Slashdot Mirror


Exposure to Wide Variety of Microbes May Reduce Allergies

sciencehabit writes "A new study reveals that people who grow up in more rural environments are less likely to develop allergies. The reason may be that environments rich with species harbor more friendly microbes, which colonize our bodies and protect against inflammatory disorders." From the article: "To test whether or not biodiversity does indeed create a shield against such conditions, the team investigated the microbial diversity of 118 teenagers. The study participants, who had lived in the same houses their whole lives, were chosen at random from a 100-by-150-kilometer block in eastern Finland. Some kids lived on rural, isolated farms, while others lived in larger towns. ... surveyed all of the types of plants growing around the adolescents' homes. The participants were part of a separate long-term allergy study, so the researchers took advantage of that data to investigate the connection between biodiversity and allergies. ... Whether there is just something special about Finland's native plants or whether this finding can be applied around the world is still an open question, Hanski says. 'Many research groups worldwide could easily attain these data from their study populations, and then we'd know how general these results might be.'"

33 of 120 comments (clear)

  1. People in rural areas by overbaud · · Score: 2, Insightful

    Are also less likely to come into contact with carcinogens in their food, air and water.

    --
    Users... the only thing keeping 1st level support from being the bottom feeders.
    1. Re:People in rural areas by bennomatic · · Score: 2

      I'm not sure that's true. Rural areas include things like mines and oil wells and the like, which could easily leak poisons into the groundwater.

      --
      The CB App. What's your 20?
    2. Re:People in rural areas by Mashiki · · Score: 5, Insightful

      Are also less likely to come into contact with carcinogens in their food, air and water.

      Load of freaking shit. Until I was born my family was a farming family for a few generations, I still have a few friends in the business. One who does cattle(milk) 15k head(family owned), and another that does rotational crops from soy, corn and hay, to more rare stuff like ginseng and hemp. Sorry, but you get exposed to all sorts of really, really nasty stuff. On the field, and at your dinner plate. Because honestly, you're buying exactly the same stuff more often than not that everyone else does.

      On the upside, you also get exposed to just about everything that nature can throw at you before it hits the slaughterhouse too. From cowpox to chicken based colds to whatever else. And you're not cooped up inside for 18hrs a day(unless it's winter), which really helps.

      --
      Om, nomnomnom...
    3. Re:People in rural areas by Charliemopps · · Score: 2

      Good point... but having had asthma for 20yrs now, I would gladly trade a disease that's made my entire life miserable for one that will simply kill me 10 years early.

  2. Again? by clickclickdrone · · Score: 4, Informative

    Hardly news, it's been reported many times over the last few years that research indicates our overly sterile environment is causing problems with alergies, asthsma etc. Heck, even our grandparanents knew this with old wives tales about eating dirt to make you healthy. A collegue from India tells me they have a ceremony involving putting some mud or something in a babies mouth to encourage a healthy defence mechanism.

    --
    I want a list of atrocities done in your name - Recoil
    1. Re:Again? by interkin3tic · · Score: 2

      I've heard that HYPOTHESIS before, but don't think I've heard it tested like this before. Anyway, scientific results should be replicated. And old wives tales and Indian ceremonies are poor bases for medicine.

    2. Re:Again? by sjames · · Score: 3, Insightful

      You'd be amazed how much medicine is "old doctor's tales" or the result of taking advertising claims at face value.

      At any rate, this particular set of "old wives tales" seems to be backed by modern scientific evidence, from the study in TFA and others.

    3. Re:Again? by Mattsson · · Score: 3, Interesting

      But this seems more focused on finding the mechanism behind why growing up in a "dirty" environment leads to fewer allergies.
      Possibly, this could lead to a "cure" for those growing up in unhealthy environments, like having overprotective parents, living in a large city or for other reasons being unable to have a healthy childhood environment.
      Maybe it is possible to develop something like those yoghurts with bacteria that helps people with an unhealthy or too sterile diet keep a working digestive system but for people who need something to keep them from developing allergies instead.

      --
      /.Mattsson - My native language is not English, so please don't whine over linguistic errors. (That's lame anyway...)
    4. Re:Again? by pev · · Score: 2

      Absolutely seconded. It's amazing what people believe. For example, in the the middle ages people used to believe that treating pussy wounds with bread with a blue mould would help. Such poppycock would be a preposterous basis (sic) for medicine.

    5. Re:Again? by JamesP · · Score: 2

      Yes, because the only observations that are true is what comes from a lab, right?

      Vaccines come from the exact kind of observation the parent mentions, sure it was tested.
      But of course, modern "web scientists" only consider "research" that comes from lab financed companies

      But if you want to test it, sure, go ahead, because obviously you know better than several years of immune system research

       

      --
      how long until /. fixes commenting on Chrome?
    6. Re:Again? by smooth+wombat · · Score: 3, Informative

      only that this study was far from conclusive.

      Fine, this study was not conclusive. How about we add in this study (2008), the same comment from the Mayo Clinic, this study (2012) or this one (2012).

      They all say the same thing: getting dirty as a kid and growing up in a rural environment reduces ones vulnerabilities to infections and afflictions. It's called the hygiene hypothesis and makes perfect sense when the evidence is examined.

      People, particularly kids, who grow in more sterile environments (constantly using hand sanitizers, over using antibiotics, keeping everything spotless) on the whole, have more allergies and other issues than those who don't go OCD or, if you prefer, Monk.

      Not sure how much more evidence you need when it's staring you in the face.

      --
      We will bankrupt ourselves in the vain search for absolute security. -- Dwight D. Eisenhower
  3. Interesting details to already studied subject by Anonymous Coward · · Score: 5, Informative

    It has already been shown that the children growing in "dirtier" surroundings develop less allergies: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868862/ . This study shows that there is a correlation between flora diversity near home and allergy rates with people growing up nearby each other.

  4. A common problem with target based incentives by samjam · · Score: 3, Insightful

    Clearly the human body sets strict targets for pathogens identified and the immune system is pushed to find enough pathogens, even finding subversive and insurgents among friendly substances, even in itself, if that is what is required to meet the targets.

    We see the same thing in the operation of government and security forces. We see similar bad behaviour as education and health systems struggle to meet centrally set targets and commence a path of undesirable behaviour in order to meet the target and obtain the incentive.

  5. Allergies are good, m'kay... by Anonymous Coward · · Score: 2, Interesting

    If you have allergies, it is a sign that your immune system is doing exactly what nature intended.
    People with allergies will very likely be less suscebtible to viruses, bacteria, fungi and protozoa.

    I have hayfever (allergy), my gf doesn't. She get's flue infections every year. I havn't had one in 4 years...

    http://news.yale.edu/2012/04/25/why-hay-fever-may-be-good-sign

    1. Re:Allergies are good, m'kay... by Theophany · · Score: 2

      I don't get 'flu infections and have no known allergies. Just generally eating what you should (i.e. fruit, vegetables) and drinking right (i.e. sufficient water every day) works a treat for me.

      Then again, I also drink enough alcohol on a weekly basis to ensure that my innards are sterile and no foreign life can subsist within me. Take that, gut bacteria.

  6. What a discovery... by Anonymous Coward · · Score: 2, Interesting

    When I was a child, I was spending weekends and summers in the countryside, eating dirt, ants and flowers, and for some "misterious" reason I was the only kid in my classroom who didn't have any allergy! When I had a kid myself, I was also taking him to the countryside regularly and now he's 26 and also 100% allergy-free. Genetics? I doubt it: his mother, raised 100% in city, is allergic to almost any known allergen out there! Also, discussing the matter with several friends, we noticed the same: take your kids to the Great Outdoors regularly, and they'll be allergy-free; keep them in the city, and expect them to spend springs looking like Rudolph, Santa's reindeer.

    1. Re:What a discovery... by DarwinSurvivor · · Score: 2

      And just to add to your argument, I did more camping as a kid than anyone I know and both me and my father share LOTS of environmental allergies. It's also been shown that prolonged exposure to certain things (like cut wood and cats) can *induce* allergies that were never present before.

  7. Child nurse by spectrokid · · Score: 2

    My sister is a child nurse who visits young families at their homes to give advice and check on the babies. The "lower classes" live of junk food and use cheap stuff, with plenty of cheap perfumes, insecticides and random chemical crap in their household. Their children suffer from obesity, and even vitamin deficiencies. But NEVER allergies. The rich families with cleaning ladies twice a week, bio-detergents and balanced organic diets however...

    I used to work for a factory which made a protein you could get allergic to, so the staff was closely monitored. We had lab technicians who did DNA analyses on nanograms of the stuff, and factory operators who were swimming in tons of the crap. Guess where most allergies occured...

    --

    10 ?"Hello World" life was simple then

  8. Could very well be junk science... by KrazyDave · · Score: 2

    for the reasons cited in other posts, plus the demographics of city dwellers would be different. Could be that urbanites would include poorer (weaker immune systems from lesser pre and post-natal health, poor diets, more crowding/exposure to communicable diseases) people, as well as "nerd" professionals who seem to have a higher incidence of physical limitations (poor eyesight, sedentary jobs, weak constitutions) and thus not really be an element of environmental exposures. Just demographics.

    --
    www.chihuahuarescue.com- Help to end dog abuse, abandonment and cruelty
  9. Re:Hrumph. by Hognoxious · · Score: 4, Insightful

    If only there was some kind of compromise position - let's call it a "happy medium" - between living in hermetic sterility and getting cholera.

    --
    Confucius say, "Find worm in apple - bad. Find half a worm - worse."
  10. Fight allergies by *exposing* yourself by Hamsterdan · · Score: 4, Interesting

    That's how I cured my cat allergies. I couldn't even stand to see a picture of one. So I got one... It was hell for a couple of weeks. Now, 16 years later, no reaction whatsoever unless she scratches or bites me. Even other cats have almost no effect on me now. If you always sterilize, remove germs and ultra-clean everything, of course your body won't know what to fight.

    --
    I've got better things to do tonight than die.
    1. Re:Fight allergies by *exposing* yourself by Maow · · Score: 2

      I'm glad it worked for you, but it seems I'm in a different situation.

      Have done a fair bit of gardening over the past decade, no problems.

      Got a dog 5 or 6 years ago, seemed to have developed an allergy where my hands would bubble, split, crack, peel; it was insanely itchy, then painful. Used to joke that plunging them into boiling water would at least slough off the damned skin that was tormenting me and be only incrementally more painful.

      Once the dog passed away, I figured the allergies were a thing of the past. Wrong! They became so bad I could hardly walk.

      This spring things were pretty good - until I began weeding. Over one weekend set in a reaction that lasted a month, only cured with prednisone.

      Then, this sunday I was out weeding again, wearing gloves 99% of the time, and by monday morning I was so terribly itchy & sore that when scratching my hands came away wet with ... seeping yuck from the "wounds".

      I'm frankly fucking terrified now of further exposure as it's a crippling effect, similar to fleas plus a very bad sunburn.

      I don't know what to do - gardening is one of my only enjoyable pass times, yet I don't think I can expose myself any more and go through months of the side effects. Fortunately don't seem allergic to eating the produce...

      Oh, and haven't been too sterile about things - been a fairly avid camper over the past 10 years too.

      As it is now, it's 5:35 and I'm waiting for a medical clinic to open to either get my 2nd prednisone prescription in a month, or to get a "shot" for allergies.

      God damn it, I'm in some pain right now.

      I heard an interview with the "hook-worms from latrine in Cameroon" guy, was disgusted. I can now almost see his point. Almost.

  11. Re:Hrumph. by sjames · · Score: 3, Insightful

    The risk/benefit seems to strongly favor water purification, but it seems we are going too far in other things these days. It's likely a natural outcome of the pervasive free floating fear in our culture today.

  12. Re:Hrumph. by Samantha+Wright · · Score: 3, Interesting

    There is! We call it the big blue room. Some people say it has no ceiling. I scoff at them.

    ...personally, I vote for mandatory rural daycare, followed by kindergarten in an industrial district, and so on. By retirement you may live in a glass bubble.

    --
    Bio questions? Ask me to start a Q&A journal. Computer analogies available for most topics!
  13. Re:Explains by sjames · · Score: 5, Insightful

    Nonsense. We have not had medicine (that works) long enough to see a significant effect from natural selection.

    Most of the problems are a result of our culture of fear and wrapping children in a protective cocoon. It is proven, for example that prenatal exposure to peanut proteans helps to prevent peanut allergies. As a result of mothers in the U.K. following bad advice and avoiding all peanut products during their pregnancy, there was an explosion of peanut allergies.

    Meanwhile, the strategy of total avoidance of anything that provokes even the slightest reaction has lead to a lot of mild allergies never being desensitized.

    Meanwhile, most allergies are of the minor itching or redness sort, not the OMG where is the epi-pen type, but you'd never know it from the media reports.

  14. My anecdote by Nidi62 · · Score: 4, Interesting
    For the record I'm still pretty young, only 25. But I grew up playing in the dirt, playing sports (especially football and baseball). I usually got dirty every day. If I got a cut, I rarely used a bandaid, even more rarely used something like neosporin. My house didn't use a lot of disinfectants, and my sister was the same way I was. I still don't really wash out or clean out cuts and they never get infected (and with where I work, the amount of dirt, oil, and other things I get on me is crazy), I rarely get sick, and I have no allergies. My sister rarely gets sick, and the only allergy she has is to pollen (which is a really common allergy here in Georgia). I firmly believe it was my lifestyle growing up that kept my immune system so strong.

    And yes, I am aware that the plural of anecdote is not data.

    --
    The only thing necessary for evil to triumph is for it to be pitted against a slightly greater evil
  15. Re:Explains by Anonymous Coward · · Score: 4, Interesting

    Really? Given that infant mortality has gone from several a generation to several generations per occurance in families, are you really sure that we don't see a substantial change in the population? While the gene pool is unlikely to change substantially in a few generations, the number of people who are living with genetic defects in the western world has increased immensely. Start with the extreme examples. People born with Down's syndrome didn't survive very long 100 years ago. People with cystic fibrosis didn't generally survive very long 100 years ago. Babies with GI troubles "failed to thrive" and died. Just because no major "evolution" has occured doesn't mean that the population is ithe same as a century ago.

  16. Re:Explains by Gr8Apes · · Score: 2

    If I only had mod points. Anyone that thinks we haven't had more significant changes over the past 5-8 generations than the last 30000 years with the exception of a few major plagues is smoking something.

    --
    The cesspool just got a check and balance.
  17. Until I moved overseas by arcite · · Score: 3, Interesting

    I was allergic to all kinds of nuts. I have lived all over Africa and no doubt been exposed to countless microbes, I am now allergy free. Pistachios used to be the worst, I couldn't even lick them or my throat would swell up. I now eat them by the bag. There is truth to this, our immune systems were not meant to be exposed to an environment soaked in bleach and disinfectant.

  18. about time... by mallydobb · · Score: 2

    I think a lot of this is "provable" with anecdotal evidence, but I think there is something about allowing people to get sick or exposed to germs...we live in a world where people are afraid of germs and sickness and want to drop an antibiotic at the first sign of illness, bacterial or not. I currently live in a country where antibiotics can be gotten at pharmacies without a prescription. When people start to cough or otherwise display symptoms of being sick the first recourse is an antibiotic; doctors even will prescribe antibiotics when the symptoms point towards virus, just to make induce a placebo effect and make sure their patient feels cared for.

    Anecdotal evidence...I grew up in the country and was exposed to a lot of "pathogens". My mother was a school nurse (likely bringing some of her work home with her) and just being outside in the woods, going to the bathroom, climbing trees, swimming, stick fighting, making forts, etc...all without washing hands. I never had allergies as a child and the only time I get sick in Beirut is when I am exposed to an extreme amount of pollution or the strange pollen from the pine trees here that plagues nearly everyone about once a year. I am even tolerant of something called the spring worm (caterpillar) that has feces and body hairs that are extremely irritating.

    Our bodies are stronger than we give them credit for and we need to stop being a nation/world of hypochondriacs. Its nice that there seems to be some serious study on this issue. From personal experience I seem to see that the people who are the sickest are those that were sheltered the most growing up.

    --
    --- b2b.mallaidh.org | www.mallaidh.org | www.kidsalive.org/article/kahlil-pfaff/
  19. Dogs by Barbara,+not+Barbie · · Score: 3, Interesting

    I used to have hay fever, pollen fever, even pollen from trees - kleenex wasn't enough - I'd go through rolls of paper towels, gobs of dristdan nasal spray, lots of anti-histamines, unable to sleep because I couldn't breathe ... nothing really worked.

    I was also allergic to dogs and cats - so I got a dog. Two months of absolute hell, 24/7, because he went with me everywhere ... then one day, it all just stopped. It's been almost two decades with no allergies to dogs, most cats (there was one who could stillmake my eyes water, for some reason) ... no hay fever or pollen allergies whatsoever ...

    Our systems evolved in an environment where they have to distinguish between pathogens that can harm you, and the innocuous stuff like pollen. They aren't all that good at doing the job when there aren't any nasties to "train" against.

    --
    Let's call it what it is, Anti-Social Media.
  20. Reverse Causation by dorpus · · Score: 3, Informative

    These observational studies did not establish the direction of causation (assuming it is causal). It could be that people who do not have allergies are attracted to (or remain) in farming, while those who are allergic take jobs in the city. I did a report on this in grad school.

  21. Re:Hrumph. by sjames · · Score: 2

    AH! The dreaded phobophobia. We've tried to study that for years, but every time we attempt to recruit a patient they run away. Well, there was that one guy who quacked like a duck, but it turns out he was choking on a kazoo.