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Hints of Life's Start Found In a Giant Virus

An anonymous reader points out this update on the world's largest virus, discovered in March. Chantal Abergel and Jean-Michel Claverie were used to finding strange viruses. The married virologists at Aix-Marseille University had made a career of it. But pithovirus, which they discovered in 2013 in a sample of Siberian dirt that had been frozen for more than 30,000 years, was more bizarre than the pair had ever imagined a virus could be. In the world of microbes, viruses are small — notoriously small. Pithovirus is not. The largest virus ever discovered, pithovirus is more massive than even some bacteria. Most viruses copy themselves by hijacking their host's molecular machinery. But pithovirus is much more independent, possessing some replication machinery of its own. Pithovirus's relatively large number of genes also differentiated it from other viruses, which are often genetically simple — the smallest have a mere four genes. Pithovirus has around 500 genes, and some are used for complex tasks such as making proteins and repairing and replicating DNA. "It was so different from what we were taught about viruses," Abergel said. The stunning find, first revealed in March, isn't just expanding scientists' notions of what a virus can be. It is reframing the debate over the origins of life."

6 of 158 comments (clear)

  1. "How big was it?" by cirby · · Score: 5, Funny

    "It was so big we had to sterilize our lab equipment with a hammer."

  2. Re:What is life? What is a virus? by radtea · · Score: 5, Insightful

    Then, in that case, what separates pithovius from the prokaryotes?

    Structure, from the sound of it, although mostly this is people committing various fallacies of reification and making false claims of "natural kinds".

    Everything is a continuum. Humans divide the continuum up using acts of selective attention. The only infinitely sharp edge is the edge of our attention (because we scale the edge to match the scale we are attending to, so whatever scale we are attending to seems to have a sharp division between the things we are selecting out.)

    "Species" do not have particularly crisp boundaries in the general case: they fade into each other, and we draw edges around them in more-or-less arbitrary ways. When we find new varieties we can either create new categories (by drawing new edges) or lump them into old categories (by moving old edges). Which move is to be preferred depends on the purposes of the knowing subject.

    --
    Blasphemy is a human right. Blasphemophobia kills.
  3. Re:What is life? What is a virus? by Anonymous Coward · · Score: 5, Informative

    There are many differences between viruses and prokaryotes, but the main thing that seperates them from life is that they don't have ribosomes (https://en.wikipedia.org/wiki/Ribosome). Ribosomes are necessary for the production of proteins and no known virus encodes thier own ribosomes (they use the ones from their host cell). Some viruses, such as the one mentioned in the link, do encode genes to make some tRNA (needed for translating the genetic code into protein).

  4. Re:Yet another proof creation doesn't work! by sumdumass · · Score: 5, Insightful

    Why does there need to be a creationist explanation?

    Do you really understand what creation means? It means something was created and in the case of religious creation, everything was. Why was it created? It's hard to say but nothing here is proof that creation doesn't work. It's just evidence that creation isn't needed to work. It's like a car, you can use a key to start it but you can also hot wire it and start without a key. That doesn't mean the key no longer works- it just may no longer be necessary to work in order to start the car.

    In fact, if you follow the religious examples (creationist), god gave man dominion over his creations. He also gave him knowledge. And we know in the new testament, that Jesus says God is still working and so was he. So in essence, you would search and find an understanding that didn't require the need for a God to create anything in order to understand it and have dominion (rule) over it. We also know that God gave us free will and you will either go to God or reject him/her. Nothing prevents anything from being created when a being is above the laws of nature that we are bound by and understand, including our understanding of those creations which may be by design of the creation.

    Expecting a supernatural explanation for natural events and understandings is not very scientific.

  5. Re:What is life? What is a virus? by psnyder · · Score: 5, Informative

    Uh, they most certainly have extremely crisp boundaries. Species are classified by the ability of two organisms to breed with one another.

    The "Species problem" shows this not to be the case. The specific issue you mention is in the introduction:

    "Another common problem is how to define reproductive isolation, because some separately evolving groups may continue to interbreed to some extent, and it can be a difficult matter to discover whether this hybridization affects the long-term genetic make-up of the groups."

    That being said, I was taught the same way as you and only learned differently when I started teaching it myself. Now when I explain classification, I try to intersperse phrases like "usually classified as..." or "One good way to classify it is...". I usually try to reinforce that there are many ways to classify, show them the most common way(s), and encourage them to make their own classifications if those ways fail. This is especially prevalent in biology where phylogenetics (usually based on RNA, dividing groups into clades) is currently intermixing with more traditional taxonomy (usually based on morphological traits, dividing groups into Linnaean classification)[1].

  6. Re:Well by jandersen · · Score: 5, Informative

    I, for one, welcome our new virii overl...oh forget it, this meme is no longer funny.

    Virii? Nitpicking, I know, but that particular abuse of the language makes me cringe, it really does, because it is so bizarrely and emphatically wrong on far too many levels.

    Even if 'virus' had been the singular form of a latin word, the plural would not have been 'virii', with double 'i' at the end. 'Viri', possibly, but 'virii' would have to come from 'Virius', a personal name - check out:

    http://en.wikipedia.org/wiki/L...

    and

    http://en.wikipedia.org/wiki/V...

    Finally, from http://en.wikipedia.org/wiki/V...:

    Etymology

    The word is from the Latin virus referring to poison and other noxious substances, first used in English in 1392.[10] Virulent, from Latin virulentus (poisonous), dates to 1400.[11] A meaning of "agent that causes infectious disease" is first recorded in 1728,[10] before the discovery of viruses by Dmitri Ivanovsky in 1892. The English plural is viruses, whereas the Latin word is a mass noun, which has no classically attested plural. The adjective viral dates to 1948.[12] The term virion (plural virions), which dates from 1959,[13] is also used to refer to a single, stable infective viral particle that is released from the cell and is fully capable of infecting other cells of the same type.[14]

    IMO, since 'virus' is a modernism - an old word used in a completely new way - it is reasonable to treat it grammatically as a modern word: one virus, multiple viruses, just like 'one bus, several buses' ('bus' from 'omnibus', but let's not go there). Apart from that, you would use a a nominative singular here: '... our virus overlords ...'