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Creating "Homo Minutus" — a Benchtop Human To Test Drugs

Science_afficionado (932920) writes "Vanderbilt University scientists reported significant progress toward creating 'homo minutus' — a benchtop human — at the Society of Toxicology meeting on Mar. 26 in Phoenix. The advance is the successful development and analysis of a human liver construct//organ-on-a-chip that responds to exposure to a toxic chemical much like a real liver. The achievement is the first result from a five-year, $19 million multi-institutional effort led by Los Alamos National Laboratory (LANL), to develop four interconnected human organ constructs — liver, heart, lung and kidney — that are based on a highly miniaturized platform nicknamed ATHENA (Advanced Tissue-engineered Human Ectypal Network Analyzer). The project is supported by the Defense Threat Reduction Agency. Similar programs to create smaller-scale organs-on-chips are underway at the Defense Advanced Research Projects Agency and the National Institutes of Health."

49 comments

  1. Meh. by fuzzyfuzzyfungus · · Score: 4, Funny

    I always just use orphans. Nobody seems to care about those.

    1. Re:Meh. by wonkey_monkey · · Score: 1
      --
      systemd is Roko's Basilisk.
    2. Re:Meh. by Anonymous Coward · · Score: 1

      Well, maybe if the church hadn't made it wrong to experiment on heathens, god would be happier.

    3. Re:Meh. by scorp1us · · Score: 1

      You can't experiment on kids like that. They are too resilient and you won't get good data. It's not soud. Use midgets instead, ginger midgets.

      --
      Slashdot's rate-of-post filter: Preventing you from posting too many great ideas at once.
    4. Re:Meh. by bitt3n · · Score: 1

      I always just use orphans. Nobody seems to care about those.

      The best part is, unlike breeding normal laboratory animals, all you need to make more orphans is a PTA meeting and an assault rifle.

    5. Re:Meh. by MickyTheIdiot · · Score: 1

      Ginger midgets aren't human. You fail it.

  2. Homo Minutus .. AKA by Anonymous Coward · · Score: 4, Funny

    Homo Minutus .. Also known as "that little faggot"

    1. Re:Homo Minutus .. AKA by Anonymous Coward · · Score: 2, Funny

      Yeah, buddy, that's his own hair.

    2. Re:Homo Minutus .. AKA by Anonymous Coward · · Score: 0

      That little faggot's got his own jet airplane.

    3. Re:Homo Minutus .. AKA by MickyTheIdiot · · Score: 1

      We're pinheads now
      We are not whole
      We're pinheads all
      Jocko homo

  3. So much effort... by Anonymous Coward · · Score: 1

    Why not just midgets?

    1. Re:So much effort... by Anonymous Coward · · Score: 0

      Why not just midgets?

      They are - midget homos.

    2. Re:So much effort... by Anonymous Coward · · Score: 0

      Why not just midgets?

      Competition from dwarf tossing.

    3. Re:So much effort... by hink · · Score: 1

      Cause midget is an unacceptable term. My son has dwarfism, and shit like that pisses me off.

      --
      - speaking only for myself, as always
    4. Re:So much effort... by Anonymous Coward · · Score: 0

      Does he look more like a christmas elf or a cookie elf?

    5. Re:So much effort... by Anonymous Coward · · Score: 0

      There's a beautiful place waiting for him in the California pron industry.

    6. Re:So much effort... by Anonymous Coward · · Score: 0

      I think both are wrong. I am guessing Kiebler.

    7. Re:So much effort... by Jmc23 · · Score: 1

      You have no problem with dwarfism? Why is midget unacceptable. I don't know about you, but a small fly sounds like a better comparison than a demonic spirit...

      --
      Don't complain about syntax, grammar, or spelling. There is no.hell like input on android.
  4. More info by MRe_nl · · Score: 4, Informative

    A homunculus is shaped from a mixture of clay, ashes, mandrake root, spring water, and one pint of the creatorâ(TM)s own blood. The materials cost 50 gp. The creatureâ(TM)s master may assemble the body or hire someone else to do the job.
    After the body is sculpted, it is animated through an extended magical ritual that requires a specially prepared laboratory or workroom, similar to an alchemistâ(TM)s laboratory and costing 500 gp to establish. If the creator is personally constructing the creatureâ(TM)s body, the building and ritual can be performed together.

    --
    "Kill 'em all and let Root sort 'em out"
  5. Rights by ketomax · · Score: 1

    What about the fundamental rights of these organs?

    1. Re:Rights by Anonymous Coward · · Score: 2, Funny

      They have the right to remain silent.

    2. Re:Rights by Anonymous Coward · · Score: 0

      Anything they say can and will be taken down and used as data.

  6. What about a joke ? by vikingpower · · Score: 2

    What with April 1st and so on... Anyways, tomorrow I will be in Prague, and will propose the job offer to the Golem. He's been jobless for centuries now.

    --
    Religous speak to God. Insane are spoken to by God. When all shut up, one can finally hear Shostakovich in peace
    1. Re:What about a joke ? by McGruber · · Score: 1

      What with April 1st and so on...

      Everyday is April Fool's Day with Slashdot Beta....

    2. Re:What about a joke ? by K.+S.+Kyosuke · · Score: 1

      I'm pretty sure he'd be offended by the "minutus" part, so let's hope he doesn't understand Latin. Just don't piss him off in Hebrew and you should be fine.

      --
      Ezekiel 23:20
    3. Re:What about a joke ? by vikingpower · · Score: 1

      He was quite polite to me, pointing out that Oracle had already hired him to shovel Big Data. "My salary is a hype, but I am in for the spell and the hype only, anyways". After which we drank one of those excellent Czech beers and went our separate ways.

      --
      Religous speak to God. Insane are spoken to by God. When all shut up, one can finally hear Shostakovich in peace
    4. Re:What about a joke ? by K.+S.+Kyosuke · · Score: 1

      "He was quite polite to me, pointing out that Oracle had already hired him to shovel Big Data"

      I'm pretty sure that's just a clever ploy:

      1) Hire Golem,

      2) Wait until the unstable Golem becomes enraged and destroys the neighboring IBM campus at Chodov,

      3) Disclaim everything. :-)

      --
      Ezekiel 23:20
    5. Re:What about a joke ? by vikingpower · · Score: 1

      Hm. The Golem leaving the Prague ghetto and wreaking havoc at Chodov, which belongs to the administrative district of Karlovy Vary - that would be an historical first. The defenestration of tradition, so to say :-)

      --
      Religous speak to God. Insane are spoken to by God. When all shut up, one can finally hear Shostakovich in peace
    6. Re:What about a joke ? by K.+S.+Kyosuke · · Score: 1

      Huh? Now what do Karlovy Vary have to do with anything? That's like saying that Olympia is the capital of Washington, D.C. I suspect you actually haven't been to Prague, being blissfully unaware where Oracle is. You might even have lied about having met the Golem! Now I feel hurt.

      --
      Ezekiel 23:20
    7. Re:What about a joke ? by vikingpower · · Score: 1

      Misunderstanding. There is a Chodov that is a suburb of Karlovy Vary. I did not check that there is also a Chodov close to Prague. In fact, I am not in the least interested in Oracle. Sorry for your hurt feelings. Next time I go to Prague ( which is slightly over 3 hrs driving from here ), I'll bring you a hair from the Golem. Do you feel better now ?

      --
      Religous speak to God. Insane are spoken to by God. When all shut up, one can finally hear Shostakovich in peace
  7. Prank by Redmancometh · · Score: 0

    Clearly an April fools' prank.

    1. Re:Prank by Anonymous Coward · · Score: 0

      Eh... I don't think it is. The articles cited are dated in March and it all looks very reasonable. They are not saying they are making whole humans, just growing organ systems to test toxic exposure.

  8. Yeah, so? by Anonymous Coward · · Score: 0

    I thought the 3D printing revolution meant stuff like this is a snap and just a bittorrent away? Why even post stories like this anymore? Anything, anything at all is possible now.

  9. This'll put my flatmate out of work by Anonymous Coward · · Score: 2

    That's we he does. He gets all the time off he wants, new drugs to try out, and money for nothing really. Has anyone considered the harm this will do?

    1. Re:This'll put my flatmate out of work by Sockatume · · Score: 1

      His job's probably safe; by all accounts this is going to be a superior alternative to animal and in-vitro studies. Given the simplicity of the model you'll still need to test drugs in actual people.

      --
      No kidding!!! What do you say at this point?
    2. Re:This'll put my flatmate out of work by mordjah · · Score: 1

      Not a bad gig, huh? He gets his money for nothin'.. Hell I bet he gets his chicks for free too!

      --
      "A mind reader? That sounds like sci fi." "Honey, we live on a space ship"
  10. What for? by Anonymous Coward · · Score: 0

    As long as there are enough rappers/hip hop fans that we can use, why bother?

    1. Re:What for? by Anonymous Coward · · Score: 0

      Just say blacks, dude. You look even dumber when you try to hide it behind something else.

  11. You didn't mention Prof. Folo Lirpa's contribution by eeyore · · Score: 1
    I understand Professor Folo Lirpa of the LMB Institute of Biology, Andorra, provided much of the early work on which the paper which you allude to in this article is based.

    Your insensitive clod rating has been appropriately adjusted.

    --
    E 8-)

  12. Ready for Christmas? by FatLittleMonkey · · Score: 1

    Will they be selling consumer versions as pets?

    --
    Science is all about firing a drunk pig out of a cannon just to see what happens.
  13. Autoplaying bullshit? by rebelwarlock · · Score: 1

    If you want to have a lame April Fool's joke, that's fine, but done have autoplaying beeping. There's no purpose for that, other than enticing people to track you down and beat you with a rusty pipe.

    1. Re:Autoplaying bullshit? by MickyTheIdiot · · Score: 1

      Didn't recognize morse code? Turn in geek card.

    2. Re:Autoplaying bullshit? by rebelwarlock · · Score: 1

      Morse code is not an acceptable excuse to be an annoying asshole.

  14. We already have Bench-top Humans! by Irate+Engineer · · Score: 1

    I believe they are called "monkeys".

    --

    Left MS Windows for Linux Mint and never looked back!

    Vote for Bernie in 2016!

  15. Anybody out there know morse? by darkonc · · Score: 1

    I'm presuming that the beeps are Morse code for some silly message, but I only know enough Morse to recognize it, not 'read' it.

    --
    Sometimes boldness is in fashion. Sometimes only the brave will be bold.
  16. "Homo Minutus" by Anonymous Coward · · Score: 0

    That's what your girlfriend called you when we were together last night.