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Largest Genome Ever

sciencehabit writes "A rare Japanese flower named Paris japonica sports an astonishing 149 billion base pairs, making it 50 times the size of a human genome — and the largest genome ever found. The genome would be taller than Big Ben if stretched out end to end. The researchers warn however that big genomes tend to be a liability: plants with lots of DNA have more trouble tolerating pollution and extreme climatic extinctions—and they grow more slowly than plants with less DNA, because it takes so long to replicate their genome."

32 of 189 comments (clear)

  1. Picture by Glonoinha · · Score: 5, Funny

    Since the article was light on visuals, I found a picture of the largest genome ever.

    --
    Glonoinha the MebiByte Slayer
  2. Obviously: by Anonymous Coward · · Score: 2, Funny

    "Does ist need a Multipass...?"

  3. Thanks for the warning. by Anonymous Coward · · Score: 2, Funny

    The researchers warn however that big genomes tend to be a liability: plants with lots of DNA have more trouble tolerating pollution and extreme climatic extinctions—and they grow more slowly than plants with less DNA, because it takes so long to replicate their genome.

    I'm glad they warned me. I was considering enlarging my genome, but now that I know the dangers I guess I'll pass.

  4. Largest Genome ever by cappp · · Score: 4, Funny

    My girlfriend always said it's not the size of the genome that counts, its what you do with it.

    1. Re:Largest Genome ever by frank_adrian314159 · · Score: 4, Funny

      Yeah, they always say that if you have a small genome.

      --
      That is all.
  5. Actually ... by niclas.l · · Score: 4, Informative

    Big Ben is, technically, the nick-name of the Great Bell inside the clock tower. That bell is only slightly taller than 2 meters.

    1. Re:Actually ... by nedlohs · · Score: 4, Informative

      It's a nickname, there is no "technically".

      It is commonly used to refer to the bell, or to the clock, or to the clock tower.

  6. Re:Can atheists refute one simple fact? by norppalaho · · Score: 5, Funny

    Please to be fucking off of my internet.

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    One of the coolest sites, ever: zombo.com
  7. Re:Can atheists refute one simple fact? by Delarth799 · · Score: 5, Informative

    Everyone on the internet who has read or come near your post is now dumber because of it. I award you no points, and may Al Gore have mercy on your soul

  8. So lots of things. by jd · · Score: 4, Interesting

    Well, a large genome generally means lots of redundancy. Lots of redundancy is theorized to mean high resistance to radiation. This plant should, therefore, be highly resistant. That is potentially quite useful knowledge. Back in the days when people looked to hydroponics and Biosphere 2 as a way of getting oxygen into an artificial environment, they forgot to take into consideration that most plantlife won't cope with the radiation on, say, Mars. In order to be able to get a livable environment for humans, you must first create a livable environment for the plants needed. Obvious solution - use rad-resistant plants as part of an initial program for building up the environment.

    Once you've got an artificial environment that is biologically stable and sustaining good O:CO2 ratios for plantlife, you can look to advancing that environment. I'd suggest having a two layer dome, with the gap between the inner dome and outer dome flooded at as high a pressure as the domes can take something that'll filter the radiation. By having an organic system that can cope, you can take your time getting it right. Regardless of what is actually done, these plants will provide a rich topsoil that will be valuable to the plants that are actually needed by humans.

    --
    It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
    1. Re:So lots of things. by nbauman · · Score: 4, Interesting

      Well, a large genome generally means lots of redundancy. Lots of redundancy is theorized to mean high resistance to radiation.

      Another reason why plants have large genomes is that they tend to duplicate their genomes. One theory is that it makes speciation easier.

      Mind you, it's not as if the designer said, "I'll duplicate plant genomes to make it easier for them to separate into species." They just duplicate and it works out well.

      Apparently plants can double their genomes without the disasterous consequences that it has in animal cells. Animal cells don't double their entire genome unless they're really messed up, like in cancer, and then they're swiftly disposed of.

    2. Re:So lots of things. by Anonymous Coward · · Score: 2, Informative

      I have a fair bit of experience with these genome thingees and it being saturday night I have been drinking some complex carbohydrates mixed with alcohol so the activation energy for posting to slashdot has been reduced (normally most people alive would have something better to do- i know I do). Now, plant genomes expand for two reasons 1) polyploidy events - where the genome is oops accidently doubled (soybean), or 2) massive transposon expansion where small bits are copied many times to give a big genome (eg maize). It sounds like P. japonica is of the #2 variety, ie a small genome of a flowering plant that as been expanded over time by transposons and lost its ability to prune them back out again. So to answer the parents question: It is unlikely to prove radiation resistant as most transposon expanded genomes still only maintain a single copy (x2 for a diploid) of each gene, so a vital function is easily disrupted by radiation induced mutations. If however, P. japonica was massively polyploid, then perhaps it would offer so additional radiation protection- but as the polyploid state, is for most sexually reproducing plants, a temporary state, it could very likely collapse back down into a non-radition protected species quite quickly over time.

  9. Probably multiploid by morty_vikka · · Score: 4, Interesting

    Not that I have read TFA, but this is probably another plant with multiple copies of each chomosome. In which case it's not really a newsflash; this is the case for many plants. Sugar cane and many other monocots have extremely multiploid genomes.

  10. think i saw this before... by Ubergrendle · · Score: 4, Funny

    So does this plant run around asking for a MUL-TI-PASS?

    --
    John Maynard Keynes: "When the facts change, I change my mind. What do you do?"
  11. Re:Can atheists refute one simple fact? by poopdeville · · Score: 2, Interesting

    Anything that had a beginning must have been caused by something else

    You fail right there.

    --
    After all, I am strangely colored.
  12. Thats Big by SuperTechnoNerd · · Score: 3, Funny

    It must be made by Microsoft. Far too many lines of code. :)

  13. Useless comparison by halestock · · Score: 2, Funny

    As tall as Big Ben? That hardly expresses how much data is packed into this genome. I need to know is how many Library of Congresses this genome is in order to fully comprehend the size.

  14. Re:Can atheists refute one simple fact? by bertok · · Score: 3, Informative

    Converted to mathematics, the error in logic if more clear:

    1) You say that for all 'x', there must be an 'x-1'. ("a cause", "antecedent", "precedent", or whatever)

    2) You say that "we atheists" claim that the "first thing" is '1'.

    3) Hence, if there's a '1', there must be a '0'. ("the first thing must be created")

    4) Then, you basically make the unfounded claim that '0' must be 'God'.*

    The problem is that this simply implies that all negative numbers must exist also, (-1, -2, -3, etc...), since there's no reason to stop at 0.

    In other words, there's no reason to stop at "God". God must also have a cause. And the cause of God must also have a cause, etc...

    If you say that "God" is special and has no cause, then (1) was not true, it's actually "for all 'x' except some 'x' there must be an 'x-1'", which is a different rule. Hence, the whole argument is hogwash, since the original rule cannot be true for it to work. That is, if there are exceptions to the rule, then there's no reason for the Universe itself to not be one of those exceptions. This argument, and it's counter-arguments have been known since ancient times, it's not exactly new. You're not exactly surprising any Atheists with a shocking new proof. For crying out loud, there's a 10-page Wikipedia article about it's long history.

    * I assume that you refer specifically to the Abrahamic God that spoke to a barely literate goat herder on the side of a mountain in ancient Palestine, raped some woman who was apparently a virgin despite living with her husband, and then watched his illegitimate son get executed, right? Otherwise you could be speaking of any God. Lets say, Zeus. I like Zeus. He's the kind of womanising, lightning-bolt throwing God I can relate to! Some of his human consorts were even awake when he impregnated them -- what a gentleman! If we're going to start making assumptions that "the cause of the universe" must be a specific God, lets pick a good one!

  15. Re:Can atheists refute one simple fact? by atmurray · · Score: 5, Insightful

    “I contend we are both atheists. I just believe in one fewer god than you do. When you understand why you dismiss all the other possible gods, you will understand why I dismiss yours.”- Stephen F. Roberts

  16. Re:Can atheists refute one simple fact? by Artifakt · · Score: 2, Interesting

    What about Carl Sagan's argument?
    He argued (in 'Cosmos') that if it was necessary to postulate a cause for the universe, it was necessary to postulate a cause for whatever caused the universe, and if it was not necessary to claim there was a cause for "God", it was also not necessary to claim a cause for the universe. But not 15 pages before he made that claim, he discussed the old Steady State theory and how it was succeeded by the Big Bang model. Sagan allowed the steady state to be causeless, since there was no first moment for an infinitely old universe. But if that's true, Dr. Sagan was also arguing that a 'Big Bang' type universe had a special reason for needing a cause that the Steady State version did not. He was claiming that it was sufficient in one case for science to simply say that not everything has to have a cause, but in the other case that science was only specifically able to skip reasoning about the cause of a thing because it did not have an origin. Why then was it fair to allow the steady state to be causeless, but demand that God must have a cause if the current (Big Bang) model must have a cause? Wouldn''t "God" be more like the steady state than the big bang (at least as most religions define God)? Why did Carl Sagan reason from Anything that had a beginning must have been caused by something else to conclude that something that had no beginning didn't need a first cause, and then reject the very same idea not 15 pages later? Why did he treat a question as strictly rhetorical when he in fact had given a straight, non-rhetorical answer to it not 15 pages before?
    So, going by the way the first post was modded and responded to, Carl Sagan was nothing better than a slashtroll who made us all dumber. Personally, I disagreed with him on several points, but thought he was legitimately brilliant and certainly worthy of publication. I guess I should adopt some of your attitudes and burn his books instead.

    Fact: Dozens of distinguished scientists in the 1930s and 40s pointed to the Steady State model as a positive disproof of God, and fought against accepting the Big Bang model because they claimed it was bringing religious superstition back into science. Not one of them was willing to admit after the Big Bang won out by actual evidence that they had been wrong to interpret the science that way. Most of them, when pressed on it, stipulated two things: 1) That even if the Steady State and Big Bang theories were opposite in their predictions in just about every other respect, they were not opposite in their implications about religion, and 2) that the Big Bang would not be a scientific theory unless it shared the common property of disproving the existence of God.

    I see several logical flaws in the initial post. In particular, the claim that an actual infinite cannot exist is highly suspect. A lot of the post is rehashed Augustine, and the debate about Augustine's reasoning has echoed through philosophy for over a millennium now. Some of it borrows from Pascal, but then, most people don't reject Pascal's contributions to probability theory and logic just because there are flaws with "Pascal's Wager". However, the refutations here are just as flawed, if not more-so, and I've seen some brilliant men make the same sort of errors many of you are mocking, in the modern era. If you're not prepared to stoop to Karma mods and dumb one-liners for them, maybe some of you just might want to set yourself a better standard here.

    --
    Who is John Cabal?
  17. Thanks for the warning about big genomes by Anonymous Coward · · Score: 2, Insightful

    The researchers warn however that big genomes tend to be a liability: plants with lots of DNA have more trouble tolerating pollution and extreme climatic extinctions--and they grow more slowly than plants with less DNA, because it takes so long to replicate their genome.

    Thanks for the warning; I'll remember it when designing future plant species.

    - God

  18. congratulations, we've got a new Unit by CAIMLAS · · Score: 2, Funny

    Congratulations, we now have a new unit of measurement to join the myriad:

    * Libraries of Congress
    * Landmasses of Texas
    * States of Massachusetts
    * California Economies
    * Lines of Code
    * Man-Hours
    * Kilobits per second

    Welcome to the fold, Big Bens!

    --
    ~/ssh slashdot.org ssh: connect to host slashdot.org port 22: too many beers
  19. Re:Can atheists refute one simple fact? by nitehawk214 · · Score: 2, Funny

    The answer is simple:w

    Are you typing your slashdot comment with vi?

    --
    I'm a good cook. I'm a fantastic eater. - Steven Brust
  20. Re:Mohammed? Gay? I think not by Eskarel · · Score: 2, Insightful

    I suppose there's also a matter of scale, when you're probably not going to live to see 30, waiting till 25 seems a bit of a stretch.

  21. Re:Can atheists refute one simple fact? by vjoel · · Score: 2, Funny

    The earth was created by god. god was created by a giant frog. the giant frog was created by robotic jesus.

    And all those lies were created by man, in particular, certain individuals who where trying to control the rest of the population.

    You can't fool me, Mr. James. It's frogs all the way down.

    --
    What part of `yes no` don't you understand?
  22. Bloatware... by SpaceAmoeba · · Score: 3, Funny

    Clearly humans are more efficiently coded.

  23. Re:Can atheists refute one simple fact? by ooshna · · Score: 2, Funny

    He didn't give birth to him. He is a mud man duh. Made out of dirt then God gave him CPR. check your bible before you start talking nonsense.

  24. Re:Can atheists refute one simple fact? by Patch86 · · Score: 2, Insightful

    All we can infer from Big Bang theory is that the current state of the observable universe originated from a single point of space some 13.5 billion years ago, and has expanded out from that point ever since.

    It makes no judgement on what the universe looked like immediately before, or it's cause. Possibilities such as a cyclical universe, or the observable universe as part of a greater whole (such as a multiverse), are not ruled out by BB theory (and predicted by some theories, such as M-String theory).

    The possibility of "all of existence" essentially following a Steady State model is still an open one. And unfortunately due to the nature of the observability of the universe, probably impossible to prove conclusively one way or the other.

    IANATheoreticalCosmologist, by the by.

  25. Re:Can atheists refute one simple fact? by vadim_t · · Score: 3, Insightful

    Other people spoke of the other parts of this already, but I thought I'd make a point I rarely see:

    When people speak of religion being the source of morality, it becomes obvious they never actually read the bible. In it, Moses, Abraham and a few other people actually argue with God and get him to change his mind on smiting some people. If they can argue with God on smiting, then they must have a source of morality that's not God, because otherwise whatever God says is the moral thing, and there can't be an argument.

  26. indeed by DrYak · · Score: 2, Insightful

    you joke, but that's indeed the case :
    - were're hot blooded and thermally regulated
    - we live in an environment with a very narrow varability
    (i mean the direct environment next to our skin. When it's cold outdoor, we just put more clothes on, instead of going out naked)

    thus our enzymes have only to work in a very specific range of conditions. Unlike this plant which has to sustain a wide range of variations, and thus needs lots of different genes coding for similar proteins,but each optimised for a slightly different set of conditions to cover the whole range (to be able to carry on a reaction no matter the temperature, plant just picks up the variant which works best at the current temperature. Meanwile, we just set the internal thermostat on 37C, use only the 37C-optimized enzyme, and be done with it)

    --
    "Sufficiently advanced satire is indistinguishable from reality." - [Tips: 1DrYakQDKCQ6y52z6QbnkxHXAocMZJE61o ]
  27. Not under Wikipedia's watch! by zoidran · · Score: 2, Interesting

    Can a biologist confirm the summary/TFA are right? Wikipedia seems to disagree...
    http://en.wikipedia.org/wiki/Genome#Comparison_of_different_genome_sizes
    Which one is trustworthy?

  28. repetitive by kharchenko · · Score: 3, Informative

    Large plant genomes tend to be polyploid (>2 copies of chromosomes) and full of repetitive elements. In other words, the overall complexity is similar to other plants, even though the total size is much larger.