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Researchers Claim Success In Removing HIV From Living Cells (nature.com)
ffkom writes: A recent publication from German researchers claims success in removing the HI-Virus from living cells, showing a way to completely cure AIDS rather than just suppressing its symptoms (by lowering the amount of viruses) by permanent medication: "Current combination antiretroviral therapies (cART) efficiently suppress HIV-1 reproduction in humans, but the virus persists as integrated proviral reservoirs in small numbers of cells. To generate an antiviral agent capable of eradicating the provirus from infected cells, we employed 145 cycles of substrate-linked directed evolution to evolve a recombinase (Brec1) that site-specifically recognizes a 34-bp sequence present in the long terminal repeats (LTRs) of the majority of the clinically relevant HIV-1 strains and subtypes. Brec1 efficiently, precisely and safely removes the integrated provirus from infected cells and is efficacious on clinical HIV-1 isolates in vitro and in vivo, including in mice humanized with patient-derived cells. Our data suggest that Brec1 has potential for clinical application as a curative HIV-1 therapy."
Clinical trials are expected to start in Hamburg, Germany, soon.
We wont hear about it for the rest of our lives :P
Magic Johnson decided to share the cure
Are like battery/solar power articles. The best battery/HIV cure is just 2 years away. Always. But it never happens.
I am not surprised: Germans are good at eradicating living organisms.
Don't most of them start with a discovery like this. Just saying.
Next we'll have Nexus 6 replicants.
His erect penis,
Plugged inside a man's anus.
He is a faggot.
This is genetic engineering tech, applied to humans. Are you now going to require that all the HIV patients using this treatment wear labels? You know, the scarlet letter of the left.
If this actually works it could be one of the most important advances in human medicine for decades. Hopefully it actually works and isn't the typical vaporware HIV cure.
I haven't even RTFA yet, but I was wondering if this could have applications with other viruses that become long-term residents of the body. I'm thinking of things in the herpes family like... herpes, or chickenpox / shingles. The trick with most of these is long-term, mostly-dormant viruses hiding in the cells. If you can wake them up, the immune system can clear them, but they are effectively hidden inside the cells while quiescent.
N/T
WARNING: Smartphones have side effects--most of them undocumented.
Are you sure that it's not North Korea that said this?
Of course there's always a way to clean a body from a virus. Medicine has THOUSANDS of years of develeopment. The thing is... Every research laboratories depends on money to keep the whell rolling dude. So, the money causes interests on developing drugs for certain healing needs. If the menace of microcephaly opened a market that was iced for years, then I condemn both science and religion. Literally, I wouldn't have the will to live in this planet, neither mars or etc, in case of a reality where just interests on reality remains, instead of living to change reality itself with pain and gain.
until the common cold is a thing of the past?
Pharma companies are like banks, their livelihood depends on sucking money from their "customers" continuously and forever. One off cures could very well put them out of business and there will we be, depending on government to research "cures" for the masses?
Time is what keeps everything from happening all at once.
There are so many other illnesses that could benefit from the time and money spent on the effort to make it so men can fuck each other up the ass with impunity.
Only 88% of HIV are affected by this change. So not to be Debbie Downer, but as it is now, all this would do is change which strain is the most prevalent. 88% isn't good enough; Hell, 99.99% isn't good enough, as 'Life finds a way' (as far as viruses can be considered alive).
Gotta disagree with you saying that 88% isn't good enough.
1) If current measures are reducing transmission of HIV to R values (new cases per existing case) of something like 1.2 or lower, this could bring it below the threshold of being able to increase in numbers and thus speed eradication.
2) If 88% of CURRENT HIV+ are completely cured, drugs and resources saved can be concentrated on the remaining 12%, thus reducing R values even further, speeding eradication.
3) 88% cure rate is a pretty massive reduction in human suffering, isn't it?
--PM
Let them assholes die
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This will be expensive.