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Nanoparticle Exposure Could Disrupt Immune Cell Function

MTorrice writes "A new study suggests there's more to nanoparticle toxicology than cell life and death. Although immune cells treated with iron oxide particles appeared healthy in standard toxicology tests, they struggled to perform one of their key jobs: engulfing pathogenic bacteria. The researchers wonder if exposure to significant levels of the nanoparticles could lead to dysfunction in people's immune systems."

16 of 31 comments (clear)

  1. Turn that around by Spy+Handler · · Score: 4, Interesting

    researchers should wonder if exposure to nanoparticles will disrupt cancer cell function or antibiotic-resistant superbug function and devise a strategy to shoot them with the appropriate nanoparticles.

    1. Re:Turn that around by Rhywden · · Score: 1

      I wonder if you actually spent two seconds thinking about this our simply spouted off another tangent for your favourite conspiracy theory.

      Seriously, if it were nano particles it wouldn't explain why:
      - it's a sexually transmitted disease (through exposure to blood)
      - it has a variable dormancy period
      - why it gets more serious with time passing (nanoparticles would, just like heavy metals, eventually leave the body)
      - why it's treatable with antiviral medicine.

    2. Re:Turn that around by Anonymous Coward · · Score: 1

      yes

      http://www.ncbi.nlm.nih.gov/pubmed/?term=nanoparticles+cancer

      and yes

      http://www.ncbi.nlm.nih.gov/pubmed/?term=nanoparticles+bacteria

    3. Re:Turn that around by Anonymous Coward · · Score: 1

      A study was just released describing a potential link between MS (an immune disorder) and Iron deposits
      http://www.thealmagest.com/2013/07/gray-matter-damage-linked-to-multiple-sclerosis/

    4. Re:Turn that around by buswolley · · Score: 1
      --

      A Good Troll is better than a Bad Human.

  2. Finally, somebody understands. by Anonymous Coward · · Score: 1

    Nanoparticles that are the size of mineral molecules will displace the essential minerals from their place in the enzymes that make up the function of the immune system. This is the same problem with heavy metals. The implication is we will probably never be able to successfuly manipulate the body's immune system to any significant degree. Anybody who tells you otherwise is trying to sell you the Brooklyn Bridge.

    If you want to cure degenerative illness, then take out heavy metals and don't poison yourself with chemicals. This is a good as it gets.

    1. Re: Finally, somebody understands. by Gilmoure · · Score: 2

      Exactly! As things stand now, that's as good as it'll ever be. Human beings are not exactly known for making advances in areas where everyone knows advances can't be made.

      --
      I drank what? -- Socrates
    2. Re:Finally, somebody understands. by wonkey_monkey · · Score: 1

      don't poison yourself with chemicals.

      Damn straight. From now on I'm not letting any chemicals into my body!

      --
      systemd is Roko's Basilisk.
    3. Re:Finally, somebody understands. by bdwebb · · Score: 2

      Hmm...you lost me when you said we won't be able to successfully manipulate the body's immune system...what about vaccines? That is pretty effective manipulation, sans-bridge.

  3. Microaids by dadelbunts · · Score: 1

    From the makers of superaids. Now in an easier to swallow form.

  4. Remember that many nanoparticles occur naturally by Ambassador+Kosh · · Score: 1

    It is great that we are learning this stuff. However nanoparticles are not in general good or bad, they are an entire class of molecules that are on the scale of a nanometer. Some will be good, some will be bad and the more we can learn about this the better off we are. There are some we have found that tend to concentrate in certain cell types and may help or harm the cell depending on what they are.

    This is an area that needs a massive amount of effort and research. I suspect that many of the illnesses that people have now are actually caused by naturally occurring nanoparticles and that the cures for them is likely to be found in other types of nanoparticles.

    --
    Computer modeling for biotech drug manufacturing is HARD! :)
  5. in other news by stenvar · · Score: 1

    Exposure to liquids can cause poisoning, and exposure to solids can cause bullet wounds. We should avoid all liquids and solids, just to be sure.

  6. Pills by Misagon · · Score: 1

    Yet, practically all types of medicinal pills still contain nanoparticles of Titanium Dioxide, used only for colouring the pills white.
    It is not like you have the option of choosing another brand that does not have nanoparticles. Often the prescribed medicine is the only one available with the active ingredient ... or all the brands contain TiO2.
    TiO2 is also in many brands of sunscreen, but in this case it is much easier to choose another brand.

    --
    "We mustn't be caught by surprise by our own advancing technology" -- Aldous Huxley
  7. Re:BAN IT ALL NOW by Anonymous Coward · · Score: 1

    Thats just it, we don't "adopt reasonable precautions as we do for any other hazardous substance". You wonder why our country is plaged by chemically induced illnesses? Because congress made it legal to do so in 1976.

    Lookup the Toxic Substances Control Act of 1976. A complete travesty. Congress sold your health and pocketed the money and kissed babies after they kissed Monsanto's ass.

    Now you know why cancer won't be cured any time soon.

    This is just as good a reason to riot than anything else I've seen recently.

  8. No Need by caspy7 · · Score: 1

    No need to turn it around, we can have both.
    But if it turns out the cure is worse than the cause, these are good questions to answer.

  9. Miracle Material by ThatsNotPudding · · Score: 1

    Once upon a time, asbestos was considered a miracle too.

    Material that can effortlessly pass thru the blood / brain barrier are being used in more and more products with no foresight whatsoever (commerce!). This will not end well.