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Roundup Tolerant GM Maize Linked To Tumor Development

New submitter spirito writes with this snippet about rats fed Roundup laced water: "The first animal feeding trial studying the lifetime effects of exposure to Roundup tolerant GM maize, and Roundup, the world's best-selling weedkiller, shows that levels currently considered safe can cause tumors and multiple organ damage and lead to premature death in laboratory rats, according to research published online today by the scientific journal Food and Chemical Toxicology. ... Three groups were given Roundup in their drinking water, at three different levels consistent with exposure through the food chain from crops sprayed with the weedkiller: the mid level corresponded to the maximum level permitted in the US in some GM feed; the lowest corresponded to contamination found in some tap waters. Three groups were fed diets which contained different proportions of NK603 – 11%, 22% and 33%. Three groups were given both Roundup and NK603 at the same three dosages. The final control group was fed an equivalent diet with no Roundup or NK603 but containing 33% of equivalent non-GM maize." The Chicago Tribune reports that not everyone's convinced of the results: "Experts not involved in the study were highly skeptical about its methods and findings, with some accusing the French scientists of going on a 'statistical fishing trip.'"

32 of 356 comments (clear)

  1. How to Attribute a Newspaper by Electrawn · · Score: 4, Informative

    All right, we get sick of Slashdot editor bashing, but this needs to be addressed.

    The link to the Chicago Tribune is from a Reuters newsfeed. The attribution should be to Reuters, via Chicago Tribune.

    For quick reference, any "feed" stories from tribune company are going to have "sns" in the title. Other papers will vary.

    (From a former Tribune Co. Employee).

    1. Re:How to Attribute a Newspaper by Anonymous Coward · · Score: 5, Funny

      Poor editing for comedy is really the only reason I keep coming back. Try not to spoil that.

    2. Re:How to Attribute a Newspaper by zero.kalvin · · Score: 5, Insightful

      I am more concerned about the original paper ( which is no where to be found ) then proper newsfeed and what not.

  2. Awful headline. by Anonymous Coward · · Score: 5, Informative

    The headline suggests that GM corn causes cancer. This is ludicrous and only feeds the ignorant paranoid anti-GM crowd.

    It's ROUNDUP exposure that's linked to tumors - NOT genetic modifications. I am not at all surprised.

    I've been saying for years that there is nothing particularly risky about GM foods - it's dumping horrendous of herbicide on things that's risky... this is obvious to me, but not to the ignorant masses.

    Don't give the freaks ammunition, please.

    1. Re:Awful headline. by binarylarry · · Score: 5, Funny

      In other news, Monsanto has patented cancer.

      Joe Baggaleducia, Monsanto Chairperson, said "Monsanto is tired of users benefiting from the use of our proprietary cancer implementation and we're going to be pressing the matter in the courts soon. We don't care if you're old, young, or dying. You will be paying your $599 Monsanto CancerPlus fee, you cock smoking tea baggers. Show me the money!"

      Mr Baggaleducia then stripped naked and jumped into the giant money pit he recently had installed inside his tropical home in the Caymens. A Monsanto Spokesman was not available for comment.

      --
      Mod me down, my New Earth Global Warmingist friends!
    2. Re:Awful headline. by Znork · · Score: 4, Informative

      Of course, since the purpose of the GM in the case of roundup resistant strains is to be able to bathe the GM plants in roundup, it could be argued that only the GM corn will give you roundup related cancer, the non-resistant corn would be dead long before you could eat it.

    3. Re:Awful headline. by o'reor · · Score: 5, Insightful
      Wrong. TFA says:

      Researchers found that NK603 and Roundup both caused similar damage to the rats' health whether they were consumed on their own or together.

      (emphasis mine)

      So even without spraying Roundup on it, the GM crop increases the occurences of cancers.

      --
      In Soviet Russia, our new overlords are belong to all your base.
    4. Re:Awful headline. by SoulMaster · · Score: 4, Insightful

      You know, as I was RingTFA, I was trying to figure out how the reporter didn't mention Monsanto at all. Seriously, your quote is modded funny, but not including the fact that Monsanto owns (and TIGHTLY controls) both in the article seems to be a significant oversight on the part of the press.

      -SM

    5. Re:Awful headline. by dbet · · Score: 5, Informative

      The paper

      They don't go into detail about how the Roundup is exposed. In previous studies, they use adjuvants to help with delivery, which can increase toxicity. But they say nothing in this paper. They also don't control dietary intake. What if GM corn is tastier and they're eating more? Or less?

      Furthermore, they observe the same health effects in the roundup group, the GM corn group, and the GM+R (both) group, AND these effects are not dose-dependent. Combine this with the small sample size, and the fact they're using a tumor-prone rat breed, you have a paper that's going to be crucified by peer review.

      As of today, there is no citation for this paper by Food and Chemical Toxicity which means... I don't know. But it hasn't been published yet. Was this leaked during peer review process? This stinks and everyone should withhold judgement.

    6. Re:Awful headline. by Sir_Eptishous · · Score: 4, Interesting

      Meat, especially Beef is the real problem.

      It's only a matter of time until the resources required to create meat get stressed to the point of pricing it out of most peoples diet. The fact that the developing world, especially China, is increasing the amount of meat in its diet will only increase the problem and quicken the change.

      The American Fast Food Industrial Complex that has led the way in shaping the American diet and it's addiction to Beef will have to re-shape the American diet towards vegetarianism.

      --
      We play the game with the bravery of being out of range
    7. Re:Awful headline. by o'reor · · Score: 4, Informative
      Hah. Now that's a good question. Actually, the researcher told the french press that he had to smuggle those seeds from a canadian farming school, since Monsanto won't let anyone do any research on its plants without having total control over the outcome of the research.

      After he got the seeds, I suppose he was able to grow two crops, one exposed to Roundup, and the other pesticide-free.

      --
      In Soviet Russia, our new overlords are belong to all your base.
    8. Re:Awful headline. by Solandri · · Score: 4, Informative

      It's sad, but we have limited amounts of fields and only so many resources(in dollar equivalents).

      We have plenty of fields. The U.S. produces an oversupply of food each year, and has to figure out ways to get rid of the excess (foreign aid, high fructose corn syrup, cattle feed, corn ethanol). The reason is because we implemented policies to ensure overproduction, to avoid a repeat of the food shortages which followed the Dust Bowl in the 1930s. And population growth in Canada and the U.S. is less than one percent a year, trending towards zero growth. There is no need to maximize yield per acre here, just a profit incentive to do so.

      The vast majority of the world's population growth is in third world countries. Developed nations all have population growth rates near zero or even negative. There's something about living in a modern post-industrialized economy which makes people want to have fewer kids. So the solution to feeding the burgeoning world population isn't to maximize yield per acre. It's to assist those third world countries in developing their economies so they too can become post-industrialized nations. If you instead concentrate on making more food, that population growth will just continue a vicious cycle of poverty and high population growth, until starvation and fighting over food finally caps it.

  3. Re:Did they study the health effects of starving? by crazyjj · · Score: 5, Insightful

    Actually the economically advantaged are the ones buying the organic everything.

    FTFY.

    --
    What political party do you join when you don't like Bible-thumpers *or* hippies?
  4. Dangerous poison. by Anonymous Coward · · Score: 5, Funny

    1. Analyze a dangerous poison.
    2. Modify a crop's genes to be resistant against said dangerous poison
    3. Treat modified crop liberally with dangerous poison
    4. Have cattle eat crop treated with dangerous poison
    ???
    6. Be amazed at what the poison does to non-resistant life forms.

    1. Re:Dangerous poison. by fustakrakich · · Score: 5, Funny

      They should modify the peoples' genes, so they can eat the Roundup directly without having to bother with that silly ol' corn.

      --
      “He’s not deformed, he’s just drunk!”
    2. Re:Dangerous poison. by vlm · · Score: 5, Informative

      1. Analyze a dangerous poison.

      LOL. Glyphosate kills anything that makes its own tyrosine, tryptophan and phenylalanine. People supposedly cannot synthesize it we can only eat it. Much as oxygen will kill some anaerobic bacteria, it would be a huge shock to discover oxygen causes cancer in people.

      A quick "chemists glance" at the MSDS and its about as scary as rubbing alcohol... I would not drink it or wash my hands in it before eating, but I wouldn't freak out either. Everything in a chemistry lab is dangerous, you have to put it in a spectrum, and this is worse than the distilled water but pretty much obviously on the safe edge of the spectrum compared to everything else in a lab. Some of the problem is the solvents and stuff the herbicide is dissolved into to spread it around. I heard there was a court case where some PR clown called it as safe as table salt, which although technically true is misleading because your body has perfectly adequate although extremely unpleasant ways to remove a lethal salt dose from your body, unless you somehow stop it or inject it all at once. Calling it as safe as rubbing alcohol would have been about as true and less likely to get sued.

      Its pretty laughable that glyphosate is a "dangerous poison". Try some organic mercury compounds if you want real danger. Its not even useful for biowarfare, not persistent enough, its highly biodegradable. Which mystifies me... so if it all degrades worst case in 100 days, and twinkie sits on the shelf for 4 months before its eaten, how is anyone eating the stuff? Yeah, I know, field to table salad without rinsing or washing, but that doesn't fit the meme of all american diets being hyper processed.

      The other funny part is its use will be a footnote in history "soon". Too many resistant weeds are spreading. Why spend big bucks to apply something that'll do nothing. Why agitprop to ban something that no one will want to manufacture pretty soon, anyway?

      --
      "Science flies us to the moon. Religion flies us into buildings." - Victor Stenger
    3. Re:Dangerous poison. by o'reor · · Score: 5, Interesting

      Actually, glyphosate is dangerous for plants only. However, the molecule has to find its way across the cell walls of the plant. So Monsanto added surfactant agents to break into the cells, so that the glyphosate could enter the plant. And those are *really* dangerous.

      --
      In Soviet Russia, our new overlords are belong to all your base.
  5. Re:Did they study the health effects of starving? by interkin3tic · · Score: 4, Interesting

    False dichotomy. No one is saying we must ban everything that gives you cancer.

  6. Re:Did they study the health effects of starving? by cplusplus · · Score: 4, Insightful

    Ever watched someone die of cancer? You might change the tune of your somewhat crazy rant if you had. The article states that "Up to 50% of males and 70% of females died prematurely" showing "2-3 times more large tumors than the control group" - which is somewhat disconcerting. If those numbers translate to what will be observed in the human population (which they probably won't, as this study was done with the upper bound tolerated limits in food, although consistent with what could be found in the food chain), then guaranteeing food for people now with the promise of a horrible premature death later doesn't sound like a good compromise.

    --
    "False hope is why we'll never run out of natural resources!" - Lewis Black
  7. The end is near! (Really) by judoguy · · Score: 5, Interesting
    I have a friend that's a food researcher at a large Midwestern university. He's not opposed to Roundup per se, but rather the *massive* use of it on vast areas of monoculture.

    He says that this is guaranteed to produce Roundup impervious weeds. At some point these super weeds will need very toxic chemicals to kill. The real problem is that vast areas of monoculture are unsustainable.

    Nature abhors a vacuum and will fill it up with what can tolerate the environment.

    --
    Peace is easy to achieve, just surrender. Liberty is much harder get/keep.
  8. Giant Ragweed by sir_eccles · · Score: 5, Informative

    You know what has also become Roundup resistant? Giant ragweed.

    http://www.bbc.co.uk/news/science-environment-19585341

  9. Re:Did they study the health effects of starving? by MightyYar · · Score: 4, Interesting

    I always enjoyed the sight of people coming out of the Union Square Whole Foods in NYC with organic groceries. Because the smog, heavy metals, and road traffic exhaust of Manhattan won't give you cancer, but that trace amount of pesticide sure will.

    To be fair, they do have above-average produce.

    --
    W..w..W - Willy Waterloo washes Warren Wiggins who is washing Waldo Woo.
  10. Re:Did they study the health effects of starving? by c · · Score: 4, Funny

    Actually the economically advantaged are the ones who think they're buying the organic everything.

    FTFY.

    FTFY.

    --
    Log in or piss off.
  11. Re:Did they study the health effects of starving? by mcgrew · · Score: 4, Informative

    Yeah, we should ban evil pesticides! Down with evil chemicals and modern GM farming! Organic all the way!

    True to your user name, I see. Nobody has sugested that all pesticides are bad or that we should return to the 19th century. You do realize that there were no tractors back then, let alone harvesters or combines?

    This one strain of corn is what's under discussion, and it looks like it should be banned... if the methodology of its studies hold up. Which it looks as if they may not.

  12. Re:Did they study the health effects of starving? by pepty · · Score: 4, Interesting
    FTA:

    The article states that "Up to 50% of males and 70% of females died prematurely" showing "2-3 times more large tumors than the control group"

    FT (other) A:

    Tom Sanders, head of the nutritional sciences research division at King's College London noted that Seralini's team had not provided any data on how much the rats were given to eat, or what their growth rates were. "This strain of rat is very prone to mammary tumors particularly when food intake is not restricted," he said in an emailed comment. "The statistical methods are unconventional and probabilities are not adjusted for multiple comparisons. There is no clearly defined data analysis plan and it would appear the authors have gone on a statistical fishing trip."

  13. Re:Did they study the health effects of starving? by similar_name · · Score: 4, Insightful

    Maybe we should start with people who destroy any chance of reasonable debate by boiling down every argument to two extremes.

  14. Re:Did they study the health effects of starving? by SomePgmr · · Score: 4, Interesting

    I'm the first to admit that I'm no expert on this stuff, but this sounds pretty damning...

    Tom Sanders, head of the nutritional sciences research division at King's College London noted that Seralini's team had not provided any data on how much the rats were given to eat, or what their growth rates were.

    "This strain of rat is very prone to mammary tumors particularly when food intake is not restricted," he said in an emailed comment.

    "The statistical methods are unconventional and probabilities are not adjusted for multiple comparisons. There is no clearly defined data analysis plan and it would appear the authors have gone on a statistical fishing trip."

    Mark Tester, a research professor at the Australian Centre for Plant Functional Genomics at the University of Adelaide, said the study's findings raised the question of why no previous studies have flagged up similar concerns.

    "If the effects are as big as purported, and if the work really is relevant to humans, why aren't the North Americans dropping like flies? GM has been in the food chain for over a decade over there - and longevity continues to increase inexorably," he said in an emailed comment.

  15. Re:Did they study the health effects of starving? by dbet · · Score: 4, Insightful

    Then we better ban sunlight.

    Calling Mr. Burns!

  16. Re:Did they study the health effects of starving? by kelemvor4 · · Score: 4, Interesting

    In that case I think banning GM foods would have a much smaller impact that you suppose. Commercial sale of genetically modified foods began in 1994 (source: https://en.wikipedia.org/wiki/Genetically_modified_food ). Not that I'm suggesting they need to be banned. I'm for mandatory labeling of products and detailed government sponsored scientific studies on the topic. If the problem was eliminated (or significantly reduced) before 1994, then GM crops and round-up did not play a role.

  17. Re:Did they study the health effects of starving? by sjames · · Score: 4, Informative

    The same strain of rat was used in the controls and fed the same way (just a different variety of corn) and didn't get the tumors.

  18. Re:Did they study the health effects of starving? by gardenermike · · Score: 5, Informative

    Way, way off. The numbers are more like a 30% decrease in yields, based on current farming methods. Considering that we haven't applied science to organic farming like we have to chemical farming, due to easy postwar chemical availability, the gap could probably be closed even more. Yes, conventional farms have marginally higher productivity. But you are off by an order of magnitude with your "5x" claim.