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Ancient Viruses Altered Human Brains

giulioprisco writes: A new study from Lund University in Sweden (abstract) indicates inherited viruses that are millions of years old play an important role in building up the complex networks that characterize the human brain. The Lund study shows that retroviruses seem to play a central role in the basic functions of the brain — over the course of evolution, the viruses took an increasingly firm hold on the steering wheel in our cellular machinery. In particular, the retroviruses seem to play an important role in the regulation of which genes are to be expressed, and when."

18 of 110 comments (clear)

  1. WSB by Anonymous Coward · · Score: 4, Insightful

    William Burroughs figured this out decades ago.

  2. Re:Run! by Tablizer · · Score: 3, Funny

    Based on our collective voting patterns, YES.

  3. Re:[bleep] have the CURE for the VIRUS. by Tablizer · · Score: 4, Funny

    This poster is likely a specimen having a recently-infected brain that may be ideal for studying this phenomenon in its early stages.

  4. Agent Smith was Right by Fire_Wraith · · Score: 5, Interesting

    Agent Smith: "I'd like to share a revelation that I've had during my time here. It came to me when I tried to classify your species and I realized that you're not actually mammals. Every mammal on this planet instinctively develops an equilibrium with the surrounding environment, but you humans do not. You move to an area and you multiply and multiply until every natural resource is consumed. The only way you can survive is to spread to another area. There is another organism on this planet that follows the same pattern. Do you know what it is? A virus. Human beings are a disease, a cancer of this planet; you are a plague and we are the cure."

    1. Re:Agent Smith was Right by plover · · Score: 3, Funny

      Put on your best Hugo Weaving voice and imagine Elrond saying "Hobbits ... are a disease; and we are the cure."

      --
      John
    2. Re:Agent Smith was Right by dasunt · · Score: 5, Interesting

      Agent Smith: "I'd like to share a revelation that I've had during my time here. It came to me when I tried to classify your species and I realized that you're not actually mammals. Every mammal on this planet instinctively develops an equilibrium with the surrounding environment, but you humans do not.

      Cute sentimentality, but considering how obviously untrue it is, that monologue always bugged me.

      First off, what areas have humans consumed so many natural resources that they can no longer survive there? About the only arguable cases I can think of is areas of desertification - and even then, humans do manage to live there.

      Second, mammals have no instinct to come to an equilibrium with their environment. E.g. rabbits in Australia - introduced a century ago, and definitely did not come to an homeostasis with the environment they found - instead, growing so numerous that they are a serious ecological problem.

    3. Re:Agent Smith was Right by Dutch+Gun · · Score: 4, Funny

      Pfft, never let facts get in the way of a good monologue.

      --
      Irony: Agile development has too much intertia to be abandoned now.
    4. Re:Agent Smith was Right by QilessQi · · Score: 3, Funny

      "I'm going to enjoy watching you die, Mister Baggins."

      "My name... is BILBO."

    5. Re: Agent Smith was Right by Anonymous Coward · · Score: 4, Insightful

      Better read Collapse by Jared Diamond before you get all cuddly with yourself. If that doesn't work for you, pick up a copy of The Limits to Growth: The 30 Year Update.

      If you don't like either of those, then look at the projections from the National Security Council regarding the future of global geopolitical stability once climate change has really kicked in. Why do you think humans are considered (by ourselves) to be the world's most 'successful' species, anyway? Ya think it has anything to do with the upcoming 6th major extinction event?

      Cultivate some more viri, will ya.

  5. Re:[bleep] have the CURE for the VIRUS. by FatdogHaiku · · Score: 3, Funny

    I can't removatize Bushificationisms from my head brain. Should I visitify a therapisterizer?

    A thrud xposyer will helpificate this problemification....

    --
    You have the right to remain sentient. If you give up the right to remain sentient, you will be elected to public office
  6. Sex, radiation and now viruses by Anonymous Coward · · Score: 5, Interesting

    A few years ago New Scientist had an interesting article that made me look at viruses in a different light.
    It basically said that viruses allow different species to exchange genetic material beyond what would be possible with
    sex alone. They had some example like the development of the placenta :
    http://blogs.discovermagazine.com/loom/2012/02/14/mammals-made-by-viruses/

  7. Re:Neuronal Tumors by ColdWetDog · · Score: 4, Informative

    The article lies. It says, "[t]he reason the viruses are activated specifically in the brain is probably due to the fact that tumours cannot form in nerve cells, unlike in other tissues."

    Leaving aside the awkward phrasing ("form _in_ nerve cells" [emphasis added]), it turns out that 1% of brain tumors are neuronal tumors. "Tumors of the central nervous system that contain abnormal neuronal elements, termed neuronal tumors, make up approximately 1% of all brain tumors." (http://pubs.rsna.org/doi/pdf/10.1148/radiographics.22.5.g02se051177)

    That said, I think I understand the gist of the argument. But I didn't know that neuronal tumors were so rare (or supposedly impossible, according to TFA) and felt compelled to fact check that assertion.

    I think it may refer to the fact that neural derived tumors typically form from the neural support cells (glial cells, astrocytes) rather than the axons and dentrite of a 'nerve cell'. Lousy phrasing and really a stretch as far as significance.

    Which segues into nicely hyperbolic title in TFA. What the research shows is that retroviral-derived sequences have some interesting control factors that are different from other cells. To intimate that this has anything to do with intelligence or even brain function is rather a stretch. It's a shame because the findings (a novel control pathway in the brain) is interesting all by itself.

    Sigh.

    --
    Faster! Faster! Faster would be better!
  8. Re: Now the anti-vax crowd by Ukab+the+Great · · Score: 4, Funny

    Good luck with that. The raw milk they drink gives them super strength and their excellent homepathy will repair any damage.

  9. Error in TFA by Prune · · Score: 5, Informative

    From the article: "tumours cannot form in nerve cells". This, of course, is BS that was discredited a couple of years ago: http://m.medicalxpress.com/new... Perhaps we should have a Slashdot discussion on lazy scientists failing to keep up with developments in their own field. If you write without bothering to read, you end up with... well, something like Slashdot...

    --
    "Politicians and diapers must be changed often, and for the same reason."
  10. Re:lost hair by Gavagai80 · · Score: 3, Informative

    Unfortunately for your randomly invented theory, homo sapiens developed their brains in warm parts of Africa.

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    This space intentionally left blank
  11. Easter island by aepervius · · Score: 4, Insightful

    what areas have humans consumed so many natural resources that they can no longer survive there

    There isn't that many, but i think easter island would qualify.

    --
    C. Sagan : A demon haunted world:
    http://www.amazon.com/gp/product/0345409469/
    visit randi.org
  12. Re:Thank you by drinkypoo · · Score: 4, Interesting

    I think we should convert to a very successful time in Athens, where politicians were selected by lottery... Out with the political class and the people that can buy them.

    Only a portion of the politicians were selected by lottery, and only racially privileged male landowners were eligible to serve or had a vote. Once elected, they could still be bought. Their society was based on slavery. Still want to convert back to Athenian government? Guess what? It was an oligarchic republic just like what we have now.

    --
    "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
  13. Re: Now the anti-vax crowd by jbengt · · Score: 4, Funny

    You would think that homeopaths would heartily endorse vaccines, as they seem to be one of the few treatments that successfully use small dose solutions of material that causes similar symptoms to treat (prevent) the actual disease.