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Rewiring the Autistic Brain

sciencehabit writes "Signs of autism — such as impaired social skills and repetitive, ritualistic movements — usually begin to appear when a child is about 18 months old. Autism is thought to result from miswired connections in the developing brain, and many experts believe that therapies must begin during a 'critical window,' before the faulty circuits become fixed in place. But a new study (abstract) shows that at least one malfunctioning circuit can be repaired after that window closes, holding out hope that in some forms of autism, abnormal circuits in the brain can be corrected even after their development is complete."

139 comments

  1. But, but... by Anonymous Coward · · Score: 2, Funny

    Who will write our file systems??

  2. Anyone else insulted by this? by Anonymous Coward · · Score: 1, Informative

    Most symptoms of an ASD can be patched over with a little studying & practice & I know this from experience.

  3. Let's fix them all! by BenoitRen · · Score: 4, Insightful

    Great, now we'll be able to fix all of them! We really need that! /sarcasm

    I for one find this very offensive. It's like telling all autistics they're malfunctioning.

    1. Re:Let's fix them all! by Anonymous Coward · · Score: 2, Insightful

      I'm unhappy with my intellectual abilities and I have a PhD and no mental issues. If someone could fix me to make me smarter, that sounds great. So I'm not sure what you are getting at. Why wouldn't many autistics like to have improved mental functioning, when many normal people do too? In any case yes, autistics are malfunctioning. You may find that offensive in the same way that I find it offensive that my body is set to malfunction within 100 years. Unfortunately facts don't become false just because they are offensive.

    2. Re:Let's fix them all! by Anonymous Coward · · Score: 3, Insightful

      Preface: I'm diagnosed with asperger's, a form of high-functioning autism, and I do a lot of work relating to autism advocacy.

      That being said, the language might need a little work, but we don't try to pretend a person with a deformed arm doesn't have a deformed arm. People on the autism spectrum tend to have a variety of physical issues relating to gut bacteria, mitochondrial function, nutritional levels and other things. Many of these issues can also be seen in their mothers, and there's some strong correlation between certain nutritional levels in the mother and the incidence of autism. There's really no question that autism has a physical element. It's somewhat disingenuous to try to talk as if autism isn't a "malfunction" in the human body.

      If someone is missing a leg, and goes on to lead a normal life anyway, you don't pretend like it never happened, you stand proud of them for overcoming it. If you want to support those on the spectrum, be proud of those who accept that there's something malfunctioning in their body and find a way to make life work despite that. Don't try to pretend like there's nothing malfunctioning, because the first message that sends is "if you can't do it, it's all your fault" and you'd never tell that to a person who couldn't walk because they had a deformed leg.

    3. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      Great, now we'll be able to fix all of them! We really need that! /sarcasm

      I for one find this very offensive. It's like telling all autistics they're malfunctioning.

      They are. Just as much as a diabetic, hypoglycemic, or any other individual with a disease. They're body is not performing within acceptable levels of "normal," and if there is something that can be done to return them to baseline, then it's probably a good thing.

    4. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      Now see, that's offensive (to the people actually diagnosed with Autism). Even as a joke it's trivializing a real condition.

    5. Re:Let's fix them all! by Earl_Parvisjam · · Score: 1, Insightful

      WTF are you talking about? Do you have any idea what autism is or are you just making crap up? Here's a hint, Autism isn't ADD. Cripes, it's bad enough some people think it's caused by vaccinations without this sort of uninformed blather.

    6. Re:Let's fix them all! by TemperedAlchemist · · Score: 5, Insightful

      We are, in a way. But you know what's to be said about judging a fish on its ability to climb a tree. Only we're like monkeys that have difficulty learning how to climb trees, and perhaps more importantly, don't like climbing trees even if we do learn.

      Should we learn how to climb trees? Definitely, you don't know when you might need to climb a tree as a monkey. But perhaps not all monkeys have to climb trees to be monkeys. Maybe they're perfectly happy on the ground using sticks to eat bugs. Not liking climbing trees (and being absolutely terrible at it) shouldn't mean there's something wrong that needs to be corrected.

      And think of all the things the ground monkey can explore. On the ground there are rivers to play in and lots more space than up in the trees. And maybe that's what the monkey community needs, monkeys that can find nice fresh sources of water on the ground or somewhere to bathe as well as monkeys that enjoy living their whole lives in trees eating fruit and swinging around.

    7. Re:Let's fix them all! by Anonymous Coward · · Score: 3, Insightful

      The tone is offensive yes, but I can entirely understand the motivation to help those with low-function autism live more normal lives. However, being HFA myself, I'm not certain I'd want to be "fixed" at this point. I wouldn't be myself, and I've grown to accept who I am.

      However, growing up without some of the social and emotional problems I have faced would have been much more pleasant, and it makes perfect sense why a parent might want to help keep a child from going through it. And for LFA things can be much, much worse.

    8. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      I get the analogy but it doesn't stop there... My nephew who has autism /asperges will only eat white bread, mc Donaldson chicken nugget meals n popcorn chicken nugget meals n saos needless to say that's a terrible diet and as he gets older it will take its toll n probably lead to a lower life expectancy. So Yeh any improvement in treating autism even if he lost his amazing artistic ability. Although obviously it's a spectrum n some autistic people will eat more normally

    9. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      Don't try to pretend like there's nothing malfunctioning, because the first message that sends is "if you can't do it, it's all your fault" and you'd never tell that to a person who couldn't walk because they had a deformed leg.

      Wouldn't I?

      This is the internet; you have no idea how big an asshole I am IRL.

    10. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      I get the analogy but it doesn't stop there... My nephew who has autism /asperges will only eat white bread, mc Donaldson chicken nugget meals n popcorn chicken nugget meals n saos needless to say that's a terrible diet and as he gets older it will take its toll n probably lead to a lower life expectancy. So Yeh any improvement in treating autism even if he lost his amazing artistic ability. Although obviously it's a spectrum n some autistic people will eat more normally

      Yeah... I'm autistic and I used to have exactly the same diet when I was about 4 (I think?). My parents put their foot down, and now I'll eat just about anything. Even if it is caused by an obsession (which it doesn't sound like it is, in my uninformed opinion), you can still un-learn bad habits. People aren't defined solely by their mental disorders.

    11. Re:Let's fix them all! by Anonymous Coward · · Score: 1

      Don't try to pretend like there's nothing malfunctioning, because the first message that sends is "if you can't do it, it's all your fault" and you'd never tell that to a person who couldn't walk because they had a deformed leg.

      Wouldn't I?

      This is the internet; you have no idea how big an asshole I am IRL.

      I've a pretty good idea.

    12. Re:Let's fix them all! by Anonymous Coward · · Score: 1

      " In any case yes, autistics are malfunctioning."

      You mean like the warmongering, wage caste loving, profiteering, superstitious, corrupt, law abusing "normal people"? We could make an excellent case that normality is just popular malfunctioning.

    13. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      You might not want to be able to interact with other people better, but I would. It's not offensive.

    14. Re:Let's fix them all! by postbigbang · · Score: 1

      The fight between "neurotypicals" and those within the ASD spectrum will be ongoing. Don't absolve ASD members of the problem with most of the problems you mention, caused by another disorder: sociopathy, and narcissism.

      --
      ---- Teach Peace. It's Cheaper Than War.
    15. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      Everyone has mental issues.

      Being unaware of them is rarely an indication of their insignificance.

      If you rewire my brain, it may leave a person who functions in the way that others find desirable, but who it does not leave is me.

      Also, please don't assume that the fact that I lack social intuition means I lack intelligence, and also don't assume that I think that you having a PhD makes me presuppose your intelligence to be greater than mine or even just greater than average. I spontaneously taught myself to read college-level books and to do math. When I was in school, I would get into arguments with teachers about subjects, and I never lost. When I was three years old I could remember entire books word-for-word and repeat them. I also taught myself how to do my profession, and have been asked by several others if I have a PhD in the subject. No, autistic brains just work by learning every detail about whatever subjects they find interest in, and their knowledge thereof often exceeds all but the highest experts.

      I have had to memorize social behaviors to be successful in work. I am not social. But I don't need to be "fixed".

    16. Re:Let's fix them all! by TemperedAlchemist · · Score: 1

      Well I can't speak for others, but caffeine does help "treat" my condition. I grow more comfortable socially and it's easier.

      But that's not necessarily fixing anything, just removing a bit social anxiety doesn't mean I small talk with the best of them. I still don't understand people or social nuance with caffeine, it just makes me more willing to passionately rabble on about something that fascinates me. Ask me about the weather and I'll probably start talking about cloud seeding or cosmic rays contributing to more cloud cover.

      I'll probably make a great professor someday.

    17. Re:Let's fix them all! by Anonymous Coward · · Score: 1

      My autistic son is aggressive, self injurious, and nonverbal. Nice that _you_ are offended by the possibility his life could be improved.

    18. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      Ah, and you are the one who gets to define "normal" I take it?

    19. Re:Let's fix them all! by JoeMerchant · · Score: 4, Insightful

      Define improved.

      If you gain social intelligence at the cost of creativity, have you been improved?

      If you can suddenly understand the opposite sex and get them to sleep with you quickly, but no longer do basic math in your head, is that a good trade?

      Problem with brain re-wiring is that you won't often "unlock a secret room full of new abilities", more often you'll open a new processing section that needs training and demands resources from other functions.

    20. Re:Let's fix them all! by JoeMerchant · · Score: 1

      With 1/50 male children being diagnosed "on the Autisim spectrum," the category catches a wide variety of people these days, with a lot of variation in social and abstract intellectual functioning.

    21. Re:Let's fix them all! by JoeMerchant · · Score: 1

      Alcohol also removes the social inhibition - regardless of neurotype.

    22. Re:Let's fix them all! by CODiNE · · Score: 1

      I've spent years slowly learning how to eat brussel sprouts, mushrooms, mayo, mustard, cooked carrots, shrimp, calimari... those aren't really big deals but damn if I'll ever like eggs! Working on that for the last 3 years and I just hate em. It's the texture... like chewing on snot or something. At least I can tolerate them once in a while and won't starve if I'm stuck somewhere with scrambled eggs for breakfast.

      --
      Cwm, fjord-bank glyphs vext quiz
    23. Re:Let's fix them all! by macraig · · Score: 1

      I wish I had mod points handy right now. +1 Insightful

    24. Re:Let's fix them all! by Tablizer · · Score: 1

      and it frees up their hands so that monkeys can clobber other monkeys with sticks and stones

    25. Re:Let's fix them all! by sjames · · Score: 2

      Would you be as anxious for the treatment if it was likely to alter your personality and might leave you unable to understand your own doctoral thesis?

      The higher functioning autists might indeed opt-out of such a treatment. It's hard to say what the more withdrawn autists would think of it.

    26. Re:Let's fix them all! by macraig · · Score: 1

      You know what you're describing, don't you? It's the beginning of a speciation event, one based not on physical incompatibilities but behavioral and cognitive ones. It's happened to primates before.

      I'd have settled for a +1 Insightful, but my modpoints wallet is empty.

    27. Re:Let's fix them all! by sjames · · Score: 1

      If someone is missing a leg, and goes on to lead a normal life anyway, you don't pretend like it never happened, you stand proud of them for overcoming it. If you want to support those on the spectrum, be proud of those who accept that there's something malfunctioning in their body and find a way to make life work despite that. Don't try to pretend like there's nothing malfunctioning, because the first message that sends is "if you can't do it, it's all your fault" and you'd never tell that to a person who couldn't walk because they had a deformed leg.

      By the same token, you wouldn't insist that they give up their prosthetic in favor of a more normal looking but potentially less useful transplanted leg. You might offer that choice.

    28. Re:Let's fix them all! by sjames · · Score: 1

      A lot of kids are like that at 4, autistic or not.

    29. Re:Let's fix them all! by memnock · · Score: 1

      I just found out about an alternative hypothesis to the cause of autism: inflammation in the pregnant mother. Apparently an immune disorder in a mother will affect the unborn child.

      https://www.nytimes.com/2012/08/26/opinion/sunday/immune-disorders-and-autism.html?_r=2&pagewanted=all

      I didn't read any further on the topic, but the article does reference at least one researcher, so one could see what kind of study has been performed to support this idea.

    30. Re:Let's fix them all! by Anonymous Coward · · Score: 1

      I was pretty hardcore as a child about eating only specific things, but my mom made it a hundred times worse than it had to be by trying to force me to eat things (and worse, eat large quantities of things that were forced upon me). My willingness to try other foods didn't really thaw until I was in college & could try food in the cafeteria with zero risk of having to eat something I didn't like. There are still certain foods that the mere sight of is enough to put me at risk of throwing up, in no small part thanks to my mom force-feeding them to me as a child.

      Neurotypicals rarely understand, but to an Aspie child, force-feeding is basically rape. Maybe worse. At least rapists don't feel entitled to beat you afterwards for crying or throwing up after they force disgusting objects into your body.

    31. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      Nope, some see the "duality" of US politics as all right wing. Only difference is moderately right wing or way out in the fog.

    32. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      Or terrible, depending on the students attending.

    33. Re:Let's fix them all! by ultranova · · Score: 1

      By the same token, you wouldn't insist that they give up their prosthetic in favor of a more normal looking but potentially less useful transplanted leg.

      Are you referring to the monkey brain prosthetics two stories up from this one, or is this yet another example of Just World Fallacy (you couldn't possibly just be shafted, so every problem you got saddled with must have some kind of at-least-equal payback)?

      You might offer that choice.

      This, actually, rises a question: as our knowledge of brain increases, at what point do we stop needing consent from misworking circuits to apply repairs? Probably not at autistics, but should we listen to the protests of a sociopath who insists that he doesn't want to feel empathy (but will almost certainly go on to harm lots of people if not cured)? How about a crazy religious fanatic? Or even anyone with any kind of religious beliefs at all - they're enemies of reason, after all? Or shall we go another route and cure atheists of their childish need to rebel against clear and obvious gospel truth, whatever that might be? A republican (or anyone you disagree with politically)? A drug addict? A delusional paranoid? An anti-vaccination activist?

      This whole thing is opening a huge can of worms, and since people still sometimes publicly defend eugenics (of the forced sterilization of people they consider inferior variety) even on Slashdot, I'm not at all certain humanity can handle it in a way that won't turn into a horror movie very fast.

      --

      Forget magic. Any technology distinguishable from divine power is insufficiently advanced.

    34. Re:Let's fix them all! by artor3 · · Score: 3, Insightful

      Correlation is not causation. A fraction of autistic people (10%) are naturally gifted at math or creativity, but that doesn't mean that autism causes that talent. It is quite possible that the genetic causes for autism ALSO cause savant syndrome, and that we could cure the former without touching the latter. Even if not, we could cure the 90+% that don't get any benefit from their autism, and leave the savants untouched

    35. Re:Let's fix them all! by sjames · · Score: 1

      What part of LEG sounds like monkey brain prosthetic? :-)

      But no, it's not a just world fallacy, it's just a matter that disruptive changes to a person in adulthood can be devastating even if it seems 'obvious' that it should be a good thing. People blind from early childhood or birth who have their vision 'fixed' as adults rarely get much use from their new vision but have been known to commit suicide. I can't imagine that having such a thing forced upon them would be a good idea.

      Likewise it may seem to us like a transplanted leg would be superior to a prosthetic. It may BE superior for someone who has just lost their leg. In practice, it might be a liability for someone who is already well adapted to their prosthetic. It's not as if they'll hop off the surgical table and go for a jog.They may even go from Olympic contender to barely managing to limp with a cane.

      As for the rest, that is a big part of why I say it may be offered but not insisted upon. It is a huge can of worms. Lets just say I have zero confidence in our legislators or judges to make the right call there if we allow for ANY compulsory treatments.

      In the case of the sociopath, they don't have to be cured if they don't want to be, but at the same time society is not obligated to allow a sociopath to harm others.

    36. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      > Autism isn't ADD.

      Correct, but approximately 1/3 to 1/2 of Aspies DO have symtoms that more or less totally overlap with the symptoms of "inattentive" ADD. So many and so completely, in fact, that there's controversy over whether "inattentive" ADD is a variant of ADHD that neutralizes some of the otherwise-debilitating conditions of AS, or a completely different condition that simply represents the mildest form of ASD and has symptoms that coincidentally overlap with ADHD.

      One easy way to recognize members of this group: they can often be described as "swashbuckling introverts" -- individuals who can feign neurotypicality -- sometimes, quite well -- but get drained and fatigued by it. Especially when younger, they crave attention, fame, and admiration... then feel crushed and violated by it when it actually happens.

      For many aspies, this is their first real encounter with depression... the devastating chapter in their lives when it really sinks in that their new, recent, well-rehearsed "normalcy" was all an act, and that no matter how good they might become at acting... it's always going to BE just an act. A really fatiguing act, at that.

      Face-blindness is common among this group -- they have a hard time recognizing people by face, especially when they see them "out of context". A few young aspies decide to do porn on the rationale that nobody will recognize them with their clothes on in other contexts... then learn the hard way that others DO, in fact, easily recognize people's faces, including those of fully-clothed former porn stars who now teach elementary school.

    37. Re:Let's fix them all! by ahabswhale · · Score: 0

      They are.

      --
      Are agnostics skeptical of unicorns too?
    38. Re:Let's fix them all! by Immerman · · Score: 1

      That of course presumes that savants could be detected during the critical window (however large it may be), and that parents would rather have a savant than a child that they can readily relate to.

      --
      --- Most topics have many sides worth arguing, allow me to take one opposite you.
    39. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      Great, now we'll be able to fix all of them! We really need that! /sarcasm

      I for one find this very offensive. It's like telling all autistics they're malfunctioning.

      As someone born with autism I agree - this is incredibly offensive. Anyone that seriously considers this an option deserves to be shot - whether something survives or not, rewiring a brain is murder.

    40. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      The tone is offensive yes, but I can entirely understand the motivation to help those with low-function autism live more normal lives.

      Drugging, segregating or genetically altering a child to make it fit a standardized configuration is not an acceptable solution when it entails fundamentally changing who they are. Autism isn't like schizophrenia - we are born with it, it can't be removed without destroying us as it is at the core of how we perceive the world and choose to interact with it. This is the reason that even after learning to socialize, most of us do not choose to do so beyond what is required to survive in society. The aspects of the trait perceived as negative can be negated with parenting that focuses on nurturing what a child is good at and teaching them they can attain what they want through interactions with society. The benefits after a proper upbringing far outweigh any perceived negatives, even as outsiders perceive them to exist.

    41. Re:Let's fix them all! by HideyoshiJP · · Score: 1

      I would say that would be entirely up to the person in question to define "improved."

    42. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      Stop blaming Bill, Steve.

    43. Re:Let's fix them all! by electrosoccertux · · Score: 1

      so, you'd rather do basic math in your head than sleep with hotties?
      what are you, gay?

    44. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      > so, you'd rather do basic math in your head than sleep with hotties? what are you, gay?

      If he were gay, he could do math (basic, complex, or otherwise) in his head, and STILL sleep with hotties.

      For gay guys, AS isn't a major impediment to having sex. Women impose harsh demands of social reciprocity and emotional connection. Men only care whether you're likely to be more fun than jacking off to porn (and if both guys are horny, but not really into each other, having sex TO porn is a possibility as well).

    45. Re:Let's fix them all! by BenoitRen · · Score: 1

      The problem I have with this reasoning is that, apart from not being able to relate to others well, autism is mainly a problem because of societal norms. As such I don't think they're malfunctioning, but different from most people.

    46. Re:Let's fix them all! by ultranova · · Score: 1

      What part of LEG sounds like monkey brain prosthetic? :-)

      The part where you bring up a prostethic leg in the context of repairing an alleged brain malfunction when there's another story about correcting brain malfunction (induced by cocaine) on monkeys with a brain prosthethic near this.

      Likewise it may seem to us like a transplanted leg would be superior to a prosthetic. It may BE superior for someone who has just lost their leg. In practice, it might be a liability for someone who is already well adapted to their prosthetic. It's not as if they'll hop off the surgical table and go for a jog.They may even go from Olympic contender to barely managing to limp with a cane.

      Ah yes, I see. You were talking about the usefulness to a particular person who knows how to use a prosthethic but not a "real" leg, while I was thinking about the usefulness of prosthethics vs. meat & bone legs in general. My apologies.

      As for the rest, that is a big part of why I say it may be offered but not insisted upon. It is a huge can of worms. Lets just say I have zero confidence in our legislators or judges to make the right call there if we allow for ANY compulsory treatments.

      So... sucks for anyone who happens to get paranoid delusions?

      It's not that I disagree with you, it's just that I don't think not allowing any compulsory treatments will really do much more than screw people over another way. I'm not sure there is a good solution to this problem. Nobody can be trusted with this power, yet the potential benefits of understanding how brains work are too great to leave well enough alone.

      Also, if you really understand how someone's brain works, you'd presumably be able to figure out inputs that alter their internal state so that they'll to accept the treatment, no matter what their reaction to a simple question might normally be. Does that count as coercion? Because while you're free from forceful coercion, the end result is nonetheless that you can not refuse the offer.

      In the case of the sociopath, they don't have to be cured if they don't want to be, but at the same time society is not obligated to allow a sociopath to harm others.

      I really don't see how the society can prevent them, unless we start punishing (imprisonment, socipath registry, do-not-fly list...) people simply for being sociopaths (or perverts, or communists, or atheists, or whatever), and if we do, well... that can of worms is now the Dune edition.

      --

      Forget magic. Any technology distinguishable from divine power is insufficiently advanced.

    47. Re:Let's fix them all! by sjames · · Score: 1

      Actually the AC I replied to is the one who brought up leg, I just replied to the example as given.

      I do understand that mental illness presents a special challenge. The condition itself may cause the person to make bad decisions about treatment. Of course, even calling it a bad decision is a bit of hubris since I have never had the condition nor do I have personal subjective knowledge of what it feels like to be treated. Some claim it's quite the horror and consider it worse than the disease (even when they're in remission). Others see it as a godsend. Meanwhile many mental health professionals consider sitting quietly to be a successful outcome (even when the average person would describe the patient as zombie like).

      Meanwhile, in the old Soviet Union where psychiatry was far more advanced than in the West, they discovered 'sluggish schizophrenia' and treated it aggressively for the good of the patient. It primarily strikes the well educated and presents with questioning socialist doctrine. The best treatment is high dose neuroleptics and confinement in Siberia.

      At least until we develop more wisdom and treatments that are preferred to the disease by most of the patients, I'd say we had best stick with "First do no harm".

      As for the sociopath, if they have actually committed a crime we have considerable latitude in how to treat them. We cannot ethically coerce a psychiatric treatment, but non-punitive custody can be mandated (much like quarantine but hopefully under better conditions). The condition also has bearing on aptitude. A business that puts an untreated sociopath in charge of others creates a huge liability for itself once awareness of the prevalence and nuances of sociopathy becomes more common.

    48. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      Suggestion: try stim meds, possibly augmented by a VERY low dose of a sedating TCA (like nortriptyline). Say, 36mg Concerta in the morning, 5mg IR methylphenidate ~10 hours later, and 10mg nortriptyline before bed. If he seems insomniac, try giving the IR methylphenidate ~2.5-3 hours before bedtime (most insomnia blamed on stim meds is actually caused by the stim meds completely wearing off, and self-induced adrenaline kicking in to compensate. Time the meds to wear off right at bedtime, and the problem goes away).

      Your child feels like he's constantly being assaulted and pulled in every direction. The methylphenidate will help him to focus and take control of his immediate environment (neutralizing the panic, stress, and anxiety). The TCA will smooth out the methylphenidate's metabolization a bit, and its mild sedating effects will take the raw edge off of the methylphenidate that he'd otherwise experience. It's a very good combination that literally took years for me to find.

      The aggression will probably start out by getting worse, but will eventually get better as he comes to realize that it's unnecessary. Ditto, for the self-injury. In his current state, his environment is intolerable. People with ASD can't tolerate the intolerable, and he's desperately doing anything he can think of to remove the stress and chaos around him. Self-injury won't work, but it gives him comfort by briefly enabling him to feel like he's able to exercise some tiny bit of control over his surroundings and environment.

      He's nonverbal because the cacophony of sounds around him seems to be totally random. He's never made the cause-effect correlation between sound, speech, and benefits. He hears a sound you'd interpret as "dinner", and if he associates it with anything, it's associated with being forcibly moved into a bright, noisy room with lots of people trying to shove things into his mouth.

      The meds aren't magic. They won't fix his problems overnight. They might even briefly make them appear to be worse (because he'll still react the way he always has, but might react more forcefully until it sinks in that he can dial down the intensity by a few notches). What they WILL do is put him into a state where he can start to feel in control, and begin to develop in a more normal manner.

      The most important thing to remember: ASD and ADHD might or might not share the same biological underpinnings, but they DO tend to benefit the same way from the right combination of meds. Sedatives & antipsychotics alone are probably the *worst* thing you can give someone with ASD, because they make the underlying problem WORSE, even if they're able to more effectively mask the overt public symptoms. Think about how you feel when you're stressed out and sleep-deprived, then imagine how much *worse* things would be if you took benadryl & had to remain awake. Your final reserve of strength would be ripped away, and you'd go berserk.

      Always remember: an aspie who feels like his environment is out of control will do just about anything to feel like he has some meaningful influence over it. If you felt dazed and dizzy, you might hit your head too in a desperate effort to make the dizziness go away. The solution isn't to immobilize your head so it can't be hit, or take sedatives so you'll be too sleepy to even try... the solution (or at least part of it) is to make the dazed dizziness go away, or at least get a little better. Which is exactly what stim meds do.

      Finally, when doing research, don't get too hung up on the word "antidepressant", and don't get hung up on the fact that TCAs are "old" and rarely used for treating *depression* anymore. There's abundant new research suggesting that TCAs synergize with stimulant meds for patients with ASD in ways that newer drugs -- alone, or in combination -- simply don't.

    49. Re:Let's fix them all! by sjames · · Score: 1

      Really, like the condition itself, there seems to be a spectrum. At one end there are people who are only diagnosed in adulthood if ever. On the other are people who don't appear connected enough to the world to survive at all without considerable assistance. In the middle are those who clearly don't connect very well socially but would obviously get along just fine if society could be a bit less militant about it's 'norms'.

      As to where the 'malfunction' line lies, that is a hard question as is usual for this sort of thing.

    50. Re:Let's fix them all! by JoeMerchant · · Score: 2

      Nice thought, but hard (and unfair) to put such decisions on young kids. My parents included me in the decision to skip 2nd grade, in retrospect it was probably the biggest and most painful mistake of my life, but it sounded great at the time. I had just turned seven.

      Many of these more radical interventions are being proposed for kids that are 2.

    51. Re:Let's fix them all! by HideyoshiJP · · Score: 1

      Very true. I think that comes with any big decision like that though. I was thinking more of a relative that was "diagnosed" with high functioning autism when he was in his teens (scare quotes because I believe HFA isn't an actual diagnosis). If I were a parent, I'd likely handle it much like I would religion or what my kid wanted to do with his/her life. I'd try to steer these things as best I could until they were old/mature enough to (somewhat) understand the gravity of these things and think about them a bit more independently.

    52. Re:Let's fix them all! by Relayman · · Score: 1

      I'm not excited about your use of "malfunctioning". It's not the same as being born with a missing leg. It's more like being born with a 36" vertical leap. I feel the pluses outweigh the minuses.

      --
      If I used a sig over again, would anyone notice?
    53. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      I wish I had mod points because you deserve some.

    54. Re:Let's fix them all! by RobertLTux · · Score: 1

      Sorry i did get a bit mixed up the "red bull" trick is more for ADD but the point still holds i would bet that "non medical" methods can also work. In the case of autism it helps if you provide a stable environment with a defined order (hint i have a brother that is an autisic savant).

      --
      Any person using FTFY or editing my postings agrees to a US$50.00 charge
    55. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      I have had to memorize social behaviors to be successful in work.

      This is the single most difficult thing I do on a day-to-day basis. Just trying to figure out what type of responses I need to give people takes up most of my thoughts, and on top of that, getting my body language to seem normal is tough as well.

      I agree wholeheartedly with what you say though, about not needing to be fixed, I would rather be this way than be "Normal". At the very least, it makes my life more interesting.

    56. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      Face blindness: I hate it. I have to use hair. Hair is how I recognize people, what sucks is when they drastically change their haircut. Eventually I recognize a person by their face, but it takes seeing them several times before I can remember it. It also helps if they have something unique about them, like body shape, or height, or (obviously) a unique hair style.

      Except for this one friend of mine, I knew her for several years, but she kept switching her hair from being curly to being straight, to up in a bun, changing color, changing length... It always threw me off, I would have to be standing directly in front of her for about second before I could recognize her based off of other features. (She was pretty short, had rosy cheeks, and had a very unique voice and method of speaking)

    57. Re:Let's fix them all! by Anonymous Coward · · Score: 0

      :( This post made me come to a sad realization.

    58. Re:Let's fix them all! by Slashdot+Parent · · Score: 1

      If you can suddenly understand the opposite sex and get them to sleep with you quickly, but no longer do basic math in your head, is that a good trade?

      Depends on the person, I guess. Personally, I'd rather be fucking than adding, but to each his own.

      --
      They don't grade fathers, but if your daughter's a stripper, you fucked up. --Chris Rock
    59. Re:Let's fix them all! by Slashdot+Parent · · Score: 1

      so, you'd rather do basic math in your head than sleep with hotties?
      what are you, gay?

      I'm not gay, so take this with a grain of salt, but I'm pretty sure that gay people still like to sleep with hotties. Just hotties of their same sex.

      --
      They don't grade fathers, but if your daughter's a stripper, you fucked up. --Chris Rock
    60. Re:Let's fix them all! by JoeMerchant · · Score: 1

      It's all good fun until your latest conquest swindles you out of your life savings because you don't understand how all that money stuff actually works.

    61. Re:Let's fix them all! by Slashdot+Parent · · Score: 1

      It's all good fun until your latest conquest swindles you out of your life savings because you don't understand how all that money stuff actually works.

      I feel like not understanding how that money stuff works is pretty common among lower-functioning autistic people. Presumably, part of the brain "rewiring" would involve learning to understand money, no?

      Depending on how good of a fuck this conquest is, as compared with the size of my life savings, it could still wind up working out in my favor. And if worse came to worse, I could always use my new found social skills to land myself a wealthy woman!

      --
      They don't grade fathers, but if your daughter's a stripper, you fucked up. --Chris Rock
    62. Re:Let's fix them all! by JoeMerchant · · Score: 1

      Not to rain on the imaginary parade, but back in real life I do know more than a couple of men who have slept their way into food, clothing, shelter, travel, etc. One made it work with a woman for almost 5 years, but the only ones I know that have really pulled it off long term have been gay - which is fine for them, but the road was typically pretty rocky, taking them to a pretty low point before getting plucked out of the gutter by their sugar daddy.

    63. Re:Let's fix them all! by Slashdot+Parent · · Score: 1

      Well, I'm not autistic, so the notion of learning social skills at the expense of basic arithmetic is a hypothetical one.

      If we're talking real life, I wouldn't be able to make the mooching thing work. Maybe it's different for younger folks, but for an old fart like me, it'd feel like someone sawed off my testicles with a sawzall to take on a sugar mommy.

      --
      They don't grade fathers, but if your daughter's a stripper, you fucked up. --Chris Rock
  4. If bad thriller movies have taught us anything... by StefanJ · · Score: 5, Informative

    ...any experiments along these lines will lead to the subjects developing terrifying mental powers, leading to a series of events ending with the callous lead scientist having his head explode.

  5. No surprise here by wbr1 · · Score: 3, Informative

    For decades it was thought that no new nerve cells could grow in the brain. In the last few years we have discovered that the nervous system is more plastic than we thought.
    That said, it is obviously more flexible the younger you are, so if you can spot signs of neurological problems early and devise treatment regimens to offset, balance, or repair those problems it makes sense to do it as early as possible, even if it can be done to some degree later.

    --
    Silence is a state of mime.
    1. Re:No surprise here by JoeMerchant · · Score: 2

      Judging by the article, any human trials of this are 20+ years out.

    2. Re:No surprise here by jcaplan · · Score: 1

      Creation of new nerve cells (neurons) in the adult human brain has only been only confirmed in a couple areas. (Granule cells of the dentate gyrus of the hippocampus, an area involved in forming new memories and cells which migrate to the olfactory bulb.) Much searching in other places including studies looking at uptake of radioactive particles from atmospheric nuclear bomb testing has shown that if new neurons are created in other areas, the rate must be extremely low. The plasticity of the adult nervous system comes from forming new connections between neurons, pruning existing connections, changing the strength of those connections and changing the sensitivity of a neuron to inputs. This forming of new connections and changing of connection strengths between neurons is lifelong and robust and is key to adult learning. Research that showed "critical periods" for certain kinds of brain development, such as binocular vision, led some to assume that this meant that new learning was more limited than it is and this idea sometimes got mixed in with the rarity of new neuron growth as a limit to plasticity. All that said, early intervention can be hugely helpful as the young brain is much more plastic than the adult brain.

      The treatment regimen for the mice was to stop suppressing the gene that they had attached a chemically activated genetic switch to, so this particular treatment would not be applicable to humans who haven't been genetically engineered from birth to have this switch in the first place. If it were possible to insert a copy of this gene into humans with the proper regulation that might be a route for treatment, but the regulation bit is critical and difficult and I believe beyond what we can do with current technology. Perhaps someone who actually knows genetics might be able to comment on this question better than I.

      They do suggest that there could be treatments for this genetic defect. They mention that drugs that block the (metabotropic) glutamate receptor "might hold promise for designing treatment strategies for non-syndromic autism," since the gene in question regulates this glutamate receptor.

      The cool thing about the paper is that is showed that they could "rescue" the mice by turning on the gene switch and they were able to see that the mice recovered typical function at a cellular level and at a behavioral level, suggesting that if it were possible to re-enable this gene in humans that you might see some similar effects.

      PS If you want to read the original paper, post here and I'll send you the pdf.

    3. Re:No surprise here by Anonymous Coward · · Score: 0

      BriManAla gmail

      please.

  6. The Speed of Dark by CityZen · · Score: 1

    Wow. How soon until the story in "The Speed of Dark" ( http://en.wikipedia.org/wiki/Speed_of_Dark ) becomes real life?

  7. other conditions may benefit by Anonymous Coward · · Score: 0

    This might have beneficial repercussions for conditions that range inside the encephalopatic epilepsies continuum. The resulting disabilities are considered in a large part to emanate from interferences in brain development during the aforementionned critical windows.

  8. There is no such thing as autism or "aspbergers". by Anonymous Coward · · Score: 0, Troll

    They are curse words used by idiots to describe what used to be called "nerds" or "geeks" or "Poindexters". These fake diseases need to stop. Seriously. Stop hiding between made-up bullshit diseases. I'm probably going to be called an "ass-pie" or "assburger" now, but... no. I suck at attracting females and a bunch of other social things, but there is no need to label that with a disease. I am fully aware of it and don't try to hide it. I don't need a fictional "condition" to hide behind.

    The worst, however, are people who proudly announce themselves to have these fake "diseases". They are even worse than the dumb people who use them as insults.

  9. Asperger by Anonymous Coward · · Score: 0

    Asperger is a form of high functioning autism. If someone is socially awkward, but good at logic due to this, I wonder if this rewiring would have any effect, and if so if itd remove the social awkwardness but at the cost of the logic skills.

    1. Re:Asperger by Anonymous Coward · · Score: 0

      Maybe, but at what point to you start fixing people who aren't really broke.

    2. Re:Asperger by mrbester · · Score: 1

      Time for a car analogy!

      My car has shitty gas mileage but is fast and powerful. Should I fuck around with the engine so it performs more like the societally accepted "norm" of a Jetta?

      --
      "Wait. Something's happening. It's opening up! My God, it's full of apricots!"
    3. Re:Asperger by Anonymous Coward · · Score: 0

      Why the assumption that your car would be any less powerful? If something in it is genuinely wrong, it'll probably be *more* fast and powerful after you fix it. It's a terrible analogy.

      Meany recent nutritional treatments for autism addressing mitochondrial misfunction and deficiencies of things like folinic acid result in children scoring higher on cognitive function assessments as well as decreasing symptoms of autism. Basically, they fucked around with the engine and the gas mileage got better, but so did the top end and 0-60.

      The assumption that "fixing" autism is all about making them normal is somewhat narrow minded. It's not unbelievable that one day we'll be able to get rid of the deficits without harming any blessings someone on the spectrum might have.

    4. Re:Asperger by Anonymous Coward · · Score: 0

      Yeah, but you have to admit that there's a difference between giving someone suppliments that the body should have, and using drugs or other methods to block symptoms and otherwise screw with things.
      The first method is probably OK, the second will probably cause them to lose some advantages and such.

      Going back to the car analogy, improving the timing and fuel quality/additives to get better emissions is one thing, as it would also improve performance. Doing stuff like recirculating exhaust gas on the other hand... worsens performance instead.

      -RobbieThe1st

    5. Re:Asperger by Anonymous Coward · · Score: 0

      It depends. We really don't know enough about cause & effect when it comes to autism spectrum disorders. One theory says that kids with AS develop better logic as a coping mechanism, or as an alternative to social empathy, and wouldn't have developed those abilities without it. Another theory is that brute-force intelligence is basically what determines where a kid wired for ASD ends up on the spectrum... supra-genius? Aspie. Normal intelligence? Classic textbook autism.

      I tend to think it's more of the former than the latter, but not entirely one or the other. Pithy motivational posters aside, the potential of the human brain is NOT infinite. It's more like a big, soggy FPGA with a chunk of rewritable flash, and a lot of write-once memory.

      In computer terms, here's how I see the difference between neurotypical and aspie brains:

      Neurotypical: 8-core Intel Atom running at 1GHz with 256mb of primary cache, 512mb of ram and a terrabyte hard drive. Effortless multitasking and social interaction, which depends upon nonstop parallel processing to work effectively.

      Aspie: dual-core AMD64 overclocked to 4GHz with a gig of primary cache & petabyte SSD RAID array for long-term storage, but only enough ram to back up a single set of register data, and a bug that causes all cache to get flushed whenever an IRQ fires while another is being serviced. The net result is that the obsession of the moment has blisteringly-fast execution speed, but any interruption that comes along and demands the Aspie's full undivided attention is going to cause a stack overflow and total loss of everything in working memory that wasn't backed up to the hard drive before it happened.

    6. Re:Asperger by mrbester · · Score: 1

      But isn't putting additives in fuel the same as prescribing supplements / drugs to correct a perceived flaw? My engine is fine, does what it was designed to do and does it well. It wasn't designed for urban pootling in low gear, unless I give it drugs to "correct" this "problem" (quoted because it isn't a problem that needs correcting in my opinion; it's my car, not some focus group's)

      --
      "Wait. Something's happening. It's opening up! My God, it's full of apricots!"
  10. trying to fix everything by Anonymous Coward · · Score: 0

    desperate parents trying to fix everything that don't suit how they want things.
    this is completely unethical, it's good we research it but we should never give parents the power to make their world perfectly flawless...
    the perfect world syndrome is also a disease...

  11. Re:No such thing as 'autism' by Anonymous Coward · · Score: 0

    Enjoy the wall of hate and despair you've built around yourself.

  12. Re:No such thing as 'autism' by Anonymous Coward · · Score: 0

    http://www.reuters.com/article/2012/09/12/us-australia-autism-genetic-idUSBRE88B0DH20120912

    I'm surprised they found a genetic test to predict parental abuse in advance.

    http://en.wikipedia.org/wiki/Refrigerator_mother_theory may give more info. Basically, the idea that there's no such thing as autism is absolute bunk. There are plenty of physical comorbid conditions to the mental conditions of autism spectrum disorders.

    Talk to some of the people who actually do the studies, and you might learn something.

  13. MDMA by Anonymous Coward · · Score: 0

    MDMA seems to do this to me if the strong and clean enough(Tested MDMA)
    However its a mix bag as lower quality and speedier chems tend to disrupt my thought process, where my brain will end up fighting the forced socialization.. and changes to thought processes.

  14. Re:No such thing as 'autism' by wonkey_monkey · · Score: 1
    And your medical qualifications are... what, exactly? I'm going to take a wild stab in the dark at "non-existent."

    'Autism' is simply

    Wow, three words in and you've already got it wrong ;)

    --
    systemd is Roko's Basilisk.
  15. Re:No such thing as 'autism' by wonkey_monkey · · Score: 1

    PS Should have said this in the post above, but if anyone mods the GP down, feel free to mod my posts down too so even less people see this.

    --
    systemd is Roko's Basilisk.
  16. Re:No such thing as 'autism' by Anonymous Coward · · Score: 2, Informative

    Seriously, and with all due respect, fuck you very much.

  17. Nope. by Anonymous Coward · · Score: 0

    Douchebag neurotypicals yet again. I'm just fine, thank you. Better than neurotypicals, certainly. Therefore, I propose that neurotypicals are "rewired" or eliminated because their mental skills are lacking.

  18. At first glance... by lewoot · · Score: 0

    I read the title as 'rewiring the artistic brain' and I was like 'awesome, I can explain science to my hipster friends now' and then I was thoroughly disappointed

  19. Re:If bad thriller movies have taught us anything. by Coppit · · Score: 1

    Where do I sign up?

  20. Re:No such thing as 'autism' by Anonymous Coward · · Score: 0

    So you're saying that scientists who've found those genetic correlations are lying?
    That the studies that showed mitochondrial malfunction (a biological disorder) correlates strongly with the presence of autism symptoms, and when treated, patients quickly improve (it's not a cure, but it can help a lot with lower functioning autistics who happen to have that as one of the root causes) are also lying?

    Is this one of those "there's thousands of studies, but I refuse to believe any of them" things?

    Just because abuse can create autism-like symptoms doesn't mean autism doesn't exist. A pebble in the sock can create sprained ankle like symptoms (a limp, favoring one foot, etc) but it doesn't mean sprained ankles don't exist.

  21. Autistic brains aren't made of wires by Culture20 · · Score: 1

    They're made of neurons. There's no wiring involved.

  22. There is no such thing as autism or "aspbergers" by Anonymous Coward · · Score: 1

    They are curse words used by idiots to describe what used to be called "nerds" or "geeks" or "Poindexters". These fake diseases need to stop. Seriously. Stop hiding between made-up bullshit diseases. I'm probably going to be called an "ass-pie" or "assburger" now, but... no. I suck at attracting females and a bunch of other social things, but there is no need to label that with a disease. I am fully aware of it and don't try to hide it. I don't need a fictional "condition" to hide behind.

    The worst, however, are people who proudly announce themselves to have these fake "diseases". They are even worse than the dumb people who use them as insults.

    +5, Insightful

  23. Re:No such thing as 'autism' by Anonymous Coward · · Score: 0

    What a brilliant, scientific rebuttal! Do you plan to get your 'rebuttal' published by a scientific journal?

    See Clara Claiborne Park's own 'confession' below, of how she made her own daughter 'autistic'.

    Let me see... mother beats the crap out of her daughter, and from then on, her daughter doesn't respond to her. Could they possibly be linked? No - it can't be! It must be 'genetic'! All nice and 'sciencey', none of those 'scary' emotions for you Slashdotters, right? What a joke.

    And I'M the one with a "wall of hate and despair" around myself? I can FEEL, unlike the Slashdot sociopaths, you sad, pathetic tossers.

  24. Re:No such thing as 'autism' by Earl_Parvisjam · · Score: 1

    Wow, you sir or madam are a piece of work. Your entire stance is based on prejudicial opinion and a book from 1967. Your concept of the terms "fact" and "truth" is intriguing and your use of a character attack right after mentioning logical fallacies is brilliantly timed; assuming you are trolling.

    At least you have the temerity to post as anonymous. It helps clarify how much we should care about your opinion, while illustrating just how serious you are about a subject you have no idea about. I thought the vaccine blaming crowd was bad...

  25. Re:Why fucking bother? by Anonymous Coward · · Score: 0, Funny

    Wow your poor monitor, smartphone, whatever you posted this on. How do you get the mouth spittle off it in order to see what your typing? You know it is actually better if you breath through your nose at it has the function of being a filter for the air you breath. Thats right teath together, lips closed, and in through the nose out through the nose. Good neandrethal.

  26. Re:If bad thriller movies have taught us anything. by O('_')O_Bush · · Score: 2

    Or... as the previous attempts at rewiring the brain did.... lobotomies.

    --
    while(1) attack(People.Sandy);
  27. Re:I thought... by Anonymous Coward · · Score: 0

    Actually, it may be caused not by a distant father, but an old father in some cases.

  28. Re:If bad thriller movies have taught us anything. by JoeMerchant · · Score: 1

    Oh you pretty things (oh you pretty things)
    Don't you know you're driving your
    Mamas and papas insane
    Oh you pretty things (oh you pretty things)
    Don't you know you're driving your
    Mamas and papas insane
    Let me make it plain
    You gotta make way for the homo superior

    David Bowie 1971

  29. Re:There is no such thing as autism or "aspbergers by WhitePanther5000 · · Score: 0

    You're retarded.

  30. Patched over is not repaired by Anonymous Coward · · Score: 4, Interesting

    Posting as AC, since I don't want my employer to read this.

    I have been diagnosed with aspergers. Anyone I have encountered in over 40 years on this planet that has any form of autism, mild or not, has to use their conscious brain functions to "patch" what "neurotypicals" have woven into their subconscious brain. People that think they are "superior to neurotypicals" in general don't realize what the part is they are missing. They are mistaking a high IQ for superiority while in practice, people with lower IQs as themselves but not with autism, tend to be more successful in life; in procreation, in happiness and in fortune.

    Sure, their higher IQs may make them "better citizens", but their high IQ and the decisions they make because of that, are not directly because of their autism. There are plenty of people with autism that don't have a high IQ, they get diagnosed with other forms like "classical autism" because they lack the brain power to consciously pick up the lack of social adaptation. This is a classical case of correlation is not the same as causation. I'm getting tired of those autistic people thinking they are superior just because they (once again) fail to see the point of social skills. The ones claiming this are usually not independently wealthy happy fathers, but rather single male workforce people that have individualistic jobs with no leadership requirements. Very few are female, but other than the single bit, they tend to be rather unhappy and not incredibly well off.

    Regarding the OT, I am skeptical about actual repair. I do hope it is possible since it takes a lot of energy to get by in normal life, even if you are "well adapted" like I classify. However, I think that if you only look at behavioral results, you may mistake conscious learning and decision making for actual instinctive behavior. Further testing will have to be done before claims should be made.

    1. Re:Patched over is not repaired by Anonymous Coward · · Score: 0

      I'm basically a person like you described. I've given some thought as to the way I plan to live my life versus the "normal people" as you describe and finding niches and spaces where I can thrive. I'm well-spoken and deal with basic emotions very well but can't relate to emotions linked to social functioning for my life - trying to relate to these in another person just makes me feel nothing.

      I'm thinking a big part of this is making sure I don't artificially limit myself by being bitter about it or alienating myself even more from "normal people". Feeling nothing is easier to paint over than feeling anger and paranoia after all, and those emotions waste a lot of energy.

    2. Re:Patched over is not repaired by Anonymous Coward · · Score: 0

      lsd

  31. Re:No such thing as 'autism' by TapeCutter · · Score: 1

    I feel your suffering, now if you would just let those who know what they are talking about rearrange some of your brain wiring, we would all be in a lot less pain.

    --
    And did you exchange a walk on part in the war for a lead role in a cage? - Pink Floyd.
  32. Re:No such thing as 'autism' by Anonymous Coward · · Score: 0

    That's not valid scientific reasoning. That A anecdotally caused B in one case doesn''t prove that B* is generally caused by A. A=parental abuse, B=mutism, B*=autism.

  33. Re:Is that a good trade? by TaoPhoenix · · Score: 1

    "If you gain social intelligence at the cost of creativity, have you been improved? If you can suddenly understand the opposite sex and get them to sleep with you quickly, but no longer do (basic) math in your head, is that a good trade?" Notice the word Basic. Let's change that to "Complex".

    Maybe, and this is in a sense exactly what the Autism *spectrum* is all about. A word from the New Age lit is useful here: Esoteric. Autistic people often tend to like esoteric things. The word has connotations of "obscure but with mystique wrapped in with it". Looking at the item I re-quoted, what "Creativity" are we referring to? Nice, socially understandable Creativity like a nice song? Or living in a room where the spatial layout of everything is symbolically congruent to the XOR of observed behavior in a particular bee hive and a particular ant hill that the person studied and recorded? Isn't that "Creative" too? Sure it is. But doing XOR insect calculations in your head doesn't help you in a conversation with a budding romantic partner.

    So suppose the autistic person can do seven different types of that kind of creativity. None of them help with a date. He might indeed be willing to trade those kinds of calculations for "slowing down" and "magically" seeing better social results.

    --
    My first Journal Entry ever, in 8 years! http://slashdot.org/journal/365947/aphelion-scifi-fantasy-horror-poetry-webzine
  34. Re:There is no such thing as autism or "aspbergers by Anonymous Coward · · Score: 0

    Yes, you sure are.

  35. Autisim is not universally thought to be miswiring by Theovon · · Score: 1

    There is a huge contingent of medical practitioners, particularly nutritionists, who believe that ASD symptoms are the result of the liver being inadequate to filter toxins from the blood. Diet modifications have been documented to alleviate many ASD symptoms.

  36. And then we were six. by tlambert · · Score: 1

    Just saying.

  37. Gut Bacteria by nanospook · · Score: 1

    Here is an interesting article on Gut Bacteria in the Economist.. Autism is mentioned as well.. worth a good read.. http://www.economist.com/node/21560523

    --
    Have you fscked your local propeller head today?
  38. Re:No such thing as 'autism' by Anonymous Coward · · Score: 0

    > Hence the refusal to look their parents in the eye, refusal to accept affection, etc. from their parents,
    > tantrums if anything is changed in their environment.

    We don't look *anyone* in the eye, in no small part because when we DO, people get visibly freaked out and spooked by it. And it feels weird, like trying to line up two strong identical magnets with sides of the same polarity facing each other.

    We're fine with receiving affection. Where things get complicated is when socially-appropriate reciprocity becomes a requirement, and we have to try and figure out when brutal honesty is inappropriate. If somebody cries because they aren't going to see us for a week, we have no idea how to respond -- we're going to spend the next week at work, stressed and sleep-deprived, solving the world's problems and putting out fire after fire. We might think about them for 3 minutes between Monday and Friday. So in that context, crying just seems like histrionic over-reaction. Ditto, for the welcome-upon-arrival. To us, the whole week away just kind of collapses down into a few minutes. We feel as emotional about arriving as we'd have felt if we went to go pick up a pizza, returned 15 minutes later, and had someone instantly launch into "omygodImissedYousoMUCH". It's like, "WTF, I was away for ${short-time}, not stranded on an uninhabited island and presumed dead for 20years".

    If I arrive at a friend or family member's house, find the neighborhood in ruins because a tornado destroyed it 5 minutes earlier, and they come climbing alive from the rubble, yes, I'll probably be tearful with joy to see them alive. Recent tornadic destruction would definitely qualify as a mitigating circumstance worthy of a tearful reunion. If I live 200 miles away and meet up with them for the first time post-disaster at their vacant lot, I'm more likely to notice the Verizon crew laying new fiber, and the conversation will probably start with an excited question about whether they're going to be able to get FIOS once their house is rebuilt.

    We don't throw tantrums when something changes in our environment. We throw tantrums when something changes negatively in our environment, and we're forcibly prevented from doing anything about it (leaving, researching possible solutions, whatever). Usually, this is harmful to the Aspie's objective long-term interest... but occasionally, it results in an aspie hero saving the day in the face of some unfathomable catastrophe while the neurotypicals were cowering in fear, running around like panicked ants, or passively holding hands with a loved one and waiting to die together.

  39. Re:There is no such thing as autism or "aspbergers by Anonymous Coward · · Score: 0

    As someone with an autistic brother, you're a fucking idiot.

  40. On a related note.. by tlambert · · Score: 1

    There is a huge contingent of medical practitioners, particularly nutritionists, who believe that ASD symptoms are the result of the liver being inadequate to filter toxins from the blood. Diet modifications have been documented to alleviate many ASD symptoms.

    How is that colon cleanse going? Solved your heavy metal problems yet?

  41. Re:No such thing as 'autism' by Anonymous Coward · · Score: 0

    Holy fuck, apparently LowRentEntertainment trolling on Slasdot now.

  42. Re:No such thing as 'autism' by Anonymous Coward · · Score: 0

    Hey LowIQEntertainment. What's next, are you going to say cancer is fake?
    http://www.youtube.com/user/LowRentEntertainment

  43. Re:Is that a good trade? by JoeMerchant · · Score: 2

    So suppose the autistic person can do seven different types of that kind of creativity. None of them help with a date. He might indeed be willing to trade those kinds of calculations for "slowing down" and "magically" seeing better social results.

    He might, one definition/distinction I read between autism and Aspergers was that a true autistic wouldn't care, where an aspie would give anything to be "more normal."

    Diversity is strength, suppression of diversity has led to some dark places.

  44. Re:Is that a good trade? by Anonymous Coward · · Score: 0

    > a true autistic wouldn't care, where an aspie would give anything to be "more normal."

    I agree, and disagree. When I was 20, I would have given just about anything to be "more normal"

    Now, in my 30s, I don't really care anymore. I've carved out my niche, figured out what makes me happy, and I'd have to think about any trade-offs involved with becoming "more normal". I wouldn't mind having slightly better organizational skills, and would probably be better off if I didn't get totally caught up in obsessive special interests that randomly change from week to week or month to month, but there are limits to what I'd trade for improvement.

    Some psychiatrists might say I've become schizoid ( http://en.wikipedia.org/wiki/Schizoid ) in my old age. I'd disagree vehemently, and point out that I'm neither anhedonic nor avolitional... then grudgingly concede that I'd probably be both without dextroamphetamine, but remind them that my childhood was so stereotypically "aspie" (backed up by abundant video, photographic, and comments-in-my-yearbooks proof), it almost hurts. Nevertheless, I'd argue that the remainder of traits on the SPD list could be equally argued as traits of a well-adjusted adult aspie who's come to terms with his AS & figured out what really makes him happy, societal & parental expectations be damned.

  45. Re:No such thing as 'autism' by Relayman · · Score: 1

    But you did such a nice job of putting him in his place!

    --
    If I used a sig over again, would anyone notice?
  46. Re:There is no such thing as autism or "aspbergers by Relayman · · Score: 1

    You sound jealous! It's just too bad not everyone can be HFA.

    --
    If I used a sig over again, would anyone notice?
  47. Speaking as an Aspie... by Anonymous Coward · · Score: 0

    I would have to consider this a form of genocide. It's a peculiar form of genocide, perhaps, but it comes down to the nonvoluntary modification of minds to force conformity based on the current categorization of Asperger's as a disability. I would resist this nonsense.

  48. Treatment Walks a Tightrope by Slashdot+Parent · · Score: 1

    Great, now we'll be able to fix all of them! We really need that! /sarcasm

    I for one find this very offensive. It's like telling all autistics they're malfunctioning.

    Parent of ASD-diagnosed kid here.

    You raise a good point. My wife and I recognize that we're walking a bit of a line in treating him. There are definitely those who subscribe to "The Einstein Syndrome", arguing that when you have a son of a computer geek and a banker, he just may be a little reclusive (I use that word, because it goes beyond being introverted), and that's fine. He's not broken. I see their point.

    On the other hand, humans are social animals. Reclusive people are mostly unhappy, and Einstein was ridiculed mercilessly as a child. Maybe that's why he spent so much time reading physics texts and not interacting with his peers? The happiest and most content people seem to be to be the ones who have warm relationships with family and friends. Not the smartest or richest or anything else.

    We decided to treat our son, from about age 1.5, with some pretty intense play therapy (no medication or anything like that). We immersed his entire life in progressively more abstract symbolic thought, under the guidance of his behavioral therapist. The entire process was amazing to watch. It really did seem to be building a part of this brain that he wasn't using before.

    Some observations:

    1. He absolutely loved the play therapy. Loved it. Loved the therapist. Loved his growing ability to create a new world inside his mind.
    2. He first started learning about past & future, as opposed to everything being in the present, by looking forward to seeing his therapist.
    3. After each session, either in-office or at-home, he was completely exhausted. The workout that we were giving his brain was clearly very intense for him.
    4. Early detection and treatment is definitely the way to go, if at all possible. Much easier to build brain function than to try to modify it later on. Also, sidesteps the "you're broken" factor because you're just stimulating brain development, and who can find fault in that?
    5. He is now an extrovert, which I find to be completely hilarious because I love irony. The kid who always sat in a corner alone, banging his head on the floor over and over and over again all day long now lights up a room when he enters.
    6. At this point, you would never guess what he was like as a toddler. The head-banging. The routines. The rigidity. The literal/mechanical nature (a toy truck was not a toy for him, it was a hunk of plastic with wheels to spin.. and spin... and spin... and spin... and spin.. and god help you if you tried to interrupt the spinning...).

    Looking back, I believe that we did the right thing for him. Like I said, humans are social creatures. It was important to us to try to make him more balanced.

    --
    They don't grade fathers, but if your daughter's a stripper, you fucked up. --Chris Rock
  49. Ther is no cure by Anonymous Coward · · Score: 0

    Being a person with autism I know that no matter what I do there will be no cure, I can change my behaviour but a spinning thing will always capture me in its thrawl. I will never be able to recognise a face like normal people do, I will never understand what people are thingking even though I have a very good map of how they get from one thought to another and how they are willing to change their moral code to to fit their current wants. To constantly confuse their wants with their needs. No matter how normalised I become I will never be accepted because I am an alien amoung my own species. I like who I am. Some people fear me purely because I am different and therefore cannot predict my thoughs therefore I am a threat to their limmited understanding of my existance. No matter how hard I work I will always be on the outside and I don't care.