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"Fat-Burning Pill" Inches Closer To Reality

Zothecula writes with news that a fat burning pill may be on the horizon. "Researchers at Harvard University say they have identified two chemical compounds that could replace "bad" fat cells in the human body with healthy fat-burning cells, in what may be the first step toward the development of an effective medical treatment – which could even take the form of a pill – to help control weight gain. Not all fat is created equal. While white fat cells store energy as lipids and contribute to obesity, heart disease and type 2 diabetes, the less common brown fat cells pack energy in iron-rich mitochondria, have been shown to lower triglyceride levels and insulin resistance in mice, and appear to be correlated with lower body weight in humans. Brown fat makes up about five percent of the body mass of healthy newborns, helping them keep warm, and is still present in lower quantities in our neck and shoulders as adults, where it helps burn the white fat cells."

7 of 153 comments (clear)

  1. brown fat cells by Anonymous Coward · · Score: 5, Funny

    why you gotta be racist?

    1. Re: brown fat cells by ZackSchil · · Score: 5, Funny

      In this context, the brown fat cells are the good ones. Some of my best friends are brown fat cells.

  2. Re:Magic Pill - Self Discipline by DirePickle · · Score: 5, Insightful

    There's a certain subset of people for whom that is just never going to happen, or periods in lives where that's not going to happen. If we can make a magic pill, is that terrible? It's the future, let's take advantage.

  3. Re:Magic Pill - Self Discipline by timeOday · · Score: 5, Insightful

    What are your feelings on birth control? Similar?

  4. Re:Magic Pill - Self Discipline by Anonymous Coward · · Score: 5, Insightful

    Unfortunately it's not that simple. For some maintaining a reasonable weight means always being hungry. I don't think you realize this (I personally lost 60lb and have to work hard to keep it off) but it can be very miserable always being hungry. Always having that pain in the back of your mind and stomach. For some people it's too much to handle and I personally don't blame those who eat too much if they face this; it's better to enjoy food and be fat if the alternative is being miserable and always in pain. It's like complaining why people with depression just aren't happy; the same applies to why some overweight people don't stop being hungry.

  5. Re:Magic Pill - Self Discipline by diakka · · Score: 5, Insightful

    While I agree with most of what you said, the message has a callousness that will likely cause it to fall on deaf ears. Also, to imply that it's easy or simple just to eat less or control your appetite is a bit condescending to those who have a difficult time with this. Most people lack an awareness about their appetite and take a very reactive approach to satisfying their hunger. But the truth of the matter is that sugar and carbohydrates can rule us with the fierceness of a drug or alcohol addiction. I myself have never had a trouble knowing when to stop drinking, but others, due to genetics, can't have just one.

    Once I finally started to treat sugar as a drug addiction, I finally started having the success at controlling my weight. I'm currently 60lbs lighter than my peak and have a six pack for the first time in my life at 39. Now that I know how to do it, it's easy, but figuring it out and changing my habits was not.

    So while I do sympathize with overweight people who struggle with controlling their appetite, I do find the fatalistic attitude that many overweight people have adopted to be quite annoying, and potentially harmful to others around them.

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    -- Knowledge shared is power lost. -- Aleister Crowley
  6. Re: Restrict carbs, not calories by taiwanjohn · · Score: 5, Informative

    I've been losing weight steadily for several months now, on a low-carb, high-fat, "paleo" lifestyle which includes light exercise and intermittent fasting. I do not pay any attention to calories whatsoever, I only avoid carbs and eat as much "real food" as I feel like, meaning single-ingredient, natural, fresh-cooked or raw products, as opposed to the processed "edible food-like substances" which occupy most of the shelf space in a modern supermarket.

    In terms of caloric intake, my diet is about 75~80% fat, 15~20% protein, and 5~10% carbs.

    I eat a lot of the following:
    Raw veg: carrot sticks, celery, broccoli, cauliflower, salad.
    Cooked veg: spinach, cabbage, sprouts, etc..
    Fermented veg: dill pickles, sauerkraut
    Dairy: butter, cream, cheese, cream-cheese, sour cream
      - Do eggs count as dairy? I eat about two per day.
    Nuts: almonds, walnuts, pistachios, etc..
    Meat: the fattier the better, especially organ meats
    Fish: the fattier the better.

    I avoid all processed foods and carbs in particular: Sugar, soft drinks, fruit juice, bread, pasta, starchy veg (eg. potatoes)... and also "somewhat avoid" legumes in general and soy products in particular.

    As for exercise, I don't have a regime or program, I just live in a walkable city with great public transpo, so I end up walking a couple miles per day on average. I also started using a stand-up desk last spring. I've been losing a steady 1lb per week for the last half year, and am well on the way to my target by next summer.

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    XML is like violence. If it doesn't solve your problem, you're not using enough of it. --AC