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Rewiring the Autistic Brain

sciencehabit writes "Signs of autism — such as impaired social skills and repetitive, ritualistic movements — usually begin to appear when a child is about 18 months old. Autism is thought to result from miswired connections in the developing brain, and many experts believe that therapies must begin during a 'critical window,' before the faulty circuits become fixed in place. But a new study (abstract) shows that at least one malfunctioning circuit can be repaired after that window closes, holding out hope that in some forms of autism, abnormal circuits in the brain can be corrected even after their development is complete."

9 of 139 comments (clear)

  1. Let's fix them all! by BenoitRen · · Score: 4, Insightful

    Great, now we'll be able to fix all of them! We really need that! /sarcasm

    I for one find this very offensive. It's like telling all autistics they're malfunctioning.

    1. Re:Let's fix them all! by Anonymous Coward · · Score: 3, Insightful

      Preface: I'm diagnosed with asperger's, a form of high-functioning autism, and I do a lot of work relating to autism advocacy.

      That being said, the language might need a little work, but we don't try to pretend a person with a deformed arm doesn't have a deformed arm. People on the autism spectrum tend to have a variety of physical issues relating to gut bacteria, mitochondrial function, nutritional levels and other things. Many of these issues can also be seen in their mothers, and there's some strong correlation between certain nutritional levels in the mother and the incidence of autism. There's really no question that autism has a physical element. It's somewhat disingenuous to try to talk as if autism isn't a "malfunction" in the human body.

      If someone is missing a leg, and goes on to lead a normal life anyway, you don't pretend like it never happened, you stand proud of them for overcoming it. If you want to support those on the spectrum, be proud of those who accept that there's something malfunctioning in their body and find a way to make life work despite that. Don't try to pretend like there's nothing malfunctioning, because the first message that sends is "if you can't do it, it's all your fault" and you'd never tell that to a person who couldn't walk because they had a deformed leg.

    2. Re:Let's fix them all! by TemperedAlchemist · · Score: 5, Insightful

      We are, in a way. But you know what's to be said about judging a fish on its ability to climb a tree. Only we're like monkeys that have difficulty learning how to climb trees, and perhaps more importantly, don't like climbing trees even if we do learn.

      Should we learn how to climb trees? Definitely, you don't know when you might need to climb a tree as a monkey. But perhaps not all monkeys have to climb trees to be monkeys. Maybe they're perfectly happy on the ground using sticks to eat bugs. Not liking climbing trees (and being absolutely terrible at it) shouldn't mean there's something wrong that needs to be corrected.

      And think of all the things the ground monkey can explore. On the ground there are rivers to play in and lots more space than up in the trees. And maybe that's what the monkey community needs, monkeys that can find nice fresh sources of water on the ground or somewhere to bathe as well as monkeys that enjoy living their whole lives in trees eating fruit and swinging around.

    3. Re:Let's fix them all! by Anonymous Coward · · Score: 3, Insightful

      The tone is offensive yes, but I can entirely understand the motivation to help those with low-function autism live more normal lives. However, being HFA myself, I'm not certain I'd want to be "fixed" at this point. I wouldn't be myself, and I've grown to accept who I am.

      However, growing up without some of the social and emotional problems I have faced would have been much more pleasant, and it makes perfect sense why a parent might want to help keep a child from going through it. And for LFA things can be much, much worse.

    4. Re:Let's fix them all! by JoeMerchant · · Score: 4, Insightful

      Define improved.

      If you gain social intelligence at the cost of creativity, have you been improved?

      If you can suddenly understand the opposite sex and get them to sleep with you quickly, but no longer do basic math in your head, is that a good trade?

      Problem with brain re-wiring is that you won't often "unlock a secret room full of new abilities", more often you'll open a new processing section that needs training and demands resources from other functions.

    5. Re:Let's fix them all! by artor3 · · Score: 3, Insightful

      Correlation is not causation. A fraction of autistic people (10%) are naturally gifted at math or creativity, but that doesn't mean that autism causes that talent. It is quite possible that the genetic causes for autism ALSO cause savant syndrome, and that we could cure the former without touching the latter. Even if not, we could cure the 90+% that don't get any benefit from their autism, and leave the savants untouched

  2. If bad thriller movies have taught us anything... by StefanJ · · Score: 5, Informative

    ...any experiments along these lines will lead to the subjects developing terrifying mental powers, leading to a series of events ending with the callous lead scientist having his head explode.

  3. No surprise here by wbr1 · · Score: 3, Informative

    For decades it was thought that no new nerve cells could grow in the brain. In the last few years we have discovered that the nervous system is more plastic than we thought.
    That said, it is obviously more flexible the younger you are, so if you can spot signs of neurological problems early and devise treatment regimens to offset, balance, or repair those problems it makes sense to do it as early as possible, even if it can be done to some degree later.

    --
    Silence is a state of mime.
  4. Patched over is not repaired by Anonymous Coward · · Score: 4, Interesting

    Posting as AC, since I don't want my employer to read this.

    I have been diagnosed with aspergers. Anyone I have encountered in over 40 years on this planet that has any form of autism, mild or not, has to use their conscious brain functions to "patch" what "neurotypicals" have woven into their subconscious brain. People that think they are "superior to neurotypicals" in general don't realize what the part is they are missing. They are mistaking a high IQ for superiority while in practice, people with lower IQs as themselves but not with autism, tend to be more successful in life; in procreation, in happiness and in fortune.

    Sure, their higher IQs may make them "better citizens", but their high IQ and the decisions they make because of that, are not directly because of their autism. There are plenty of people with autism that don't have a high IQ, they get diagnosed with other forms like "classical autism" because they lack the brain power to consciously pick up the lack of social adaptation. This is a classical case of correlation is not the same as causation. I'm getting tired of those autistic people thinking they are superior just because they (once again) fail to see the point of social skills. The ones claiming this are usually not independently wealthy happy fathers, but rather single male workforce people that have individualistic jobs with no leadership requirements. Very few are female, but other than the single bit, they tend to be rather unhappy and not incredibly well off.

    Regarding the OT, I am skeptical about actual repair. I do hope it is possible since it takes a lot of energy to get by in normal life, even if you are "well adapted" like I classify. However, I think that if you only look at behavioral results, you may mistake conscious learning and decision making for actual instinctive behavior. Further testing will have to be done before claims should be made.