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New Avenue For MRSA 'Superbug': Pigs

smitty777 writes with news that researchers have discovered another way methicillin-resistant Staphylococcus aureus (MRSA) bacteria are developing resistance to antibiotics. According to the study (abstract), the bacteria made the jump to pigs on livestock farms, developed greater resistance through the rounds of antibiotics commonly used to keep the pigs healthy, and then jumped back to humans. "The important development in the story of ST398 is its move back off the farm into humans, causing first asymptomatic carriage in that original family, and then illnesses in other Dutch residents, and then outbreaks in healthcare settings, and then movement across oceans, and then appearance in retail meat, and then infections in people who had no connection whatsoever to farming—all from an organism with a distinctive agricultural signature. That’s an important evolution, and an illustration once again that, as soon as resistance factors emerge, we really have no idea where they will spread. So it would be a good idea to take actions to keep them from emerging, or at the very least to implement surveillance that would allow us to identify them when they do."

22 of 135 comments (clear)

  1. Who was the idiot who just let this happen? by HBI · · Score: 4, Insightful

    Seriously, why was it considered ok to dump antibiotics into animal feed? It seems like total idiocy from this angle, regardless of the short term benefits.

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    HBI's Law: Frequency of calling others Nazis is directly correlated with the likelihood of the accuser being Communist.
    1. Re:Who was the idiot who just let this happen? by Anonymous Coward · · Score: 5, Insightful

      Seriously, why was it considered ok to dump antibiotics into animal feed? It seems like total idiocy from this angle, regardless of the short term benefits.

      Because factory farms make more money that way, duh.

      They don't give them antibiotics to treat disease. They give them antibiotics because they fatten up faster, I guess cause their immune systems atrophy so they can put more metabolic energy into growth.

      But no really, if factory farms didn't save that penny or two per hog we'd ALL be in DEEP TROUBLE then.

    2. Re:Who was the idiot who just let this happen? by Rogerborg · · Score: 4, Insightful

      Next quarter's profit uber alles.

      That's it. That's all there is to it.

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    3. Re:Who was the idiot who just let this happen? by Anonymous Coward · · Score: 3, Insightful

      It seems like total idiocy from this angle, regardless of the short term benefits.

      It's a free market. The farmer using antibiotics to increase growth isn't the one paying the costs of those benefits. He's be a idiot not to maximize his profits. Farming is very competitive (low margins), so if you make enough mistakes you'll go bankrupt very quickly.

    4. Re:Who was the idiot who just let this happen? by BlueParrot · · Score: 4, Informative

      The risk has been known for some time, and thus the practice is mostly banned in the EU, with the exception of two compounds used in poultry feed.

      In the US it is mostly unregulated, and nearly 70% of antibiotics are used for animal feed.

      Can't say I am terribly surprised.

    5. Re:Who was the idiot who just let this happen? by slacker22 · · Score: 3, Insightful

      This is especially true in countries where farms haven't evolved into 'super-farms'. You have the likes of dairy-farmers who are heavily exposed to the volatility which comes part-and-parcel with specialization (i.e. lack of diversification). For a small family farmer, there is limited benefit to thinking long-term. Their livelihood is tied up with next quarter's profit and they don't have the sophistication/time to be hedging exposure on futures exchanges.

    6. Re:Who was the idiot who just let this happen? by SydShamino · · Score: 5, Insightful

      Libertarianism cannot cope with tragedy of the commons. You know when libertarians say that positive rights are not guaranteed human rights, because they force someone else into slavery? It gets mentioned on Slashdot pretty commonly.

      Your right to live in a world where antibiotics work obliges pig farmers to lower their efficiency and lose money, because it is more cost effective to farm with antibiotics. Likewise, your right to live in a world with breathable air and survivable temperatures and arable land obliges coal factories and car manufacturers to capture their exhausts, including carbon. Libertarians would have to classify these rights as positive rights because they oblige others to take action.

      Some libertarians will say that the court system can handle this, because you can sue those that cause you demonstrable harm. But in a case like this, exactly how much money do you think each person who dies from MRSA can extract from a Dutch farm? And isn't it better to live in a world without MRSA and more government regulation than a world with MRSA and more lawsuits?

      Anyway, if the right to live in a world free of man-made and man-contributed diseases, where the temperature supports life and there is potable water to drink, is a positive right, then why the fuck do we bother with negative rights like speech and assembly at all? They are sort of meaningless when we're all dead. We all should have standing to take action when the commons could be violated, and the way we do that is through government regulation.

      Sorry for a rant on the pointlessness of negative rights without positive rights, but I think that's why it was considered ok to dump antibiotics into animal feed.

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    7. Re:Who was the idiot who just let this happen? by whoever57 · · Score: 3, Interesting

      Seriously, why was it considered ok to dump antibiotics into animal feed? It seems like total idiocy from this angle, regardless of the short term benefits.

      Farmers just don't understand the issue. I heard an interview with a representative of some group of farmers discussing this issue last year. He was defending the use of antibiotics for "growth promotin" (sic) because they only used a low dose! Of course high doses may have their problems also (if it would allow some to get to the human food supply), but he did not seem to understand that using low doses (presumably somewhat inconsistently administered through the animal feed) could lead to resistence in bacteria.

      --
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    8. Re:Who was the idiot who just let this happen? by ackthpt · · Score: 5, Informative

      Seriously, why was it considered ok to dump antibiotics into animal feed? It seems like total idiocy from this angle, regardless of the short term benefits.

      One reason I became a vegetarian was because I learned about all the antibiotics in Pork/Beef/Poultry. I suffered severe Streptococcus infections in the respiratory system. When learning I was effectively on Antibotics, constantly, due to my diet, thus prescription antibiotics were having no observable effect, I realized I was fighting Streptococcus which was already resistant, thus I was getting these painful and long duration infections.

      Understand this: Antibiotics are targeted toxins, most likely to have a greater effect upon certain organisims, while there would be some collateral effect upon the host, including degradation of the immune system.

      After about 2 years without antibiotic-laden foods I found I stave off these infections more effectively and when I have them the duration is significantly decreased.

      Keeping like livestock (or plants) in a dense concentration provides an ideal breeding ground for organisms to prey upon them, further, to mutate as the turnover can be far more rapid than in the wild. Add to that antibiotics and you have the ideal incubator for super-bugs. Victims of our own way of production. Won't get better with bigger factory farms, either, it's a cycle which builds upon itself.

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      A feeling of having made the same mistake before: Deja Foobar
    9. Re:Who was the idiot who just let this happen? by fred911 · · Score: 4, Informative

      "..I would be arrested."

      No you wouldn't. You can buy many prescription antibiotics without a prescription at your local pet store. Sometime look at what is sold over the counter, in the fish section. Larger quantities can be found farm supply stores.
        It's the same stuff with "not for human consumption" labels.

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    10. Re:Who was the idiot who just let this happen? by Daniel+Dvorkin · · Score: 5, Informative

      It's considered ok because there isn't any real scientific evidence there is an issue. And it's been studied since at least 1990.

      Do you want to cite some of those studies to back up your claim? A quick Pubmed search turns up a whole lot of papers indicating that the use of antibiotics in animal feed is a major contributor the rise of resistant strains.

      --
      The correlation between ignorance of statistics and using "correlation is not causation" as an argument is close to 1.
    11. Re:Who was the idiot who just let this happen? by mikael · · Score: 3, Informative

      Private Eye have been saying this for at least the past decade, but no-one really wanted to know.

      Pumping animals full of antibiotics mean that they divert less internal biological resources like protein and fat to fighting infections, and bulk up instead. But those antibiotics just encourage the evolution of resistant bacteria that can survive in those conditions.

      --
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  2. Re:thanks meat eaters! by TheReaperD · · Score: 5, Insightful

    We can be meat eaters and still be alarmed about the health and quality of the food supply. Being a vegetarian/vegan has nothing to do with it. There are serious concerns about our grain, vegetable and fruit supplies as well between pesticides, GMOs and processed foods. Quit sticking your nose to the sky and actually look at the whole problem.

    --
    "Be particularly skeptical when presented with evidence confirming what you already believe." -
  3. Re:thanks meat eaters! by tidepool · · Score: 3, Funny

    Shit, I hit the wrong mod button; Apologies! So , I am commenting on your post, of which I tried to mod 'insightful', and instead, erasing my mod of 'redundant' in the process.

    Cheers!

  4. Political solutions by Average_Joe_Sixpack · · Score: 5, Funny

    Authoritarian Left  : Antibiotics in animal feed increase yields thus benefiting the proletariat.

    Authoritarian Right : Antibiotics in animal feed increase yields thus benefiting the shareholders.

    Libertarian Left    : If the superbug kills you then you can sue the farmer in court.

    Libertarian Right   : If the superbug kills you then you can sue the pathogen in court.

  5. Re:thanks meat eaters! by ChromeAeonium · · Score: 4, Interesting

    pesticides, GMOs and processed foods

    Processed foods I'll give you. People really should move back to whole foods, preferably vegetables, in place of highly processed grains and sugars. Pesticides have their place. There's a lot to be said for moving more toward IPM strategies than we currently have, sure, but they are a necessary evil. Heck, even plants produce their own pesticides. They don't make those secondary metabolites for the fun of it. And it's funny that you mention GE crops as a problem in the same sentence as pesticides, considering the effects they've had on pesticide usage. There's plenty of criticisms to make about how people eat and how food is grown. Processed foods are one. Monoculture & lack of biodiversity, over-fertilization & run-off, water scarcity & depleting aquifers, ect. would be much better practices to gripe about, and issues like peak phosphorus, declining agricultural research, and agriculture in the face of climatic issues are also worth considering. Pesticides and especially biotechnology (in and of themselves anyway) are not...not that pesticide use shouldn't be reduced where possible.

  6. Re:thanks meat eaters! by ChromeAeonium · · Score: 4, Informative

    Anyone not aware of the risks GMO's are posing on society should really do some reading.

    Anyone who bought into the fearmongering and often times outright lies of the anti-GE campaign should do some reading.

    The scientists that are developing these seeds and pesticides wont even go near them because there is no long-term research on what risks they could offer 10 or 20 years from now.

    Funny, I've spoken with scientists who do just that. I didn't notice them eating any differently than anyone else. I've transformed plants before. I have no problem eating genetically engineered food. I do it all the time.

    And there has been long term research (unless you define long term as X+5 so you can always keep moving that goalpost). Darnedest thing is though, what hasn't been done is for someone to propose a plausible mechanism as to why GE crops would be dangerous. We know the genes inserted (cry genes, epsps, bar, nptII, PRSV/CMV coat protein genes) are safe, but for all the cries of 'what might happen' no one has explained what in GE crops allegedly hurts you, how it is produced, its mode of action, ect. I suppose GE crops could kill us all 20 years down the road, but only in the same sense that the smallpox vaccine could do the same thing, or that there could be an invisible heatless dragon in my garage waiting to eat me. After so much study has been done, you can only play the appeal to ignorance card for so long, then the burden of proof shifts to the people believing that to prove it.

    Scarey shit.

    What's scary is that agriculture is staring down an increasing population, global climate change, increasing energy costs, peak phosphorus, increasing pressure on fresh water resources, evolving pests and pathogens, desertification, deforestation, greater demand for animal protein, and agriculture has to take care l that without expanding the amount of land under the plow, and we've got people having not based in science blanket opposition to what will probably go down as the most significant breakthrough in plant improvement since unraveling Mendelian genetics. Now THAT is scary.

  7. Be careful by yog · · Score: 3, Informative

    Wash your hands after handling meat, wash all the implements and counter tops that may come into contact with raw meat. Cook the meat well.

    Be careful with restaurants; to minimize your chances of exposure, just say no to eating out unless you can't avoid it. Once in a while is OK but several times a week is a good way to pick something up, if not MRSA then hep-C or some other nasty microbe that the waiter carried to your plate from someone else's plate. If you don't see the waiters wash their hands after taking your plates away, then you can bet they didn't wash their hands after taking the previous customer's plates either. When the water boy comes over to refill your glass, hand it to him by the rim, so he's forced to pick it up by the bottom. Use a straw.

    And stay out of hospitals. Those places can make you sick. MRSA is one nasty infection that you don't want to get, but there are others as well. Basically it's a rather closed environment full of sick people, and also full of well people carrying the germs from one sick person to another, and your life may depend on how well they washed and sanitized their hands before touching you.

    This may seem kind of paranoid, but we live in an increasingly crowded and mobile world where a nasty little microbe in some little corner of the globe can make its way into your soup literally days or hours later.

    --
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  8. Re:thanks meat eaters! by geekoid · · Score: 4, Interesting

    You can actually be a perfectly healthy vegetarian; but you need to be smart and knowledgable about your diet.

    Jack la Lane was a vegetarian, and who could probably kick most people ass, and rarely got sick.
    He was intelligent about how he ate, and he exercised every day.

    Most vegetarians just eat anything as long as it's not meat,and don'r exercise.

    Oh, he did start eating meat when he was around 65, or so. There wasn't any other way to get certain fats an elderly person needs. Once again, he was smart about his diet.

    I am not a vegetarian, but I would like to see people pull back on meat portions. Cause there is a difference between eating meat, and eating a pound or more of meat a day.

    --
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  9. Re:thanks meat eaters! by vux984 · · Score: 3, Insightful

    . I lead a very active lifestyle -- I bike to work, scuba dive, teach spin classes, and work out regularly. (I'm known as one of the tougher spin instructors.) I go to the doctor about once a year to get a checkup.

    And this is why you are healthy.

    I eat a vegan diet

    Not this.

    Granted your diet likely involves not loading up on potato chips, and twinkies every day... so a "healty diet" is important. But it doesn't need to be "vegan" to be "healthy".

  10. Re:thanks meat eaters! by MisterSquid · · Score: 3, Interesting

    Darnedest thing is though, what hasn't been done is for someone to propose a plausible mechanism as to why GE crops would be dangerous.

    You're fail to understand what drives some scientists to adhere to the principal of least harm.

    If there are possible adverse, irreversible effects of human activity on our ecosystem, and the state of our knowledge is such that we can as a species initiate such effects without understanding how they manifest, then one school of thought is to halt human intervention/activity in those potentially sensitive shared domains.

    Your shouting at length to "explain how this harm may come about" when we do not have the technical understanding about how such harms may come about is, despite your education and rational abilities, stupidity in action.

    The moral of the story here is there are things we don't know that can cause great irreversible harm and that regulating/preventing activity in certain circumstances can avoid these harms.

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    blog
  11. Re:thanks meat eaters! by nbauman · · Score: 3, Interesting

    Darnedest thing is though, what hasn't been done is for someone to propose a plausible mechanism as to why GE crops would be dangerous. We know the genes inserted (cry genes, epsps, bar, nptII, PRSV/CMV coat protein genes) are safe, but for all the cries of 'what might happen' no one has explained what in GE crops allegedly hurts you, how it is produced, its mode of action, ect.

    Actually there is a mechanism. One of the big companies tried to insert a gene into brazil nuts (either BT or herbicide resistance) and found out that it produced an unexpected immune response because of the way the protein was folded. They abandoned the project, and wrote an article about it in the New England Journal of Medicine, which I read. That's the poster child of the anti-GM movement.

    I'm not particularly worried about GM food. I eat GM cornflakes every day (as I found out afterwards). I couldn't avoid GM food if I wanted to. And I do get annoyed when I see the truly stupid arguments against GM food by political science majors who never took a biology course.

    But give the critics their due. We in the US turned our entire corn and soybean production into GM crops without notifying consumers about it, and without letting them make their own decisions as consumers who supposedly rule this wonderful free market. There was no labeling and food processors weren't even allowed to sell their food as GM-free for years. Monsanto may believe in a lot of things but they certainly don't believe in a free market.

    You can't even get GM-free food in this country any more because the GM strains have contaminated everything else, and when the food companies try to sell grains to Europe, where there are restrictive laws, they're forced to go to the international trade commission and ask (or rather demand) that they be allowed to define food with no more than 1%, or 0.1% (or whatever) GM food as GM-free.

    You believe in science? The scientific method says that you have to take your hypotheses and beliefs, and subject them to confirmation in the real world. If you believe that GM food is safe, you have to prove it with data. That's not as easy as you make it out to be. It's not enough to feed a hundred mice for 6 months and see if any of them keels over. It's not even enough to feed 300 million Americans GM corn and soybeans for 20 years and see if any of them keels over, as we did. It is actually impossible to prove generically that GM food is safe. You have to take each specific food.

    Let's suppose you're really, really smart and you thought really, really hard, and you couldn't think of a plausible mechanism by which GM food can do harm. That doesn't mean there isn't one. Nobody would have thought that inserting a BT gene into brazil nuts would produce an immune reaction, but it happened.

    I don't care how smart you are -- you don't understand the human immune system well enough to predict what can go wrong, because nobody understands the human immune system well enough to predict what can go wrong. That's why that contract lab in England injected a half dozen test subjects with a new drug that caused an unexpected autoimmune reaction and caused one kid to lose his fingers a few years ago. I was taught that proteins were all destroyed in the digestive system, but then I saw in the New Scientist that some of them do survive. What can they do?

    I went to a meeting where a scientist from the Natural Resourced Defense Fund made the case that GM foods might cause unexpected immune reactions. I thought it was bullshit. Then I found out about the brazil nuts. What other totally unexpected problems could we have? You don't know. They've got a point.

    I will stipulate that Jeremy Rifkin is an idiot, and if we listened to him in 1984 we wouldn't have been able to develop T cell growth factor, we wouldn't have developed a test for AIDS, and we wouldn't have developed treatments for AIDS. We wouldn't have sequenced the human genome, we wouldn't have developed imatinib and CML would st