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Scientists Clone Sheep With 'Good' Fat

redletterdave writes "Chinese scientists have cloned a genetically modified sheep containing a 'good' type of fat found naturally in nuts, seeds, fish and leafy greens that helps reduce the risk of heart attacks and cardiovascular disease. The gene, which is linked to the production of polyunsaturated fatty acids, was inserted into a donor cell taken from the ear of a Chinese Merino sheep. The cell was then inserted into an unfertilized egg and implanted into the womb of a surrogate sheep. With any luck, this process could be replicated in the future to clone more animals for safe and healthy consumption."

43 of 233 comments (clear)

  1. Genetically Modified Hogs next? by tomhath · · Score: 4, Funny

    Healthy bacon. Mmmm.

    1. Re:Genetically Modified Hogs next? by erroneus · · Score: 5, Interesting

      I kinda disagree with that. Yes, current meats are kinda... bad in large amounts but that is largely because of the way the body works... if you live on mostly meats without much in the way of carbs, you'll be just fine and your body will consume those "bad fats." Problem is, it is really hard to eat that way... really hard. It's good to mix things up. So if we can have meats without the negative health impact when mixed with other things, we will get the benefits of the protiens and all the good things meat offers and still be able to eat it with things more carby... like spaghetti in meat sauce... :)

    2. Re:Genetically Modified Hogs next? by MyFirstNameIsPaul · · Score: 4, Informative

      This is already a reality with naturally-fed animals. For example, beef can provide us with all the healthy fats and oils we need when the cow is grass-fed and range raised. When chickens are raised on a diet or worms that grow in fresh cow dung, the consistency, flavor, and overall health of their eggs is substantially higher than what is generally available in the supermarket.

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    3. Re:Genetically Modified Hogs next? by Genda · · Score: 2

      I'd love to get my hands on some meat that simultaneously tastes like pork and fish.

      Her name is Shiela, and she's not all that interesting... really.

    4. Re:Genetically Modified Hogs next? by Genda · · Score: 5, Funny

      ECOPIG!!! Swine of environmental justice!!!! Wherever evil agro-corps commit atrocities against the natural landscape ECOPIG and his sidekick PIGGY-SUE will snort in the face of danger and send those business hogs back to Wallstreet squealing!!!

    5. Re:Genetically Modified Hogs next? by CAIMLAS · · Score: 4, Interesting

      How is it difficult to eat "that way"?

      IMO it's very easy to have a diet which is primarily meat. You don't have to eat a large pork rind for breakfast or a side of bacon every other week, but if you've got good quality meat available, short of filling up your cart with lots of different meats and a handful of odd veggies at the grocery, it's really not that hard.

      You need less food (in volume) if you're eating meat than if you were eating a 'mixed' carb-heavy diet, too, which certainly helps. Judging from what I've seen vegans or even vegeterians deal with, it's certainly easier (in terms of food prep and quantity) and less costly.

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    6. Re:Genetically Modified Hogs next? by kamapuaa · · Score: 2

      Jim Fixx popularized jogging with "The Complete Book of Running," then died of a heart attack at age 52. An autopsy revealed a cornorary artery that was 95% blocked. Sample size of 1 and all that.

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    7. Re:Genetically Modified Hogs next? by value_added · · Score: 4, Insightful

      Worth pointing out that the same applies to vegetables and fruits. Winter tomatoes grown in the sandy soils of Florida can't really be compared nutritionally to what someone can get out of their own garden.

      Ultimately, it's all about the "ingredients". That's long been considered a truism for chefs in the kitchen as it is for someone involved in raising animals. That this is routinely overlooked, glossed over or otherwise dismissed in the pursuit of economic interests and efficiencies is both funny and tragic. Funny in the sense of "What the hell did you expect?", and tragic in the sense of engaging in (and wasting time and effort with) tortured discussions of good/bad ideas and practices which, ultimately, are workaround to workarounds.

    8. Re:Genetically Modified Hogs next? by RulerOf · · Score: 4, Informative

      Then you die like the doctor who came-up with this "eat lots of fat" diet.

      If you think that his diet was the cause of the fall and resulting head trauma that killed him, I've got some news for you: you're a fucking moron.

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    9. Re:Genetically Modified Hogs next? by Oswald · · Score: 5, Funny

      When chickens are raised on a diet or worms that grow in fresh cow dung, the consistency, flavor, and overall health of their eggs is substantially higher than what is generally available in the supermarket.

      For some reason, the more you talk up animal products, the more I want to become a vegan.

    10. Re:Genetically Modified Hogs next? by sunspot42 · · Score: 3, Interesting

      >Then you die like the doctor who came-up with this "eat lots of fat" diet.

      If you're referring to Atkins, he died after slipping on the ice, falling, hitting his head and going into a coma. Diet had nothing to do with that (unless he was drunk at the time!).

      I dropped carbs pretty much completely out of my diet a year ago, and started eating meat with every meal after having been a vegetarian for over 20 years. I've dropped from about 215 to 165lbs, and my cholesterol has dropped from over 250 to 200. My "bad" cholesterol has plummeted, and my "good" cholesterol has skyrocketed. My triglycerides are way down. So's my blood pressure. So all of my markers correlated with heart disease have improved, dramatically. And I sleep better and have more energy.

      Atkins was right. I just gotta be more careful than he was when I step on icy sidewalks!

    11. Re:Genetically Modified Hogs next? by drinkypoo · · Score: 4, Informative

      For some reason, the more you talk up animal products, the more I want to become a vegan.

      I favor meat licenses. You should have to tour a slaughterhouse or kill and cook an animal before you're allowed to eat meat. Let's have a little recognition of where our food comes from and what happens to it on the way. I've killed, skinned, cut up and cooked a deer, I've caught and killed a goose by hand and it went in the stew... I understand I'm eating life, and what that actually means, and I'm cool with it. I know that when you cut them, stuff comes out you don't want on your hands, and yet after you grill them they are goddamned delicious, and good for you. If I eat a typical meal (notably including a little carb bomb) I feel stuffed and weighted down. If I just eat a big fucking steak I feel great, full of energy, have a nice crap the next morning and I'm up and at 'em. Meat, it's what's for dinner.

      BRING ON THE CRAPWORMS

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    12. Re:Genetically Modified Hogs next? by ArcherB · · Score: 3, Insightful

      When chickens are raised on a diet or worms that grow in fresh cow dung, the consistency, flavor, and overall health of their eggs is substantially higher than what is generally available in the supermarket.

      For some reason, the more you talk up animal products, the more I want to become a vegan.

      Funny you would say that. Have you seen the crap that vegetables are grown in? As someone who grows his own vegetables, let me tell you how to make the most healthy soil available.

      1) Start with fresh manure from a herbivore. That's crap from a vegetarian to you city folk. Bunny crap works the best when mixed with urine soaked saw dust. Horse manure mixed with urine soaked bedding, cow, goat,llama or other large, herbivore mammal will also work.
      2) Allow it to rot for a few months. (This is a good additive as is, but we can make it better)
      3) Feed the rotted manure it to worms. Red Wigglers are the most common.
      4) Separate the live worms from the worm crap.
      5) The crap that is left is the best soil you will ever run across and it will produce the greatest vegetables on the planet.

      That's right. Crap from crap fed worms is the best soil imaginable. Of course, that re-crapped crap is what is absorbed into the plants, mixed with water, CO2 and sunlight to make the vegetables you eat. And they are delicious!

      Of course, some animal products can be beneficial as well. Bone meal (ground up animal bones), blood meal and fish emulsion are also beneficial, but nothing compares to good old worm shit.

      Don't think that just because you are vegetarian that you are not eating crap. Manure is the most important product in agriculture behind sunlight and water.

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    13. Re:Genetically Modified Hogs next? by jandersen · · Score: 2

      You need less food (in volume) if you're eating meat than if you were eating a 'mixed' carb-heavy diet, too, which certainly helps. Judging from what I've seen vegans or even vegeterians deal with, it's certainly easier (in terms of food prep and quantity) and less costly

      Eh? Less costly? Of course, I don't know what kind of vegan you have seen, but I assume they are the kind that live on this planet (as opposed to Vegans, if you know what I mean).

      Personally, I have gone from eating loads of meat about 6 years ago to eating very little of it - I've just lost the appetite for meat, somehow. I can cook a very good bean curry, which will provide my lunch for about 3 or 4 days, for as little as 2 GBP. It takes longer to cook, but the actual work involved is about 10 minutes - can your meat diet beat this on price and effort?

  2. my wife... by crutchy · · Score: 4, Funny

    ...gets a bit of "good fat" occasionally

    1. Re:my wife... by jhoegl · · Score: 2

      So... your neighbor?

  3. First clone of first post! by larry+bagina · · Score: 3, Funny

    HeaIthy bacon, Mrnrnrn,

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    1. Re:First clone of first post! by Nursie · · Score: 3, Insightful

      I would dispute 'very good'.

    2. Re:First clone of first post! by modernzombie · · Score: 2

      I eat turkey bacon regularly and it tastes nothing like real bacon. It tastes more like Bologna than bacon.

  4. Ethics of GMO animals? by MrEricSir · · Score: 2

    GMO plants is one thing, but animals? I can't quite put my finger on why, but someting about this seems... troubling.

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    1. Re:Ethics of GMO animals? by englishknnigits · · Score: 4, Funny

      Are you saying you would rather eat an animal that doesn't want you to eat it?

    2. Re:Ethics of GMO animals? by metrometro · · Score: 2

      Because you can't treat a plant inhumanely. Sheep can suffer. And we know how compatible capitalism and bioethics is.

    3. Re:Ethics of GMO animals? by Anonymous Coward · · Score: 3, Insightful

      We've been doing GMO for centuries, many of them. The difference is now we're able to make specific, targeted changes much more rapidly, whereas before we had to breed features in and out of our food species over very (very very in some cases) long periods with only a partial ability to control the outcomes well. This whole argument is kinda like hearing someone say "You genetically modified a housecat to not have claws? That's so unnatural!" .. as if housecats are at all natural. We created what they are today over a long period (well, and some more modern breeds/features over a shorter period when we understood breeding properly). If you want a "natural" pet, trying having a cougar sit in your lap and purr every day (insert cougar dating joke here).

      All of the modern major food supply species: Cows, Pigs, Chickens, etc... are all incredibly unnatural species already, even before the advent of proper GMO. They'd go extinct in a heartbeat without us growing/farming/protecting them until we eat them. We engineered them as food sources, they're not natural!

  5. Creepy mental image by Grayhand · · Score: 5, Funny

    The fact they got the fat gene from a round worm gave me this mental image of a 100lb round worm covered in sheep's wool. I doubt counting those wouldn't help me get to sleep and would likely give you nightmares.

    1. Re:Creepy mental image by xstonedogx · · Score: 2

      Wait until they cross them with cinnamon trees.

    2. Re:Creepy mental image by Solozerk · · Score: 2

      The Spice expands consciousness.

  6. Re:Somatic cell = old mitochondria by NoKaOi · · Score: 2

    If you're breeding for food purposes, I don't think longevity matters that much. Dolly lived for much longer than the usual term for lamb that are bred for meat.

    Except that breeding the old fashioned way is probably a lot cheaper than cloning and genetic modification. I would think that ideally, you'd want to clone/modify a few and then breed them.

  7. Healthy by kamapuaa · · Score: 5, Interesting

    Worth mentioning that humans evolved to eat animals with standard fat percentages, not margarine or mealworm-sheep. There is no significant evidence for concluding that dietary saturated fat is associated with an increased risk of CHD or CVD, and there are healthy populations that traditionally go 6-9 months with no fats except animals fats.

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    1. Re:Healthy by slew · · Score: 3, Informative

      Worth mentioning that humans evolved to eat animals with standard fat percentages, not margarine or mealworm-sheep. There is no significant evidence for concluding that dietary saturated fat is associated with an increased risk of CHD or CVD, and there are healthy populations that traditionally go 6-9 months with no fats except animals fats.

      FWIW, the main advance with this announcement is not the omega-3/FAT-1 transgenic aspect, it is the new cloning technique BGI calls handmade cloning which apparently allows lower-tech facilities and higher transgenic clone yield. BGI has already done this transgenic modification with pigs and now they have done it with sheep. With this new cloning technique, however, it might be possible to do this at an industrial scale.

      However, If you are interested instead about this specific "fat-1" transgenic idea, it was done with mice way back in 2004.

      Although that is possibly true that saturated fats aren't corrolated with increased risk of CHD or CVD, omega-3 fatty acids are required for controlling blood clotting and building cell membranes in the brain and are assumed to be a necessary nutrient. The "healthy populations" you seem to be alluding to likley maintain their consumption of omega-3 fatty acids from seafood and nuts and oils for 6-9 months of the year.

    2. Re:Healthy by CAIMLAS · · Score: 4, Insightful

      Here in America, we also have processed grains in everything.

      We also have a very high percentage of our diets consist of processed GMO grains (corn, wheat). If you're having 2 hamburgers with a handful of corn chips and two white wheat buns, the meat isn't going to be the primary component of the meal.

      It seems that every couple months there's a news article about some old guy or gal who died after a fairly insignificant (not particularly active or sedentary, nothing really marked to note) life who spent their entire life having pork (ham/bacon) and eggs for breakfast every day. It wasn't until the inclusion of excess grains that Americans started to have issues in the late 1800s.

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    3. Re:Healthy by sunspot42 · · Score: 2

      >Except we didn't evolve to eat animals every day in large amounts.

      Oh really? So what were we eating for the million or so years the human race evolved prior to the invention of agriculture?

      Of course we ate meat. It was the only thing an animal our size with a digestive system like ours could eat. Any study of primitive, hunter-gatherer societies will show that meat, eggs, fish and insects are the primary component of the diet in pre-agricultural cultures. Nuts, seasonal fruits, a few starchy tubers and select vegetables typically make up the remainder of the diet.

      There are plenty of traditional societies where meat is the overwhelming component of the diet (Eskimos, for example). Invariably these people were incredibly healthy prior to the introduction of the modern western diet, with its abundance of cheap carbohydrates and processed oils. Which are garbage that humans aren't designed to eat.

  8. Re:"fat found in nuts, seeds, fish and greens" by ColdWetDog · · Score: 2

    Or cashews.

    Could be a growth market - flavored cows. Spinach cows, cashew cows, trout cows, kale cows.....

    Dunno.

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  9. What could go wrong? by jtotheh · · Score: 2

    I don't want to seem old or old fashioned but this seems like a really bad idea in numerous ways. Maybe they should feed the clone brains from another sheep to add another dubious aspect to this process.

    1. Re:What could go wrong? by siddesu · · Score: 2

      You're not scared enough. Just wait until the Chinese scientists get permission to do the breeding on that asteroid that Google is about to bring in Earth orbit. Anyway, I am off to stock up on some shotgun shells, plasma cells and rockets.

  10. Disgusting by doston · · Score: 2

    Not eating cloned anything or anything that's been screwed around with. I know it's unpopular here, but I eat everything organic...everything. As far as meat, if it didn't eat what it was supposed to eat; pasture raised and organic at that, I avoid it. Chickens eat bugs and grass, not feed. They like to scratch around in dirt, not hang out idly in cages all day. Same with Beef, less the bugs. We're likely evolved to eat a paleolithic era type diet. Going to stick as close to that as possible. You aren't just what you eat, you're also what your food ate. Why would I support something like 800 million pounds of pesticide being dumped on the land every year? Now it's some pesticide killing the bees. I remember when my Father's doctor had him eating trans-fat for his heart trouble. What will researchers discover ten years after this cloned junk's been foisted on the public?

  11. Re:Fat? by WarSpiteX · · Score: 3, Informative

    I think you may be wrong. Nuts and avocados are the most common plants to contain fats, but others do as well. Like olives.

    Unless you think you're frying your chicken on olive carbs, rather than olive oil?

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  12. Absolutely no information by CAIMLAS · · Score: 2

    There is absolutely no information in the article. "Healthy fat found in seeds"?

    What it sounds like they're doing is they've figured out how to genetically modify animals to produce omega 3 and similar types of fats instead of the fats commonly found in grain fed or industrially raised meats. That's actually fairly big (good) news, I think.

    On the other hand, 'healthy' fat can be found in animals which are 'free range'. It's less environmentally intensive. The unhealthy fat found in animal meat is only unhealthy because of the way they're raised.

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  13. Re:Fat? by jonnythan · · Score: 2, Funny

    Well obviously the fats came from animals. Olive trees are notorious for eating squirrels and other rodents.

  14. Evolution is far from perfection in some cases by doug141 · · Score: 2

    Worth mentioning that humans evolved to eat animals with standard fat percentages, not margarine or mealworm-sheep.

    Worth mentioning that humans evolved with recurved spines that cause back pain. Evolved eating, breathing and speaking out of the same hole. Evolved all kinds of stupid, non-optimized features, of which our fat intake/heart disease relationship may be another. "The Panda's Thumb," by Stephen Gould, is a good read. In one of the many essays, he argues that the panda's screwy thumb isn't some highly optimized limb for stripping bamboo, it's just what evolution has managed to give the panda to date, with the poorly-suited wristbone it had to work with.

  15. Sheep with roundworm fat? by __aaltlg1547 · · Score: 2

    Ewe!

  16. or, just eat "nuts, seeds, fish and leafy greens" by dAzED1 · · Score: 4, Insightful

    any particular reason one can't do this? A much more direct approach, healthier, more environmentally friendly, and doesn't have that extra-added danger of eating the product of extreme genetic modification...

  17. Re:Good fat, bad fat, I'm the guy with the gun by tbird81 · · Score: 2

    Food doesn't contain "good" or "bad" cholesterol. It's always good old (10R,13R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol (or C27H46O for short).

    Those terms refer to the way it is tested in the blood. Cholesterol travels around the body in little bubbles named after the proteins they're carried in. The low-density ones tend to be worse, because they deliver cholesterol to the tissues. If you just look at the total cholesterol in the blood, then you don't know if it's good or bad - nowadays labs will usually test which lipoproteins are carrying the cholesterol.

  18. Re:Fat? by dwpro · · Score: 2

    Agreed, I'm still hoping it's a joke.

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