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Experimental Drug Targeting Alzheimer's Disease Shows Anti-Aging Effects (nextbigfuture.com)

schwit1 writes with news that researchers at the Salk Institute have found that an experimental drug candidate aimed at combating Alzheimer's disease has a host of unexpected anti-aging effects in animals. Says the article: The Salk team expanded upon their previous development of a drug candidate, called J147, which takes a different tack by targeting Alzheimer's major risk factor–old age. In the new work, the team showed that the drug candidate worked well in a mouse model of aging not typically used in Alzheimer's research. When these mice were treated with J147, they had better memory and cognition, healthier blood vessels in the brain and other improved physiological features.

"Initially, the impetus was to test this drug in a novel animal model that was more similar to 99 percent of Alzheimer's cases," says Antonio Currais, the lead author and a member of Professor David Schubert's Cellular Neurobiology Laboratory at Salk. "We did not predict we'd see this sort of anti-aging effect, but J147 made old mice look like they were young, based upon a number of physiological parameters."

2 of 101 comments (clear)

  1. I FORGOT to shove a GREASY YODA UP MY ASS! by Anonymous Coward · · Score: -1, Troll
    How to Shove a Yoda Doll up your ass! The 9 Step Greased Up Yoda Doll Shoving process. Go Linux! Tsarkon Reports

    9 steps to greasing your anus for Yoda Doll Insertion!
    v 4.97.3
    $YodaBSD: src/release/doc/en_US.ISO8859-1/yodanotes/9stepprocess.sgml,v 4.97.3 2015/9/3 15:42:20 tsarkon Exp $

    1. Defecate. Preferably after eating senna, ex lax, prunes, cabbage, pickled eggs, and Vietnamese chili garlic sauce. To better enhance the pleasure of this whole process, defecation should be performed in the Return of the Jedi wastebasket for added pleasure.
    2. Wipe ass with witch hazel, which soothes horrific burns. (Rob "CmdrTaco" Malda certifies that his lips, raw like beaten flank steak from nearly continuous analingus with dogs, are greatly soothed by witch hazel which makes it perfect for the anus after diarrhea.)
    3. Prime anus with anal ease. (Now Cherry Flavored for those butthole lick-o-phillic amongst you - very popular with 99% of the Slashdotting public!)
    4. Slather richly a considerable amount of Vaseline and/or other anal lubricants into your rectum at least until the bend and also take your Yoda Doll , Yoda Shampoo bottle or Yoda soap-on-a-rope and liberally apply the lubricants to the Yoda Doll/Yoda Shampoo/Yoda Soap-on-a-rope. You may need your gay squire/lover to help with this since your fat corpulent ass cannot do a self-reach-around.
    5. Put a nigger do-rag on Yoda's head so the ears don't stick out like daggers!
    6. Make sure to have a mechanism by which to fish Yoda out of your rectum, the soap on the rope is especially useful because the retrieval mechanism is built in.
    7. Pucker and relax your balloon knot. Doing Kegel exercises several times actuating the sphincter muscle and relaxing it will help prepare your ass for what is to come.
    8. Slowly rest yourself onto your Yoda figurine. Be careful, he's probably bigger than the dicks normally being rammed up your ass!
    9. Gyrate gleefully in your computer chair while your fat sexless geek nerd loser fat shit self enjoys the prostate massage you'll be getting. Think about snoodling with the Sarlaac pit. Read Slashdot. Masturbate to anime. Email one of the Slashdot editors hoping they will honor you with a reply. Join several more dating services - this time, you don't select the (desired - speaks English) and (desired - literate). You figure you might get a chance then. Order some fucking crap from Think Geek. Suck and gag on a Dr. Who sonic screwdriver like it was the Doctor's dick in your mouth. Get Linux to boot on a Black and Decker Toaster Oven. Wish you could afford a new computer. Argue that cheap-ass discount bin hardware works 'just as well' as the quality and premium hardware because you can't afford the real stuff. Make claims about how Linux rules. Compile a kernel on your 486SX. Claim to hate Windows but use it for World of Warcraft. Admire Ghyslain's courage in making that wonderful Star Wars movie. Officially convert to the Jedi religion. Talk about how cool Mega Tokyo is. Try and make sure you do your regular 50 story submissions to Slashdot, all of which get rejected because people who aren't fatter than CowboyNeal c
  2. Re:RTFM for once ... by Anonymous Coward · · Score: -1, Troll

    Ok that was amusing.

    Niggers are very amusing, as long as they don't live in your neighborhood. If they do, you're fucked. Get used to seeing cop cars with lights blaring at all hours of the night, listening to lard-ass single mothers screaming FUCK YOU to their toddler kids, neglected pit-bulls barking loudly at all hours of the night because they're tied to a tree and forgotten about for days at a time, and scary violent-looking young men visiting at all hours of the day next door. Oh then your own kids who are raised in a responsible loving household ask you why people act that way, what the word "cunt" means and why they keep yelling it, etc. Yay for Section 8 housing!

    The expansion of Section 8 Housing into white suburban neighborhoods == the belief that tossing several rotten apples into a big barrel of good apples is somehow going to repair the rotten apples. No. The few rotten apples are going to lower the value of all the good apples because you, in your moronic idealistic stupidity, failed to recognize and protect their value. This is nature. Nature doesn't care what you think is fair or equitable. Nature just is. Destroying the good and highly-ordered has always been much easier than reforming the shitty and disordered. It's physical law. We call it entropy. It's the way of things. If you don't like it, take it up with Science or the Creator God or whatever it is you believe in. The wise accept this and learn to work with it. The stupid pretend like it doesn't apply to them if they just wish real hard.

    It's an offensive internet troll ... until it happens to you. Remember that. Some of you just aren't going to understand certain things until you get affected by them. Pontificating about political correctness is easy when you don't have to live with the fallout. How many of you would cry and complain about what I said (while never disproving any of it, of course, because you can't) but would never consider moving to someplace like downtown Harlem? Yeah, that's what I thought. The worst kind of cowards are the ones who condemn others for not adhering to beliefs that they themselves are unwilling to even try and practice.