too high. And extract byproducts? Meth isn't a blend of a lot of chemicals, like say, an herbal product, it's a chemical. A single one. You can't extract juts the good parts. But, it's not unreasonable to imagine that, for severe memory problems, Meth might eventually get approved. It's already approved and prescribed for ADD, plus used off-label for narcolepsy and depression. Even if not approved for memory, a doctor might still prescribe it off-label for such a purpose. Just remember, for lots of the "designer" drugs like Meth, GHB, Ecstacy, etc. the recreational dose is much higher than the therapeutic dose. So, being prescribed it doesn't mean you go around tweaking on Meth all the time. The doses are low, and they don't let you fill the script all at once, because you COULD purify it into higher doses.

    The only way this could ever end up as something OTC would be if they figure out why, and design a new drug with the same memory enhancing effect, which by a stroke of luck has no serious side effects, isn't (too) addictive, and also evades the moral police by not having a euphoric or inebriating effect. Then it has to be tested for a few decades to PROVE it's totally harmless, then it MIGHT get approved for use without a prescription. (Of course, if they find this similar chemical in a plant, you can sell it as "herbal" straight away, with zero testing or oversight, since it's considered neither a food nor a drug, and the FDA has no jurisdiction).

    --
    ASCII stupid question, get a stupid ANSI
  11. someone call Jon Kovalic by nerdonamotorcycle · · Score: 2, Interesting

    "Snails on Speed" is a card in the game Munchkin. Life imitates art.

  12. Re:Not surprised by vlm · · Score: 3, Insightful

    I think it would take someone who is quite familiar with drugs to ask a question like "What happens when you put a snail on speed".

    What's your judgment of the mental state of someone whom asks:

    What happens if "I watched a snail crawl along the edge of a straight razor. That's my dream; that's my nightmare. Crawling, slithering, along the edge of a straight razor... and surviving. ", on speed.

    --
    "Science flies us to the moon. Religion flies us into buildings." - Victor Stenger
  13. Re:NEWS FLASH: Meth Improves Your Memory! by MachDelta · · Score: 5, Interesting

    Er, Focalin isn't chemically different than Ritalin - they're both C14-H19-NO2. The difference between the two, apparently, is that Focalin contains only one stereoisomer of the compound and Ritalin contains both. As a (gross) example my bio prof once used, if you had two bags full of severed hands, Ritalin would be the bag of left and right hands but Focalin would only contain left hands. They're all the same compound (hands), but some of them are mirror images of the others (left vs right).

    An interesting aside is that the body commonly treats steroisomers very differently. A good example of this would be Thalidomide, which was commonly prescribed to pregnant women in the 50's: One isomer of Thalidomide is a sedative (was prescribed for morning sickness), but the other isomer wreaked all kinds of havoc on the fetus and caused birth defects. Since the body freely metabolizes one form from the other (ie: even given a pure dose of L-Thalidomide, the body would convert some of it to R-Thalidomide), the drug is no longer used. This all varies by compound though. In some cases, steroisomers have different effects, in some cases they have the same (or similar) effect. And sometimes one isomer of a compound is active and the other inert - penicillin is an example of that.
    Biochemistry is crazy stuff. :)

  14. Re:NEWS FLASH: Meth Improves Your Memory! by Creepy · · Score: 2, Interesting

    With the destructive effects that I've seen from meth abusers at my rental property (out of 15 renters in the past 10 years, two have self-destructed into meth abuse), I'm surprised it's still prescribed at all. I would think Modifinil would heavily replace it in that role for almost all of the roles it plays (or Adrafinil, though that hasn't been approved in the US). It mainly hits the same receptors as meth, but is not highly addictive and works on some of the same receptors. It has been petitioned to be legalized OTC (over-the-counter), but I don't know where that is at - I imagine that would be a cash cow for the creator, as I believe it was invented in the mid-1990s (the parent, Adrafinil was 1970s, so I'm not sure the state of any patents). There are some known severe side effects, but as far as I can tell they are rare.

    I'd be curious to see a meth'd up snail and a modifinil snail side by side...

  15. The Link by TubeSteak · · Score: 2, Informative

    TFA screwed up the link to the original journal article

    http://jeb.biologists.org/cgi/content/full/213/12/i

    --
    [Fuck Beta]
    o0t!
  16. Different conclusion... by bynary · · Score: 2, Interesting

    So, they trained snails to stop using built-in survival mechanisms and then gave them drugs that prevented the snails from going back into survival mode. Seems to me like they're not improving memory but are instead prohibiting instinct.

    --
    http://www.bynarystudio.com
  17. Re:Grandma on Meth by couchslug · · Score: 2, Interesting

    Speed, if one doesn't grow to fond of it, is actually quite nice. It is easy, however, to grow too fond of it.
    An appropriate solution would be to invent friendlier speed for appropriate speedful uses.
    (Aircrew "go" pills come to mind as an ethical use of speed.)

    --
    "This post is an artistic work of fiction and falsehood. Only a fool would take anything posted here as fact."
  18. Re:Too much credit by Shatrat · · Score: 3, Insightful

    I see what you did they're...

    --
    09 F9 11 02 9D 74 E3 5B D8 41 56 C5 63 56 88 C0