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Researchers Accidentally Discover How To Turn Off Skin Aging Gene
BarbaraHudson sends this excerpt from The Province:
While exploring the effects of the protein-degrading enzyme Granzyme B on blood vessels during heart attacks, professor David Granville and other researchers at the University of British Columbia couldn't help noticing that mice engineered to lack the enzyme had beautiful skin at the end of the experiment, while normal mice showed signs of age. The discovery pushed Granville's research in an unexpected new direction.
The researchers built a mechanized rodent tanning salon and exposed mice engineered to lack the enzyme and normal mice to UV light three times a week for 20 weeks, enough to cause redness, but not to burn. At the end of the experiment, the engineered mice still had smooth, unblemished skin, while the normal mice were deeply wrinkled.
Granzyme B breaks down proteins and interferes with the organization and the integrity of collagen, dismantling the scaffolding — or extra-cellular matrix — that cells bind to. This causes structural weakness, leading to wrinkles. Sunlight appears to increase levels of the enzyme and accelerate its damaging effects.
The researchers built a mechanized rodent tanning salon and exposed mice engineered to lack the enzyme and normal mice to UV light three times a week for 20 weeks, enough to cause redness, but not to burn. At the end of the experiment, the engineered mice still had smooth, unblemished skin, while the normal mice were deeply wrinkled.
Granzyme B breaks down proteins and interferes with the organization and the integrity of collagen, dismantling the scaffolding — or extra-cellular matrix — that cells bind to. This causes structural weakness, leading to wrinkles. Sunlight appears to increase levels of the enzyme and accelerate its damaging effects.
Or is the rest of the body "not aging "also?
Probably not, but skin is a LOT of the body. Hey at the least you could end up being a completely crippled , but awfully handsome , 90yo.
welcome our new handsome mice overlords
My skin cream is not only anti-aging, but it can also be used to power my home cold fusion power generators!
The next version will also be able to do teleportation via quantum entanglement.
I challenge any Slashdotter to come up with a better product than that!
Schroedinger's Brexit: The UK is both in and out of the EU at the same time!
In fact, you have a beautiful fur, but you can only eat like a mouse.
Das died in 2013."
So, the man who allegedly invented anti-aging has died? Talk about bad PR.
-- Make America hate again!