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Rewiring the Autistic Brain

sciencehabit writes "Signs of autism — such as impaired social skills and repetitive, ritualistic movements — usually begin to appear when a child is about 18 months old. Autism is thought to result from miswired connections in the developing brain, and many experts believe that therapies must begin during a 'critical window,' before the faulty circuits become fixed in place. But a new study (abstract) shows that at least one malfunctioning circuit can be repaired after that window closes, holding out hope that in some forms of autism, abnormal circuits in the brain can be corrected even after their development is complete."

72 of 139 comments (clear)

  1. But, but... by Anonymous Coward · · Score: 2, Funny

    Who will write our file systems??

  2. Anyone else insulted by this? by Anonymous Coward · · Score: 1, Informative

    Most symptoms of an ASD can be patched over with a little studying & practice & I know this from experience.

  3. Let's fix them all! by BenoitRen · · Score: 4, Insightful

    Great, now we'll be able to fix all of them! We really need that! /sarcasm

    I for one find this very offensive. It's like telling all autistics they're malfunctioning.

    1. Re:Let's fix them all! by Anonymous Coward · · Score: 2, Insightful

      I'm unhappy with my intellectual abilities and I have a PhD and no mental issues. If someone could fix me to make me smarter, that sounds great. So I'm not sure what you are getting at. Why wouldn't many autistics like to have improved mental functioning, when many normal people do too? In any case yes, autistics are malfunctioning. You may find that offensive in the same way that I find it offensive that my body is set to malfunction within 100 years. Unfortunately facts don't become false just because they are offensive.

    2. Re:Let's fix them all! by Anonymous Coward · · Score: 3, Insightful

      Preface: I'm diagnosed with asperger's, a form of high-functioning autism, and I do a lot of work relating to autism advocacy.

      That being said, the language might need a little work, but we don't try to pretend a person with a deformed arm doesn't have a deformed arm. People on the autism spectrum tend to have a variety of physical issues relating to gut bacteria, mitochondrial function, nutritional levels and other things. Many of these issues can also be seen in their mothers, and there's some strong correlation between certain nutritional levels in the mother and the incidence of autism. There's really no question that autism has a physical element. It's somewhat disingenuous to try to talk as if autism isn't a "malfunction" in the human body.

      If someone is missing a leg, and goes on to lead a normal life anyway, you don't pretend like it never happened, you stand proud of them for overcoming it. If you want to support those on the spectrum, be proud of those who accept that there's something malfunctioning in their body and find a way to make life work despite that. Don't try to pretend like there's nothing malfunctioning, because the first message that sends is "if you can't do it, it's all your fault" and you'd never tell that to a person who couldn't walk because they had a deformed leg.

    3. Re:Let's fix them all! by Earl_Parvisjam · · Score: 1, Insightful

      WTF are you talking about? Do you have any idea what autism is or are you just making crap up? Here's a hint, Autism isn't ADD. Cripes, it's bad enough some people think it's caused by vaccinations without this sort of uninformed blather.

    4. Re:Let's fix them all! by TemperedAlchemist · · Score: 5, Insightful

      We are, in a way. But you know what's to be said about judging a fish on its ability to climb a tree. Only we're like monkeys that have difficulty learning how to climb trees, and perhaps more importantly, don't like climbing trees even if we do learn.

      Should we learn how to climb trees? Definitely, you don't know when you might need to climb a tree as a monkey. But perhaps not all monkeys have to climb trees to be monkeys. Maybe they're perfectly happy on the ground using sticks to eat bugs. Not liking climbing trees (and being absolutely terrible at it) shouldn't mean there's something wrong that needs to be corrected.

      And think of all the things the ground monkey can explore. On the ground there are rivers to play in and lots more space than up in the trees. And maybe that's what the monkey community needs, monkeys that can find nice fresh sources of water on the ground or somewhere to bathe as well as monkeys that enjoy living their whole lives in trees eating fruit and swinging around.

    5. Re:Let's fix them all! by Anonymous Coward · · Score: 3, Insightful

      The tone is offensive yes, but I can entirely understand the motivation to help those with low-function autism live more normal lives. However, being HFA myself, I'm not certain I'd want to be "fixed" at this point. I wouldn't be myself, and I've grown to accept who I am.

      However, growing up without some of the social and emotional problems I have faced would have been much more pleasant, and it makes perfect sense why a parent might want to help keep a child from going through it. And for LFA things can be much, much worse.

    6. Re:Let's fix them all! by Anonymous Coward · · Score: 1

      Don't try to pretend like there's nothing malfunctioning, because the first message that sends is "if you can't do it, it's all your fault" and you'd never tell that to a person who couldn't walk because they had a deformed leg.

      Wouldn't I?

      This is the internet; you have no idea how big an asshole I am IRL.

      I've a pretty good idea.

    7. Re:Let's fix them all! by Anonymous Coward · · Score: 1

      " In any case yes, autistics are malfunctioning."

      You mean like the warmongering, wage caste loving, profiteering, superstitious, corrupt, law abusing "normal people"? We could make an excellent case that normality is just popular malfunctioning.

    8. Re:Let's fix them all! by postbigbang · · Score: 1

      The fight between "neurotypicals" and those within the ASD spectrum will be ongoing. Don't absolve ASD members of the problem with most of the problems you mention, caused by another disorder: sociopathy, and narcissism.

      --
      ---- Teach Peace. It's Cheaper Than War.
    9. Re:Let's fix them all! by TemperedAlchemist · · Score: 1

      Well I can't speak for others, but caffeine does help "treat" my condition. I grow more comfortable socially and it's easier.

      But that's not necessarily fixing anything, just removing a bit social anxiety doesn't mean I small talk with the best of them. I still don't understand people or social nuance with caffeine, it just makes me more willing to passionately rabble on about something that fascinates me. Ask me about the weather and I'll probably start talking about cloud seeding or cosmic rays contributing to more cloud cover.

      I'll probably make a great professor someday.

    10. Re:Let's fix them all! by Anonymous Coward · · Score: 1

      My autistic son is aggressive, self injurious, and nonverbal. Nice that _you_ are offended by the possibility his life could be improved.

    11. Re:Let's fix them all! by JoeMerchant · · Score: 4, Insightful

      Define improved.

      If you gain social intelligence at the cost of creativity, have you been improved?

      If you can suddenly understand the opposite sex and get them to sleep with you quickly, but no longer do basic math in your head, is that a good trade?

      Problem with brain re-wiring is that you won't often "unlock a secret room full of new abilities", more often you'll open a new processing section that needs training and demands resources from other functions.

    12. Re:Let's fix them all! by JoeMerchant · · Score: 1

      With 1/50 male children being diagnosed "on the Autisim spectrum," the category catches a wide variety of people these days, with a lot of variation in social and abstract intellectual functioning.

    13. Re:Let's fix them all! by JoeMerchant · · Score: 1

      Alcohol also removes the social inhibition - regardless of neurotype.

    14. Re:Let's fix them all! by CODiNE · · Score: 1

      I've spent years slowly learning how to eat brussel sprouts, mushrooms, mayo, mustard, cooked carrots, shrimp, calimari... those aren't really big deals but damn if I'll ever like eggs! Working on that for the last 3 years and I just hate em. It's the texture... like chewing on snot or something. At least I can tolerate them once in a while and won't starve if I'm stuck somewhere with scrambled eggs for breakfast.

      --
      Cwm, fjord-bank glyphs vext quiz
    15. Re:Let's fix them all! by macraig · · Score: 1

      I wish I had mod points handy right now. +1 Insightful

    16. Re:Let's fix them all! by Tablizer · · Score: 1

      and it frees up their hands so that monkeys can clobber other monkeys with sticks and stones

    17. Re:Let's fix them all! by sjames · · Score: 2

      Would you be as anxious for the treatment if it was likely to alter your personality and might leave you unable to understand your own doctoral thesis?

      The higher functioning autists might indeed opt-out of such a treatment. It's hard to say what the more withdrawn autists would think of it.

    18. Re:Let's fix them all! by macraig · · Score: 1

      You know what you're describing, don't you? It's the beginning of a speciation event, one based not on physical incompatibilities but behavioral and cognitive ones. It's happened to primates before.

      I'd have settled for a +1 Insightful, but my modpoints wallet is empty.

    19. Re:Let's fix them all! by sjames · · Score: 1

      If someone is missing a leg, and goes on to lead a normal life anyway, you don't pretend like it never happened, you stand proud of them for overcoming it. If you want to support those on the spectrum, be proud of those who accept that there's something malfunctioning in their body and find a way to make life work despite that. Don't try to pretend like there's nothing malfunctioning, because the first message that sends is "if you can't do it, it's all your fault" and you'd never tell that to a person who couldn't walk because they had a deformed leg.

      By the same token, you wouldn't insist that they give up their prosthetic in favor of a more normal looking but potentially less useful transplanted leg. You might offer that choice.

    20. Re:Let's fix them all! by sjames · · Score: 1

      A lot of kids are like that at 4, autistic or not.

    21. Re:Let's fix them all! by memnock · · Score: 1

      I just found out about an alternative hypothesis to the cause of autism: inflammation in the pregnant mother. Apparently an immune disorder in a mother will affect the unborn child.

      https://www.nytimes.com/2012/08/26/opinion/sunday/immune-disorders-and-autism.html?_r=2&pagewanted=all

      I didn't read any further on the topic, but the article does reference at least one researcher, so one could see what kind of study has been performed to support this idea.

    22. Re:Let's fix them all! by Anonymous Coward · · Score: 1

      I was pretty hardcore as a child about eating only specific things, but my mom made it a hundred times worse than it had to be by trying to force me to eat things (and worse, eat large quantities of things that were forced upon me). My willingness to try other foods didn't really thaw until I was in college & could try food in the cafeteria with zero risk of having to eat something I didn't like. There are still certain foods that the mere sight of is enough to put me at risk of throwing up, in no small part thanks to my mom force-feeding them to me as a child.

      Neurotypicals rarely understand, but to an Aspie child, force-feeding is basically rape. Maybe worse. At least rapists don't feel entitled to beat you afterwards for crying or throwing up after they force disgusting objects into your body.

    23. Re:Let's fix them all! by ultranova · · Score: 1

      By the same token, you wouldn't insist that they give up their prosthetic in favor of a more normal looking but potentially less useful transplanted leg.

      Are you referring to the monkey brain prosthetics two stories up from this one, or is this yet another example of Just World Fallacy (you couldn't possibly just be shafted, so every problem you got saddled with must have some kind of at-least-equal payback)?

      You might offer that choice.

      This, actually, rises a question: as our knowledge of brain increases, at what point do we stop needing consent from misworking circuits to apply repairs? Probably not at autistics, but should we listen to the protests of a sociopath who insists that he doesn't want to feel empathy (but will almost certainly go on to harm lots of people if not cured)? How about a crazy religious fanatic? Or even anyone with any kind of religious beliefs at all - they're enemies of reason, after all? Or shall we go another route and cure atheists of their childish need to rebel against clear and obvious gospel truth, whatever that might be? A republican (or anyone you disagree with politically)? A drug addict? A delusional paranoid? An anti-vaccination activist?

      This whole thing is opening a huge can of worms, and since people still sometimes publicly defend eugenics (of the forced sterilization of people they consider inferior variety) even on Slashdot, I'm not at all certain humanity can handle it in a way that won't turn into a horror movie very fast.

      --

      Forget magic. Any technology distinguishable from divine power is insufficiently advanced.

    24. Re:Let's fix them all! by artor3 · · Score: 3, Insightful

      Correlation is not causation. A fraction of autistic people (10%) are naturally gifted at math or creativity, but that doesn't mean that autism causes that talent. It is quite possible that the genetic causes for autism ALSO cause savant syndrome, and that we could cure the former without touching the latter. Even if not, we could cure the 90+% that don't get any benefit from their autism, and leave the savants untouched

    25. Re:Let's fix them all! by sjames · · Score: 1

      What part of LEG sounds like monkey brain prosthetic? :-)

      But no, it's not a just world fallacy, it's just a matter that disruptive changes to a person in adulthood can be devastating even if it seems 'obvious' that it should be a good thing. People blind from early childhood or birth who have their vision 'fixed' as adults rarely get much use from their new vision but have been known to commit suicide. I can't imagine that having such a thing forced upon them would be a good idea.

      Likewise it may seem to us like a transplanted leg would be superior to a prosthetic. It may BE superior for someone who has just lost their leg. In practice, it might be a liability for someone who is already well adapted to their prosthetic. It's not as if they'll hop off the surgical table and go for a jog.They may even go from Olympic contender to barely managing to limp with a cane.

      As for the rest, that is a big part of why I say it may be offered but not insisted upon. It is a huge can of worms. Lets just say I have zero confidence in our legislators or judges to make the right call there if we allow for ANY compulsory treatments.

      In the case of the sociopath, they don't have to be cured if they don't want to be, but at the same time society is not obligated to allow a sociopath to harm others.

    26. Re:Let's fix them all! by Immerman · · Score: 1

      That of course presumes that savants could be detected during the critical window (however large it may be), and that parents would rather have a savant than a child that they can readily relate to.

      --
      --- Most topics have many sides worth arguing, allow me to take one opposite you.
    27. Re:Let's fix them all! by HideyoshiJP · · Score: 1

      I would say that would be entirely up to the person in question to define "improved."

    28. Re:Let's fix them all! by electrosoccertux · · Score: 1

      so, you'd rather do basic math in your head than sleep with hotties?
      what are you, gay?

    29. Re:Let's fix them all! by BenoitRen · · Score: 1

      The problem I have with this reasoning is that, apart from not being able to relate to others well, autism is mainly a problem because of societal norms. As such I don't think they're malfunctioning, but different from most people.

    30. Re:Let's fix them all! by ultranova · · Score: 1

      What part of LEG sounds like monkey brain prosthetic? :-)

      The part where you bring up a prostethic leg in the context of repairing an alleged brain malfunction when there's another story about correcting brain malfunction (induced by cocaine) on monkeys with a brain prosthethic near this.

      Likewise it may seem to us like a transplanted leg would be superior to a prosthetic. It may BE superior for someone who has just lost their leg. In practice, it might be a liability for someone who is already well adapted to their prosthetic. It's not as if they'll hop off the surgical table and go for a jog.They may even go from Olympic contender to barely managing to limp with a cane.

      Ah yes, I see. You were talking about the usefulness to a particular person who knows how to use a prosthethic but not a "real" leg, while I was thinking about the usefulness of prosthethics vs. meat & bone legs in general. My apologies.

      As for the rest, that is a big part of why I say it may be offered but not insisted upon. It is a huge can of worms. Lets just say I have zero confidence in our legislators or judges to make the right call there if we allow for ANY compulsory treatments.

      So... sucks for anyone who happens to get paranoid delusions?

      It's not that I disagree with you, it's just that I don't think not allowing any compulsory treatments will really do much more than screw people over another way. I'm not sure there is a good solution to this problem. Nobody can be trusted with this power, yet the potential benefits of understanding how brains work are too great to leave well enough alone.

      Also, if you really understand how someone's brain works, you'd presumably be able to figure out inputs that alter their internal state so that they'll to accept the treatment, no matter what their reaction to a simple question might normally be. Does that count as coercion? Because while you're free from forceful coercion, the end result is nonetheless that you can not refuse the offer.

      In the case of the sociopath, they don't have to be cured if they don't want to be, but at the same time society is not obligated to allow a sociopath to harm others.

      I really don't see how the society can prevent them, unless we start punishing (imprisonment, socipath registry, do-not-fly list...) people simply for being sociopaths (or perverts, or communists, or atheists, or whatever), and if we do, well... that can of worms is now the Dune edition.

      --

      Forget magic. Any technology distinguishable from divine power is insufficiently advanced.

    31. Re:Let's fix them all! by sjames · · Score: 1

      Actually the AC I replied to is the one who brought up leg, I just replied to the example as given.

      I do understand that mental illness presents a special challenge. The condition itself may cause the person to make bad decisions about treatment. Of course, even calling it a bad decision is a bit of hubris since I have never had the condition nor do I have personal subjective knowledge of what it feels like to be treated. Some claim it's quite the horror and consider it worse than the disease (even when they're in remission). Others see it as a godsend. Meanwhile many mental health professionals consider sitting quietly to be a successful outcome (even when the average person would describe the patient as zombie like).

      Meanwhile, in the old Soviet Union where psychiatry was far more advanced than in the West, they discovered 'sluggish schizophrenia' and treated it aggressively for the good of the patient. It primarily strikes the well educated and presents with questioning socialist doctrine. The best treatment is high dose neuroleptics and confinement in Siberia.

      At least until we develop more wisdom and treatments that are preferred to the disease by most of the patients, I'd say we had best stick with "First do no harm".

      As for the sociopath, if they have actually committed a crime we have considerable latitude in how to treat them. We cannot ethically coerce a psychiatric treatment, but non-punitive custody can be mandated (much like quarantine but hopefully under better conditions). The condition also has bearing on aptitude. A business that puts an untreated sociopath in charge of others creates a huge liability for itself once awareness of the prevalence and nuances of sociopathy becomes more common.

    32. Re:Let's fix them all! by sjames · · Score: 1

      Really, like the condition itself, there seems to be a spectrum. At one end there are people who are only diagnosed in adulthood if ever. On the other are people who don't appear connected enough to the world to survive at all without considerable assistance. In the middle are those who clearly don't connect very well socially but would obviously get along just fine if society could be a bit less militant about it's 'norms'.

      As to where the 'malfunction' line lies, that is a hard question as is usual for this sort of thing.

    33. Re:Let's fix them all! by JoeMerchant · · Score: 2

      Nice thought, but hard (and unfair) to put such decisions on young kids. My parents included me in the decision to skip 2nd grade, in retrospect it was probably the biggest and most painful mistake of my life, but it sounded great at the time. I had just turned seven.

      Many of these more radical interventions are being proposed for kids that are 2.

    34. Re:Let's fix them all! by HideyoshiJP · · Score: 1

      Very true. I think that comes with any big decision like that though. I was thinking more of a relative that was "diagnosed" with high functioning autism when he was in his teens (scare quotes because I believe HFA isn't an actual diagnosis). If I were a parent, I'd likely handle it much like I would religion or what my kid wanted to do with his/her life. I'd try to steer these things as best I could until they were old/mature enough to (somewhat) understand the gravity of these things and think about them a bit more independently.

    35. Re:Let's fix them all! by Relayman · · Score: 1

      I'm not excited about your use of "malfunctioning". It's not the same as being born with a missing leg. It's more like being born with a 36" vertical leap. I feel the pluses outweigh the minuses.

      --
      If I used a sig over again, would anyone notice?
    36. Re:Let's fix them all! by RobertLTux · · Score: 1

      Sorry i did get a bit mixed up the "red bull" trick is more for ADD but the point still holds i would bet that "non medical" methods can also work. In the case of autism it helps if you provide a stable environment with a defined order (hint i have a brother that is an autisic savant).

      --
      Any person using FTFY or editing my postings agrees to a US$50.00 charge
    37. Re:Let's fix them all! by Slashdot+Parent · · Score: 1

      If you can suddenly understand the opposite sex and get them to sleep with you quickly, but no longer do basic math in your head, is that a good trade?

      Depends on the person, I guess. Personally, I'd rather be fucking than adding, but to each his own.

      --
      They don't grade fathers, but if your daughter's a stripper, you fucked up. --Chris Rock
    38. Re:Let's fix them all! by Slashdot+Parent · · Score: 1

      so, you'd rather do basic math in your head than sleep with hotties?
      what are you, gay?

      I'm not gay, so take this with a grain of salt, but I'm pretty sure that gay people still like to sleep with hotties. Just hotties of their same sex.

      --
      They don't grade fathers, but if your daughter's a stripper, you fucked up. --Chris Rock
    39. Re:Let's fix them all! by JoeMerchant · · Score: 1

      It's all good fun until your latest conquest swindles you out of your life savings because you don't understand how all that money stuff actually works.

    40. Re:Let's fix them all! by Slashdot+Parent · · Score: 1

      It's all good fun until your latest conquest swindles you out of your life savings because you don't understand how all that money stuff actually works.

      I feel like not understanding how that money stuff works is pretty common among lower-functioning autistic people. Presumably, part of the brain "rewiring" would involve learning to understand money, no?

      Depending on how good of a fuck this conquest is, as compared with the size of my life savings, it could still wind up working out in my favor. And if worse came to worse, I could always use my new found social skills to land myself a wealthy woman!

      --
      They don't grade fathers, but if your daughter's a stripper, you fucked up. --Chris Rock
    41. Re:Let's fix them all! by JoeMerchant · · Score: 1

      Not to rain on the imaginary parade, but back in real life I do know more than a couple of men who have slept their way into food, clothing, shelter, travel, etc. One made it work with a woman for almost 5 years, but the only ones I know that have really pulled it off long term have been gay - which is fine for them, but the road was typically pretty rocky, taking them to a pretty low point before getting plucked out of the gutter by their sugar daddy.

    42. Re:Let's fix them all! by Slashdot+Parent · · Score: 1

      Well, I'm not autistic, so the notion of learning social skills at the expense of basic arithmetic is a hypothetical one.

      If we're talking real life, I wouldn't be able to make the mooching thing work. Maybe it's different for younger folks, but for an old fart like me, it'd feel like someone sawed off my testicles with a sawzall to take on a sugar mommy.

      --
      They don't grade fathers, but if your daughter's a stripper, you fucked up. --Chris Rock
  4. If bad thriller movies have taught us anything... by StefanJ · · Score: 5, Informative

    ...any experiments along these lines will lead to the subjects developing terrifying mental powers, leading to a series of events ending with the callous lead scientist having his head explode.

  5. No surprise here by wbr1 · · Score: 3, Informative

    For decades it was thought that no new nerve cells could grow in the brain. In the last few years we have discovered that the nervous system is more plastic than we thought.
    That said, it is obviously more flexible the younger you are, so if you can spot signs of neurological problems early and devise treatment regimens to offset, balance, or repair those problems it makes sense to do it as early as possible, even if it can be done to some degree later.

    --
    Silence is a state of mime.
    1. Re:No surprise here by JoeMerchant · · Score: 2

      Judging by the article, any human trials of this are 20+ years out.

    2. Re:No surprise here by jcaplan · · Score: 1

      Creation of new nerve cells (neurons) in the adult human brain has only been only confirmed in a couple areas. (Granule cells of the dentate gyrus of the hippocampus, an area involved in forming new memories and cells which migrate to the olfactory bulb.) Much searching in other places including studies looking at uptake of radioactive particles from atmospheric nuclear bomb testing has shown that if new neurons are created in other areas, the rate must be extremely low. The plasticity of the adult nervous system comes from forming new connections between neurons, pruning existing connections, changing the strength of those connections and changing the sensitivity of a neuron to inputs. This forming of new connections and changing of connection strengths between neurons is lifelong and robust and is key to adult learning. Research that showed "critical periods" for certain kinds of brain development, such as binocular vision, led some to assume that this meant that new learning was more limited than it is and this idea sometimes got mixed in with the rarity of new neuron growth as a limit to plasticity. All that said, early intervention can be hugely helpful as the young brain is much more plastic than the adult brain.

      The treatment regimen for the mice was to stop suppressing the gene that they had attached a chemically activated genetic switch to, so this particular treatment would not be applicable to humans who haven't been genetically engineered from birth to have this switch in the first place. If it were possible to insert a copy of this gene into humans with the proper regulation that might be a route for treatment, but the regulation bit is critical and difficult and I believe beyond what we can do with current technology. Perhaps someone who actually knows genetics might be able to comment on this question better than I.

      They do suggest that there could be treatments for this genetic defect. They mention that drugs that block the (metabotropic) glutamate receptor "might hold promise for designing treatment strategies for non-syndromic autism," since the gene in question regulates this glutamate receptor.

      The cool thing about the paper is that is showed that they could "rescue" the mice by turning on the gene switch and they were able to see that the mice recovered typical function at a cellular level and at a behavioral level, suggesting that if it were possible to re-enable this gene in humans that you might see some similar effects.

      PS If you want to read the original paper, post here and I'll send you the pdf.

  6. The Speed of Dark by CityZen · · Score: 1

    Wow. How soon until the story in "The Speed of Dark" ( http://en.wikipedia.org/wiki/Speed_of_Dark ) becomes real life?

  7. Re:Asperger by mrbester · · Score: 1

    Time for a car analogy!

    My car has shitty gas mileage but is fast and powerful. Should I fuck around with the engine so it performs more like the societally accepted "norm" of a Jetta?

    --
    "Wait. Something's happening. It's opening up! My God, it's full of apricots!"
  8. Re:No such thing as 'autism' by wonkey_monkey · · Score: 1
    And your medical qualifications are... what, exactly? I'm going to take a wild stab in the dark at "non-existent."

    'Autism' is simply

    Wow, three words in and you've already got it wrong ;)

    --
    systemd is Roko's Basilisk.
  9. Re:No such thing as 'autism' by wonkey_monkey · · Score: 1

    PS Should have said this in the post above, but if anyone mods the GP down, feel free to mod my posts down too so even less people see this.

    --
    systemd is Roko's Basilisk.
  10. Re:No such thing as 'autism' by Anonymous Coward · · Score: 2, Informative

    Seriously, and with all due respect, fuck you very much.

  11. Re:If bad thriller movies have taught us anything. by Coppit · · Score: 1

    Where do I sign up?

  12. Autistic brains aren't made of wires by Culture20 · · Score: 1

    They're made of neurons. There's no wiring involved.

  13. There is no such thing as autism or "aspbergers" by Anonymous Coward · · Score: 1

    They are curse words used by idiots to describe what used to be called "nerds" or "geeks" or "Poindexters". These fake diseases need to stop. Seriously. Stop hiding between made-up bullshit diseases. I'm probably going to be called an "ass-pie" or "assburger" now, but... no. I suck at attracting females and a bunch of other social things, but there is no need to label that with a disease. I am fully aware of it and don't try to hide it. I don't need a fictional "condition" to hide behind.

    The worst, however, are people who proudly announce themselves to have these fake "diseases". They are even worse than the dumb people who use them as insults.

    +5, Insightful

  14. Re:No such thing as 'autism' by Earl_Parvisjam · · Score: 1

    Wow, you sir or madam are a piece of work. Your entire stance is based on prejudicial opinion and a book from 1967. Your concept of the terms "fact" and "truth" is intriguing and your use of a character attack right after mentioning logical fallacies is brilliantly timed; assuming you are trolling.

    At least you have the temerity to post as anonymous. It helps clarify how much we should care about your opinion, while illustrating just how serious you are about a subject you have no idea about. I thought the vaccine blaming crowd was bad...

  15. Re:If bad thriller movies have taught us anything. by O('_')O_Bush · · Score: 2

    Or... as the previous attempts at rewiring the brain did.... lobotomies.

    --
    while(1) attack(People.Sandy);
  16. Re:If bad thriller movies have taught us anything. by JoeMerchant · · Score: 1

    Oh you pretty things (oh you pretty things)
    Don't you know you're driving your
    Mamas and papas insane
    Oh you pretty things (oh you pretty things)
    Don't you know you're driving your
    Mamas and papas insane
    Let me make it plain
    You gotta make way for the homo superior

    David Bowie 1971

  17. Patched over is not repaired by Anonymous Coward · · Score: 4, Interesting

    Posting as AC, since I don't want my employer to read this.

    I have been diagnosed with aspergers. Anyone I have encountered in over 40 years on this planet that has any form of autism, mild or not, has to use their conscious brain functions to "patch" what "neurotypicals" have woven into their subconscious brain. People that think they are "superior to neurotypicals" in general don't realize what the part is they are missing. They are mistaking a high IQ for superiority while in practice, people with lower IQs as themselves but not with autism, tend to be more successful in life; in procreation, in happiness and in fortune.

    Sure, their higher IQs may make them "better citizens", but their high IQ and the decisions they make because of that, are not directly because of their autism. There are plenty of people with autism that don't have a high IQ, they get diagnosed with other forms like "classical autism" because they lack the brain power to consciously pick up the lack of social adaptation. This is a classical case of correlation is not the same as causation. I'm getting tired of those autistic people thinking they are superior just because they (once again) fail to see the point of social skills. The ones claiming this are usually not independently wealthy happy fathers, but rather single male workforce people that have individualistic jobs with no leadership requirements. Very few are female, but other than the single bit, they tend to be rather unhappy and not incredibly well off.

    Regarding the OT, I am skeptical about actual repair. I do hope it is possible since it takes a lot of energy to get by in normal life, even if you are "well adapted" like I classify. However, I think that if you only look at behavioral results, you may mistake conscious learning and decision making for actual instinctive behavior. Further testing will have to be done before claims should be made.

  18. Re:No such thing as 'autism' by TapeCutter · · Score: 1

    I feel your suffering, now if you would just let those who know what they are talking about rearrange some of your brain wiring, we would all be in a lot less pain.

    --
    And did you exchange a walk on part in the war for a lead role in a cage? - Pink Floyd.
  19. Re:Asperger by mrbester · · Score: 1

    But isn't putting additives in fuel the same as prescribing supplements / drugs to correct a perceived flaw? My engine is fine, does what it was designed to do and does it well. It wasn't designed for urban pootling in low gear, unless I give it drugs to "correct" this "problem" (quoted because it isn't a problem that needs correcting in my opinion; it's my car, not some focus group's)

    --
    "Wait. Something's happening. It's opening up! My God, it's full of apricots!"
  20. Re:Is that a good trade? by TaoPhoenix · · Score: 1

    "If you gain social intelligence at the cost of creativity, have you been improved? If you can suddenly understand the opposite sex and get them to sleep with you quickly, but no longer do (basic) math in your head, is that a good trade?" Notice the word Basic. Let's change that to "Complex".

    Maybe, and this is in a sense exactly what the Autism *spectrum* is all about. A word from the New Age lit is useful here: Esoteric. Autistic people often tend to like esoteric things. The word has connotations of "obscure but with mystique wrapped in with it". Looking at the item I re-quoted, what "Creativity" are we referring to? Nice, socially understandable Creativity like a nice song? Or living in a room where the spatial layout of everything is symbolically congruent to the XOR of observed behavior in a particular bee hive and a particular ant hill that the person studied and recorded? Isn't that "Creative" too? Sure it is. But doing XOR insect calculations in your head doesn't help you in a conversation with a budding romantic partner.

    So suppose the autistic person can do seven different types of that kind of creativity. None of them help with a date. He might indeed be willing to trade those kinds of calculations for "slowing down" and "magically" seeing better social results.

    --
    My first Journal Entry ever, in 8 years! http://slashdot.org/journal/365947/aphelion-scifi-fantasy-horror-poetry-webzine
  21. Autisim is not universally thought to be miswiring by Theovon · · Score: 1

    There is a huge contingent of medical practitioners, particularly nutritionists, who believe that ASD symptoms are the result of the liver being inadequate to filter toxins from the blood. Diet modifications have been documented to alleviate many ASD symptoms.

  22. And then we were six. by tlambert · · Score: 1

    Just saying.

  23. Gut Bacteria by nanospook · · Score: 1

    Here is an interesting article on Gut Bacteria in the Economist.. Autism is mentioned as well.. worth a good read.. http://www.economist.com/node/21560523

    --
    Have you fscked your local propeller head today?
  24. On a related note.. by tlambert · · Score: 1

    There is a huge contingent of medical practitioners, particularly nutritionists, who believe that ASD symptoms are the result of the liver being inadequate to filter toxins from the blood. Diet modifications have been documented to alleviate many ASD symptoms.

    How is that colon cleanse going? Solved your heavy metal problems yet?

  25. Re:Is that a good trade? by JoeMerchant · · Score: 2

    So suppose the autistic person can do seven different types of that kind of creativity. None of them help with a date. He might indeed be willing to trade those kinds of calculations for "slowing down" and "magically" seeing better social results.

    He might, one definition/distinction I read between autism and Aspergers was that a true autistic wouldn't care, where an aspie would give anything to be "more normal."

    Diversity is strength, suppression of diversity has led to some dark places.

  26. Re:No such thing as 'autism' by Relayman · · Score: 1

    But you did such a nice job of putting him in his place!

    --
    If I used a sig over again, would anyone notice?
  27. Re:There is no such thing as autism or "aspbergers by Relayman · · Score: 1

    You sound jealous! It's just too bad not everyone can be HFA.

    --
    If I used a sig over again, would anyone notice?
  28. Treatment Walks a Tightrope by Slashdot+Parent · · Score: 1

    Great, now we'll be able to fix all of them! We really need that! /sarcasm

    I for one find this very offensive. It's like telling all autistics they're malfunctioning.

    Parent of ASD-diagnosed kid here.

    You raise a good point. My wife and I recognize that we're walking a bit of a line in treating him. There are definitely those who subscribe to "The Einstein Syndrome", arguing that when you have a son of a computer geek and a banker, he just may be a little reclusive (I use that word, because it goes beyond being introverted), and that's fine. He's not broken. I see their point.

    On the other hand, humans are social animals. Reclusive people are mostly unhappy, and Einstein was ridiculed mercilessly as a child. Maybe that's why he spent so much time reading physics texts and not interacting with his peers? The happiest and most content people seem to be to be the ones who have warm relationships with family and friends. Not the smartest or richest or anything else.

    We decided to treat our son, from about age 1.5, with some pretty intense play therapy (no medication or anything like that). We immersed his entire life in progressively more abstract symbolic thought, under the guidance of his behavioral therapist. The entire process was amazing to watch. It really did seem to be building a part of this brain that he wasn't using before.

    Some observations:

    1. He absolutely loved the play therapy. Loved it. Loved the therapist. Loved his growing ability to create a new world inside his mind.
    2. He first started learning about past & future, as opposed to everything being in the present, by looking forward to seeing his therapist.
    3. After each session, either in-office or at-home, he was completely exhausted. The workout that we were giving his brain was clearly very intense for him.
    4. Early detection and treatment is definitely the way to go, if at all possible. Much easier to build brain function than to try to modify it later on. Also, sidesteps the "you're broken" factor because you're just stimulating brain development, and who can find fault in that?
    5. He is now an extrovert, which I find to be completely hilarious because I love irony. The kid who always sat in a corner alone, banging his head on the floor over and over and over again all day long now lights up a room when he enters.
    6. At this point, you would never guess what he was like as a toddler. The head-banging. The routines. The rigidity. The literal/mechanical nature (a toy truck was not a toy for him, it was a hunk of plastic with wheels to spin.. and spin... and spin... and spin... and spin.. and god help you if you tried to interrupt the spinning...).

    Looking back, I believe that we did the right thing for him. Like I said, humans are social creatures. It was important to us to try to make him more balanced.

    --
    They don't grade fathers, but if your daughter's a stripper, you fucked up. --Chris Rock