Slashdot Mirror


China's Controversial Brain Surgery To Cure Drug Addiction

kkleiner writes "A small handful of doctors in China are using a highly controversial procedure to rid people of drug addiction by destroying a part of patients' brains. The procedure involves drilling small holes into the skulls of patients and inserting long electrodes that destroy a part of the brain called the nucleus accumbens. This area, often referred to as the "pleasure center" of the brain, is the major nucleus of the brain's reward circuit. Is it worth being cured of addiction if, losing the addiction, we also lose part of who we are?" The practice has been officially banned, but apparently continues nonetheless.

40 of 385 comments (clear)

  1. 21st Century Lobotomies by Anonymous Coward · · Score: 5, Insightful

    They worked out so well last time.

    1. Re:21st Century Lobotomies by Charliemopps · · Score: 3, Interesting

      They did work out well in the past. It's easy to call treatments of the past barbaric without perspective. Often those treated with labotomies would have spent the rest of their lives in strait jackets or worse if not for the treatment. If your drug addiction is going to kill you in the next 6 months is this treatment really that terrible? Granted, governments always take this sort of thing too far "he's addicted to MMOs!" etc...

    2. Re:21st Century Lobotomies by Kjella · · Score: 3, Interesting

      They did work out well in the past. It's easy to call treatments of the past barbaric without perspective.

      Not to mention the basic ideas of lobotomy are very much alive, I knew a guy with very severe epilepsy attacks. I think the surgery he had was something like this:

      Multiple subpial transaction

      This is used when it's not possible to remove the part of the brain that's causing the seizures. The surgeon will make a series of cuts to help separate the damaged part of the brain from the surrounding area. This stops seizures from moving from one part of the brain to other parts of the brain.

      He was in his 30s and that enabled him to finally move out of his parent's house, get a bit of education and a driver's license. It didn't come without downsides but overall he was much, much better off than before.

      --
      Live today, because you never know what tomorrow brings
    3. Re:21st Century Lobotomies by EdIII · · Score: 3, Interesting

      Well, in this case, the patient is just doing it to themselves depending on the situation.

      What I understand about meth and brain chemistry is that over time a meth addict is saturating the pleasure center of their brain. The structures that pick up the neurotransmitters actually become damaged or less effective over time.

      This is why a lot of meth addicts will say the only way they can feel happiness is with the drug. Recovered meth addicts often complain that they have very serious issues feeling happy anymore.

      How long that takes to heal, I dunno.

      The end result of disabling the pleasure center may be inevitable. At least doing it in the beginning may be a way to get them stop completely and literally save their lives and increase the overall quality from a health standpoint alone. They may become emotionless, but can still live otherwise.

      Just my two cents. I'm not a doctor. Just know some very unfortunate recovered drug addicts that have more in common with Vulcans now than humans.

  2. Is it worth? by XiaoMing · · Score: 5, Funny

    is it worth being cured of addiction if, losing the addiction, we also lose part of who we are? Is it worth being cured of addiction if, losing the addiction, we also lose part of who we are?

    is it worth reading slashdot, if, reading it means reading poorly edited summaries like these? Is it worth reading slashdot, if, reading it means reading poorly edited summaries like these?

    1. Re:Is it worth? by Cryacin · · Score: 4, Funny

      I guess the person who wrote the summary was speaking from experience.

      --
      Science advances one funeral at a time- Max Planck
    2. Re:Is it worth? by Anonymous Coward · · Score: 5, Funny

      Jesus here. Stop telling me what I already know.

  3. Lost a Friend Yesterday by BoRegardless · · Score: 5, Interesting

    Couldn't control his drug issues. His birth mother was addicted.

    Now he is gone. Would he have been better served to still be here w/o some "reward center". I don't know. I will never know.

    1. Re:Lost a Friend Yesterday by Anonymous Coward · · Score: 5, Interesting

      Would he have wanted to live if he never found any joy in living ever again?

    2. Re:Lost a Friend Yesterday by GameboyRMH · · Score: 4, Insightful

      if you were circumcised and can't feel pleasure from your penis then something went horribly, horribly wrong with the procedure. That's definitely not normal. I'm circumcised so I know what I'm talking about.

      --
      "When information is power, privacy is freedom" - Jah-Wren Ryel
    3. Re:Lost a Friend Yesterday by Velex · · Score: 4, Interesting

      Yes, something did go horribly wrong. Unfortunately, nobody's cared to understand non-obvious failure modes of that procedure. So, nobody thought that anything could go wrong when they decided to do it, at least not anything non-obvious that can not be corrected by further surgery. It didn't stop it from going wrong, though.

      In fact, when I started estrogen HRT (I'm transgendered) I asked my doctor about it just to make sure I wasn't making some awful mistake. His theory was that it was only because it seemed that my brain was female, and he postulated that a female brain might not, to put it in slashdot speak, have the proper device driver for it all to work right. Unfortunately, nobody told my doctor that what happened to me is possible. I'm not even sure I'm faulting circumcision correctly, but what I do know is what I feel, that I'm circumcised, that problem is with the same body part involved in that, and that no other trans person I've met can corroborate my experience. (I would likely still be transgendered and seek estrogen HRT even intact--I believe that because there are intact trans women and I can't figure out what difference it would make anyway in that matter.)

      What do I do about it, though? I guess I have to wait until they can grow me a new one from stem cells and replace it. I'm SOL in the meantime. Fortunately, I found other ways to satisfy myself, so all's not lost. I just may never be successful in giving my parents grandchildren.

      I'm comparing this to circumcision to hopefully make readers think. Some may agree with circumcision but disagree with this brain surgery and vice-versa.

      I only meant to raise the question of what can possibly go wrong and is it worth it to risk the occasional disaster when something less invasive and traumatic, like relaxed drug laws and treatment, might solve the problem just as well or even better.

      --
      Join the Slashcott! Stay away entirely Feb 10 thru Feb 17! Close all tabs to prevent autorefresh!
    4. Re:Lost a Friend Yesterday by LordLimecat · · Score: 5, Insightful

      Losing a friend because he made bad decisions is tragic, and cause for grief. Having a friend lobotomized because the government has decided youre making bad decisions is horrifying, and cause for outrage.

      There is a big difference between making bad decisions freely, and having the government decide that you are no longer fit to make your own decisions.

    5. Re:Lost a Friend Yesterday by jamesh · · Score: 3, Insightful

      Losing a friend because he made bad decisions is tragic, and cause for grief. Having a friend lobotomized because the government has decided youre making bad decisions is horrifying, and cause for outrage.

      There is a big difference between making bad decisions freely, and having the government decide that you are no longer fit to make your own decisions.

      There is a grey area here Mr Black'n'White, and that's when your bad decisions hurt and kill other people. And I mean directly, not just like 'you shouldn't smoke because someone else will have to take care of you later on' and 'the hospital couldn't save your mother because they were busy dealing with an overdose', I mean because ice addicts are killing people in their violent rampages and other addicts are robbing people to feed their next hit. That's when it becomes the governments problem.

      And the whole definition of addition is that you are no longer fit to make your own decisions because your addiction is making them for you.

      I'm not quite sure lobotomy is the answer here, but it may turn out to be the best of the available options.

      I wonder if it's possible to just turn off that part of brain for a bit instead of destroying it...

    6. Re:Lost a Friend Yesterday by Mr.+Slippery · · Score: 3, Insightful

      I mean because ice addicts are killing people in their violent rampages

      Citation needed.

      and other addicts are robbing people to feed their next hit. That's when it becomes the governments problem.

      ...which is a consequence of prohibition, which drives up prices, and not of the drug itself. How many alcoholics do you see robbing people to feed their next hit? Addicts committing theft is a government-created problem.

      And suggesting that the government has the rightful power to forcibly and irreversibly modify the brains of citizens is disgusting and despicable. You should be ashamed of yourself, sir.

      --
      Tom Swiss | the infamous tms | my blog
      You cannot wash away blood with blood
    7. Re:Lost a Friend Yesterday by AdamHaun · · Score: 5, Insightful

      Mostly I was talking about the ACs, but let's talk about you. What BoRegardless said was:

      Now [my drug-addicted friend] is gone. Would he have been better served to still be here w/o some "reward center". I don't know. I will never know.

      This is not a statement of support. It is a statement of confused grief.

      After misinterpreting this as fervent support, you proceeded to speculate wildly about BoRegardless's motivations and his late friend's addiction, levy criticism based on that speculation, and recommend that he read a story about being trapped in a hellish existence where death is the only escape.

      In response to a person who just said that his friend had died. Yesterday.

      The article is talking about a surgery that is performed only in China, only for research purposes, and only with worldwide condemnation. The only debate outside of China is whether the results of that research should be published in respectable journals.

      Your comment did not address that debate. It will have zero effect on what happens in China. The only thing it does is attack and belittle someone who just lost a friend. In your zeal to put on a show of righteousness on the internet, you are stepping all over the real human being who is (metaphorically) right in front of you.

      To say that this lacks compassion would be an understatement.

      --
      Visit the
    8. Re:Lost a Friend Yesterday by Trillian_1138 · · Score: 3, Insightful

      Undoing some moderation, but wanted to chime in. I'm also a trans woman, and circumcised. As far as I can tell, my penis always worked fine. (Where 'fine' = 'got erect, ejaculated, functioned well enough for me to deposit sperm.') So far as I can tell, my being trans is unrelated to how well my genitalia does or doesn't function. Let me know if this responds to what you were curious about - I'd be happy to chat more.

    9. Re:Lost a Friend Yesterday by quantaman · · Score: 3, Insightful

      Would he have wanted to live if he never found any joy in living ever again?

      Speaking for myself (who doesn't have a drug addition), hell yes.

      Sure it's a reduced quality of life from ideal, but it's still life. Besides, there's a reason it's referred to as the "pleasure centre" and not the pleasure centre, the brain isn't that neatly divided, I'm sure they can still feel some kind of pleasure, and have other forms of satisfaction in life, but that particular reward mechanism won't function (at least not in the same way).

      --
      I stole this Sig
  4. I wouldn't mind losing part of who I am by Anonymous Coward · · Score: 5, Interesting

    When it comes to a real problem a change in personality wouldn't be such a problem, but losing dopamine forever? Never to feel positive emptions again ever? I don't care who you are that's not worth it. Surely the reason people get addicted to begin with is they don't have enough dopamine and serotonin in their life for whatever reason.

  5. Seriously editors by thegarbz · · Score: 4, Insightful

    FIX THIS SHIT!

    There's no more nice way to say it. This isn't a case of leaving the unit off a measurement, a simple typo, or even the ever so common case of a grammatical mistake a 10 year old could pick out.

    This is YOU timothy not bothering to read 111 words that you put in the summary, let alone edit them.

    Know what happens to me when I go to work and don't do any work, worse still I embarrass the company I work for? I get fired.

  6. Serious question by Firethorn · · Score: 3, Insightful

    The story sucks, but I have to wonder. We do some radical brain surgeries at times just to fix problems with seizures. At least in the long term addiction carries a higher incidental rate of death, lowered quality of life, and such than seizures.

    So I guess I'd have to say 'it depends'. I'd view it a bit the same as stomach stapling for weight loss -

    I'd need to know a heck of a lot more about the details of the surgery - primary effects, dangers, side effects, success rates, etc...
    Does it result in an unmotivated zombie, because there's no longer any reward for doing so much as life maintenance tasks? Can they still feel pleasure? Is it only being used on the most serious 'mental' addiction cases? I added mental because this wouldn't solve physical addictions to things like heroin, I think, but might help solve addictions to gambling, stealing, etc...

    Going by the article, it seems to only stop addictions 10% better than traditional methods, and is still well under half. 60% have serious side effects, so I'm going to go with 'nope, not worth it, keep looking'.

    As for 'losing who you are', well, even just day to day life you change. I'm not the same person I was a decade ago. Technically I'm not the person I was yesterday. If somebody wants to change, it might be worth it.

    --
    I don't read AC A human right
  7. Thanks, Minitrue! by Goaway · · Score: 5, Insightful

    The practice has been officially banned, but apparently continues nonetheless.

    Of course, we're not going to let that stop us from calling it "China's", as if it were some kind of official and mandatory procedure.

  8. Re:A small handful... by queazocotal · · Score: 3, Funny

    Even with the size of chinese doctors, I imagine one would be a large handful.

  9. The deeper questions are: by tiqui · · Score: 3, Interesting

    Are you truly who you think you are when you are addicted to drugs?

    Are the pleasures a drug-affected brain feels to be equated with other forms of pleasure?

    It would be one thing to wipe-out part of a healthy brain (thereby permanently altering it) like this but it might be another matter to make such a permanent change to a brain that has already had permanent, and negative, changes made by "modern chemistry". Of course, the presence of any pre-existing damage from drugs also raises questions of true consent. Not sure how I feel on this one, but given that this is on brains already affected by drugs the morals and ethics are a bit cloudier than they might otherwise be. Personally, I find the idea of depriving a person of the ability to experience pleasure both creepy and dangerous. Should we expect future headlines about "zombie" violence in China?

  10. Re:I'll auto-Godwin myself by MrHanky · · Score: 4, Informative

    Most of the West, the U.S. included, was big on this kind of "experimentation" (i.e. lobotomies as a kind of medical treatment) a few decades ago. No need for Hitler here.

    On a positive note, much of our current knowledge of how the human brain works comes from destruction of various kinds, either from intentional and misguided treatment or from strokes. The side effects are often interesting.

  11. ethics, schmethics. it's just outsourcing! by retchdog · · Score: 5, Interesting

    Dr. John Adler, professor emeritus of neurosurgery at Stanford University, collaborated with the Chinese researchers on the publication and is listed as a co-author. While he does not advocate the surgery and did not perform it, he believes it can provide valuable information about how the nucleus accumbens works, and how best to attempt to manipulate it. “I do think it’s worth learning from,” he says. ” As far as I’m concerned, ablation of the nucleus accumbens makes no sense for anyone. There’s a very high complication rate. [But] reporting it doesn’t mean endorsing it. While we should have legitimate ethical concerns about anything like this, it is a bigger travesty to put our heads in the sand and not be willing to publish it,” he says. cite.

    --
    "They were pure niggers." – Noam Chomsky
  12. Re:I'll auto-Godwin myself by GameboyRMH · · Score: 4, Insightful

    Yep the rest of the world only stopped with the eugenics, forced sterilizations and routine lobotomies because Hitler made them uncool.

    --
    "When information is power, privacy is freedom" - Jah-Wren Ryel
  13. Re:I'll auto-Godwin myself by WWJohnBrowningDo · · Score: 5, Informative

    The first transorbital lobotomy was performed in 1946, one year after Hilter's death.

    Lobotomies stopped being routine in the 70's.

  14. Re:I'll auto-Godwin myself by justin12345 · · Score: 4, Interesting

    No need to Godwin yourself. Checkout what the Canadians were up to (with a little funding from the CIA): http://en.wikipedia.org/wiki/Donald_Ewen_Cameron#Project_MKULTRA

    --
    Cool art gallery, if you're into that sort of thing.
  15. Meanwhile, in America... by Stormwatch · · Score: 3, Funny

    Meanwhile, in America, they do surgeries to remove a part of BABIES' PENISES.

    Pot, kettle, and all that shit.

  16. Re:I'll auto-Godwin myself by Internetuser1248 · · Score: 4, Informative

    The worst thing about this is that it is totally uneccesary. There was a study in the '60s that showed that targeted therapy in combination with psychedelic drugs can cure addiction with a very high success rate (compared to other methods) and almost no side effects. After lsd was made illegal research stopped but recently people have continued the program with ibogaine. The research is still far too preliminary for conclusive results but the fact that a potential treatment exists makes brain surgery even more inadvisable.

  17. Re:I'll auto-Godwin myself by Runaway1956 · · Score: 3, Interesting

    This is possibly the single worst thing that the Nazis did. They turned the world away from eugenics, because they were so cold hearted and calloused toward an entire race.

    In and of itself, eugenics is a good thing. I would love to see it advanced. The research could lead to the cures for cancer, diabetes, heart disease, possibly even make our entire race stronger and smarter. The possibilities are endless.

    But, because eugenics were so horrible abused by one group of people, against another group of people, we refuse to even look down that road.

    I don't suppose that science will advance on that frontier unless and until a significant portion of mankind has left mother earth. I just hope that by then, the researchers haven't forgotten the atrocities committed by the nazis. The memories must be preserved, or mankind risks repeating those same atrocities.

    --
    "Windows is like the faint smell of piss in a subway: it's there, and there's nothing you can do about it." - Charlie Br
  18. Abuses by betterunixthanunix · · Score: 4, Insightful
    Perspective? Lobotomy began with extremely careful scraping of the brain, meant to do the absolute minimum damage possible. Then some greedy quack in the USA took it to a ridiculous extreme, turning a nice young lady into a wheelchair-bound mess because her stuck-up family was worried about their social standing, and that soon degenerated into a procedure that should have been called a crime against humanity:

    https://en.wikipedia.org/wiki/Transorbital_lobotomy

    If your drug addiction is going to kill you in the next 6 months

    There are no certainties about that sort of thing, but there is a certainty about the sort of brain-damaging lobotomy described in TFA: it is irreversible and destructive.

    --
    Palm trees and 8
  19. Re:I'll auto-Godwin myself by Immerman · · Score: 3, Insightful

    Can't find it offhand, but there was an interesting TED talk a while back by a fellow who had received repeated ECT treatments. I forget the details, but the gist was that he had been a respected professor until he suffered a mental illness that sent his life spiraling into oblivion. When all the less radical treatments failed, ECT managed to fix the problem and he was able to rebuild his life. No argument that there have been some horrible abuses in the past, but it does seem that there are situations where it is in fact the best option available. As with *any* neurological treatment though, I think the consent of the patient is absolutely crucial - forcibly altering someone's mind without their consent seems to me to be about the worst form of rape imaginable.

    --
    --- Most topics have many sides worth arguing, allow me to take one opposite you.
  20. Re:I'll auto-Godwin myself by hairyfeet · · Score: 3, Insightful

    Actually I'd say they learned from the Japs, after all the Japs made the crazy Austrian look like a humanitarian when it came to human experiments. The worst part is unlike the Nazis we let most of the monsters left in Japan walk to get their data whereas with the Nazis we mainly went after the eggheads making rockets and jet engines, not the guys doing human testing.

    as for TFA we tried that kind of stuff before, it was called a lobotomy, made the symptoms go away alright and left a broken doll in place of a human being. We are talking about obliterating the pleasure center of the brain so they will NEVER feel pleasure again, i bet a good 70%+ end up committing suicide in 5 years or less. Hell it would be more humane to just take them out back and treat them with a 45cal to the back of the head.

    --
    ACs don't waste your time replying, your posts are never seen by me.
  21. Re:I'll auto-Godwin myself by hairyfeet · · Score: 4, Insightful

    "Well I believe the puppet on the left shares MY beliefs, well I believe the puppet on the right has MY interests at heart...hey wait a minute, there is one guy controlling both puppets!"...Bill Hicks. The man has been gone more than 20 years and its even more true now than it was back then.

    I urge all of those who think "If only my party got control things would be better" to watch the truth about voting and ask yourself some simple questions like : How many decades have been people voting for less government intrusion? less war? Less handing out billions to third world thugs? hell how many years have we been complaining and voting about the horribly broken borders? the corruption? the influence of lobbyists?

    At the end of the day you can NEVER change a corrupt system by working within that system, why? Well the answer is obvious, its corrupt! That would be like handing a petition to some corrupt police force demanding they stop taking bribes...why would they care what you think? Like pro wrestling its all kayfabe and thanks to the revolving door between the corps and government today's senator will be tomorrow's lobbyist so by voting him out all you are doing is giving him a pay raise while letting someone else get a shot at the money!

    --
    ACs don't waste your time replying, your posts are never seen by me.
  22. Re:I'll auto-Godwin myself by disambiguated · · Score: 3, Interesting

    I'm not in favor of forced sterilization, but at least the person would have other reasons to go on living.

    But I must be missing something here, because shouldn't the question be:

    Is it worth it to cure addiction if you utterly destroy everything that makes life worth living?

    How could any rational person think this is a good idea?

  23. Re:I'll auto-Godwin myself by Smauler · · Score: 4, Funny

    I agree. The 16 year old girl who has sex with her 15 year old boyfriend should be sterilized, and part of her brain should be destroyed.

  24. Re:I'll auto-Godwin myself by TFAFalcon · · Score: 4, Insightful

    But if you think about this it's actually a pretty lousy argument. It makes your conception the most important fact in history. Think how many other IFs you could justify just to make yourself happen. 'If your mother hadn't been raped, you wouldn't have happened. If your father hadn't had one of his balls shot off you wouldn't have happened. If Hitler hadn't existed your parents wouldn't have met. If Nagasaki hadn't been bombed the celebration of the end of the war would have been a day later so you wouldn't have happened,.......' Once you start thinking like that EVERYTHING that happened becomes a good thing, since it resulted in the miracle of YOU. So why not look at it without such selfish thought. If your parents filtered out that gene, they would have had the child without that gene. That's it.

  25. Re:I'll auto-Godwin myself by eugene+ts+wong · · Score: 4, Insightful

    Moderators, please mod him up as informative. Here is the take away paragraph.

    Early data suggests that a period of approximately two years of intermittent treatments may be required to attain the goal of long-term abstinence from narcotics and stimulants for many patients. The majority of patients treated with Ibogaine remain free from chemical dependence for a period of three to six months after a single dose. Approximately ten percent of patients treated with Ibogaine remain free of chemical dependence for two or more years from a single treatment and an equal percentage return to drug use within two weeks after treatment. Multiple administrations of Ibogaine over a period of time are generally more effective in extending periods of abstinence. It is noteworthy that twenty-nine of the thirty-five patients successfully treated with Ibogaine had numerous unsuccessful experiences with other treatment modalities.

  26. Re: about ibogaine, its not a panacea either by almechist · · Score: 3, Informative

    Moderators, please mod him up as informative. Here is the take away paragraph.

    Early data suggests that a period of approximately two years of intermittent treatments may be required to attain the goal of long-term abstinence from narcotics and stimulants for many patients. The majority of patients treated with Ibogaine remain free from chemical dependence for a period of three to six months after a single dose...

    Sorry, I do have points, but... No can do, on the upmod. If you spend some time on any of the sites that are genuinely run by and for addicts and ex-addicts, you will find many, many personal stories posted by sometimes desperate addicts who have actually tried ibogaine therapy. The basic message seems to be, no, it does not work, with actual results that are a far cry from the way the drug has sometimes been portrayed in the media and in the few very limited and suspect studies done to date. Ibogaine is in the same category as so-called "ultra-rapid detox" type treatments, which is to say that while it does have its true believers, the vast majority of those who actually undergo the treatment don't see anything remotely like the promised results. Most discover this to their chagrin only after spending huge amounts of money. The sad truth is, there is currently no overnight and/or one-time procedure that will cure addiction. Of course there isn't, it's an extremely complex and still imperfectly understood condition with causes deeply-rooted in both personality and brain chemistry. So like the mythical free lunch, there simply is no such thing as a miracle cure for addiction, and I don't see much hope there ever will be.