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Researchers Discover Another Layer To the Cornea

puddingebola writes with this excerpt: "A previously undetected layer in the cornea, the clear window at the front of the human eye, has been discovered by scientists at The University of Nottingham. This new layer, called the Dua's Layer after Professor Harminder Dua who discovered it, could help surgeons to dramatically improve outcomes for patients undergoing corneal grafts and transplants. This is a major discovery that will mean that ophthalmology textbooks will literally need to be re-written. Having identified this new and distinct layer deep in the tissue of the cornea, we can now exploit its presence to make operations much safer and simpler for patients," said Dua, Professor of Ophthalmology and Visual Sciences."

74 comments

  1. Publishers rejoice by CodeReign · · Score: 5, Funny

    Publishers rejoice as student are once again forced to purchase new books.

    1. Re:Publishers rejoice by Anonymous Coward · · Score: 1

      Oh please. Factual errors have never stopped a textbook from being used in class before.

    2. Re:Publishers rejoice by zoomshorts · · Score: 0

      Actually, hundreds of new books. Plus any errata that is generated in the rush to "catch-up".

    3. Re:Publishers rejoice by Mitchell314 · · Score: 1

      They do that on a regular basis anyways.

      --
      I read TFA and all I got was this lousy cookie
    4. Re:Publishers rejoice by houbou · · Score: 1

      well, thank god for the age of e-books! :)

    5. Re:Publishers rejoice by tlhIngan · · Score: 1

      Publishers rejoice as student are once again forced to purchase new books.

      Not just students, but every optometrist and ophthalmologist around as well.

      Basically it completely rewrites the textbook, so practically everything prior is now hopelessly obsolete.

      Including training courses and everything.

    6. Re:Publishers rejoice by K.+S.+Kyosuke · · Score: 1

      Publishers rejoice as student are once again forced to purchase new books.

      Of course.

      This is a major discovery that will mean that ophthalmology textbooks will literally need to be re-written

      If they had to be rewritten only metaphorically, they'd probably would be rejoicing much less.

      --
      Ezekiel 23:20
    7. Re:Publishers rejoice by blackraven14250 · · Score: 2

      Students already would have been purchasing new books, so publishers are probably ambivalent on this development.

    8. Re:Publishers rejoice by gtirloni · · Score: 1

      The trees are certainly happy about e-books. The students' pockets on the other hand... don't seem to be much affect since the industry wants to charge dead tree books' prices for e-books.

      --
      none
    9. Re:Publishers rejoice by Anonymous Coward · · Score: 0

      Oh please. Factual errors have never stopped a textbook from being used in class before.

      Yeah right. If the fucking textbook cover changes in color, they have a reason to force students to purchase the latest "supported" edition of the $250 book.

    10. Re:Publishers rejoice by K.+S.+Kyosuke · · Score: 4, Insightful

      When asked one unnamed major local publishing house about the translator rates, they told me that most of the costs go into printing and paper so they can't pay me much more than that. The same publishing house responded to public questions regarding cheaper e-books with telling the public that most of the costs are actually due to the editors, and chiefly due to the translator, so they can't sell the e-books at a significantly lower price because I'm too expensive. You're obviously a smart goy, do the math.

      --
      Ezekiel 23:20
    11. Re:Publishers rejoice by K.+S.+Kyosuke · · Score: 1

      That was supposed to be "smart guy". (I guess some typos are just embarrassin, but statistically, I guess I still have a 99.8 percent chance of being right with this only mildly stronger claim!)

      --
      Ezekiel 23:20
    12. Re:Publishers rejoice by Anonymous Coward · · Score: 1

      Actually, it's spelled "Schmott guy."

      http://girlgenius.wikia.com/wiki/Magnificent_Hat

  2. I know it is clear but.... by Anonymous Coward · · Score: 3, Funny

    How did this get missed for so long?

    1. Re:I know it is clear but.... by O-Deka-K · · Score: 5, Funny

      It was right in front of their eyes the whole time!

    2. Re:I know it is clear but.... by Anonymous Coward · · Score: 0

      It's 15 microns thick and just inside an already-known membrane.

    3. Re:I know it is clear but.... by Picass0 · · Score: 3, Funny

      It was staring them in the face!

    4. Re:I know it is clear but.... by gstoddart · · Score: 2

      I see what you did there. We'll have to wait until other people have a look at the data, we don't want to put a lid on it yet. Don' worry mon, evry'ting gonna be iris.

      --
      Lost at C:>. Found at C.
    5. Re:I know it is clear but.... by K.+S.+Kyosuke · · Score: 4, Funny

      I wish people stopped making these eyeronic remarks, it's not punny at all.

      --
      Ezekiel 23:20
    6. Re:I know it is clear but.... by Anonymous Coward · · Score: 0

      Cause it just evolved.

    7. Re:I know it is clear but.... by eth1 · · Score: 3, Funny

      Yes, but it wasn't right under their nose, so it's understandable they missed it.

    8. Re:I know it is clear but.... by steelfood · · Score: 1

      They had trouble seeing it.

      --
      "If a nation expects to be ignorant and free in a state of civilization, it expects what never was and never will be."
    9. Re:I know it is clear but.... by Anonymous Coward · · Score: 0

      Speak for yourself.

  3. Different Name by Anonymous Coward · · Score: 2, Funny

    I would have called it the "cornucopia"!

  4. And... by bfmorgan · · Score: 5, Funny

    "I see", said the blind man as he picked up his hammer and saw.

    --
    I hope this caused some synapses to fire.
    1. Re:And... by wonkey_monkey · · Score: 1

      "Now where do you want me to put these blinds?"

      --
      systemd is Roko's Basilisk.
    2. Re:And... by Richy_T · · Score: 2

      That joke is cornea.

  5. Wow.. but.. by houbou · · Score: 2

    so, this is all new.. which is great, but, then again, what about the procedures they have been doing for the last little while, say like Lazik for example? Wouldn't this little bit of knowledge be important prior to sending to the surgery? Is this going to affect those procedures?

    1. Re:Wow.. but.. by barista · · Score: 1

      It might be useful in developing new procedures or improving current ones, but it will take time. The new information isn't going to change anything drastically in the short term.

    2. Re:Wow.. but.. by Antipater · · Score: 1

      The "new" layer is between the stroma and Descemet's membrane (behind the stroma). Since LASIK and most other refractive procedures modify and reshape the stroma, they wouldn't even touch this layer. Corneal transplants, though, would be affected. A full-thickness transplant can take up to a year to recover from, since, among other reasons, there are no blood vessels in the cornea to aid healing. Partial-thickness transplants still take something like six weeks. Here's hoping this new knowledge can help speed those recovery times.

      --
      Everything is better with chainsaws.
  6. We've been looking right through it! by Anonymous Coward · · Score: 0

    How could they miss it!

    1. Re:We've been looking right through it! by RivenAleem · · Score: 1

      I think it's an issue of perspective.

  7. Axe by justthinkit · · Score: 0

    wouldn't "hammer and axe" make more sense? A saw can be guided to and then used to cut without the use of vision.

    --
    I come here for the love
    1. Re:Axe by Anonymous Coward · · Score: 0

      ...to his deaf son on the telephone.

    2. Re:Axe by CanHasDIY · · Score: 4, Funny

      wouldn't "hammer and axe" make more sense? A saw can be guided to and then used to cut without the use of vision.

      https://en.wikipedia.org/wiki/Word_play

      --
      An enigma, wrapped in a riddle, shrouded in bacon and cheese
    3. Re:Axe by Anonymous Coward · · Score: 0

      Whoosh! It's a pun, moron.

    4. Re:Axe by Nyder · · Score: 1

      wouldn't "hammer and axe" make more sense? A saw can be guided to and then used to cut without the use of vision.

      your response made me laugh.

      --
      Be seeing you...
    5. Re:Axe by chuckinator · · Score: 1

      WOOSH.

    6. Re:Axe by Archangel+Michael · · Score: 3, Funny

      Let me axe you a question.

      --
      Agent K: A *person* is smart. People are dumb, stupid, panicky animals, and you know it.
    7. Re:Axe by cellocgw · · Score: 1

      Let me axe you a question

      MIss Elizabeth Borden, is that you?

      --
      https://app.box.com/WitthoftResume Code: https://github.com/cellocgw
    8. Re:Axe by jfengel · · Score: 1

      The joke is often written as a "blind carpenter", which helps make the pun a bit tighter.

    9. Re:Axe by Anonymous Coward · · Score: 0

      It's a poetic pun.

    10. Re:Axe by Guignol · · Score: 1

      And this is why I keep coming here
      Thanx, that beats all the other whooshes by far !

    11. Re:Axe by riT-k0MA · · Score: 1

      Who said "what?" to his mute brother.

  8. This is one by maroberts · · Score: 2

    ..of the cornea-est stories on Slashdot.

    I'll get my coat...

    --

    Donte Alistair Anderson Roberts - hi son!
    Karma: Chameleon

    1. Re:This is one by telchine · · Score: 1

      This is one of the cornea-est stories on Slashdot.

      I'll get my coat...

      eye was waiting for someone to post a bad pun about this!

    2. Re:This is one by Richy_T · · Score: 2

      Good job we have a sense of vitreous humor.

  9. The eyes have it by Anonymous Coward · · Score: 5, Informative

    For those who don't bother to read TFA: Dua's layer is what keeps your eyeballs intact despite your eye being pressurized to a greater extent than the surrounding atmosphere. It can take up to two bars of pressure. The discovery helped doctors figure out what was behind the cause of several structural-weakness related illnesses of the eye and may lead to new treatment options for glaucoma sufferers.

    1. Re:The eyes have it by Anonymous Coward · · Score: 1

      This is very good news (besides providing grist for asinine comments). Anything that can help treat these 'orphan diseases' will be welcomed. My wife is 8 months into a cornea transplant after 30 years of living with severe keratoconus and for the last few years wearing 4 contact lenses (!). She had to have the procedure because her eyes couldn't deal with the contacts anymore and hard lenses are the main treatment for the disease. So far so good, but she's had some issues with living with 16 stitches in her eye for up to a year. In fall those come out and then the new cornea gets vision corrected (right now its 20/200). Then we're 'looking at' 2014 for the next eye. I am amazed at what can be done. Needless to say we'll also 'see' if her Dr. is aware of this development.

  10. Those corneas... by saturnianjourneyman · · Score: 1

    They're just like onions. Layers, layers, layers.

  11. Any doctors in the house? by gstoddart · · Score: 1

    Since I've never been to med school, and flunked out of biology because I couldn't stomach the dissections ... is this a really hard to find layer or something?

    I should think with all of the eyes which have been dissected by now, I can only assume this is a very hard to find structure if they're just finding it now. That or it looks like its part of another layer.

    Though, it just goes to remind us that modern science still doesn't know everything.

    --
    Lost at C:>. Found at C.
    1. Re:Any doctors in the house? by reverseengineer · · Score: 4, Informative

      From the experiments that were done to find this new layer, it seems that it is very difficult to separate from the adjoining layer (Descemet's membrane). Getting Dua's layer to separate from Descemet's membrane was a serendipitous result of simulating eye surgery (a lamellar keratoplasty, which is a partial corneal graft) involving the "big bubble technique," which uses an injection of air to separate Descemet's membrane from the corneal stroma. It turned out that it was sometimes possible to create this air bubble in specimens where Descemet's membrane had been removed, meaning there had to be another layer for air to get into. Otherwise, it wouldn't be easily detected as a separate layer.

      Here's what the "big bubble technique" looks like. It's pictures of eye surgery, so don't say you weren't properly warned.

      --
      "FDA staff reviewers expressed concern about the number of patients who were left out of the study because they died."
    2. Re:Any doctors in the house? by gstoddart · · Score: 1

      Thanks ... give or take a few points, that makes sense. But I think I'll pass on the pictures. ;-)

      --
      Lost at C:>. Found at C.
    3. Re:Any doctors in the house? by Anonymous Coward · · Score: 0

      Though, it just goes to remind us that modern science still doesn't know everything.

      Perhaps, but the real question is how much of modern science is being purposely hidden due to greed and corruption?

      Unfortunately, there is now too much money to be made in treatments, so even when cures are found, it's not likely to be made public. The Board wouldn't allow it.

    4. Re:Any doctors in the house? by Anonymous Coward · · Score: 0

      behind a paywall :/ I'll dare it and try google image search

    5. Re:Any doctors in the house? by DMUTPeregrine · · Score: 1

      Well, the cornea is very, very transparent. And all the layers are held together quite well, so finding a distinct layer likely is quite difficult.

      --
      Not a sentence!
  12. Please stop naming organs after people by Joshua+Fan · · Score: 0

    We don't need more organs with names that imply nothing about their function. Stop boosting the egos of these scientists, their goal should not be self-immortalization but advancement for the good of the scientific community.

    I thought we were transitioning away from those obscure, hard-to-remember names; such as the Eustachian tube in the ear getting renamed to simply auditory tube.

    1. Re:Please stop naming organs after people by Anonymous Coward · · Score: 0

      We have started to eliminate all people's names in anatomy. Why we would create new ones eludes me... I must say though that in cell biology, a lot of structures still possess the names of their discoverer's (Purkinje cells, Golgi apparatus, etc.)

    2. Re:Please stop naming organs after people by sjames · · Score: 1

      It makes perfect sense to use a person's name at first. Considering it's just been discovered, the jury is still out on what it does (if anything) it's a bit hard to name it based on function.

      If you think using names would be confusing, imagine a functional name 10 years later when we decide it doesn't do that at all.

    3. Re:Please stop naming organs after people by Anonymous Coward · · Score: 0

      Naming it after a person is more abstract, which can be helpful our knowledge of something's function is still evolving or it turns out to be multifunctional. You could always change the name down the line if the function becomes better understood, but then when doing old literature searches, you would now need to search for two things.

    4. Re:Please stop naming organs after people by Anonymous Coward · · Score: 0

      We don't need more organs with names that imply nothing about their function. Stop boosting the egos of these scientists, their goal should not be self-immortalization but advancement for the good of the scientific community...

      ...says the uber-nerd who still names his servers after Star Wars planets and characters.

      For a minute there I thought "Wookie" was the email server, not the DNS server. I mean, what the fuck was I thinking...

    5. Re:Please stop naming organs after people by Joshua+Fan · · Score: 1

      What the bejeezus are you talking about?

    6. Re:Please stop naming organs after people by egnx · · Score: 1

      Meh. Prof Dua and Dr Mengeler have given my wife the ability to see for the past 15years, if he gets a layer named after him then thats just fine by me. Thanks Prof. on behalf of all your patients.

  13. Textbooks rewritten? by Anonymous Coward · · Score: 0

    More like one paragraph in a 2000 page book....

    Every one tries to glorify their accomplishments. These are called new n00b attention seeking scientists.

  14. Just below ... by PPH · · Score: 2

    ... the second eyelid that blinks sideways.

    --
    Have gnu, will travel.
    1. Re:Just below ... by TeknoHog · · Score: 1
      --
      Escher was the first MC and Giger invented the HR department.
  15. Good news for us losing vision by Gothmolly · · Score: 1

    As someone who is losing vision due to a degenerative corneal condition, this is good news. Maybe soon they can pop them out, give them a tuneup, and put them back in.

    --
    I want to delete my account but Slashdot doesn't allow it.
  16. Cornea is in the eye of the beholder! by Anonymous Coward · · Score: 0

    There, now I've said it.

  17. We are obviously Related To by keithltaylor · · Score: 1

    the Vulcans. Like the inner eyelid Spock realizes he has in TOS: "Operation -- Annihilate!" Meant to protect us in the days we had 2 suns before one went nova. I made that last part up.

  18. I knew it! by Tablizer · · Score: 2

    It's transparent turtles all the way down

  19. Dua's Layer by ThatsNotPudding · · Score: 1

    I assume the NonEgotistical Layer name was taken.

    I wonder how many cool nicknames he's also given himself.

    1. Re:Dua's Layer by Anonymous Coward · · Score: 0

      You must get really depressed reading an anatomy textbook then. Just about every small feature of your body has a doctor's name who discovered what it was for -- Cowper's glands, islets of Langerhans, Broca's area, and these are just the tip of the iceberg.

  20. It's called... by Anonymous Coward · · Score: 0

    ...Google Glass.