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Studies Prove BPA Can Cross Placenta To Fetuses

Totes McGotes writes "From canned food to plastic bottles, Bisphenol-A seems to be cropping up everywhere, and now two new studies show that BPA freely crosses the placenta from pregnant mother to fetus. Plus, the research found that chemical transformations occur in the fetus allowing inactive BPA to be converted to the active form."

48 of 234 comments (clear)

  1. Aaaand... by Anonymous Coward · · Score: 2, Insightful

    ...what is this Bisphenol-A and why should I care?

    1. Re:Aaaand... by KevinKnSC · · Score: 4, Funny

      ...he says, taking a long drink from his plastic water bottle.

    2. Re:Aaaand... by ecklesweb · · Score: 2, Informative

      It's a chemical used in many crystal-clear hard plastics. Like water bottles and baby bottles. Don't remember what it does to you - rots your brain or something.

    3. Re:Aaaand... by GungaDan · · Score: 2, Informative

      It feminizes, IIRC.

      --
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    4. Re:Aaaand... by 0100010001010011 · · Score: 2, Funny

      Faaaabulous.

    5. Re:Aaaand... by Shakrai · · Score: 2, Funny

      It feminizes, IIRC.

      That must explain why the current crop of political leaders consists of Chickenhawks on the right and pussies on the left ;)

      I can see the bumper sticker now: Ban plastic bottles! It's cheaper than injecting testosterone into our politicians.

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    6. Re:Aaaand... by Bakkster · · Score: 4, Informative

      Oh, they're all bad.

      Say what now? Nylon? Polyethylene? Nothing bad about them at all.

      As a rule, it's usually the additives and trace chemicals from production that cause problems. All plastics are large chain molecules (and thus not absorbed by the body) and most are quite stable and do not break into monamers that could very easily (which is why most plastics are not biodegradable, and the very reason they are used).

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    7. Re:Aaaand... by toddles666 · · Score: 2, Funny

      Symantec??? Those bastards!

    8. Re:Aaaand... by timmarhy · · Score: 2, Insightful

      The only waste management we need right now is disposal of kdawson's shit stories.

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  2. Great description by sanosuke001 · · Score: 3, Funny
    I love it when the description actually explains why something it good or bad.

    BPA! It cures cancer! Now it can cure your unborn fetus' cancer, too!

    --
    -SaNo
    1. Re:Great description by camperdave · · Score: 5, Informative

      Bisphenol A is a component in polycarbonate plastics, used to make stuff like baby and water bottles, sports equipment, medical and dental devices, dental fillings and sealants, eyeglass lenses, CDs and DVDs, and household electronics. It is also used in thermal and carbonless paper, and as a protective coating on the inside of tin cans. BPA has been linked to obesity and many cancers, and worst of all (dumm, dumm, DAHHHH) adult male sexual dysfunction.

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    2. Re:Great description by TooMuchToDo · · Score: 2, Funny

      Let me be the first to say, "Oh we're so fucked"

    3. Re:Great description by Urkki · · Score: 2, Insightful

      I love it when the description actually explains why something it good or bad.

      No! That's bad when that happens! The ability to comment and moderate are meant for us to demonstrate our superior intellectual capabilities by correcting the glaring factual errors and omissions of TFS and TFA. No, /. depends on bad summaries and articles.

    4. Re:Great description by bzipitidoo · · Score: 2, Informative

      No, it is number 3 (and 7) plastic that may contain BPA. 7 just because it's the category for everything else, but 3 especially. I have not seen any number 3 plastic lately.

      --
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    5. Re:Great description by dacarr · · Score: 3, Informative

      Not quite. Type 2 is HDPE, which according to Wikipedia, does not use BPA. Same with types 1, 4, 5, and 6 - PETE, LDPE, Polypropylene, and Polystyrene, respectively. 3 (PVC) and some 7 (Other, particularly polycarbonate and epoxy) use them.

      --
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  3. Effect of other additives? by Pigeon451 · · Score: 3, Insightful

    So now that companies have stopped using BPA, what other additives should we investigate? Plastics still contain various chemicals that define the type of plastic...

    I've moved to using glass for food storage. Although heavier, it's chemically safer since it's non-porous, and much easier to clean.

    1. Re:Effect of other additives? by exhilaration · · Score: 2, Interesting
      So now that companies have stopped using BPA...

      I'm pretty sure that canned food companies haven't stopped using it .

    2. Re:Effect of other additives? by happy_place · · Score: 4, Funny

      How dare you suggest we use glass, you insensitive clod! My kids and I have trouble with glass, or should I say Glass Shard Contamination, as they tend to break and send shards of glass into the flesh opening blood-letting wounds... though once upon a time blood-letting was considered a form of medical treatment...

      --
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  4. Enough with the "Proof" by fm6 · · Score: 3, Insightful

    Studies don't "prove" anything. All they do is add a little weight to one side of an argument or another. Exactly how much weight depends on what was studied, how it relates to existing science, the methodology of the study, etc., etc., etc.

    This study seems to add a little evidence to the belief that BPA is dangerous, of which there's already a lot. But only scientifically illiterate journalists and pundits (and, unfortunately, not a few opinionated doctors) look a single study and jump to big conclusion. You really need to look at the whole body of research.s

    1. Re:Enough with the "Proof" by thePig · · Score: 4, Informative

      There has been quite a bit of scientific literature regarding BPA - see the links from Wikipedia.

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    2. Re:Enough with the "Proof" by fm6 · · Score: 2, Insightful

      Dude, did you read even a single word of what I said? If you had, you'd know I wasn't defending BPA.

  5. The question is, how bad is BPA Really? by Low+Ranked+Craig · · Score: 2, Interesting

    Apparently we don't really know:

    The JAMA study measured urinary levels of BPA in 1455 adults aged 18-74 years, in relation to 8 conditions: arthritis, cancer, heart disease, diabetes, liver disease, respiratory disease (eg asthma, bronchitis, emphysema), stroke, thyroid disease. Higher BPA concentrations were found only in association with heart disease, diabetes and liver damage. This is a preliminary study, and “association” is not proof of causation but it does give grounds for concern. Bottom line: The significance, if any, of high urinary levels of BPA is not yet known, but long-term studies are certainly needed.

    http://envirolaw.com/how-dangerous-is-bpa/

    Personally I think it's a bad idea to cook food in plastic containers, or store things in plastic that can act as a solvent. The fact that you can taste the plastic container in the food is something I find disturbing and we primarily use glass and stainless, if only for that issue.

    --
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    1. Re:The question is, how bad is BPA Really? by MobyDisk · · Score: 2, Insightful

      The fact that you can taste the plastic container in the food

      This has always baffled me. As a kid I remember the plasticy taste from our plastic drink cups. It was especially noticeable if it was a closed container. You don't need a scientist to tell you it is leeching into the water when you can taste it. I don't understand why that didn't make people think "wait... it tastes like plastic... doesn't that mean that there is plastic leeching in the water? Is this possibly bad for me?"

  6. And to think, all that time... by seanonymous · · Score: 5, Funny

    it was your cup that was poisoned. They were both poisoned. I spent the last few years building up an immunity to BPA.

  7. Re:The endocrine disruptor scam by spaanoft · · Score: 2, Interesting

    I read somewhere that BPA does delay the onset of puberty... but only in boys, and that it speeds it up in girls. I was under the impression that this was happening, but then again I'm nowhere near that field of work so I could be completely wrong.

  8. Bisphenol-A by Anon-Admin · · Score: 2, Informative

    After a little digging I find that it is suspected in everything from breast cancer to obesity in children. It has been suspected as being bad sense the 1930's but there is no direct link to it causing any notable issues.

    So in 80+ years of research the best they can come up with is "There may be an issue with Bisphenol-A"

    It also seems to me that in 3 generations we would have seen a difference or at a minimum science should be able to say "It causes XXX"

    1. Re:Bisphenol-A by capnchicken · · Score: 2, Interesting

      I remember awhile back that there was a study that found that only drinking diet pop still affected a person's obesity, even though it did not contain any calories. http://www.webmd.com/diet/news/20050613/drink-more-diet-soda-gain-more-weight .

      I'm not saying that there is solid correlation here, I'm fine with the opinion that people who drink diet pop are probably the people making the worst food choices anyway. But what if it's not just the sugar, but the propensity to drink pop from cans with BPA and continue to drink them.

      I'd be interested to see European BPA levels contrasted to American BPA levels. What if it's not just caloric intake that is making America so fat, maybe it's our increasing exposure to this, along with calories. There is an obvious increase in childhood obesity and diabetes, what if on top of bad food and poor exercise, it's our increased exposure to this, pre-cradle to grave, that is accelerating our poor health?

      --
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    2. Re:Bisphenol-A by ShadowRangerRIT · · Score: 3, Informative

      Actually, while in no way implicating BPA, in the average age of puberty has been dropping in Western countries for the past 170 years (since the 1840s according to the Wikipedia article). The disparity seems to correlate at least in part, to industrialization; the shift started later in Japan (1945), but progressed more rapidly (dropping by 11 months per decade, instead of 4 months per decade in Europe). In 1840, the average age of first menstruation was 17, in France, 15.3. Nowadays, either age would be considered quite late; typical onset of menstruation is now around age 11.75 worldwide; 12.5 in the U.S.

      Clearly, BPA isn't responsible for the entire historical shift (what with BPA containing plastics only becoming common in the last 50 years or so); changes in diet (particularly the reduction in malnourishment levels) and activity levels (hunter gatherer groups tend to have an onset later than their diet would otherwise allow for) are responsible for some of the difference. But the increased exposure to all sorts of hormone mimicking chemicals (such as BPA) was likely responsible for some of the shift as well. The question is whether BPA is unusually damaging, whether it is possible to remove BPA and other hormone mimicking chemicals from our products and the environment without affecting us negatively in other ways, etc.

      Unlike the realm of medicine, where the scientific method has been applied for to evaluate treatments more and more often in recent decades, the chemical industry remains largely untested and unregulated. People were painting their homes with lead paint and burning leaded gas in their cars and it took decades for studies to make the link to retardation and poor impulse control. For something like BPA, where the negative effects seem to be longer term and less severe than that of lead poisoning, it's not at all surprising that no one has investigated it until recently.

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    3. Re:Bisphenol-A by ShadowRangerRIT · · Score: 3, Interesting

      That's entirely possible. Nothing in my statement directly implicates BPA, yet I'm skeptical that we can add chemicals to our diets that simulate our own sex hormones without affecting the processes those hormones regulate. Whether these effects are dangerous isn't something I know, but I would like to see rigorous studies done. Unfortunately, with chemicals like BPA, we seem to prefer introducing them to everyone's diet in an uncontrolled fashion before bothering to check if the chemicals are safe.

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    4. Re:Bisphenol-A by MobyDisk · · Score: 2, Informative

      So in 80+ years of research the best they can come up with is "There may be an issue with Bisphenol-A"

      Why is that not enough? Do you want them to force feed the stuff to a bunch of people for 30 years and compare them to the general population? Unfortunately, that is just about the only way to know for sure. Will you volunteer to be one of the people in that study? And when it is done, promise not to sue them for turning you into an obese breast-cancer infected human with no reproductive system left.

      BPA is a leeches into your body at low levels over your entire lifetime. It is really hard to tell what that does. It's easy to give someone a 500% overdose and say "look, it killed them!" but how do you definitely determine what it does when nearly everyone is ingesting it, and over a very long period of time? These are called lifelong studies, and the variables are darned tough to control. The fact that there is any correlation at all is enough to say "stop putting this into your body now." Especially since the stuff that leeches BPA is just a cheaper way to manufacture the bottles. Pretty soon, nobody will remember those old stinky smelly bottles that gave your food & water a plastic taste. And we will never kno how much better off we are. I'm fine with that.

    5. Re:Bisphenol-A by evilviper · · Score: 2, Informative

      It has been suspected as being bad sense the 1930's but there is no direct link to it causing any notable issues.

      "The first evidence of the estrogenicity of bisphenol A came from experiments on rats conducted in the 1930s, but it was not until 1997 that adverse effects of low-dose exposure on laboratory animals were first reported."

      It also seems to me that in 3 generations we would have seen a difference or at a minimum science should be able to say "It causes XXX"

      I've got one:

      "Bisphenol-A causes you to develop smaller genitals."

      Also, how about: "Perinatal Exposure to Low Doses of Bisphenol A Affects Body Weight,
      Patterns of Estrous Cyclicity, and Plasma LH Levels" http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1240370&blobtype=pdf

      Any material in contact with food that has such a confirmed, physical affect should be eliminated, nothing else needed. If it was some form of medicine, fine, it has side effects. I don't want my food, or it's packaging to have medical side effects.

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  9. Sort of by Benfea · · Score: 4, Informative

    It acts like female hormones once it gets inside the human body. Not good for adults, but really bad for babies.

    1. Re:Sort of by Yvan256 · · Score: 2, Funny

      I guess Lois Griffin must have used a lot of BPA products while she was pregnant with Stewie.

    2. Re:Sort of by hairyfeet · · Score: 2, Insightful

      It has got to be something because if you have been anywhere near a Junior High lately you know something ain't right. I was loading my groceries at a store next to our local JHS when they got out, and all I could think is "How in the fuck is anybody supposed to tell what is jailbait anymore? Hell these kids are 13 going on 24!". I doubt very seriously even the bouncers at the bar would have thought twice if one of them showed a fake ID. It is just nuts!

      I don't know if it is the BPA in TFA, but we need to seriously be doing blood tests on these kids, because something screwy is going on. All the boys look like little kids and all the girls look like they are in their 3rd year of college. When I was a kid in the 70s it was the boys that started bulking up and getting hair while the girls were 9 times out of 10 flat as a pancake until they hit mid teens, now it seems just the opposite.

      so I don't know if it is BPA, hormones in the meat, what it is, but some serious testing needs to be going down, because little bitty girls shouldn't have C cups and J-Lo butts! All I can say is I'm glad I've got two boys, because if I was those girl's fathers I'd be crazy with worry.

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  10. Re:Freeeeee Markeeeeeeeeeet! by Applekid · · Score: 4, Insightful

    Actually, it is fixing the issue. Practically overnight an industry of BPA-free containers sprang up to service those people who wished to avoid exposure to the chemical. Media and research exists in a free market, so, it's not like we wouldn't have known any link.

    Those that don't care (as in, not caring about their health, not caring since they're using the container to store stuff they don't intend to drink, etc) could still buy it and the prices the market will bare.

    There's a lot of stuff the Free Market can't fix. This isn't one of them.

    --
    More Twoson than Cupertino
  11. Re:Freeeeee Markeeeeeeeeeet! by ShadowRangerRIT · · Score: 5, Insightful

    Assuming they are properly labeled. Unfortunately, the free market only works in a 100% informed populace that can weigh the costs and benefits of any product and have the option to choose. And the fairy tale land of perfectly informed people hasn't yet been made real. Clearly a failure of the free market and government regulation!

    While BPA has alternatives, it's not always 100% clear. Many metal cans and bottles use a plastic lining that happens to contain BPA. Many "glass" products are actually layers of glass and plastic, or just plastic. With no labeling requirements on products composed of mixed materials, I couldn't make informed decisions even if I wanted to.

    Finally, not related to BPA (where alternatives exist if you're willing to look hard enough for them), sometimes the free market fails to provide an alternative. I was trying to find beef stock the other day to make Swedish Meatballs. I generally prefer to avoid MSG and corn syrup in my food products. Of the ~8-10 different varieties of beef stock on the shelf at my local supermarket, all but one of them had MSG (and in large quantities) and a majority (forget the exact number) featured corn syrup (and yes, the only one without MSG had corn syrup). I ended up going with the MSG-free variety (the sodium content was roughly 1/8 that of the standard beef stock from any other brand, and 1/4 the sodium in the "low sodium" varieties), but the free market wouldn't let me avoid corn syrup as well. Nor for that matter do I know if the can itself had a lining containing BPA; even if I wanted to avoid BPA I had no way of making that decision.

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  12. Re:Freeeeee Markeeeeeeeeeet! by fuzzyfuzzyfungus · · Score: 3, Insightful

    Unfortunately, the industry of "BPA free" products sprang up at pretty much exactly the same time that the industry of BPA free products did. It turns out that printing new labels is much easier than actually reformulating your products.

    Also, the "Contains BPA; but nobody except professional toxicologists studying the subject and hardcore supply chain wonks knows that" industries have been largely unaffected.

    Pretty much as theory would predict, the areas closest to ideal markets with zero barriers to entry and equally informed participants achieved something close to a free market solution. The areas that deviated from those assumptions, whether by fraud, subterfuge, imperfect information, or existence of externalities did not.

  13. Better Article by BJ_Covert_Action · · Score: 2, Informative

    For those of you that don't want to dig through the links in the summary blog, here is a more in-depth discussion of the papers.

  14. Re:Freeeeee Markeeeeeeeeeet! by BJ_Covert_Action · · Score: 2, Insightful

    Except for all the people who will continue to use these products because they didn't hear.

    So, we're supposed to craft a society to pander to those who are unwilling or incapable of doing their own research? Yeah, that should work out well....

  15. Re:The endocrine disruptor scam by mcgrew · · Score: 3, Informative

    According to Wikipedia you remember it wrong. And it wasn't the '90s, it was two years ago.

    In 2007, a consensus statement by 38 experts on bisphenol A concluded that average levels in people are above those that cause harm to many animals in laboratory experiments.[28] A panel convened by the U.S. National Institutes of Health determined that there was "some concern" about BPA's effects on fetal and infant brain development and behavior.[10] A 2008 report by the U.S. National Toxicology Program (NTP) later agreed with the panel, expressing "some concern for effects on the brain, behavior, and prostate gland in fetuses, infants, and children at current human exposures to bisphenol A," and "minimal concern for effects on the mammary gland and an earlier age for puberty for females in fetuses, infants, and children at current human exposures to bisphenol A." The NTP had "negligible concern that exposure of pregnant women to bisphenol A will result in fetal or neonatal mortality, birth defects, or reduced birth weight and growth in their offspring."[29]

    Also, later in the wiki article it says there's a link between BPA and both obesity and drug abuse.

    Disruption of the dopaminergic system
    A 2005 review concluded that prenatal and neonatal exposure to BPA in mice can potentiate the central dopaminergic systems, resulting in the supersensitivity to the drugs-of-abuse-induced reward effects and hyperlocomotion.[47]

    A 2008 review has concluded that BPA, mimic estrogenic activity and impact various dopaminergic processes to enhance mesolimbic dopamine activity resulting in hyperactivity, attention deficits, and a heightened sensitivity to drugs of abuse.[48]

    A 2009 study on rats has concluded that prenatal and neonatal exposure to low-dose BPA causes deficits in development at dorsolateral striatum via altering the function of dopaminergic receptors.[49] Another 2009 study has found associated changes in the dopaminergic system.[45]

  16. Re:Freeeeee Markeeeeeeeeeet! by jameskojiro · · Score: 3, Insightful

    We are simply "selecting" for people who stay well informed and actually have a decent IQ. We need to compensate for all dumbasses we are keeping alive despite their own unintentional efforts to put themselves out of the gene pool.

    --
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  17. Re:Freeeeee Markeeeeeeeeeet! by Joce640k · · Score: 3, Insightful

    The opposite of Idiocracy? We definitely need more products like this!

    Sterilize the stupid, kill off the uneducated, yay!

    --
    No sig today...
  18. Timeframes by PIPBoy3000 · · Score: 2, Informative

    Science is pretty good at detecting problems that kill you instantly. In this case, it would be a correlation between BPA exposure while pregnant and breast cancer your children get forty years later. It's difficult to make studies that prove this firmly.

  19. Studies can prove things by pavon · · Score: 5, Insightful

    The article didn't say that the study proved that BPA is dangerous. It said that they proved that BPA can cross the placenta. All it takes to prove that something possible is to record a single incident of it occurring. That is definitely within the realm of what a single study can do, and assuming that these studies were performed correctly, that is exactly what they did. There are a lot of things that cannot be conclusively proven with a single piece of evidence, but the use of the word in this headline here is perfectly legitimate.

    1. Re:Studies can prove things by fm6 · · Score: 3, Insightful

      The article didn't say that the study proved that BPA is dangerous.

      True. But the headline did. Does rather (look at the caption line of your current window)

      It said that they proved that BPA can cross the placenta.

      No, it said researchers "found" this to be the case in experiments with pregnant rats. I'm not just quibbling when I refuse to use the P word here. This is evidence that BPA crosses human placentas, and anybody who cares about neonatal health should certainly pay attention. But it's just not the same as proof. Another researcher might do another study that confirms or refutes this one. That wouldn't be proof either, just more evidence. And any of the above studies might get torn down if something finds fault with their methodology — which happens a lot in science, especially medical science.

      Science isn't about proof. It's about accumulating evidence that backs up or tears down whatever theory or model happens to be under examination. This is inconvenient if you want to write pat little headlines, but it's the main reason science is more effective at advancing human knowledge than religion.

  20. Re:so? by Mr.+Slippery · · Score: 2, Insightful

    If something were really, really bad for you, the evidence would be overwhelming.

    I'm sure your grandfather's doctor said the same thing to him in the 1950s about cigarette smoking. "Bad for you? Nonsense, we'd have overwhelming evidence by now. Have a Camel, they're good for you!"

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  21. Re:More Women by losfromla · · Score: 2, Funny

    hmm. That on the off-chance that you reproduce (you are a slashdotter/geek/asexual), your sons will be female-ish. Unless you are seriously perverted this will not bring you or your androgynous children any joy. Female-ish, is not female, it is just, not-very-male.

    --
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  22. Does it though? by snowwrestler · · Score: 4, Informative

    BPA as a chemical was discovered in the 19th century and it was investigated as a synthetic estrogen in the 1930s. However, it was never pursued as a production estrogen replacement (unlike DES). The question is, why not? Try to find an answer online--it's very difficult.

    My understanding is that while it appeared to act like estrogen in the test tube, it turned out to have very little measurable estrogen-like effect in humans. My understanding is based on reading I did on BPA several years ago, but I have misplaced the citations. If anyone has a link to a detailed history of the pharma research involving BPA in the early 20th century, I'd be interested to read it. The Wikipedia article, for instance, is pretty much silent on anything involving BPA before a few years ago.

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