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FDA Seeks Tougher Rules For Antibacterial Soaps

barlevg writes "It's long been a concern that the widespread use of antibacterial soaps is contributing towards the evolution of drug-resistant 'superbugs,' but as the Washington Post reports, the Food and Drug Administration also does not believe that there is any evidence to support that the antibacterial agents in soaps are any more effective at killing germs than simply washing with soap and water. Under the terms of a proposal under consideration, the FDA will require that manufacturers making such claims will have to show proof. If they fail to do so, they will be required to change their marketing or even stop selling the products altogether."

15 of 160 comments (clear)

  1. Come on by therealkevinkretz · · Score: 5, Insightful

    The bigger problem is antibiotic use on farms, and the FDA's recent toothless rules ( http://theweek.com/article/index/254057/why-the-fdas-new-antibiotic-rules-fall-short ) rely on the farmers who use them to mediate the results of cruel conditions (overcrowding, etc) and the companies who sell them to voluntarily cut back on their use. Good luck with that.

    Meantime they hit hard on Purell users. Bah.

    1. Re:Come on by sribe · · Score: 4, Informative

      The antibacterial in most hand sanitizers [wikipedia.org] is simply alcohol.

      Yes, but hand sanitizers are not the subject of the article. "Antibacterial soaps" are, which is an entirely different subject.

    2. Re:Come on by MillionthMonkey · · Score: 4, Interesting

      The U.S. FDA differs from the corresponding agencies in other First World countries because it has a different standard for determining safety. Usually, a manufacturer has to prove a new chemical is safe before they can put it on the market. In the U.S., the standard is different. Unless a third party can prove to their satisfaction that the product is unsafe, the manufacturer can continue to sell it. This is why bisphenol-A, for example, is used in the lining of all canned foods in the U.S. and not in other countries. Although studies have repeatedly come out indicating that it binds to estrogen receptors and mimics estrogen in some ways, the FDA has claimed that no one study in humans has conclusively proven that BPA has effects. BPA studies are difficult in humans because it's impossible to shield a control group from exposure to it- virtually all foods sold in the U.S. are laced with it, with no labeling requirements whatsoever. China has banned the use of BPA, but still manufactures millions of tons for exports to the U.S.

    3. Re:Come on by blueg3 · · Score: 4, Insightful

      Yes, the first point is entirely true: widespread use on farms is where one of the major problems are.

      Home-use soaps are potentially a concern, but a much smaller factor.

      Your confusion is appropriate: the marketing of things as "antibacterial" is inconsistent and, mostly, stupid. There are soaps (and other consumer products, like plastics) that include a wide variety of different antibiotics, ones that include different kinds of bacteriacides altogether, and ones that include simple things like bleach and ethanol. Purell, which is ethanol, is certainly antibacterial, in that it's excellent at killing bacteria. But in this article, when they're talking about "antibacterial soaps", that's not what they mean. So consistent and helpful!

  2. there is proof by iggymanz · · Score: 5, Informative

    the "anti-bacterial" ingredients are chlorinated organics, they just poison bacteria. they are not in any way related to antibiotics and thus do not in any way conribute to resistance to antibiotics any more than your chlorinated kitchen cleanser does. Trivial to prove soaps with them they kill bacteria, that's already been done. they are even used to kill resistant bacterias on skin in certain medical protocols, look it up.

    I'm allergic to one of the chemical, so I won't be crying if they are banned. but the "tin foil hat" health sites make absurd claims about their contributing to the breeding of super bugs

    1. Re:there is proof by barlevg · · Score: 4, Insightful

      The issue is not whether they kill germs. Hell, "old age" will eventually kill bacteria. The issue is whether antibacterial soaps are any more effective than just soap and water.

    2. Re:there is proof by emorning9707 · · Score: 5, Informative

      It is a given that soap kills bacteria.

      Soap doesn't kill bacteria, it merely dissolves the oil that enables the bacteria to cling to your skin, thus allowing water to flush them away.
      Soap and water is so effective at removing bacteria that adding a microbial agent to the soap has no benefit, because there are so few bacteria left on your skin to kill...

    3. Re:there is proof by pesho · · Score: 5, Informative

      Soap will actually kill Gram-negative bacteria, by dissolving their cell membranes. Gram-positive bacteria, yeast, fungi, etc are going to be harder to kill by soap. Any spores will be completely resistant. This however is not the point. You use the soap not to kill the bugs, but to wash them away.

  3. There is good bacteria too. by jellomizer · · Score: 5, Informative

    We are covered with bacteria a lot of it is rather helpful to us. So by using Anti-bacterial soap we do kill off the good bacteria too.
    Or worse we make the good Bacteria go bad. Because when we try to kill it, it gives off chemicals to try to protect itself which then turns harmful for us.

    We are better off washing our hands with normal soap, which washes away large colonies of bacteria, but doesn't kill them off, as well as foreign contaminates that could cause problems too.

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    1. Re:There is good bacteria too. by AthanasiusKircher · · Score: 4, Interesting

      We are covered with bacteria a lot of it is rather helpful to us. So by using Anti-bacterial soap we do kill off the good bacteria too.

      Absoolutely. The hygiene hypothesis suggests that those "good" bacteria not only play a role in things like digestion, etc., but also may be necessary for a normal functioning immune system.

      It may be even worse than that. Triclosan, one of the most common compound used in antibacterial soaps, tends to hang out in the environment for quite a while. What is the effect of large amounts of antibacterial stuff ending up in our systems and the environment around us? Could it eventually disrupt the growth of the normal bacterial biome around us, which is necessary to the normal functioning of our bodies?

      I don't think we should be alarmist about this, but it's something at least worth studying, and perhaps being a bit cautious about.

  4. Re:Logic by LunaticTippy · · Score: 5, Informative

    That's your wrong one. Superbugs are resistant to antibiotics, not the pointless stuff they put in soap these days. There's no way for a bacteria to become resistant to penicillin by being exposed Triclosan. That's just silly.

    Your casual dismissal of this possibility seems logical but is incorrect. There are numerous studies of cross resistance between triclosan and antibiotics, Here is one showing several bacteria that evolve resistance to antibiotics after being exposed to sublethal doses of triclosan. This implies that dosing our wastewater with low levels of triclosan is reckless and had better have strong evidence that it does some good. It is definitely doing some bad!

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  5. Dioxin Funtime by Kagato · · Score: 4, Interesting

    The biggest issue the the common antibacterial agent in soaps combines with other household cleaners water treatment chemicals to produce a dioxin like substance. Studies are starting to showing negative environmental impacts to takes and rivers as a result.

  6. Re: Testing Inaccurate? by EvilSS · · Score: 5, Informative

    Because washing your hands does not "kill' bacteria, it dislodges them so they can be washed away. The demonstration is extremely valid in demonstrating how long it actually takes to clean the hands of something that tends to cling. Is it a perfect model? No. It is, however, a very good educational too. Most people do not wash their hands properly because they a) miss regions such as the wrist or the thumb and b) they do not wash long enough to be effective. It's the reason that most hospitals have hand washing education programs for their staff.

    http://www.cdc.gov/handwashing/

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  7. Triclosan vs. isoniazid & ciprofloxacin by Valdrax · · Score: 5, Informative

    the "anti-bacterial" ingredients are chlorinated organics, they just poison bacteria. they are not in any way related to antibiotics and thus do not in any way conribute to resistance to antibiotics any more than your chlorinated kitchen cleanser does.

    All antibiotics poison bacteria in some way, and several are chlorinated hydrocarbons, e.g. vancomycin, clindamycin, clofazimine, chloramphenicol, thiamphenicol, etc. Antibiotics are widely varied category of chemicals, and while triclosan isn't directly related to any families I'm aware of, that doesn't mean that resistance to it would be useless against antibiotics that operate on the same system.

    A mutation capable of resisting the effects of one class of chemicals can often be useful for resisting very different chemicals that have the same effect. Triclosan works at higher, lethal concentrations by disrupting bacterial cell membranes. At lower concentrations it also suppresses fatty acid formation necessary for cell membrane creation by binding up two enzymes necessary for the process: ENR and NAD+. (This prevents reproduction but doesn't kill.)

    Isoniazid is one of our first-line treatments for tuberculosis. Interestingly, it also works by binding to NADH and then binding to ENR and blocking fatty acid synthesis. Studies have shown that some strains of isoniazid-resistant mycobacteria are also pretty resistant to triclosan as a result. Others aren't, because they developed mutations that affected other parts of the process of the drug's interaction. These are unrelated compounds, but a mutation that affects an enzyme they both act on can promote resistance to both.

    There is also evidence that evolution of triclosan resistance can increase resistance to ciprofloxacin. In that case, the mutation was to increase the expression of certain efflux pumps, used to pump toxic chemicals out of the cell. Turns out in that case that the same pump was used as part of the processes to eliminate both toxins.

    So, in summary, while there isn't any evidence that triclosan is responsible for anywhere near the damage that usage in livestock has done, it's probably not a good idea to keep using a chemical that has risks in a situation where it has little benefit because it can aid in the development of resistance for some antibiotics.

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  8. Re:Testing Inaccurate? by Krishnoid · · Score: 5, Funny

    You should wash your hands long enough to sing Happy Birthday(c) twice.

    That's long enough to scrub off the bacteria. Also, entirely coincidentally, long enough for the RIAA to get a fix on your position.