Slashdot Mirror


Microbots Deliver Medical Payload In Living Creature For the First Time

Zothecula writes: Researchers working at the University of California, San Diego have claimed a world first in proving that artificial, microscopic machines can travel inside a living creature and deliver their medicinal load without any detrimental effects. Using micro-motor powered robots propelled by gas bubbles made from a reaction with the contents of the stomach in which they were deposited, these miniature machines have been successfully deployed in the body of a live mouse.

41 comments

  1. NANOMACHINES, SON by Anonymous Coward · · Score: 0

    NANOMACHINES, SON

  2. Give an warm welcome by Anonymous Coward · · Score: 0

    to our little overlords

  3. Here we go by Russ1642 · · Score: 3, Interesting

    This will be a revolution in medicine.

    1. Re:Here we go by Anonymous Coward · · Score: 0

      begun, the nanobot wars have...

      'Citizen, what possible objection could you have to an absolutely undetectable nanobot crawling up your butt and into your brain for required monitoring? You aren't harboring anti-establishment thoughts, are you, Citizen ? Then you have nothing to worry about... until you do.'

  4. this is by Anonymous Coward · · Score: 0

    Badass. Nothing more to say.

  5. The gas used is hydrogen by cruff · · Score: 3, Funny

    Oh, the humanity! All of those mice suffering hydrogen explosions when things get out of control!

    1. Re:The gas used is hydrogen by gstoddart · · Score: 1

      The extermination industry, however, sees great promise in the control of rodents.

      --
      Lost at C:>. Found at C.
  6. Resistance is futile by Anonymous Coward · · Score: 1

    That's how the Borg got started once again Star Trek predicts the future

    1. Re:Resistance is futile by Anonymous Coward · · Score: 0

      Please. As usual, video games were first.

  7. Since I have nowhere else to ask by Anonymous Coward · · Score: 0

    Where did the checkbox go for "you are eligible to disable ads"?

    Excellent karma, same as it has been for years, just did two rounds of mod points this week and last, and then, bam, today, ads EVERYWHERE. Thanks for reminding me to install noscript, but what the hell Slashdot?

    1. Re: Since I have nowhere else to ask by Anonymous Coward · · Score: 0

      The data feed from healthcare.gov must have come online today.

    2. Re:Since I have nowhere else to ask by Rhywden · · Score: 1

      Must be you. I still have that check box.

    3. Re:Since I have nowhere else to ask by Anonymous Coward · · Score: 0

      Still there for me. I occasionally see ads popping up even while the checked checkbox is plainly visible. And earlier in the week, there was an episode where all ads were hidden, except for a row of obnoxious image ads across the BOTTOM of the main page. I guess Dice doesn't think Slashdot is broken enough yet.

    4. Re:Since I have nowhere else to ask by Hussman32 · · Score: 1

      You posted as AC, I'm sure you've checked to see if you are logged in...right?

      --
      "Who are you?" "No one of consequence." "I must know." "Get used to disappointment."
    5. Re:Since I have nowhere else to ask by Anonymous Coward · · Score: 0

      Yes. I had to check the box to post as an AC, so I'm pretty sure I'm logged in. That, and my username is up at the top and on the side...

      No sense risking a flood of -1 downvotes on my well-burnished name when I'm just trying to ask a question.

  8. Better then oral-b by Oil_Tan · · Score: 0

    Nanbots for cleaning teeth while sleeping.

  9. Less impressive... by Anonymous Coward · · Score: 0

    ...when you realize that the "medical payload" was an itemized bill for medical services.

  10. Metal Gear!? by Anonymous Coward · · Score: 0

    It cant be!

  11. Really?! by Anonymous Coward · · Score: 3, Insightful

    Now this is pretty amazing, but...

    they are no more 'robots' than early Chinese fireworks were space probes. No guidance, no programming, just very clever manufacturing and good chemistry. Micro-motors are a big deal, but these aren't robots by any stretch.

    1. Re:Really?! by Paradise+Pete · · Score: 1

      What do you suggest they be called?

    2. Re:Really?! by jklovanc · · Score: 1

      Unguided delivery device.

    3. Re:Really?! by hcs_$reboot · · Score: 1
      --
      Slashdot, fix the reply notifications... You won't get away with it...
    4. Re:Really?! by n0w4k · · Score: 2

      The authors call them "micromotors". And that's perfectly justified; they have autonomous propulsion, but it's quite random. It's more or less like a car without a driver, just moves here and there randomly and gets stuck in a wall if it hits one. And that's how the delivery works in the paper; it's not directed at all.

      It will be insanely difficult to make active micro/nanobots which can be programmed or controlled in real time. It's just like making a living cell, inventing new biology. It will be way easier to create micro/nanoparticles which have some recognition units on their surface and attach/penetrate specific cells or tissues and then release their cargo. In fact there's been lot of progress in that field in recent years (nanoparticles conjugated with antibodies and stuff like that). But that is still a diffusion-based delivery. When it comes to active delivery, I guess the easiest way to "drive" them inside a human body is by magnetism (using magnetite nanoparticles).

  12. Raquel Welch by turkeydance · · Score: 1

    reference her, however and whenever it's possible. what a Fantastic Voyage.

  13. How do they do that? by AndyKron · · Score: 1

    How do the motors find their way to the stomach if they're already in the stomach?

  14. Microtubes... by seven+of+five · · Score: 1

    Calling these things nanobots or microbots is misleading. They're little tubes propelled by hydrogen gas bubbles. No onboard or remote intellegence or control of any kind really. Micro-torpedoes maybe.

    1. Re:Microtubes... by colordotmatrix · · Score: 0

      Calling these things nanobots or microbots is misleading. They're little tubes propelled by hydrogen gas bubbles. No onboard or remote intellegence or control of any kind really. Micro-torpedoes maybe.

      Small tubes with a flatulence problem?

    2. Re:Microtubes... by ShanghaiBill · · Score: 1

      No onboard or remote intellegence or control of any kind really. Micro-torpedoes maybe.

      Torpedoes have depth sensors and gyroscopes. Many also have sonar and magnetic sensors.

  15. Hype by jklovanc · · Score: 3, Informative

    The motors made their way to the mice's stomachs, embedded in their stomach linings, and released their tiny payloads: nano-size flakes of gold.

    No, the motors were swallowed by the mouse where they interacted with the acid in the stomach and began to move. Some of them eventually encountered the stomach lining where they embedded themselves. There was no payload release.

    The research represented a major step toward putting microbots to work in human medicine, where they could one day ferry drugs efficiently into specific organs or even specific cells.

    These are motors with a payload not microbots.
    Here are a few issues;
    They only work in an acid environment.
    This method could not be uses in blood supply as it produces gas which could cause an embolism.
    They have no way of discerning where they are. To deliver a drug to a specific point that is necessary.
    This may be a step to delivering drugs to the stomach or intestines but not really applicable to the rest of the body.

    1. Re:Hype by Lehk228 · · Score: 1

      delivering drugs to the stomach

      aka, a pill

      --
      Snowden and Manning are heroes.
    2. Re:Hype by jklovanc · · Score: 2

      The only difference is that a pill is passive while this method actively embeds objects into the stomach wall.

    3. Re:Hype by fahrbot-bot · · Score: 1

      delivering drugs to the stomach
      aka, a pill

      Beats the alternative delivery method (see the image AltText)

      --
      It must have been something you assimilated. . . .
  16. How are these things "bots"? by sbaker · · Score: 3, Informative

    So it looks like these things are basically zinc-lined tubes...no sensors, no guidance, no controls, no electronics, no communications or intelligence of any kind.

    How is that a "bot"?

    The gizmag report (second link in the story here) has a very beautiful picture of something which looks like a proper robot...but the other two links show simple cylinders.

    I could imagine it being a motor for a bot...but it's nowhere *REMOTELY* near being an actual robot, not by any stretch of the imagination.

    Look...this is an impressive achievement, it's very clever and I'm sure it has some very neat applications - but let's not over-sell it?

    Argh!

    --
    www.sjbaker.org
  17. Was Dennis Quaid there? by colordotmatrix · · Score: 0

    Or was he inside the shot?
    :-)

  18. The gut is still considered... by joocemann · · Score: 2

    ... outside world. From mouth to anus, you are like a squiggly wet cylinder of slimy secretions and supple absorptive tissues.

  19. Safe plastic by manu0601 · · Score: 1

    From TFA

    The chemicals they create when they dissolve—mostly a plastic, plus zinc, an essential mineral—are supposed to be safe for the body

    What plastic are we talking about? Polyethylene and polypropylene are safe. Polycarbonate and polystyrene are definitively not safe. The generic term "plastic" does not tell us much about safety.

  20. Challenge Accepted by Anonymous Coward · · Score: 0

    Polymophic Cancer Virus in C with Var'raq Extensions.

  21. Challenge Accepted by Anonymous Coward · · Score: 0

    Polymorphic RNA corruption worm with dream of immortality in C and Seer.

  22. wow by CryoKeen · · Score: 1

    This is quite an amazing breakthrough! I for one welcome our nano-machine enhanced cybernetic mice overlords.