Synthetic Skin Could Replace Animal Subjects'
fangmcgee writes "Synthetic skins are now good enough to mimic animal skins in lab tests, according to research that will appear in the June 5 issue of the Journal of Applied Polymer Science. Bharat Bhushan, a professor at Ohio State University and Wei Tang, an engineer at China University of Mining and Technology used atomic force microscopes to observe the responses of pseudo and rat skins to a generic skin cream. The result? Even at a scale of 100 nanometers — or one-thousandth the width of a human hair — all the samples
reacted in a similar fashion."
...when will they have synthetic leather shoes?
There's no -1 for "I don't get it."
How does the new skin taste after being fried in lard and sprinkled with salt and spices? Have they come up with synthetic beer yet?
Chaos maximizes locally around me.
I'll even volunteer my own skin sample if we can get this party started! Why use animal skin when you can test several strains of real human skin, rather than approximate animal skin? There are few long term uses for manufactured animal skin, but thousands of commercial applications for human skin...
moox. for a new generation.
...can't wait for my first synthetic rat skin coat.
One day, science will make me more like an animal. :3
I would have thought the obvious solution to the question of animal testing would be to require those who have a pecuniary interest in the business selling the cream to test the cream on themselves. They're humans with skin, aren't they? Deserving all the reward because they took all the risk, right?
(Bah, capitalism's been self-contradictory ever since the invention of the limited company. Wouldn't it be cool if the worker with an interest in X could set up a little fund for X and if he goes into huge debt there he can just write off that area of interest with no consequence and carry on?)
I'm not for animal abuse... this is great, spraying, rubbing stuff in animals/hides is sadistic. finally a invention that lessens the suffering in the world. Bravo!
I know I'll be going senile any day now, but the title doesn't parse.
Fuck systemd. Fuck Redhat. Fuck Soylent, too. Wait, scratch the last one.
The headline is somewhat misleading, it should say: "Synthetic Skin Could Replace Animal Subjects IN COSMETICS TESTING, SPECIFICALLY DERMATOLOGICAL PRODUCTS". For medical applications we are very far from such a breakthrough, owing mostly to the immense complexity of large biological systems, such as a living animal or human being. For the vast majority of animal testing, this might at best result in a reduced need for small pieces of skin tissue for basic research in laboratory settings, which is hardly the problem anyway.
"Everyone who believes in telekinesis, raise my hand..." - James Randi
.. who works with primates... I do so because I'm convinced there is no other way of collecting data that is important to our health and understanding about how our minds work. Food.. there are other sources.. but neuronal data, we're limited. I'm a big fan of the Reduce, Refine, and Replace idea, and if this is confirmed it's a big step, for 2 R's, and that's exciting.
Like BB guns?
Yep, that shot his eye out...better not sell this to little Johnny,,,
I don't post AC. I like my -1, Flamebaits. Trump/Sheen 2012 on the Batshit Insane ticket!
The implication of this news story is that we can replace test animals with "synthetic" tissue analogues but it simply isn't true (despite the fact animal libbers will spin it that way). Tissue based testing is only relevant if you are doing large scale testing to see if a possible effect occurs or are looking at a specific tissue type. The problem is that tissues do not function as individual units in the same way they function as part of an organism.
For example nearly any compound out there will kill or damage tissue samples at concentrations which even the most sickly lab rat wouldn't notice. Our systems have evolved to quickly remove toxins and to keep other compounds at homoeostasis, but this doesn't work when you isolate the tissues.
You can't replace whole organism testing with "synthetic" tissue samples and get useful science except at the most basic level. Hell, animal testing is often not even a good substitute for human testing it is just that the public got upset by the rampant testing of vulnerable people in the 40's - 70's so things have to be proven "safe" on animals first.
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CINC, 4th Penguin Legion
is the synthetic skin made of graphene?
... that Slashdot is still misusing the emblem of the international red cross :-(
If only we could compare the cumulative research costs to PETA's budget and lost economic potential.
Obviously science builds on science but the end result is probably going to save a hundred times as many animals as PETA for a fraction of the overall cost.
Let's use synthetic skin that almost certainly doesn't fully reflect the effects on an actual human or animal!
What if that new face cream you've got turns out to be a contact poison that only effects the liver? This fancy synthetic skin come with a liver? Oh it doesn't?
Sounds to me like a cost cutting measure by the company that is going to result in less safe skin care products, and their marketing is playing off the animal rights angle so people don't question it.
I understand the desire to cut out animal testing, and I fully support that. But the human body is complex, some chemical that makes your skin smooth or clears your nostrils might also cause nerve tissue damage. We quite simply cannot match the complexity of the human body synthetically right now, it is foolish and naive to think that you can test a chemical on only one part of the body and ignore all the other parts because they're not related.
Honestly, if a "revolution" in animal testing is going to occur, they watershed paper will not be out of this journal. The researchers appear to be microscopy specialists, not animal research specialists. Not to denigrate their work, but the literature is littered with people making grandiose claims about how their research can be applied with very little understanding about the other discipline where they suggest it could be useful.
Within a few years, a synthetic-skins rights activist group forms demanding for the stop to the "abusive treatment of synthetic skin" and demanding for these tests to be done on people instead.
This may not come off as politically correct, but since when has there been a rat skin shortage, and how much does this stuff cost to make?
But are they good enough for to replace my fur coat???
I'm not an animal rights activist. I don't have a problem with animal testing being legal, but if it's possible to get accurate results from a non-living thing that can only be good. Inflicting pain on animals was a necessary evil to prevent that pain from happening to humans, if we can eliminate the pain entirely, I say it's great.
LK
"Hi. This is my friend, Jack Shit, and you don't know him." - Lord Kano
Wow, this is quite ridiculous news.
100nm is not a small enough scale, It doesn't reach atomic bonding size, which atomic force microscopy is capable of.
Moreover, skin a very complex tissue formed with several highly different layers. You are not going to get the same feeling with just one polymer.
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