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Designing DNA Specific Bio-Weapons

Hugh Pickens writes writes "The Atlantic reports that experts in genetics and microbiology are convinced we may be only a few years away from the development of advanced, genetic bio-weapons able to target a single human being based on their DNA. The authors paint a scenario of the development of a virus that causes only mild flu in the general population but when the virus crosses paths with cells containing a very specific DNA sequence, the sequence would act as a molecular key to unlock secondary functions that would trigger a fast-acting neuro-destructive disease that produces memory loss and, eventually, death. The requisite equipment including gene sequencers, micro-array scanners, and mass spectrometers now cost over $1 million but on eBay, it can be had for as little as $10,000. According to Ronald Kessler, the author of the 2009 book In the President's Secret Service, Navy stewards gather bedsheets, drinking glasses, and other objects the president has touched—they are later sanitized or destroyed—in an effort to keep would-be malefactors from obtaining his genetic material. However no amount of Secret Service vigilance can ever fully secure the president's DNA, because an entire genetic blueprint can now be produced from the information within just a single cell. How to protect the President? The authors propose open-sourcing the president's genetic information to a select group of security-cleared researchers who could follow in the footsteps of the computer sciences, where 'red-team exercises,' are extremely common practices so a similar testing environment could be developed for biological war games. 'Advances in biotechnology are radically changing the scientific landscape. We are entering a world where imagination is the only brake on biology,' write the authors. 'In light of this coming synbio revolution, a wider-ranging relationship between scientists and security organizations—one defined by open exchange, continual collaboration, and crowd-sourced defenses—may prove the only way to protect the president.'"

8 of 227 comments (clear)

  1. Frank Herbert's The White Plague by Lundse · · Score: 5, Informative

    Just throwing that out there... Basic scenario; brilliant biochemist does exactly this to wreck revenge on Ireland and England for the conflict that took his family. Mild flu in males, deadly to females. Some of his best work outside Dune, btw...

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  2. What a great thing. by Z00L00K · · Score: 5, Insightful

    For every interest group when they figure out that they can target "unwanted" groups of people. And imagine what the Nazis of Germany could have done during WWII - a virus designed to kill off everyone that wasn't pure Arian.

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  3. I had to cringe by Anonymous Coward · · Score: 5, Insightful

    We haven't yet found a cure for cancer, or other horrible and debilitating diseases, but we've found time to research something like this?

  4. Collecting DNA by OzPeter · · Score: 4, Interesting

    If I was a foreign power wanting to build a genetic weapon to specifically target the President, I would haver been collecting the DNA of all the top echelon politicians well before they came close to running their presidential campaigns. If I can think of this in 10 seconds of reading TFS (not even TFA) then I'm sure that the bad guys have already thought of it - unless you subscribe to the theory that the bad guys are always dumb.

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    1. Re:Collecting DNA by OzPeter · · Score: 4, Funny

      Considering how dumb our bad guys are, I wouldn't be sure of anything. :)

      Can't we have any discussion without mentioning the current Presidential election?!?!?!?

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  5. Produces memory loss? by Anonymous Coward · · Score: 5, Funny

    It seems that they are already attacking our politicians with this method, since they never seem to be able to remember anything they said before they were elected.

  6. Re:I hate it by Custard+Horse · · Score: 5, Funny

    A bullet would be more humane than to cause an eventual death by progressively shutting down their body.

    You've just described old age. You do know that Logan's Run is not a documentary right?

  7. what could POSSIBLY go wrong? by v1 · · Score: 4, Interesting

    We're already very aware of how viruses constantly mutate. So, how long before this one mutates such that the "switch" is always in the "ON" position, and then proceeds to wipe out most of the human population?

    BRILLIANT idea. brilliant. It's these sorts of mad scientists that truly scare me.

    Add to that, there's no "kill switch" if you have a problem. Anyone caught making a virus weapon needs to die by fire. Along with the ones that funded and assisted them. The whole world needs to be completely clear about this, because it's a serious danger to every living soul.

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