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Scientists Turn Skin Into Blood

Breakthru writes "In an important breakthrough, scientists at McMaster University have discovered how to make human blood from adult human skin. The discovery, published in the prestigious science journal Nature today, could mean that in the foreseeable future people needing blood for surgery, cancer treatment or treatment of other blood conditions like anemia will be able to have blood created from a patch of their own skin to provide transfusions. Clinical trials could begin as soon as 2012."

25 of 229 comments (clear)

  1. Sunlight? by camperdave · · Score: 5, Funny

    In an important breakthrough, scientists at McMaster University have discovered how to make human blood from adult human skin.

    So not only will it clot, it can tan?

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  2. Just one minor complication. by Anonymous Coward · · Score: 4, Funny

    That whole "walking around with no skin" situation could be a bit of a problem.

    1. Re:Just one minor complication. by 93+Escort+Wagon · · Score: 5, Funny

      That whole "walking around with no skin" situation could be a bit of a problem.

      So you think walking around with no blood is preferable?

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    2. Re:Just one minor complication. by Lucky75 · · Score: 5, Informative

      From what I read in other articles not posted on slashdot, something like a 12x12 cm patch of skin is enough to create enough blood for a transfusion. That's about the same amount removed during normal grafting operations.

      Link

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  3. How much skin to make a pint of blood? by jomegat · · Score: 3, Interesting
    Just how much skin does it take to make a pint of blood? I would think a lot, but not having read the article, I wouldn't know.

    Seems to me they invented the reverse of the process that's really needed. It's a lot harder to get enough skin for grafting than it is to get blood for transfusions. Wouldn't blood-to-skin be a better conversion?

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    1. Re:How much skin to make a pint of blood? by RobVB · · Score: 3, Funny

      Just needs some reverse engineering.

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    2. Re:How much skin to make a pint of blood? by Kurofuneparry · · Score: 5, Informative

      A good question. The backwards conversion is impossible because the vast majority of blood cells are RBCs (Red Blood Cells or erythrocytes) and these have gotten rid of their nucleus, making them a cellular dead end doomed to destruction in about 120 days.

      Also, blood is mostly free water (plasma) and when RBCs are created their progenitor cells divide many times in the production process. Assuming that this process they're using is similar, you're talking about impressive volume multiplication in the conversion from skin to blood.

      Then again.... I'm an idiot .....

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  4. Re:How much blood can "a patch of skin" provide? by ColdWetDog · · Score: 3, Insightful

    No, no, no. No even wrong. However, the idiot FA is so devoid of information that yours is a reasonable assumption. A better intro.

    Useless note to Slashdot editors: Stay away from University PR Blurbs. A bigger waste of electrons than Fox News.

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  5. Re:How much blood can "a patch of skin" provide? by ColdWetDog · · Score: 5, Informative

    Oops, sorry, a real link.

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  6. Soylent Red is made of PEOPLE by amanicdroid · · Score: 5, Funny

    So they'll be able to grind up people and use them for blood transfusions, right?

  7. Re:Another Nail... by Jeff+DeMaagd · · Score: 4, Interesting

    Both sides of that argument had a lot of wrong impressions and misunderstandings. Using embryonic stem cells wan't directly about treatment, it was about research, there were properties that they wanted to understand. The biomedical community needed to learn how they work so that that knowledge can be used as a baseline to compare treatments. Interviewees on Science Friday did a pretty good job of explaining what they were looking for and why embryonic stem cells were desired for research. As for treatment though, I don't think ESC were ever going to be used in treatments except for very limited trials.

  8. A true breakthrough by JackpotMonkey · · Score: 3, Funny

    Now if we can just get the Crips to turn into bloods we may actually have something useful.

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  9. Re:Quantity? by Anonymous Coward · · Score: 4, Informative

    No, because most of that is water. Anyways, if you read the actual article in Nature, you will find out how much skin it takes. The information you want is in the supplementary information and they don't put that behind the paywall.

    http://www.nature.com/nature/journal/vaop/ncurrent/extref/nature09591-s1.pdf

  10. Really? by cprocjr · · Score: 4, Funny

    Cut off a patch of skin. Yeah, that'll stop the bleeding!

  11. Re:Another Nail... by twidarkling · · Score: 4, Funny

    Then you should probably shower more often.

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  12. Re:This should make vampires happy! by Chris+Tucker · · Score: 3, Insightful

    Dear Pathetic Concern Troll:

    Sorry about your butthurt.

    I suppose I should be sorry to tell you this, but America's founders were Deists, Unitarians, Atheists and Freemasons.

    Scarcely the creme of "christianity".

    Oh, also. Most Americans have no beef about using embryos for research that will help humanity. The research IS being done, despite your butthurt, in Europe and Asia, where christian lunatics have no say in the matter.

    So, here's the deal. People like you are dying out. Every generation more and more people reject your 'religion'. Your book of the collected myths, fables and superstitions of bronze age nomadic desert herders and the death cults they belonged to, is ignored and rejected.

    Sucks to be you.

    For the rest of us, not so much.

    kthnxbai!

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  13. Re:This should make vampires happy! by mr_mischief · · Score: 5, Insightful

    You should probably be aware that not all Christians are Catholics. There are plenty of Christians who believe in birth control (including many Catholics who disagree with their church over it).

    Most of them don't believe in abortion as a convenient form of birth control, though. Contraception is much easier, safer, and cheaper for the mother than abortion, even if you do think abortion is grand.

    Personally, I'm against abortion in principle unless it's an unusually dangerous pregnancy for the mother or the result of rape or incest. However, I know that making it illegal wouldn't stop it. It'd just drive it underground and make everybody involved -- mothers, fathers, doctors and nurses performing -- worse off. I think it should be, as President Clinton said, "legal, safe, and rare".

    Now, about the difference between IVF and abortion... IVF is not abortion. The embryos from IVF used for ECS research have not been implanted then scraped out by a surgeon. They are the spare embryos that were never implanted in the uterus. These are left over from women and couples trying to get pregnant and have kids, not preventing it. It's not about birth control in the common sense of the phrase, which is preventing births.

    Your argument seems to confuse quite a few topics. You also generalize quite a few groups into one you clearly disagree with the most. In your quest to vilify people as simpletons who don't grasp the issues at hand, you have oversimplified the topics and (probably intentionally) failed to even acknowledge the issues at hand are much more complex than you mention.

  14. Re:Another Nail... by physicsphairy · · Score: 4, Informative

    Even if it is a replacement, we're still years behind where we would be if the hicks didn't insist that we throw out the unused embryos.

    First sentence: bigoted language. Sounds like we're off to a good start.

    As near as I can gather you are intending this post toward the 'life-begins-at-conception' branch of the American pro life movement. In which case you are a bit confused in saying they "insist we throw out the unused embryos" given that they fight tooth and nail specifically to prevent unused embryos from being discarded. They often oppose IVF itself precisely because excess embryos are thrown out.

    As it stands we're destroying the extra stem cells from IVF instead of using them because the right won't allow scientists to use them.

    That's quite an uninformed statement. There really is no restriction on what can or cannot be done with embryos (apart from I believe in the state of Indiana). They are thrown out largely because there is no use from them. The restrictions which have existed (until Obama overturned them) regard limiting federally funded research to certain pre-existent lines.

    The reality is that we've got plenty of embryonic stem cells available without creating any more. Which really ought to be where the morals come into it.

    Where, exactly? At the point you align morals with "doing what's convenient and what we would have done anyway" I don't think you've really addressed a moral question at all.

  15. Re:Another Nail... by L4t3r4lu5 · · Score: 3, Funny

    I'm fairly sure a lot of the /. readership would like to participate in the creation of ESCs.

    [Giggedy]

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  16. Re:This should make vampires happy! by couchslug · · Score: 3, Insightful

    Most US Christians are either OF the religious right, or more importantly will never oppose it.

    The few on Slashdot aren't representative. The MANY who just voted the Teapublicans into power ARE representative, and just proved it yet again.

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  17. Re:This should make vampires happy! by PsychoSlashDot · · Score: 4, Insightful

    Personally, I'm against abortion in principle unless it's an unusually dangerous pregnancy for the mother or the result of rape or incest.

    How about in the case of a 15-year-old girl whose Christian parents who wouldn't talk about sex at all with her for fear that her hearing about it would encourage her to do it? So the girl doesn't know the fundamentals and trusts her new boyfriend who insists "condoms don't feel good" and "I'll pull out".

    What I'm asking is: how do you feel about unwanted and highly personally destructive pregnancies ultimately enabled by ignorance due to religion?

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  18. Re:Another Nail... by tom17 · · Score: 3, Funny

    Never mind can it help... Will It Blend?

  19. Re:This should make vampires happy! by drsmithy · · Score: 3, Insightful

    Most of them don't believe in abortion as a convenient form of birth control, though.

    I've never met anyone who thinks abortion is a convenient form of birth control, including women who have had several of them.

    Contraception is much easier, safer, and cheaper for the mother than abortion, even if you do think abortion is grand.

    It's also far from perfect.

    Personally, I'm against abortion in principle unless it's an unusually dangerous pregnancy for the mother or the result of rape or incest.
    [...]

    Now, about the difference between IVF and abortion... IVF is not abortion.

    I am fascinated to hear how you've managed to justify that little mental disconnect to yourself. What's the moral difference between creating an embryo in a test tube and then destroying it, and creating an embryo in a uterus and then destroying it ? By what measure can destroying an embryo that was almost certainly an accident be considered a greater crime than deliberately creating dozens (if not hundreds) of them with the absolute foreknowledge they would nearly all be destroyed (ie: creating them to destroy them) ?

  20. Re:This should make vampires happy! by Dog-Cow · · Score: 3, Insightful

    What kind of woman has several abortions without it being a (convenient) form of birth control?

  21. Re:Another Nail... by JTsyo · · Score: 4, Insightful

    Umm if you follow the Bible, God was willing to personally kill everything on the earth save a handful of people and animals. I don't see why a few billion embryos would be a issue for him, since he's not actively killing them but just allowing a natural process. If you want to place blame on him for his design then I think that opens up much bigger list of issues in human design.