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Scientists Overclock People's Brains

arshadk writes with this excerpt from the BBC about researchers at Oxford University who found that inducing a small current in a subject's parietal lobe boosted their capacity for numerical learning: "The current could not be felt, and had no measurable effect on other brain functions. As it was turned on, the volunteers tried to learn a puzzle which involved substituting numbers for symbols. Those given the current from right to left across the parietal lobe did significantly better when given, compared to those who were given no electrical stimulation. The direction of the current was important — those given stimulation running in the opposite direction, left to right, did markedly worse at these puzzles than those given no current, with their ability matching that of an average six-year-old. The effects were not short-lived, either. When the volunteers whose performance improved was re-tested six months later, the benefits appear to have persisted. There was no wider effect on general maths ability in either group, just on the ability to complete the puzzles learned as the current was applied."

57 of 314 comments (clear)

  1. sweet !! by ckeo · · Score: 5, Funny

    K... I just cut the cord off a lamp... somerone talk me through this O.O

    1. Re:sweet !! by jeffmeden · · Score: 2, Interesting

      Working with AC may be problematic... Are you comfortable only learning something for 1/120th of a second at a time?

    2. Re:sweet !! by ckeo · · Score: 5, Funny

      hmmm... maybe I should just suck on a 9 volt battery while I am studying :/

    3. Re:sweet !! by Yvan256 · · Score: 3, Funny

      Luckily for you there is two flavors available: Duracell and Energizer!

    4. Re:sweet !! by JonahsDad · · Score: 2, Informative

      Was at Oxford, so wouldn't it be 1/100th of a second at a time?

    5. Re:sweet !! by lazarus+corporation · · Score: 5, Informative
      From the first sentence of the summary at the top of the page:

      arshadk writes with this excerpt from the BBC about researchers at Oxford University who found that...

      As an Englishman I may be biased, but I think the BBC counts as a major news company.

    6. Re:sweet !! by Anonymous Coward · · Score: 4, Funny

      How do you know what cat piss tastes like?

    7. Re:sweet !! by Naerymdan · · Score: 2, Funny

      Ever drank cofee?

      --
      Bah.
    8. Re:sweet !! by u17 · · Score: 2, Interesting

      K... I just cut the cord off a lamp... somerone talk me through this O.O

      You need to make sure that you're using a DC, not an AC lamp... TFA said that the direction of the current matters! If it's a DC lamp, make sure you've cut the cord past the rectifier. Then locate the ground and positive wires. Stick the positive in your left eye, making sure not to damage the eyeball, you need to carefully squeeze it in between the eyeball and the eyelid. Might need some good lubricant there. Then stick the ground similarly in your right eye. The eyes the easiest way to reach the brain, seeing as they're just an extension of the organ. With me so far? Great! If you're still alive, try to focus on multiplying big numbers. If either of your eyes pops out due to the effort, make sure to hold the wire terminal in to prevent it from disconnecting. Once you smell burning tissue, it means your result is ready! Now call an ambulance IMMEDIATELY and don't forget to write down your result, your family might need it as proof for the life insurance company that your death wasn't suicide, in fact it was a scientific endeavour. Good luck!

    9. Re:sweet !! by snspdaarf · · Score: 2, Funny

      I am glad he did. It saves the rest of us a lot of effort and embarrassment. Not to mention cat scratches.

      --
      Why, without your clothes, you're naked, Miss Dudley!
    10. Re:sweet !! by Reapman · · Score: 3, Funny

      This reminds me of that time you tried to drill a hole in your head....

    11. Re:sweet !! by Hal_Porter · · Score: 2, Funny

      You're right! I'll look into this and

      --
      echo -e 'global _start\n _start:\n mov eax, 2\n int 80h\n jmp _start' > a.asm; nasm a.asm -f elf; ld a.o -o a;
    12. Re:sweet !! by Ster · · Score: 3, Funny

      This reminds me of that time you tried to drill a hole in your head....

      That would have worked if you hadn't stopped me.

    13. Re:sweet !! by FleaPlus · · Score: 2, Interesting

      K... I just cut the cord off a lamp... somerone talk me through this O.O

      DISCLAIMER: I've run tDCS experiments in an academic setting before. The info provided below is merely for speculative/educational purposes, and if someone fries their brain it's not my fault.

      It's actually surprising how simple the setup for a tDCS experiment is. All you need are some sponge elecrodes, some saline to soak them in, and a way to deliver a constant current (say, 1 mA). Sponge electrodes can be purchased online, or they could potentially be made at home. I'm not sure what size electrode they used in the experiment, but I imagine 2"x2" would work.

      Sponges should be soaked in enough saline to transmit electricity with little resistance (resistance tends to result in uncomfortable heat), but not so wet that water is dripping down. An elastic headband is handy for keeping the sponges in place.

      The device used in lab was a fairly inexpensive (by research/medical standards) iontophoresis drug delivery device, powered by an off-the-shelf 9V battery. I think those are only available to practitioners, but I imagine that all you really need is a simple (ideally battery-powered for safety) current source which can send 1mA through the electrodes. (again, don't have access to the paper, so don't know if 1mA is what they used)

      One sponge would go over one of the parietal cortices, on the back-top-right or back-top-left of the head. The other sponge would go over either the opposite parietal cortex or a "neutral" location like the vertex on top of the head. tDCS has a fairly crude spatial resolution, so one doesn't have to worry about being precisely pinpointed over a particular brain region.

      I'll add in a disclaimer again that the above is quite possibly entirely wrong, and it's quite possible I've made a mistake in my description, I'm not liable, etc. etc.

    14. Re:sweet !! by Elder+Entropist · · Score: 2, Insightful

      But if they're dumber, will they realize it?

  2. Uhhhh.... WHAT? by Monkeedude1212 · · Score: 5, Interesting

    those given stimulation running in the opposite direction, left to right, did markedly worse at these puzzles than those given no current, with their ability matching that of an average six-year-old ... The effects were not short-lived, either. When the volunteers whose performance improved was re-tested six months later, the benefits appear to have persisted.

    What about the other sides, were the negative effects persistant? Did you just create a group of idiots? Is this legal?

    1. Re:Uhhhh.... WHAT? by jeffmeden · · Score: 4, Insightful

      The effect seemed to influence the learning process... IE when the current is applied in the correct direction the learning process takes place very quickly and when in the opposite direction it takes place very slowly. The subjects retested later showed they retained the learned skill, not the *ability* to learn that was afforded by the electrical stimulation.

      Of course, lacking any such mental enhancement my interpretation of this may be totally wrong.

    2. Re:Uhhhh.... WHAT? by heatseeker_around · · Score: 2, Funny

      I was about to ask the same question. This is a huge side effect. "Don't worry, it will not affect any other parts of your brain. You will just be a retard and unable to resolve simple puzzles for at least... we don't know yet. You'll tell us !"

    3. Re:Uhhhh.... WHAT? by Ryanrule · · Score: 2, Funny

      well, is it legal for stupid, ignorant people to have kids?

    4. Re:Uhhhh.... WHAT? by Yvan256 · · Score: 3, Funny

      The english-speaking participants then replied "Wakarimasen"?

    5. Re:Uhhhh.... WHAT? by RockoTDF · · Score: 2, Informative

      I seriously doubt peer reviewers would have let them get away with not reporting persisting performance drops.

      --
      There is more to science than physics!

      www.iomalfunction.blogspot.com
  3. So basically... by DoofusOfDeath · · Score: 2, Insightful

    So basically we're FPGAs?

  4. My old boss used to do this too...no biggie. by Pojut · · Score: 5, Insightful

    Back when I worked as a mechanic, the guy that owned the place and a buddy of his used to bring cars into the shop after hours, snort up a line of blow, and go to town. I once watched them pull a motor out of a Honda Civic in 15 minutes, surgeon style (one guy giving and taking tools/nuts/bolts, one guy using the tools to remove said nuts/bolts).

    No exaggeration. 15 minutes. It transcended bitchin'.

    1. Re:My old boss used to do this too...no biggie. by Anonymous Coward · · Score: 5, Funny

      15 minutes for a Honda Civic? What is so hard about cutting a couple of zip-ties?

    2. Re:My old boss used to do this too...no biggie. by HeckRuler · · Score: 2, Funny

      I'm sorry, could you give that to me as a car analogy?
      er...

    3. Re:My old boss used to do this too...no biggie. by Anonymous Coward · · Score: 3, Informative

      I once watched them pull a motor out of a Honda Civic in 15 minutes, surgeon style (one guy giving and taking tools/nuts/bolts, one guy using the tools to remove said nuts/bolts).

      No exaggeration. 15 minutes. It transcended bitchin'.

      Aside from the illegal drugs in your story, did you ever think that maybe what happens in surgery is just the most efficient method of doing things? When you don't need to fumble for your instruments, you generally can do things more than at 2x the speed thanks to not having to switch your focus from your job.

      If all you remove and install a given engine a few times, you get to the point where you know all the steps and know all the tools that you'll need. Even better if the helper knows the steps too. This is why surgeons work as fast as they do. Practice, practice, practice.

    4. Re:My old boss used to do this too...no biggie. by quacking+duck · · Score: 4, Funny

      Reminds me of a Top Gear episode where they discovered that changing out an engine of a car took less time than a group of women getting ready to go out for the evening.

    5. Re:My old boss used to do this too...no biggie. by shugah · · Score: 3, Informative

      That jeep was specially prepared for that demonstration.

      The "engine/transmission" unit must have a self contained fuel tank, battery, and coolant reservoir (radiator) and some sort of quick release engine mounts. There were no fuel lines and while one guy dropped the radiator in just before the hood went on, he didn't connect up any coolant lines. It was probably a 2-wheel drive jeep, to eliminate connecting the front differential. There must have been some sort of quick disconnect on the drive shaft U-Joint. There also must not be a floor or firewall in the jeep so that the shift linkage and accelerator pedal and throttle linkage could all be left attached to the engine/transmission unit.

      You could see a muffle hanging below the chassis, so the exhaust manifolds and header pipe must have just slid into some sort of receiver pipe (I guess it didn't have to pass CARB or EPA testing). Also unless there must have been some sort of multi-pin electrical harness connector or none of the lights would have been functional. The ignition switch was probably attached to the engine and accessible through the open floor / firewall.

      The Jeep has no brakes; there were no brake lines connected to the "body" unit (where the master cylinder would be). Likewise, steering linkage between body and the front suspension/axel must have had some sort of quick disconnect. Also, no heater, no windshield wipers/washers, no speedometer or guages of any type mounted on the dash (possibly on the engine/transmission unit).

      So given that the Jeeps was specially designed to be taken apart and put back together in under 4 minutes, it is not surprising that team trained for that function were able to do so.

      --
      If you aren't part of the solution, then there is good money to be made prolonging the problem
  5. so many questions by cindyann · · Score: 3, Interesting

    Any observation or correlation to right-brained, i.e. left-handedness?

    How did the subjects perform with a slightly higher current?

    And when they cranked it to 11?

  6. Re:Overclocking? by javelin682 · · Score: 2, Insightful

    you don't get the BSO part, you just get D

  7. Re:Ridiculous by UnknownSoldier · · Score: 2, Informative

    Oblg: You have to break a few eggs to make an omelette.

  8. Love the journal name... by lazlo · · Score: 4, Funny

    The findings are reported in the journal Current Biology.

    Awesome pun.

    --
    Pound! Bang! Bin! Bash! is this a shell script or a Batman comic?
  9. Re:Overclocking? by KingSkippus · · Score: 2, Funny

    You get a Blue Scream of Death.

  10. Re:Ridiculous by Anonymous Coward · · Score: 2, Interesting
  11. Re:you can do this with drugs too by Anonymous Coward · · Score: 2, Insightful

    "stop trying to improve on what you have. just use it, and take care of it" ??? Are you serious?

    I am really glad that nature, science, business, art, linguistics, etc. -- generally disagrees with your harmful advice. Thankfully, we have selfish genes. And these genes take risks. Because risk-taking is the natural path to growth, learning, innovation, etc.

    Life is not an exercise in conservation! Human nature seeks constant improvement. Humans are risk takers, thankfully. You only have one life to live, so don't squander it by being safe.

  12. Re:you can do this with drugs too by Doc+Ruby · · Score: 4, Informative

    Which drugs? Plenty of drugs taken in moderation can be sustained throughout a natural lifespan without damage. Very few drugs, especially those used longer than the last few generations, "burn out neurons" or cause any neuropathy of any kind, at active doses that aren't toxic. Alcohol is an exception. But heroin is not. All drugs temporarily "lower the potential" of neurons or raise them: otherwise they'd have no effect whatsoever. But so does eating too much food (or not enough), or habitual running, or having sex.

    Blanket statements about drugs are rarely meaningful enough to take as useful advice.

    --

    --
    make install -not war

  13. Re:you can do this with drugs too by martas · · Score: 5, Insightful

    you can't improve upon the performance of your brain and your body without longterm tradeoffs

    i hate that kind of defeatist, "nature/god knows best" attitude. everything you have right now is thanks to people who believed they could do better than nature, and they did. yes, you shouldn't do lines of coke to be better at your job, because that is a hack. it doesn't mean we can't make ourselves truly better, without "overclocking" and burning out. a candle that burns twice as bright could burn out twice as fast, or it could simply be a fucking light bulb that lasts 5 years.

  14. Ridiculously Brilliant by HeckRuler · · Score: 4, Insightful

    Well, these people are learning more about the brain BY screwing around with it. How else do you learn things? Unfortunately, we're missing the user's manual.

  15. Oldnews by durrr · · Score: 5, Informative

    This phenomena is quite well studied, and seems to be producing relatively linear effects. It was discovered in the 70's or so. It's refered to as transcranial direct current stimulation and just a few months ago there was a study on visual memory about the same.
    It's not really new and revolutionary, it's just that the previous studies haven't been able to be worded as "OMG BRAINOVERKLOCKING!" and thus haven't generated the same interest.
    http://nextbigfuture.com/2010/08/direct-current-stimulation-more-than.html

    1. Re:Oldnews by RockoTDF · · Score: 3, Insightful

      I know it is well studied, I'm a neuroscientist. What I am saying is that we must not assume that the effects over time are the exact opposite in each direction.

      --
      There is more to science than physics!

      www.iomalfunction.blogspot.com
    2. Re:Oldnews by maxwell+demon · · Score: 2, Insightful

      Indeed, if you increase the current in the better-learning direction too much, the result will not be much better learning, but permanent damage. That's a very non-linear effect.

      --
      The Tao of math: The numbers you can count are not the real numbers.
  16. Re:you can do this with drugs too by corbettw · · Score: 2, Funny

    yes, you shouldn't do lines of coke to be better at your job

    Except, of course, for those rare individuals for whom doing coke is a part of their job. Used car salesmen, comedians, politicians, that sort of thing.

    --
    God invented whiskey so the Irish would not rule the world.
  17. LASIK, high blood pressure, gene therapy... by KingSkippus · · Score: 5, Insightful

    Crud, then, because I and a LOT of my friends have had LASIK surgery to correct my vision. It turns out god gave me bum eyes that focused everything slightly in front of my retina, and that fixed it pretty well with minimal, if any, long-term trade-off.

    My dad had high blood pressure. In spite of efforts to control it through diet and exercise, he foolishly took drugs to control it, thinking that he could improve upon his natural system to regulate it. He died a few years ago of bladder cancer. I'm not sure how exactly that was a long-term tradeoff since the doctors told us they were completely unrelated, but he seemed not to mind the short-term benefit of living a reasonably long time.

    Also, where exactly do we draw the line? I mean, some people run 10 miles or more a day; surely that can't be normal and can be considered a measure to "improve on what you have," and statistically, those people tend to live longer. Do we consider eating certain foods that contain substances shown medically to lead to longer and more healthy lives, or for that matter, avoiding natural foods that contain substances shown medically to be harmful (fat, cholesterol, etc.) to be trying to improve on what we have? Before long, we'll be living in a world where technologies such as gene therapy could prevent or significantly reduce conditions like Down's Syndrome, diabetes, Alzheimer's, etc. Should we avoid those as well?

    I suspect that this study is the first in a long line of research that may lead to exciting new therapies for people who might not be able to learn normally. And yes, if it's shown effective without significant side effects, it might be used much as LASIK is today, a method of improve on what we were given with little to no risk. Personally, I don't see much wrong with that. If you disagree, that's certainly your right, but I would ask that you not judge others, try to impinge on the freedom of others to make informed decisions regarding their own body, or worst of all, try to keep the research from happening that could potentially improve the lives of many people who are not able to function normally in society due to preventable or even curable disabilities.

    Just some food for thought.

    1. Re:LASIK, high blood pressure, gene therapy... by Eevee · · Score: 2, Interesting

      I mean, some people run 10 miles or more a day; surely that can't be normal...

      Actually, humans are evolved for just that--persistence hunting is basically constantly running after an animal until it's too exhausted to get away.

    2. Re:LASIK, high blood pressure, gene therapy... by Quirkz · · Score: 2, Funny

      Avoid chemicals? Like dihydrogen monoxide?

    3. Re:LASIK, high blood pressure, gene therapy... by KingSkippus · · Score: 2

      Actually, I noticed after I posted that there was a weird mix of sarcasm and seriousness, and I thought, "You know, some people are going to interpret that wrong." If I could take it back, I would have worded it a bit differently to make what I was saying consistently clear.

      Oh well, it wasn't really meant to be an editorial masterpiece, it was just a couple of random thoughts trying to convey that saying that people shouldn't try to improve themselves is kind of an overly broad statement, that sometimes there really are no long-term negative effects from doing so, and sometimes there are negative effects, but they are worth the price of whatever improvement you are undergoing, be it natural, chemical, or surgical.

  18. Stupid is as stupid does.. by TiggertheMad · · Score: 2, Funny

    Did you just create a group of idiots?

    pretty sure that people who offered to let scientists run current through their brains as part of a test to see how it affects learning aren't Nobel prize winners to begin with....

    --

    HA! I just wasted some of your bandwidth with a frivolous sig!
  19. Re:Um.. by countertrolling · · Score: 2, Funny

    Put a diode in your electrical socket, and hook yourself up.. Be sure to stream the video on the web.

    --
    For justice, we must go to Don Corleone
  20. Re:Overclocking? by mehrotra.akash · · Score: 3, Funny

    How do you accidently overclock a PC??

  21. Re:you can do this with drugs too by Joe+Snipe · · Score: 4, Insightful

    I like to phrase it like this:

    Drugs are like cheat codes on video games. They can be a lot of fun, and you might see and do things you wouldn't have been able to do otherwise. But then it starts to get boring, and playing without the cheat code starts to feel unsatisfying (or to difficult). Unfortunately you can't switch to a different video game because with drugs it's your life that you're playing.

    --
    Sometimes, life itself is sarcasm...
  22. Re:you can do this with drugs too by Beerdood · · Score: 3, Informative

    I think LSD is a decent example of what you could consider over-clocking. If you take a large amount (like 4 or more hits at once) your brain is in absolute overdrive and can certainly perform some functions better than others. And just like over-clocking a CPU you run the risk of burning out a few circuits and getting flashbacks and tracers later in life. This is the official term, and I've heard a few old hippies that claim to have this from too much use from too much use years ago

    --
    Global warming and other natural disasters are a direct effect of the shrinking number of pirates - Gospel of the FSM
  23. bah! by t2t10 · · Score: 2, Funny

    You should see how quickly people solve puzzles once you start applying current to other parts of their anatomy :-)

  24. You're wrong by canuco · · Score: 2, Funny

    Too bad coffee taste like cat piss,

    I actually tasted both and cat piss is a lot saltier.

    Wait a second, what kind of coffee do you drink?

  25. Associative area by DrYak · · Score: 2, Interesting

    Parietal arae are associative area (they don't directly process sense, they do very high-order associate/combination/processing).

    With lots of broad simplification : By applying a so low current, nothing dirrectly happens in the brain. Only one side gets a slightly more positive potential, the other slightly more negative compared to the normal potential in a "normal" brain. No impulse are caused per se. So no spasms, no feeling, no whatever. But the slighlty altered electric potential can make neurons slightly more likely to fire up a potential on their own. If they get the electrode polarity correctly with regarding to the dominant region, the neurons might be slightly more likely to be a bit more active.

    Again, while over-simplifying : The brain "learns" and "remembers" by selecting the most "used" or "useful" signal paths. More active zone (due to stimulation) = more neurons firing = more "paths" tested = more likely to arrive at a new useful firing sequence. (it's lie-to-childern, but you got the main idea). So stimulating the brain means more neuronnal pathways are tested and ultimately selected. Slowing down brain activity does the countrary.

    Thus by modulating slightly the activity rate of a brain region, we can modulate the "spead of learning" of this peculiar region.
    But doesn't leaves any permanent effect beside having learnt what one has learnt.
    (After the test, activity goes back to normal. Only newer pathways which where positively selected are retained).

    This only improved their learning, pattern recognition, or maybe their "comparative/sorting" abilities.
    While the latter(ordering symbols) is sort of useful for math, this didn't show the subjects could add up the cost of a meal and figure the tip any better than before, let alone learn calculus.

    Well because that's what these associative regions are for. Complex abstract pattern *recognition*. So good for these exercises.
    Calculus could also require also advanced planning which would proceed in a completely different region (parts of the frontal cortex), etc.

    The global mechanisme is known for quite some time, I remember several years ago about magnetic stimulation of the motor cortex slightly helping the first step of learning to play the piano (which is a complicated process in itself, requiring much more than basic motor skills. so the method did only slighly help the first stages).

    Can these type of methods be used to make Matrix-style "download kung-fu knowledge straigh into the brain" training possible ? No.
    But they could be used to give slightly nudges and help speed up some general aspects of a learned skill. (Just the same way a sport practitionner could do balance or coordination exercices to help these aspects in order to perfect her/his craft).

    --
    "Sufficiently advanced satire is indistinguishable from reality." - [Tips: 1DrYakQDKCQ6y52z6QbnkxHXAocMZJE61o ]
  26. Stim Pack has finally been researched at: Academy! by Shompol · · Score: 2, Funny

    Marines double their rate of fire and increase their movement rate for a limited period of time.

    Scientists from Academy report that they have researched Stimpack. The Research lasted 80 time units and required funding of 100 minerals and 100 gas. Scientific community hopes that this discovery will help keep Mutalisks and Zerglings in check.

  27. Re:Overclocking? by steelfood · · Score: 2, Funny

    Cut one of the plugs from the power supply and run a current from right to left through the CPU?

    --
    "If a nation expects to be ignorant and free in a state of civilization, it expects what never was and never will be."
  28. Opposite direction? by wjwlsn · · Score: 2

    So pushing the current from right to left improved mathematical learning, while the opposite direction hindered it. Is there anything that would be improved by the left to right current? Is this whole phenomenon an example of brain lateralization? This little wikipedia excerpt on lateralization of brain function is interesting in this light:

    Linear reasoning and language functions such as grammar and vocabulary often are lateralized to the left hemisphere of the brain. Dyscalculia is a neurological syndrome associated with damage to the left temporo-parietal junction. This syndrome is associated with poor numeric manipulation, poor mental arithmetic skill, and the inability to either understand or apply mathematical concepts.

    In contrast, prosodic language functions, such as intonation and accentuation, often are lateralized to the right hemisphere of the brain. The processing of visual and audiological stimuli, spatial manipulation, facial perception, and artistic ability seem to be functions of the right hemisphere.

    There is some evidence that the right hemisphere is more involved in processing novel situations, while the left hemisphere is most involved when routine or well rehearsed processing is called for.

    --
    Getting tired of Slashdot... moving to Usenet comp.misc for a while.