Being Overweight Reduces Dementia Risk
jones_supa writes Being overweight cuts the risk of dementia, according to the largest and most precise investigation into the relationship (abstract). The researchers were surprised by the findings, which run contrary to current health advice. The team at Oxon Epidemiology and the London School of Hygiene and Tropical Medicine analyzed medical records from 2 million people aged 55 on average, for up to two decades. Their most conservative analysis showed underweight people had a 39% greater risk of dementia compared with being a normal healthy weight. But those who were overweight had an 18% reduction in dementia, and the figure was 24% reduction for the obese. Any explanation for the protective effect is distinctly lacking. There are some ideas that vitamin D and E deficiencies contribute to dementia and they may be less common in those eating more. Be it any way, let's still not forget that heart disease, stroke, diabetes, some cancers and other diseases are all linked to a bigger waistline. Maybe being slightly overweight is the optimum to strike, if the recent study is to be followed.
Easy explanation: They die before they develop dementia...
Ahhh...the great dumpster continuum. Many a free computer will be found there. -- sowth (748135)
diabetes, heart failure, stroke & cancer are all better deaths than alzheimer's(or any of the neurodegenerative illnesses)
I guess we know where the phrase "anchored in reality" comes from.
-Styopa
Being overweight in MIDDLE AGE is good for preventing dementia.
No correlation has been proved with being overweight your entire life. Probably because the study examined people who were 55 at the start of the study.
So, put on a few pounds at the time of life when putting on a few pounds is pretty much natural, then ditch those extra pounds as you get past middle age and into old age.
"I do not agree with what you say, but I will defend to the death your right to say it"
Actually, studies tend to show that being slightly over weight reduces all-cause mortality compared to "normal".
http://www.ncbi.nlm.nih.gov/pu...
Your all-cause mortality rate for overweight, and grade-1 obese are roughly 0.95 times that for "normal" weight. However, being grade-2 obese or more is associated with a sudden, very rapid increase in mortality rate.
Basically, being slightly overweight isn't bad, and may even be pretty good. Being more-than-slightly overweight is really really really bad though.
Yeah because you die of a coronary from obesity prior to dementia forming.
This is literally the stupidest "health" article I have seen yet.
"If any question why we died, Tell them because our fathers lied."
So IOW, our calculation of what it means to be overweight is wrong, since the ideal weight is apparently higher than the established norm.
I'm protecting myself with soft, blubbery armor!
Across 2 million people with a median starting age of 55, BMI works just fine.
Why the hell can't it be related to higher free IGF-1 levels?
There are studies indicating that obese people have higher free IGF-1 levels.
http://www.ncbi.nlm.nih.gov/pu...
There are also studies saying that high levels of IGF-1 are linked to a lower risk of Alzheimer’s disease and subclinical brain atrophy:
http://www.neurologyreviews.co...
This study is interesting, but as it notes, most certainly needs further investigation. BMI is not the greatest metric to determine health, and I'm not surprised that those who are carrying some weight will be better over on a number of health markers.
Only if you define 'ideal weight' as one which reduces mortality by highest margin. If there would be a way to guarantee 200 years of body life by putting person in pharma coma for all that time, would it be 'ideal state' to go through live?
Mortality quality of life. Probably a lot of people will trade extra 1% of chance dying few years earlier, for 80% of having 10 last years of life bearable instead of being bed-bound.
Now, I'm not saying that being slight overweight neccesarily decreases quality of life (looking at what my weight-aware friends are eating I'm quite sure of opposite) or will make you a cripple. Just want to point out that there are more things to take into account that pure statistical mortality.
Pass the donuts!!
Have gnu, will travel.
This is a guess, but I suspect that people with just a *little* bit of extra fat content are better able to survive illness where they cannot eat or where they suffer from diarrhea or other digestive tract inflammation. I've also read somewhere that there's a theory that nerve cells and fat cells are relatively closely related, so perhaps when the lean individual gets ill, the body inadvertently starts trying to extract the energy from nerve cells in a fashion similar to what it does from fat, which effectively attacks the nervous system.
Obviously too much fat is very unhealthy, stressing the organs and the joints, but the definition of what's healthy has changed so many times over the last several decades that I don't know what to shoot for.
Do not look into laser with remaining eye.
BMI is NOT a good way to judge over and underweight. Tim S.
A competent epidemiologist would control for the "They die before they develop dementia" effect.
Given this is a peer reviewed study I think it hugely likely they controlled for that.
I wonder if sleep apnea is considered dementia in this context?
Sleep apnea is highly correlated with obesity at that age and it can give the sufferer a disturbingly
similar experience to senile dementia when severe and untreated.
No shit, they don't live long enough to GET dementia. You don't exactly see a lot of fat people at the retirement home - there's a reason for that.
"The tree of liberty must be refreshed from time to time with the blood of patriots and tyrants." ~Thomas Jefferson
Why is medical reporting so rife with them? They have to pass some science courses before becoming doctors, don't they? Why are so many medical studies reported as "we found a correlation so there must be a causation." Not only does correlation is not causation. Correlation do not imply causation.
Any guest worker system is indistinguishable from indentured servitude.
I.e. you die of diabetes, heart attack or a stroke before you could get demented.
We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
One thing that is well known is that shit like toxic heavy metals, that can circulate indefinitely in the body, tend to be safely captured by body fat and thereby stop being harmful for the duration of entrapment.
Conversely, one can surmise, that such toxins will continue their destructive process if there is little fat to trap them in.
This is about being "overweight" by body mass index(yes I looked), as opposed to body fat percentage. As such I'm going to ignore the whole study.You can easily have a higher than average BMI and still be very healthy.
If video games influenced behavior the Pac Man generation would be eating pills and running away from their problems.
Fat, dumb and happy.
Have gnu, will travel.
Maybe the fatter you are, the more diluted (in your body) the Alzheimer's-causing agents become, and the fewer that actually make it to your brain.