Bomb Blasts Alter Brain Lipid Levels
MTorrice writes "About 320,000 soldiers returning from the wars in Afghanistan and Iraq have struggled with neurological problems associated with traumatic brain injury, according to the Rand Corporation. Some veterans experience symptoms, such as memory loss and anxiety, without noticeable physical signs of brain injury. Now researchers report a possible chemical signature: Levels of a certain lipid spike in the brains of mice exposed to mild explosions (abstract; full article paywalled). This lipid could serve as a way to diagnose people who are at risk of developing neurological disorders after a blast, the scientists say."
The government says we should be able to live a content and productive life with only a partially functional brain.
But I imagine the researchers barely restraining their smirks after submitting a proposal to blow up mice as their study.
Wow !! Now I know to avoid bomb blasts !!
Maybe Jamie, Adam, Kari and Grant can donate their brains to science to see if they show the same markers. It would make a great series finale!
Maybe as a routine locker room procedure for impact and contact sports like football (either kind). It would beat the current "3rd concussion, you're in the injured reserve" regime, especially if it picks up sub-symptomatic TBI.
Welcome to the Panopticon. Used to be a prison, now it's your home.
Problem solved.
Now it's time for society to reap the what they have sown.
After all the drumbeats to war back in '02, people being called "Un-American" for saying, "Hold on a minute! Let's think about this before we go off!", we are now reaping what we have sown: trillions of dollars in of war debt pilled onto the other debt, a fucked up economy (wars are NEVER good for an economy - WWII included), people hating us even more which has decreased our security, and a class of combat veterans that are going to have issues for the rest of their lives - and all for what?
People who should be ashamed of themselves:
Donald Rumsfeld, George W .Bush, everyone on Talk Radio and Fox News, and everyone who voted Republican from 2001 - 2008.
It's your fault.
Given how vital lipids are to proper brain function(cellular function generally; but nerve tissue has tons of the things even by comparison to other tissues), it seems like a very ominous sign that blast trauma too minor to cause injuries visible even with an optical microscope causes noticeable changes in the lipids floating around... Even if the neural network isn't structurally disrupted at a visible scale, interference with lipids involved in chemical or electrical nerve signalling would still cause changes in how the network functions(since the characteristics of the paths are still changing, even if connections aren't being severed outright).
The brain is putting on weight (so to speak). What is being shorted as a result? Are synapses being pressured or is an important biological being substituted with lipids? Once diagnosed, confirming that they indeed suffered exposure to an explosion that, everyone knows occurred, what might be done to help? What is the cause, exterior or interior pressure, etc? If nothing is being done, or planned to be done, to help the afflicted, then the ongoing work is a waste of time.
one of the neatest recent developments in treating traumatic brain injuries is the finding that the human hormone progesterone dramatically improves the survival chances and outcomes of humans who sustain a traumatic brain injury. As someone who doesn't remember a 2-week period following a concussion/near drowning at the lake some 13 years ago, I wonder what my experience would have been like had my doctors known about this use for Progesterone USP.
Progesterone is the body's most important steroid hormone, because the body transforms it into the other steroids (cortisol, aldosterone, testosterone, estrogen) through the process of steroidogenesis. Birth control uses fake progesterone to help shut down women's hormonal cycling (and ovulation), which always results in progesterone deficiency (the chemicals in birth control do NOT fit into the steroid cycle).
Learn the rules so you know how to break them properly.
www.teslabox.com
If your so F'd up that you think going to War or even joining the military is a good idea then you deserve to have mental health problems set in. What the country wants to do is give you a number and tell you that your life is worth as much as gum on there shoe. They don't care if you die, if you get injured, if you live or even if you make your country look good. They want to use you as a means to an end and they really don't care. Take responsibility for your own life and tell your government to F off, If you really care about your life then don't join the military, go to school, get a job and really show what you can do when your not just a number.
lol from squity need shades to OMZG EYES WIDE OPEN RUN TYPE
lol
who does this shit no really what kinda value do i get
oh right im blown up good who cares then right
Anyone else read that headline as "bong blasts"? I really wasn't too surprised by the rest of it ....
People who should be ashamed of themselves: Donald Rumsfeld, George W .Bush, everyone on Talk Radio and Fox News, and everyone who voted Republican from 2001 - 2008. It's your fault.
Why not included Obama? How followed the Bush war plan. Surge in Afghanistan. Did *not* exit Iraq a single day earlier than Bush had planned and seems to be on the Bush schedule for Afghanistan as well.
I would think most people would suffer memory loss and anxiety (among many other concomitant symptoms) after experiencing round after round of painfully loud explosions, watching their buddies get blown apart and having to kill other human beings, simply due to the unbearably intense psychological strain. Looking at it as purely a physical matter seems to be missing the point a bit. Is physicality causing the mental stress, or is the causation the reverse?
I'm picturing mice dressed like Indiana Jones and James Bond running madly from a small toy boat loaded with black cats yelling in high pitched squeaks: "Get down! She's gonna blooowww!!"
"Molest me not with this pocket calculator stuff."
- Deep Thought
No, the paper doesn't say that. I checked. It's also not true; this can't be used for diagnosis (except maybe post-mortem), because it's on the wrong side of the skull.
...but damn it made me chuckle to think about spending my day in a lab "exposing rodents to minor explosions".
Hell, I pretty much did that research throughout the 6th grade. Amphibians as well.
-Styopa
They really should be affected by this, no? And you thought it was a cool job they had! ;)
The researchers are less likely to become attached to them and there are some things a mouse just won't do.
No brain, no pain.
So, PTSD may be half physical brain damage?
Seems like a bomb blast would alter the level of everything in the brain. Of course, those levels should stabilize within a few seconds, with final values determined by the heights of the surfaces they land on.
I wonder if benefits eligibility plays some role in such high rates of suffering from symptoms. I mean, either a "bad summary" or 320K is a very high number. Maybe researchers chasing ghosts.
"Notice the loss of hearing . . ."
I am not a crackpot.
I guess the ultimate neuro disease caused by a bomb is getting your brains blown right out of your head. Avoid bombs and avoid war. If you just have an absolute craving to mess with bombs it is best to be on the giving side of the equation at about 40,000 feet.
It also tells me that gunners who fire the big weapons surely must have biological harm from the percussion at firing. Imagine being a gunner on an old battleship and just how violent the inside of those gun turrets must have been. A few months of firing those guns might get you to the point of not minding if you survived or not.
Who would have thought!
The three laws of thermodynamics:(1) You can't win. (2) You can't break even. (3) You can't even quit.
One of the bizarre research results is that cooling of the brain after a concussion or explosion, can actually prevent most of this damage.
Various DARPA studies are underway.
"Sarge, Corporal Potter got an IED hit!"
"Pop an ice pack on his head and call the medic, Corporal".
-- Tigger warning: This post may contain tiggers! --
Why is this on /. instead of /r/politics?
Perhaps I'm missing something here but I thought blasts, particularly of the military kind, caused more than barely detectable chemical changes in some peoples' brains. Large craters, wrecked buildings and other things of a military significance come to mind.
This looks an awful lot like demonstrating just how sensitive testing procedures are. Reminds me of an interview I heard whereby the inventor of the then definitive test for determining if a substance is carcinogenic basically said that the test was so sensitive everything comes up as a bit carcinogenic. The thing is to determine what is size of "bit" truly significant.
Is it just bombs? What if firing guns at a gun range does it too?
Anxiety leads to depression which leads to anger which leads to violence.
Could it be possible that shooting guns recreationally messes up the biochemistry of peoples heads with any number of negative possible outcomes?
Need Mercedes parts ?
Now researchers report a possible chemical signature: Levels of a certain lipid spike in the brains of mice exposed to mild explosions
Maybe mild explosions like one experiences from the repeated firing of assualt style rifles inches from one's skull while using extend capacity clips?
TFA discusses traumatic brain injury (TBI), which reminded me of another FA that I read a while ago about detecting TBI with MRI machines.
Two guys, Dr. Walter Schneider and Dr. David Onkonwo, are using MRI to identify neural tracts throughout the brain. Their new technique, HDFT, is able to visualize the brain's wiring, and it can identify where the wiring has been broken.
http://www.cbsnews.com/8301-504763_162-57389325-10391704/new-technology-could-change-how-traumatic-brain-injuries-are-diagnosed/
:(){
So it has only taken 99 years to come up with an explanation for what was bleeding obvious since WWI. Shell shock is nothing new.
Respect for these guys who are dedicated professionals an put their lives on the line for what they think they believe. In the mean time, stupid, incompetent non-entities like Obama, Bush, etc sit back home and try to look good at the cost of the lives of these guys. I've been in similar circumstances, but being a young guy, you don't realise how much these socalled leaders are lying to you - you find that out way too late.
In the mean time, you're faffing about in other peoples' country where you've no business being, where you're not wanted (except by the greedy, stupid, incompetent non-entities who now see an opportunity to get into power at the cost of the lives of these soldiers). There are consequences. This is one of many. I know what I'm talking about.
drivers license.
purchase condoms
obtain a marriage license.
obtain a passport
obtain entrance to the no fly list.
and more ....
Truth is stranger than fiction, but it is because Fiction is obliged to stick to possibilities; Truth isn't. Mark Twain.
"So what you do you do for a living?"
"I explode mice."
*backs away slowly*
You'll find that the 'injury' they refer to is identical to mercury exposure in the brain. Ie, mercury casues it, plus all the symptoms. And for those that don't know, mercury is used as a preservative in the vaccines given to soldiers. So, it's inevitable that they'll all come away with stress, reduced immunity, mental disorders, a high TCell count, and so on and so on. The same company that markets the vaccines also tries to peddle the news that mercury is safe. Becuase they installed the same rubbish into kids vaccines, dental shots and tooth fillings.. However, they called the reactivity 'Autism'. So for those that want to yell Bullshit at the above story, take a look at who's actually causing the issue and who profits. Follow the money trail and it will all go back to the pharmaceutical industry trying to suck out as much cash as possible from govt's....