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Early Exposure To Germs Has Lasting Benefits
ananyo writes "Exposure to germs in childhood is thought to help strengthen the immune system and protect children from developing allergies and asthma, but the pathways by which this occurs have been unclear. Now, researchers have identified a mechanism in mice that may explain the role of exposure to microbes in the development of asthma and ulcerative colitis, a common form of inflammatory bowel disease. The researchers show that in mice, exposure to microbes in early life can reduce the body's inventory of invariant natural killer T (iNKT) cells, which help to fight infection but can also turn on the body, causing a range of disorders such as asthma or inflammatory bowel disease (abstract). The study supports the 'hygiene hypothesis,' which contends that such auto-immune diseases are more common in the developed world where the prevalence of antibiotics and antibacterials reduce children's exposure to microbes."
All those bullies sticking my head in the toilet were just trying to help expose me to germs. I should send them a thank you note.
Most of my anecdotal observations in life tend tend to agree: life in a bubble isn't good for you, even if you never leave it.
Ah, but the big questions remains unanswered: Does the basement count? Do Dorito bits count as dirt? Are keyboards a good source of antigens for the early immune system?
Faster! Faster! Faster would be better!