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Sleep Found To Replenish a Type of Brain Cell

New submitter wrackspurt writes "Sleep deprivation has long been thought to be prevalent in the industrialized world. A new study (abstract) explains one very good reason why at least seven hours of sleep a night is necessary. Quoting the BBC: 'Sleep ramps up the production of cells that go on to make an insulating material known as myelin which protects our brain's circuitry. ... The increase was most marked during the type of sleep that is associated with dreaming - REM or rapid eye movement sleep — and was driven by genes. In contrast, the genes involved in cell death and stress responses were turned on when the mice were forced to stay awake.'"

38 of 136 comments (clear)

  1. I know that I need mine by ModernGeek · · Score: 3, Funny

    If I don't get an ample amount of sleep at night, I am absolutely useless for any sort of skilled work.

    --
    Sig: I stole this sig.
    1. Re:I know that I need mine by jellomizer · · Score: 5, Interesting

      1 Hour, Things after a few hours start to move funny
      2 Hours, I go for an hour or so, then I doze in and out for the rest of the day
      3 Hours, I go a few hours, and blink out for a few minutes every half an hour
      4 Hours, I can get threw the day, but I can't do much
      5 Hours, I am am at reduced functionally
      6 Hours, I can function during the day, but I am tired.
      7 Hours, I am fine, however I am kinda grumpy
      8 Hours, No problems
      9 Hours, A lot of sleep and a LOT of energy
      10 Hours, Too much sleep and I am kinda groggy
      11 Hours of sleep I get Grumpy again
      12 Hour a sleep I wander around like a zombie I spend the day like I just woke up.

      --
      If something is so important that you feel the need to post it on the internet... It probably isn't that important.
    2. Re:I know that I need mine by Antipater · · Score: 5, Funny

      4 Hours, I can get threw the day, but I can't do much
      5 Hours, I am am at reduced functionally

      Only got 5 hours last night, eh?

      --
      Everything is better with chainsaws.
    3. Re:I know that I need mine by ackthpt · · Score: 2

      If I don't get an ample amount of sleep at night, I am absolutely useless for any sort of skilled work.

      The tireder I gets the more me grammer suffers.

      --

      A feeling of having made the same mistake before: Deja Foobar
    4. Re:I know that I need mine by Anonymous Coward · · Score: 3, Funny

      Protip: Manning the fryer at McDonalds is not skilled work.

      Its close to being skillet work though.

    5. Re:I know that I need mine by X0563511 · · Score: 3, Insightful

      I think we'd all be amused watching you try.

      --
      For large sets, this will be our guide even unto death, for the LORD will work for each type of data it is applied to...
    6. Re:I know that I need mine by PopeRatzo · · Score: 5, Interesting

      Does anyone else have an above-average sleep requirement?

      I used to think I needed more sleep than average. But once I put a little thought into my sleep patterns and methods, I learned a real lesson about it. My wife and I spent a little money on a really good mattress (OK, it wasn't so little) and really good pillows (You ought to try MyPillow). Then, on a lark I tried using an Android app on my Nexus 7 called "Sleep as Android", which tracked my movement as I slept and tried to wake me when my sleep was the shallowest. Then, it graphs out your sleep patters (when you're sleeping deeply and not moving and when you're restless or snoring or tossing and turning). Finally, when you wake up you rate how you feel on a scale of 1 to 5 stars. After the few months, I was surprised to find that when I sleep between 7:15hrs and 7:30hrs I felt best and had the best, most productive days. Occasionally, I would try to sleep 8 or more hours and I'd never feel as well or work as well.

      So now, I sleep almost exactly 7:15hr to 7:30hr every night. I wake up without an alarm and fall asleep quickly and have great dreams. (the app has some "lucid dreaming" features that will play a little sound when you get into the deepest sleep state, and that got me in the habit of lucid dreaming - during which I'm almost always playing music, for some reason).

      It's worth taking an informed approach to sleep instead of just assuming "I need 9 hours". We sleep such a large percentage of our lives, and most of us really don't give much thought to it.

      --
      You are welcome on my lawn.
    7. Re:I know that I need mine by sporkbender · · Score: 2

      I found that I am the same way, I need 8 hours, but only get 4-6 because I cannot fall asleep (I take a sleep aid and melatonin has never helped). Go to the doctor, I finally did and found it is more than stress....I have a hyperactive thyroid.

    8. Re:I know that I need mine by TemperedAlchemist · · Score: 4, Insightful

      That's about spot on. You falling asleep quicker would account for the discrepancies, it takes most people thirty minutes to fall asleep.

      When it's said that you should get eight hours of sleep per night, what's actually meant is that you should get eight hours of uninterrupted sleep in a dark, silent, and comfortable room on a consistent and precise schedule.

      Naturally there's more to sleep than simply duration. A lot more, in fact.

      ---

      I envy people like you. For some reason fate has decided to curse me to severe insomnia, and I require sleeping pills to maintain anything remotely normal.

    9. Re:I know that I need mine by ackthpt · · Score: 2

      When I was a wee young coder in college I pulled an all-nighter on a coding project. Big ol' statistical engine. Somewhere around 3 AM the code took on a narrative form ... I went off to the dorm for a couple hours sleep and came back to look at it ... whaaaa??? It looked perfectly fine to an exhausted brain. Perception clearly suffers from sleep deprivation.

      --

      A feeling of having made the same mistake before: Deja Foobar
    10. Re:I know that I need mine by Anonymous Coward · · Score: 2, Insightful

      It's worth taking an informed approach to sleep instead of just assuming "I need 9 hours". We sleep such a large percentage of our lives, and most of us really don't give much thought to it.

      So you changed multiple factors. Great. Now we have no idea what to do. Was it the better mattress or the Android app? Or was it the pillow?

      You've changed too many things to gather any useful information about your sleep.

    11. Re:I know that I need mine by NewtonsLaw · · Score: 2

      You guys are all sissies! :-)

      The longest I've gone without sleep is almost 48 hours and I have to say the last few hours of that were really trippy!

      I was working hard to get a big software project out the door and I have to say that I was pretty productive right up to about hour 40 -- then I started making mistakes (despite the coffee). By about the 44th hour I was decidedly paranoid so decided to walk home and have some sleep.

      That walk home was so damned scary. The sun was just coming up and it felt like there were people hiding behind every lamp-post and in every shadow.

      Once I did get home and fall into bed, I could not get to sleep for several hours because I was constantly getting up to check if the door was locked and to check every little noise.

      It's an experience that everyone should have at least once (so they can understand it) but hell, I'd never do it again.

      When I was younger I could pull the occasional overnight coding session (24hrs straight) and recover with just 4-5 hours of sleep but these days (I'm 60 now), even missing an hour's sleep makes me feel crappy the following day.

      What's always annoyed me most about sleep deprivation is that you feel crappy -- right up until the mid/late evening of the next day when it's time to go to bed. Suddenly, the feelings of fatigue subside and you're tempted to stay up even later than you did the night before. They say most people's circadian cycle is closer to 25 hours than 24 hours and in my case I know that is true.

      I was once working in an isolated location (more productive coding that way) and simply went to bed when tired -- got up when I awoke. Sure enough, my sleep period slowly drifted around -- getting about an hour later every day until over the period of nearly a month, I was right back where I started.

      Sleep is interesting stuff -- it's just a shame I'm never awake when it happens :-)

    12. Re:I know that I need mine by Maxo-Texas · · Score: 2

      Now put that in terms of how many days in a row you've done it.

      My sleep pattern used to be 12,6,6,7,6,6,7 due to everquest.

      The 12 was involuntary.

      Sometime it was 15-18.

      --
      She was like chocolate when she drank... semi-sweet at first and then increasingly bitter.
  2. What? by Toe,+The · · Score: 4, Funny

    I don't understand this article. Couldn't sleep last night.

  3. Myelin by cookYourDog · · Score: 2

    May provide for insights into research on multiple sclerosis, a disease in which the body attacks its own myelin sheaths around nerves.

  4. Re:Where? by Anonymous Coward · · Score: 4, Funny

    In your dreams, uberbrainchild, in your dreams!

  5. Re:Where? by sdoca · · Score: 2
  6. Linus Torvalds on sleep by Anonymous Coward · · Score: 4, Interesting

    "A lot of people believe in working long days and doing double,triple, or even quadruple shifts. I’m not one of them. Neither Transmeta nor Linux has ever gotten in the way of a good night’s sleep. In fact, if you want to know the honest truth, I’m a firm believer in sleep. Some people think that’s just being lazy, but I want to throw my pillow at them. I have a perfectly valid excuse, and I’m standing by it: You may lose a few hours of your productive daytime if you sleep, oh, say, ten hours a day, but those few hours when you are awake, you are alert and your brain functions on all six cylinders. Or four or whatever."

    from "Just for Fun: The Story of an Accidental Revolutionary" by Linus Torvalds and David Diamond

  7. Engineering the Brain by mfwitten · · Score: 3, Insightful

    Is it possible that controlled sleep deprivation could result in the culling of strictly unnecessary brain cells, so that the overall result is a more power-efficient brain? The first time I pulled an all-nighter to work on mentally taxing problems, I had to sleep 19 hours to recover. After doing that kind of work regularly, only a few hours or recovery became necessary.

    1. Re:Engineering the Brain by Minwee · · Score: 5, Funny

      Let's just say that you don't notice the problem as much as you used to.

  8. Re:I think its safe to say by gstoddart · · Score: 5, Interesting

    Well, it's one thing to say lack of sleep makes you sleepy and ineffective.

    To me it sounds like something else entirely to say the myelin isn't getting replenished -- especially since myelin breakdown has been linked with Alzheimer's and dementia.

    So (based on my complete lack of attending med school) ... doesn't this potentially make more longer term problems in the brain?

    My read on this is this has much broader implications than how you're going to be ineffective the next day. As in, in the long run, your brain may simply be degrading more than it can keep up with than if you'd had enough sleep over that time.

    Next time the wife complains when I go take a nap, I'll remind her that I'm re-building my myelin and I need to do that so I don't get any dumber. :-P

    --
    Lost at C:>. Found at C.
  9. Re:Where? by Minwee · · Score: 4, Funny

    From delicious, tasty brains.

  10. apnea by nblender · · Score: 4, Informative

    I'd been living with sleep apnea for years, but didn't realize it. I just thought that getting up to pee 3 or 4 times in a night was normal for a 42 year old... Turns out it's not. It was my body's way of trying to figure out why it was awake and concluding it must be because my bladder was full. I did a sleep study and found that I would stop breathing 260 times in the first 3 hours of sleep after which time I started waking up and that was the end of the study... I was fitted with a sleep apnea dental appliance (the TAP3 device) and the first night I slept through the entire night for the first time in years... My wife kept waking up to make sure I was still breathing because I wasn't snoring or making any noise at all. After some adjustment, I can say I sleep like a baby now... I spent a lot of money on matresses and pillows before, thinking it was the bed's fault...

    The way the dental appliance works is by extending your lower jaw (as though you have a terrible underbite) which opens up your airway.

    Very occasionally, I will forget it when I go somewhere for an overnight, and I sleep like shit those nights... I wake up multiple times, have a sore throat in the morning (from snoring loudly), have no energy, and no motivation.

    I've had it for 2.5 years now and can't imagine life without it. I also can't imagine life with a CPAP machine though I hear they work great for some people.

    1. Re:apnea by Daniel+Dvorkin · · Score: 3, Funny

      After some adjustment, I can say I sleep like a baby now

      You wake up every few hours screaming because you need your diaper changed?

      --
      The correlation between ignorance of statistics and using "correlation is not causation" as an argument is close to 1.
    2. Re:apnea by Bigbutt · · Score: 3, Funny

      Nah, I wake up every couple of hours needing to be fed. Now where is that breast?? :D

      [John]

      --
      Shit better not happen!
  11. But I already knew this. I always knew this. by Narcocide · · Score: 2

    I could feel it killing me, when I was forced to wake up too early as a child. I could feel it stretching my consciousness thin... the most appropriate description for the feeling is the one used by Bilbo Baggins; "... like butter scraped over too much bread."

    I predict that next they will discover that while 7 may be an absolute minimum for basic health, some people will need more depending on their brain capacity and "usage patterns." I predict they will eventually discover that having at least 8 hours every night during childhood will prevent the onset of Alzheimer's disease in old age. I further predict that never going under-slept (sleeping in up to even 10+ hours if necessary to stop feeling groggy or "stretched") will eventually prove to extend longevity by 20-50% and cure a whole host of neuroses and other emotional and psychological disorders.

  12. Re:Back in teh 80's by GameboyRMH · · Score: 2

    And which hair metal band were you a part of?

    --
    "When information is power, privacy is freedom" - Jah-Wren Ryel
  13. Re:Back in teh 80's by Joce640k · · Score: 2

    Back in the 80's, I constantly heard "You'll sleep enough when you're dead." or "Sleep is for wimps."

    It was a trap! They wanted you at your worst.

    --
    No sig today...
  14. Re:Why does too much sleep make you groggy? by Narcocide · · Score: 3, Insightful

    Because 16 hours is a long time to go without food, even if you are asleep the whole time. You need to strike an appropriate balance between rest and nutrition and activity. We have lost our natural rhythm.

  15. Re:Where? by idontgno · · Score: 2

    Oh.

    Zombies aren't shambling horrors mocking life with their undeath. They're just REALLY sleep-deprived.

    Makes perfect sense. I turn into a zombie after 22 continuous hours without sleep, so that must be what's happening.

    --
    Welcome to the Panopticon. Used to be a prison, now it's your home.
  16. I got something good from it. by Valdrax · · Score: 4, Insightful

    We have enough studies telling you not to do this particular thing where you feel like complete and utter crap if you do.

    Well, cool. You must feel pretty proud about learning absolutely nothing from this study except how your preconceived notions (aka "common sense") were correct to brag about it here and bash the authors for their useless work, but personally, I was fascinated by the info about sleep mediating gene activation and its effects on myelin growth.

    Providing a mechanism to explain why you feel like utter crap is important -- especially for people who just like to soldier through chronic sleep deprivation and say they can handle it. Turns out, no, you can't -- you're literally killing your brain slowly, and that candle you're burning will run out much quicker. I've been trying to get myself into bed earlier each night, and I've heard studies that tell me that I'm shortening my life by not getting enough sleep, but now I know how and why and that I may be doing long-term brain damage by not fixing that problem, and that provides extra impetus to stop coasting and solve it right now.

    This article, in the long run, may save my life (or at least greatly extend it) by giving the final kick in the pants to do something solid about it. (Especially since I'm half-dead today from lack of sleep.)

    --
    If it's for-profit but free, you're not the customer -- you're the product (e.g., the Slashdot Beta's "audience").
    1. Re:I got something good from it. by b4upoo · · Score: 3, Insightful

      It also makes a point that our government may not like. Forced sleep deprivation which has been a form of torture of prisoners meets any definition of torture as it causes a brain injury that is permanent. Bradly Manning was constantly awakened for meaningless searches while in isolation. Even in situations such as the Branch Davidian incident the use of loud, obnoxious music was used to try to disrupt the lives of the occupants.

  17. why do I have the notion by Mister+Liberty · · Score: 2

    ...that all of this is old news?

  18. Re:What if? by Narcocide · · Score: 2

    Other things will go wrong instead; its not just cellular structure that is replenished during sleep but critical fluid chemical balances as well.

    Luckily for you though, the United States military already has a drug to manually re-balance those other chemicals. It has been tested extensively for years and has been reported to keep your reaction times and accuracy levels to within well-rested parameters for up to 40 hours without any of the side effects of amphetamines traditionally used for such exercises.

  19. Sleep Hygiene by wrackspurt · · Score: 2

    Dr. W.C. Dementbooks are a good place to start if your interested in an overview of the importance of sleep. Sleep hygiene is probably the idea currently being pushed to the forefront. The idea that a good night's sleep is as much a part of overall health as other good hygiene practices.

  20. Re:But I already knew this. I always knew this. by Narcocide · · Score: 2

    Note: being a parent doesn't make you automatically right, or even more informed about basic health in any way whatsoever. Convenience to you doesn't automatically make it healthy for the kids either.

  21. Re:I think its safe to say by avandesande · · Score: 2

    Look into melatonin to increase your REM sleep.

    --
    love is just extroverted narcissism
  22. Re:I think its safe to say by TemperedAlchemist · · Score: 2

    If you're not interested in the basic research, at least be interested that this is the groundwork for potentially eventually curing humans of sleep entirely.