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Antibiotics Are Useless In Treating Most Sinus Infections
An anonymous reader writes "While doctors routinely prescribe antibiotics to treat sinus infections, researchers on Tuesday revealed that amoxicillin, the most commonly prescribed medication for nasal cavity inflammation and sinuses, was just as effective as a dummy pill. Researchers from the Washington University School of Medicine in St. Louis, Missouri, found that there was no significant difference in symptoms between patients taking amoxicillin to those who took the placebo three days after starting the pills were administered."
You can't effectively treat biofilms with antibiotics. And that is exactly what this type of infection is--a biofilm.
A better approach is the use of biofilm "release" enzymes that signal the cells within the biofilm to stop producing EPS and detach from whatever surface they are clinging to. Use of such enzymes alongside antibiotics in a medical setting is likely to work even better.
Most sinus infections are viral. Nothing to see here.
Great warrior...hrmph! Wars not make one great.
Big leap from "no significant difference in symptoms between patients taking amoxicillin to those who took the placebo"
to "Antibiotics Are Useless In Treating Most Sinus Infections". How many bugs are resistant to amoxicillin at this point?
How many of the patients had bacterial infections?
more cowbell
A) Someone's got a sense of humor: "The primary outcome was measured using the modified Sinonasal Outcome Test-16 (SNOT-16), a validated and responsive measure."
B) They did no testing whatsoever to ensure the sinus infections _were_ bacterial - but they apparently usually are, and are usually diagnosed as such symptomatically instead of by culture (in other words, they followed normal practices in deciding who to give antibiotics to).
C) They did no testing to see if resistant bacteria could be isolated from any patients.
Putting B and C together...clearly the medical community is overprescribing antibiotics, but there may be some question of whether it's resistant bacterial infections or poor diagnosis of bacterial vs. viral infections.
Antibiotics are very quick - their major effect is in the first couple of days of a 10 day (2 week, whatever) course. The extra week or more of pills is to make absulutely sure that everything that can be killed off, is. This is to prevent (or at least restrict) the chance of any drug-resistant strains developing.
One of the major problems in countries like France (where drugs are handed out like sweets) and in the developing world (where people can't afford the whole course, or save some for "next time") is people not finishing up a full course of antibiotics because 3 days in, they feel well and can't see the need to swallow any more of the evil pills that have given them diarrhoea and other stomach problems (the main side effect of broad spectrum antibiotics....).
Troc's dubious podcast and blog: http://www.trocnet.net
THE AC submission was alarmist and wrong.
The research did not show the anitbiotics are useless.
It showed the Amoxicillin had no significant statistical difference at day three. BUT statistically significant results on day 7, no difference on day 10.
What this means is the people taking Amoxicillin got better sooner.
The person who wrote the headline and summary should be ashamed of themselves.
The Kruger Dunning explains most post on
Doctors have a tendency to recommend things that only they can recommend: prescription drugs, surgery, etc. They figure if you could do it yourself you'd have already done it.
But there's an ancient treatment for sinus problems that works really well: nasal irrigation. Basically, you add 1/2 tsp salt to a cup of water, and flush that through your nasal cavity.
Wall Street's media was overjoyed when someone with parasites in their water supply recently died after they used their neti pot. So boil your water first if that's a problem where you live, mkay? (This is covered on the link above...)
Learn the rules so you know how to break them properly.
www.teslabox.com
A Mayo clinic study found 70% of sinus infections are viral instead of bacterial, so antibiotics actually make the infection worse. In addition, the antibiotics harm the rest of your immune system, leaving your worse off than before. My ENT introduced me to anti-viral nasal sprays for sinus infections. More of the drug reaches the infection and your GI system is left unharmed. The catch is they must be compounded at a pharmacy, need to be refrigerated, and are only good for 30 days. Many insurance companies cover them, but a lot of doctors don't know that option exists and just prescribe antibiotics.
Just ask for homeopathic medicine.
I inherited bad sinuses from my mother who occasionally gets wicked sinus infections and has to go on hardcore antibiotics, the kind that WIPE your digestive tract and turn your poo white.
Fortunately for me genetics diluted the problem and I don't get one more than once a year usually. I've tried to tough it out, load up on decongestants and expectorants (due to drainage) etc and all that happens is it gets my throat torn up like hamburger from the infected runoff combined with coughing. Lucky me, I'm going through my yearly round of that right now actually. I started myself on decongestants immediately and have been pounding down pepsi almost nonstop to try to keep my sinuses and throat clear, but it still looks like the throat version of red-eye in there. I might actually beat it without antibiotics for the first time this time since I've jumped on it so aggressively.
In the past it's usually been the same story. Try to use over-the-counter meds for a week, finally it is getting so bad that the yellow mucus overnight has my throat destroyed by morning. (which will improve somewhat during the day, but not enough, it's a losing battle day to night) Enough of those and I can't stop coughing and I sprint into the local "convenient care" before work and a random doc looks at me and prescribes a decongestant and expectorant (that cost 2x the OTC usually) saying he doesn't want to give me antibiotics YET. Thanks.
So I'm back in the office 3-4 day later, almost unable to talk, haven't slept in days, throat killing me, and throat is totally red with green mucus streaking down in the back. "Ooooh! you have a bad sinus infection now! Here's some antibiotics!" Thanks. Now why couldn't we have just done this three days ago instead of putting me through two days of hell?
So the last two times I went in I relayed the above story and they conceded maybe antibiotics before it gets REALLY bad is a good plan for me. And I was sooo thankful, instead of it taking several more days of winding down misery, another two weeks in all, one round of refills to clear up, it was much better the very next day and cleared up in 5 days, both times.
Whoever says antibiotics don't help sinus infections is a quack. I seriously wonder what would happen to people like me if there were no antibiotics, could it get bad enough to hospitalize or kill me?
I work for the Department of Redundancy Department.
Your intestine has about a kilogram of symbiotic bacteria, with dozens of major species and hundreds of minor species. When you take antibiotics, you wipe out some or most of those species.
The bacteria in yogurt (usually a single species) are completely different. You can't repopulate the normal bacteria of your intestine with yogurt.
Nobody knows exactly how bacteria repopulate the bowel, but one thing you could try is a fecal transplant -- in other words, eat shit. This is not a standard medical procedure, but it's under serious investigation.
One of the problems with destroying the normal gut flora with antibiotics is that the gut is a major immunological organ. The immune system (all those white blood cells) has to decide whether a bacterial species is a normal symbiote or a pathogen, which is difficult and inaccurate. If you wipe out the normal flora and start again, your immune system might make mistakes.
Nobody knows what causes autoimmune diseases like multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosis, Crohn's, inflammatory bowel disease, etc., but wiping out the normal gut flora with antibiotics is a plausible mechanism.
So using antibiotics when you don't need them, in addition to promoting antibiotic resistance, might give you one of those horrible autoimmune diseases.