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Early Brain Response To Words Predictive For Autism

vinces99 writes "The pattern of brain responses to words in 2-year-old children with autism spectrum disorder predicted the youngsters' linguistic, cognitive and adaptive skills at ages 4 and 6, according to a new study from the University of Washington's Institute for Learning & Brain Sciences. The findings are among the first to demonstrate that a brain marker can predict future abilities in children with autism."

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  1. Still no editors at at Slashdot by Anonymous Coward · · Score: 5, Informative

    It's predictive OF cognitive ability FOR autistic children.

    1. Re:Still no editors at at Slashdot by Black+Parrot · · Score: 4, Funny

      Maybe the editors thought it was an article about dyslexia.

      --
      Sheesh, evil *and* a jerk. -- Jade
    2. Re:Still no editors at at Slashdot by Jane+Q.+Public · · Score: 2

      I don't buy this whole "autism spectrum disorder" thing in the new guidelines anyway. If you take their standards literally, then a very large percentage of people we would consider normal are actually autistic. Pardon me: suffering from "autism spectrum disorder".

      Sooner or later, if not checked, this ever-expanding list of "disorders" will eventually include literally everybody. When everybody has a "disorder", then who is normal?

      It's these BS "standards" that are unhealthy and need help.

    3. Re:Still no editors at at Slashdot by Jane+Q.+Public · · Score: 3, Insightful

      "Nobody is perfect, why shouldn't we categroize small errors as well?"

      Because it flies in the face of the very definition of "normal". Calling even the slightest deviation from some arbitrary norm a "disorder" is itself dysfunctional.

      We might as well label every vehicle that doesn't get exactly 50 mpg -- whether above or below -- "defective".

      Remember there was a time during which homosexuals were routinely sterilized or put in prison because they were not "normal". Hell, even heterosexual oral sex is STILL against the law in some states.

      Things like that are the reason why overly-narrowing the definition of "normal", and defining everything else to be a "disorder", is harmful.

    4. Re:Still no editors at at Slashdot by theedgeofoblivious · · Score: 4, Interesting

      As an autistic person, I think that "person first" language is offensive. Saying "person suffering from autism spectrum disorder" implies that autism is not a fundamental part of who I am, but is instead something inhuman that should be removed from me.

      No, person-first language is something that parents insist on. These are the same type of parents who post YouTube videos about "what autism is like", when in reality, they've never experienced autism, but instead have only experienced interaction with an autistic person. Autistic people don't suffer from autism. They suffer from other people.

      As for whether autism is real, it absolutely is.

      I am not a child. I exhibited the symptoms of autism long before the world wide web existed, so I didn't and my parents didn't get a fad diagnosis. We didn't know what it was. Everyone just thought that I was a genius, because of teaching myself to read and do math and memorize large amounts of information and fix things, but most people didn't realize that I had severe sensory issues and overwhelming social cognitive deficits. This is not just normal what people call "shyness" or social anxiety. Throughout my life I have had major issues because, far from trying to handle social situations and failing, there have been a lot of times when I didn't realize that I was supposed to interact, and there have been many types of social interaction that I didn't even have concepts of. When I was very young I was considered absolutely brilliant, but I also did a lot of things completely incorrectly. For example, I attended the wrong classes for a significant part of a school year because I never communicated that I was in the wrong classes, so none of the teachers realized it. I didn't understand that people formed networks with each other or attempted to socialize outside of school. I attended high school and college and never asked anyone for a reference, not because of fear, but because I didn't know that anyone did, and didn't have any concept of why they would.

    5. Re:Still no editors at at Slashdot by Samantha+Wright · · Score: 3, Informative

      Saying X is "a predictor for" Y is common statistics jargon. Just type "a predictor for" into Google and you'll drown in hits.

      --
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    6. Re:Still no editors at at Slashdot by king+neckbeard · · Score: 4, Insightful

      Actually, turning it from strictly binary to a spectrum is the road to a healthier approach, with the eventual destination being that they are not wrong, as 'disorder' implies, but merely different.

      --
      This is my signature. There are many like it, but this one is mine.
    7. Re:Still no editors at at Slashdot by Anonymous Coward · · Score: 2, Insightful

      I have to post as AC for this as I have used mod. points on this article so here goes. I to have "Autism Spectrum Disorder." I still prefer to say that I have Aspergers syndrome, and avoidant personality disorder due to the Aspergers. I was born in an era before the internet, and no one had a clue what autism was outside of the extreme cases. I did not form many friendships due to that issue, and when I did I got burned all the time because I was different and did not know social norms. I did ok in school until I hit high school and ONE teacher saw something in me. This lead to me being put in classes below my ability, which lead to boredom, which lead on to low grades. This process became a self-fulfilling prophecy until 10th grade when my english teacher saw that I was not being challenged enough. The rest of that year and all through the remainder of high school I was given more challenging classes and did well in them. I was 30 years old before I found out what was my issue. Thanks to a good friend of mine who is a nurse and recognized the signs of aspergers. Though this process took over a solid year for her to put the pieces together. During this time I was able to learn about the disorder and how to function in regular society; now almost no-one at work or outside of work knows that I have issues with social skills. I read another /. poster describing it as being in a foreign culture and not knowing what is going on, that is a very apt description of the condition. I have learned to "fake it till you make it" but I still have to stop and think of the right response to a situation. One of my immediate co-workers is also on the spectrum but he will never go see a psychiatrist, psychologist, nor therapist to work on his issues as he does not see anything wrong with him. He is the one person that I CANNOT work around for long as I see all of his flaws and want to correct them, but I know it will not work as he does not want to change.

    8. Re:Still no editors at at Slashdot by You're+All+Wrong · · Score: 3, Funny

      Is your final word an anagram/typo?

      --
      Your head of state is a corrupt weasel, I hope you're happy.
  2. Good News / Bad News by __aaltlg1547 · · Score: 2
    From the original article: The good news:

    “We’ve shown that the brain’s indicator of word learning in 2-year-olds already diagnosed with autism predicts their eventual skills on a broad set of cognitive and linguistic abilities and adaptive behaviors,” said lead author Patricia Kuhl, co-director of the University of Washington’s Institute for Learning & Brain Sciences.

    In other words, they can tell you a lot about your kid's future based on this one test.
    The bad news:

    “This is true four years after the initial test, and regardless of the type of autism treatment the children received,” she said.

    In other words, the autism treatments don't work.

    1. Re:Good News / Bad News by UnknownSoldier · · Score: 4, Funny

      >>âoeThis is true four years after the initial test, and regardless of the type of autism treatment the children received,â she said.
      > In other words, the autism treatments don't work.

      This is incorrect thinking. Autism is NOT something to be "cured."

      It is a DIFFERENT way of THINKING. See the movie "Temple Grandin" if you want to understand how Asperger's / Austistic children see the world.

      Didn't we just see something like this on /. recently?
      http://www.wired.com/opinion/2013/05/silicon-valley-coders-and-autism-and-asperbergers-maybe-its-a-new-kind-of-design-thinking/

    2. Re:Good News / Bad News by Anonymous Coward · · Score: 3, Insightful

      Fuck yourself. I have a nephew who will never lead an independent life because of autism and another who could live on his own but it would be a great difficulty for him and those around him. You or someone you know may have a form of autism that you find acceptable for every day life but everyone with autism isn't like that.
       
      You take a ton of offense at someone calling it a cure but you never consider what that cure might mean to others.

    3. Re:Good News / Bad News by F'Nok · · Score: 4, Insightful

      Which is pretty much what many adult autistics have been saying for quite a while now.

      Autism itself isn't something you can cure, nor would most autistics want you to attempt to do so.

      The current interventionist 'treatments' are all based on the idea that autistics lack something that non-autistics possess and that they can attempt to change that with treatment.

      The reality is that autistics are simply wired differently, and many things that are intuitive to non-autistics are difficult for autistics. Trying to teach such people to see the world the way non-autistics do is like trying to teach colour blind people to understand the nuances of colours. It's misguided and of course is ineffective because it ignores the actual fundamental differences in autistics.

      Most autistics can learn to navigate the non-autistic world and the social expectations of it, but that skill does not come from trying to change them, but by teaching them how they vary from others so they can appropriate respond to those others in a way they will understand, and communicate these differences where they matter.

      What this all fails to address however, is if people communicate with these children in an autistic friendly way, and teach them directly about how others vary from them, do the outcomes change? From (admittedly anecdotal) reports I've seen, it does.
      The only way to improve these outcomes is to throw out the idea that we can fix autistics and start to accept the idea that it's natural variation and as acceptance and understanding of this grows, negative outcomes will reduce.

      Disclaimer: I am an autistic adult, and I do not want or believe in any cures.

    4. Re:Good News / Bad News by Anonymous Coward · · Score: 2, Insightful

      I would very much agree with you. Being somewhat autistic myself, the best treatment to fit in was simply learning a bit more about the differences between autistic and non autistic people.
      Everybody needs to adapt behavior whenever they are with people different than themselves, you don't act the same around your bos as you do around your friends. The same is true for autistic people (exception being those that really can't work alone). We can adapt our behavior to better fit in with no autistic people, but we have to learn what the difference is between autistic and non autistic people, which for some possibly comes natural and for others does not.

    5. Re:Good News / Bad News by Anonymous Coward · · Score: 2, Insightful

      But it's still not really a 'cure', just like making someone who previously enjoyed sports dislike sports is not a 'cure'. Sure, some people may want the 'treatment', but to say that a person objectively needs to be cured because they think differently is just arrogant.

    6. Re:Good News / Bad News by Black+Parrot · · Score: 3, Insightful

      Autism itself isn't something you can cure, nor would most autistics want you to attempt to do so.

      In addition to the usual "I wouldn't be me anymore", I would add "I (literally) wouldn't know how to act - I've spent my whole life learning to adapt to the way I am".

      A year or two ago I asked a doctor whether there was any reason to even get it diagnosed in an adult, and his answer was that maybe it would help you get hooked up with a support group. As a (presumed) autistic adult, I found that to be a very strange notion... joining clubs isn't something that comes naturally for us, nor do most of us care to, once we've outgrown thinking we should try to be like everyone else.

      --
      Sheesh, evil *and* a jerk. -- Jade
    7. Re:Good News / Bad News by timeOday · · Score: 3, Informative

      "normal"? So failing to live the same way most people live is wrong?

      Oh please. People with severe autism are highly dependent on others for day-to-day care throughout their entires lives. (Of course the person above confused the whole issue by saying "Asperger's / Autism" as if we were just talking about being a bit geeky.) Here is what it is, not feel-good stories about mild cases.

    8. Re:Good News / Bad News by Anonymous Coward · · Score: 2, Insightful

      You are making the erroneous assumption that all autistic individuals are high functioning. This is not the case. Some people with autism need intensive interventions to simply function at a level where they can take care of themselves. High functioning individuals may also desire treatment in order to better integrate in society, but that is more a matter of choice since many of them can find their own place in society or develop coping mechanisms.

    9. Re:Good News / Bad News by Anonymous Coward · · Score: 5, Insightful

      Treatment for autism isn't a cure because nobody knows how to cure the disorder, but many people with autism certainly would like to be cured instead of painstakingly learning methods that help them mitigate the problems caused by their "different way of thinking". With all the hype around Asperger's Syndrome and other high functioning autism spectrum disorders, it's easy to forget that the few who despite their affliction manage to shine don't make the lives of the many easier.

      The antics of Sheldon Cooper are funny on TV, but if you take away the exceptional mental performance, then the social impediment causes real world Sheldon Coopers a lot of suffering, not because the world doesn't want to adapt to autism, but because social interactions are actually necessary and important. Unless you can bring that fabled "beautiful mind" stuff to the table, who's going to afford the time and stress to deal with someone who needs everything spelt out to them because facial cues and other normal aspects of social interaction are an enigma to them? Autism may in some rare cases enable new insights, but it comes at a cost, and that cost is crippling more often than not.

    10. Re:Good News / Bad News by F'Nok · · Score: 2

      You are making the deeply flawed assumption that just because I can communicate I must be 'high functioning'.

      Everything about functioning labels is wrong, it undervalues the functioning of people that can't communicate well, and under appreciates the functional challenges 'high functioning' people frequently have.
      There's a reason that these distinctions are removed from the DSM-5, because no matter how many times they tried, they actually couldn't find a consistent way to judge people as high or low functioning.

      In reality, functional labels seem to only get used to dismiss the opinion of those that can communicate:
      ie, "well you're not like those people that can't communicate, you're high functioning so you can't understand how they feel.
      The ironic undertone in that attitude is that the person saying it always makes the assumption that they must therefore understand the supposed low functioning people better.
      It's the most glaring example of paternalism in psychology that exists.

    11. Re:Good News / Bad News by Anonymous Coward · · Score: 2

      My son is an aspy - who is very, very bright. He is seeing an Occupational Therapist who had these wise words ... "the positive thing about your son's empathy is he doesn't give a shit about what anyone thinks about him". The conversation was around my son's "lack" of empathy.

      The only issue I have with his lack of empathy is his engagement of others. If he doesn't like you, he may just king-hit you if you annoy him ... regardless of how big you are. His much bigger brother has been the victim quite a few times.

      Note: this is not typical of all aspys. You have the fighters and the flighters.

    12. Re:Good News / Bad News by seebs · · Score: 2

      I've found that it's extremely useful just to have a word for it, because people are a lot less annoying about "I'd rather use email than phone, I'm autistic" than they are about "I'd rather use email than phone".

      --
      My blog: http://www.seebs.net/log/ --- My iPhone/iPad app: http://www.seebs.net/seebsfrac/
    13. Re:Good News / Bad News by Anonymous Coward · · Score: 5, Insightful

      Ugh, you've clearly never met someone with severe autism. The GP, who you nitwits have modded troll, has, and so have I. Some of them can't speak at all, nor can they understand speech. They can't understand tone of voice or facial expressions either. For them, it's as if they are trapped in a world of inscrutable aliens. They're easily overwhelmed by human interaction or even non-human stimuli, and react by going into a semi-catatonic state of rocking back and forth, or worse, by hitting themselves or bashing their head against a wall. They are completely incapable of leading anything resembling a normal life, and become a burden to their loved ones. They absolutely need a cure, and it is nothing like your frankly insulting sports analogy.

      But the internet is full of socially awkward young men who self-diagnose as high-functioning autistics. This lets them explain away their awkwardness while pretending they have super intelligence. And so, without ever having met one of the millions of people with severe autism (how could they, since those people normally don't leave their caretaker's home?), they declare that autism is a good thing and shouldn't be cured. Fuck every last one of those twits.

    14. Re:Good News / Bad News by Anonymous Coward · · Score: 3, Insightful

      No, no, no, NO, NO!

      This entire thread is fucking disgusting. You haven't met people with severe autism. I have. I've worked in a classroom for them. They have a severe and debilitating disability, which they can overcome through special education and extreme effort, both on their part, and on the part of their caretakers. Pretending that they're happy the way they are and we should just ... what? let them live their lives incapable of human interaction? ... is just sick.

      Would you say we should let the handicapped crawl, rather than teach them to use wheelchairs? Would you say we should let the blind stumble about, rather than teach them to use canes or seeing eye dogs? Then why the FUCK are you saying we should leave autistic people to their fate, rather than teach them how to cope with their disability? Because giving people the tools to survive in human society is paternalistic?

      This website gets worse every year. Bold, confidently-stated bullshit gets modded up over facts every time.

    15. Re:Good News / Bad News by Anonymous Coward · · Score: 5, Interesting

      I've seen the Temple Grandin movie, and it's spectacular. However, it is about a very high-functioning form of autism.

      My autistic cousin is not the high-functioning type. He can't speak, dress himself, or probably even use a toilet without assistance. He can't go out in public very often because he's prone to the kind of outbursts that would be excusable for a 2-year-old, but are likely to get a 30-year-old man like him arrested.

      His parents love him very much and are glad that they had him, regardless of his many challenges. However, he is an only child and they had him rather late in life. If won't be long before they're physically unable to care for him, or simply die. And what then?

      As a ward of the state, he will be much less useful to society than if he were "cured".

      What if we were talking about sociopaths? Would you say that it's just a different way of thinking that doesn't need to be cured? Perhaps you'd suggest that they have a useful place in society as politicians, completely ignoring the fact that some of them become serial killers (and that maybe society would be better off in general if we didn't have sociopathic leaders).

      dom

    16. Re:Good News / Bad News by ebno-10db · · Score: 2

      The people you are talking about usually have one of many severe debilitating conditions that are not autism in addition to being autistic, and yet people like you go around saying that their problem is they are autistic.

      You're trying to define away the idea that severe autism can be debilitating. Basically "if it's a fundamental problem, then it isn't part of autism". Yes autism, like almost everything else in DSM N, is very far from being well defined. However, by playing games with words and categories, you're making that worse. DSM N may suck, but one way to look at it is that it's a dictionary (yes, I know there are many ramifications beyond that). As such it provides a widely accepted definition for terms. By re-defining autism you add to the confusion. If you want to use your own term then make something up.

      There are many things where a certain amount just makes you different, but too much can be debilitating. For example, what's difference between being moody and being manic-depressive? Degree. Some would argue otherwise, but since the etiology is unknown, I think that's nonsense.

      Intellectual disability is not autism, but can happen in people that are autistic - there's likely an increased incidence as well.

      "Likely an increased incidence" is a vast understatement. Moreover the intellectual disabilities that severely autistic people display are often different in nature from those seen in non-autistic people. For example, people with autism usually have much greater difficulties with language than non-autistic but mentally disabled people who function at the same level on non-verbal tasks (alternatively you could say that the autistic people with the same degree of language difficulty perform much better at non-verbal tasks).

      Facilitated communication has been proving that non-verbal autistics can communicate perfectly well with non-verbal tools. Such as by typing!

      Some non-verbal autistics. There is a difference between verbal and language difficulties. For those who only have the former, typing is great. For the latter, not as much. There are also those in-between. For example, my nephew can speak and understand verbal language, but does better with written language. Unfortunately he's still far from communicating fluently even in writing.

      That you as a non-autistic know more about autism that I do, as an autistic.

      While probably not true of anyone on Slashdot, there are almost certainly people who know more about autism in a clinical and neurological sense than you do. What you know better than anyone who is not autistic is the experience of being autistic. Undoubtedly you've also learned a great deal about the other aspects. However, saying that you know more about it than non-autistics is like saying a tall person knows more about being tall than an endocrinologist.

    17. Re:Good News / Bad News by ebno-10db · · Score: 2

      You are making the deeply flawed assumption that just because I can communicate I must be 'high functioning'.

      It's not an assumption. Anyone who can communicate as well as you clearly is high functioning in at least one very important way. I would be thrilled if I could have a debate like this with my nephew.

  3. Re:It will be nice by fuzzyfuzzyfungus · · Score: 2

    I suspect that even a nigh-science-fiction breakthrough in robust biological characterization wouldn't free you of the dreaded 'spectrum'.

    Even among comparatively well understood and characterized medical problems, where you can run some labs or an MRI or something and get an nice graph and some numbers out, there are very few 'binary' disorders. You might either have a strep infection or not; but the only limit on the detail of the 'strep spectrum' is how much diagnostic detail is worth the effort. In principle, you could count up every last bacterium, rank the more heavily and less heavily colonized patients, classify them according to location(s) of heaviest infection, have subclasses based on efficacy of immune response(possibly even which elements of the immune response are active, and how fast they come online). If that isn't enough, you could even start looking at the (definitely variable from one person to another) genomes of the bacteria. Any special plasmids? Obviously, that isn't worth bothering with, because it'd cost a fucking fortune and(aside from a few basic tests for antibiotic resistance) wouldn't change the proposed treatment.

    The odds that a serious perturbation in something as complex as the human neural network wouldn't result in myriad different outcomes, of varying flavor and severity, seems vanishingly unlikely, even if you had arbitrarily good diagnostic tools at your disposal.

  4. Re:It will be nice by Black+Parrot · · Score: 2

    Autism is real. The "spectrum" is bullshit.

    Another A/C sets the adults straight.

    Perhaps 'spectrum' is merely a sign of our ignorance - maybe there are 29 different disorders that we call 'autism spectrum' due to our inability to distinguish them.

    OTOH, maybe its something you can have more or less of.

    And FYI, autism isn't the only disorder with a spectrum. Some have nothing to do with the brain.

    --
    Sheesh, evil *and* a jerk. -- Jade
  5. Re:Autism, to much hard work. by Black+Parrot · · Score: 2

    Soulless & emotionless. Don't protect the autistic - they need to be buried alive.

    As opposed to someone with emotion and soul, who would happily man the earth-mover. I understand that SS guards at concentration camps were particularly soulfull and emotional...

    If you want something to make you feel creepy, find the Wikipedia article about the concentration camp commandant executed by Poland after the war. At Nuremberg, when confronted with the charge of killing three million people, he corrected them by saying, no, he only killed two million - the rest died of disease or starvation. Shortly before his execution he said "people tell me I did something wrong".

    It's almost enough to make me believe in souls, because this guy was definitely missing something.

    --
    Sheesh, evil *and* a jerk. -- Jade