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Two New Male Birth Control Chemicals In Advanced Stages

BarbaraHudson writes Researchers at the University of Kansas and Harvard are working to give men more choices for avoiding unwanted pregnancies. From the article: "H2-gamendazole keeps sperm from maturing. The unfinished sperm fragments are then reabsorbed into the testis, never ending up in the semen. 'If there's no sperm, the egg's not going to get fertilized,' says Joseph Tash, a reproductive biologist at the University of Kansas Medical Center. Almost two years ago, the FDA reviewed the compound, and now the agency wants Tash to investigate if the compound remains in the semen and whether that would harm a woman if it ends up in the vagina. Jay Bradner, working with other anti-cancer researchers at Harvard, discovered that the JQ1 molecule blocked a bromodomain in cancer cells, causing them to forget how to be cancer. One side effect is that JQ1 also obstructed a testicle-specific bromodomain called BRDT, making the sex cells that would otherwise produce sperm non-functional — mice treated with JQ1 can hump with abandon yet generate zero mouselings. Researchers are looking for a version of the molecule that works on the testicle protein only, to avoid any weird side effects."

16 of 369 comments (clear)

  1. Curing cancer by Anonymous Coward · · Score: 4, Insightful

    TFA: [...] discovered that the JQ1 molecule blocked a bromodomain in cancer cells, causing them to forget how to be cancer. [...] Researchers are looking for a version of the molecule that works on the testicle protein only, to avoid any weird side effects

    Since when slowing down cancer is a "weird side effect"? :D

    1. Re:Curing cancer by ColdWetDog · · Score: 3, Insightful

      The pharma industry doesn't like to make medicines that solve more than one problem at a time. It's difficult to monetize that efficiently.

      Your trolling, but you're wrong. If all you need to do is another Phase III study for a different indication, you're golden. There are a number of drugs on the market that have different trade names for different uses but are the same molecule. It's not quite the Holy Grail for big Pharma, but it is at least a big lottery win.

      --
      Faster! Faster! Faster would be better!
  2. This type of preventative would be awesome by burtosis · · Score: 5, Insightful

    This could really help men everywhere, there are a ton of options for women but very few for men. I can only hope when the day comes that it's viewed as a positive direction from all rights groups. Doubtful, but one can dream.

  3. Re:Not a fucking chance. by BarbaraHudson · · Score: 5, Insightful

    Birth control is a womens issue.

    You won't get a judge to agree with you if you accidentally father a child.

    I won't be putting any unknown chemicals into my body for HER sake.

    And yet you want her to put chemicals into her body for YOUR fun and enjoyment. Nice troll :-(

    --
    "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
  4. All well and good, but... by Anonymous Coward · · Score: 0, Insightful

    You just watch. The amount of false rape claims will skyrocket for a while when this hits the public, from the kind of women who try to "accidentally" get knocked up to ensnare men.

    "mmm yes it was so good. :) No no, don't worry about forgetting to pull out, I'll just flush myself out/I'm on the pill/it's not the right time of the month anyway/etc. [later] (Why the fuck is it always negative? Ugh... tomorrow for sure) [later] (Negative again?!) We need to talk. [one explanation later] WHADDAYA MEAN MALE BIRTH CONTROL?! SHENANIGANS! RAPE! RAAAAPE!!! POLICE HELP, HE RAPED ME!!!!!!!!!"

    Or the stuff will just get hung up in FDA approval for a while, long after all the bugs have been worked out.

  5. Re:Time for men's liberation by Anonymous Coward · · Score: 5, Insightful

    As moving targets and potential victims of the "women and children" state that will punish a Man to the ends of the Earth for having the audacity to father a child.

  6. Re:Not a fucking chance. by XxtraLarGe · · Score: 5, Insightful

    Birth control is a womens issue.

    You won't get a judge to agree with you if you accidentally father a child.

    I like how this issue is always 1-sided. It's a woman's choice if she wants to have an abortion, but the guy doesn't have a choice to not support the child if the woman wants to have it but he doesn't.

    --
    Taking guns away from the 99% gives the 1% 100% of the power.
  7. Sad For My Gender by Jason+Levine · · Score: 5, Insightful

    The number of responses here along the lines of "women always trick men into marriage by getting pregnant" or "birth control is a woman's responsibility" make me sad for my gender. I can't be the only man on Slashdot who 1) respects women (my wife and I both manage our portions of birth control together - I would never suggest that's HER job and not for me to be bothered with), 2) sees fatherhood as a positive outcome - not something that is only entered into via trickery, and 3) would like to see new birth control methods available on the market (whether or not this one would work for my wife and I aside, the more options the better). Can I?

    --
    My sci-fi novel, Ghost Thief, is now available from Amazon.com.
    1. Re:Sad For My Gender by Tyr07 · · Score: 5, Insightful

      You should be sad for humanity, because men or women, both do some pretty shitty things.

      That aside, women, rightfully in my opinion, call out that it's their body, they have the right to make choices that affect their body.
      Yet for everyone pointing a finger a men, what happened to this right to choose what happens to your body, what, you get the right to chose but don't have
      the responsibility?

      Male birth control is the right step forward for equality for men. You see, although all the more extreme fem groups are all looking at the CEO's and measuring their own personal wealth against it, deciding it's the old boys club, there are other areas that have inequity for men, such as decreased pleasure sexually to prevent pregnancy, the way the courts favor women for parenting, that family courts are HEAVILY populated by women, almost always a female judge with female representatives, and that men are on the hook for children women decide to keep or come to term.

      Well, this is one way we can make our own choices about what responsibilities we're going to accept and it will be out of a woman's hand, so I'm all for it.

    2. Re:Sad For My Gender by eepok · · Score: 5, Insightful

      People comment based on experiences or the stories of others.

      Women have, historically, had the socially-supported option of getting pregnant instead of being old and single or instead of entering the workforce. In fact, entering the workforce is still a relatively new concept for women and still not universal throughout the world. Men still have the socially-enforced expectation of tying one's finances to the mother of his children regardless of the involvement of those men in the lives of the children or the mother. This is a genuine hobbling of the uninvolved man's life post impregnation and thus fear of a coerced pregnancy is a significant fear amongst men. As a result, SOME men are suspicious of women when it comes to birth control.

      Thus, you shouldn't be surprised by pessimistic online comments reading as "Women trick men into marriage by getting pregnant".

      But it does not define the entirety of the population. It MAY describe a part of an aging population of experiences (the younger generation doesn't seem too keen on popping babies out), but by no means defines an entire community.

      You can see such patterns of experiences -> comments by taking a look at your own. Your experience with your wife (cooperative birth control expectations, a happy outlook on parenthood, etc.) will bias you towards believing that women have not/do not use pregnancy as a investment-- but it would also suggest that you're fairly far-removed from the lives your male peers if you cannot understand their fears.

  8. Re:Not a fucking chance. by Raseri · · Score: 4, Insightful

    I didn't realize straw men could father children. Thank you for enlightening us.

    --
    Writhe your naked ass to the mindless groove.
  9. Re:Time for men's liberation by flink · · Score: 4, Insightful

    It would be awesome if this could be part of a men's liberation movement, like how women were liberated in the 60s when the pill became available.

    Was it the pill that led to women's liberation? Or was it penicillin? The pill allows women to have sex without getting pregnant. Penicillin allowed people to have sex without getting diseases. AIDS has somewhat rolled that back.

    Before HIV, there was still always Herpes, Hepatitis, HPV.... e.g. anything viral. People were just more ignorant of STDs 50 years ago, but that doesn't meant they still weren't getting them. You're still going to want a condom on the first date no matter how many new types of contraception get invented.

  10. Re:Not a fucking chance. by XxtraLarGe · · Score: 4, Insightful

    Well guess what? Maybe you should have taken a little bit of responsibility by using a condom?

    That does not address the original issue. Would you find it acceptable for someone to say "Maybe you should have taken a little responsibility and not spread your legs" to a woman? If not, why is it o.k. to say that to the guy?

    --
    Taking guns away from the 99% gives the 1% 100% of the power.
  11. Re:Not a fucking chance. by d34thm0nk3y · · Score: 4, Insightful

    Because the only satisfactorily effective means of birth control are all in the hands of women, from the pill through the morning after pill to abortion

    Women are also in control of the global condom supply, apparently.

    How does something so completely wrong get modded so highly?

  12. Re:Time for men's liberation by serviscope_minor · · Score: 5, Insightful

    Sex is all about trust.

    No it ain't, it's about shagging.

    --
    SJW n. One who posts facts.
  13. Re:Time for men's liberation by Anonymous Coward · · Score: 3, Insightful

    Sex between equals involves trust, yes, but saying that it's "all about trust" is like saying that going to the movies is all about eating popcorn.