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Biden Unveils Open-Access Database To Advance Cancer Research (go.com)

An anonymous reader quotes a report from ABC News: Vice President Joe Biden unveiled a public database for clinical data on cancer on Monday that aims to help researchers and doctors better tailor new treatments to individuals. Overseen by the National Cancer Institute, the Genomic Data Commons starts with genomic and clinical data for 12,000 patients. The system is designed to increase sharing of information about the gene sequences of tumors and how patients with those tumors responded to specific treatments. "The information is scattered among different government and academic repositories. Most of it is out of the reach of scientists," Biden said. "We're bringing it into one space." Though easily searchable, the database includes protections for privacy and security, Biden said. He urged cancer experts gathered in Chicago to "upload your raw genomic data" to the system for use by fellow researchers. "All of you know it's the right thing to do," Biden said. "It's the quickest way for us to move forward. And it's not technically hard for us to do it." You can read the key features of the GDC via The White House here.

42 comments

  1. No, don't use an Access database for this!!! by Anonymous Coward · · Score: 1

    What? Oh, never mind.

  2. got tinfoil hat by Smiddi · · Score: 0

    Oh no, here come all the "cannabis cures cancer" nutcases

    1. Re:got tinfoil hat by ShanghaiBill · · Score: 1

      Oh no, here come all the "cannabis cures cancer" nutcases

      Cannabis doesn't directly cure cancer, but it can suppress the severe nausea caused by many chemotherapy drugs, which means more patients complete the course, which means more of them recover and survive.

      So far, the only downsides to cannabis legalization have been prison guard layoffs, and the extra burden on politicians that have to figure out how to spend all the money from dope sales taxes.

    2. Re:got tinfoil hat by Obfuscant · · Score: 1

      So far, the only downsides to cannabis legalization have been prison guard layoffs,

      Well, there are concerns about edibles and the dosages that people consume without realizing it. And turning "candy" into "drugs", thus creating issues for young people. (Kinda like the old candy cigarettes that aren't sold much anymore.)

    3. Re:got tinfoil hat by Anonymous Coward · · Score: 0

      WOW, you fucking shills don't even bother to wait or to construct some reasonable argument before throwing your garbage onto the nets. I hope they're not paying you much because that is some of the laziest fucking shilling I have ever seen.

      You need to do some soul searching if your life has to come to the point where you spread disinformation for money. Ironically, it is you who are a cancer of society.

    4. Re:got tinfoil hat by silentcoder · · Score: 2

      >So far, the only downsides to cannabis legalization have been prison guard layoffs, and the extra burden on politicians that have to figure out how to spend all the money from dope sales taxes.

      So the obvious solution is to use the dope sales taxes to fund employing the former prison guards in public works projects ?

      --
      Unicode killed the ASCII-art *
  3. Just another old guy... by Anonymous Coward · · Score: 0

    Swinging his power by his hips, trying to live forever.... Too bad he wasn't calling for this prior to ACA being passed, I wonder what that would have looked like.... Not that he has to deal with ACA since the upper class is too good to follow their own laws, you know.

  4. How do I sue by Anonymous Coward · · Score: 1

    .. for releasing my private genomic data? My samples were supposed to be protected!

    1. Re:How do I sue by Anonymous Coward · · Score: 0

      You forgot to mail a piece of your body to the Library of Congress to register the copyright!

  5. Those Rpepublucanz by Anonymous Coward · · Score: 0

    Will never allow this to happen. They batted us

    1. Re: Those Rpepublucanz by Anonymous Coward · · Score: 0

      That's how they be.

    2. Re: Those Rpepublucanz by Anonymous Coward · · Score: 0

      And they hate Biden even more than the people.

    3. Re: Those Rpepublucanz by Anonymous Coward · · Score: 0

      That's how they be.

      And just when I thought liberals couldn't get any dumber, I'm proven wrong again.

  6. Take your rmeds greenwow by Anonymous Coward · · Score: 0

    batted?

  7. Thanks, for all the DNA . . . by PolygamousRanchKid+ · · Score: 0

    Your Honorable Mr. Biden,

    We would like to thank you for your donation to our DNA database project! This has enabled us to refute claims, that your DNA could be found in the mouths of Oxford University pigs.

    Unfortunately, further analysis of your DNA data has proved that you are, in fact, John Wilkes Booth, the guy who shot Abraham Lincoln, or somebody. Of course, we would all like to see a peaceful solution to this problem. But if you want to go down in a hail of bullets . . . I can recommend a Vodafone store in the High Street of Westminster (which is a pseudo-UK-city near Hursley).

    . . . or, never mind . . . the Vodafone folks will never be there when you need them.

    --
    Schroedinger's Brexit: The UK is both in and out of the EU at the same time!
  8. as usual by fche · · Score: 0

    Insert here routine complaint that the federal government has no delegated power to fund or perform medical research.

    1. Re:as usual by Obfuscant · · Score: 3, Insightful

      Insert here "what could possibly go wrong with a single, national government database of DNA sequences ..."? "C'mon, you know it's the right thing to do..."

    2. Re:as usual by fche · · Score: 1

      yeah, that too!

    3. Re:as usual by silentcoder · · Score: 1

      The right would find a way to make pro-cancer sound like "freedom"... who would have thought.

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      Unicode killed the ASCII-art *
    4. Re:as usual by Shadow+IT+Ninja · · Score: 1

      It's not clear that they are talking about full DNA sequences. They will likely follow the Massachusetts rule of reporting only the differences between a cancer sample and the patients normal tissue. It's true that there are potentially important interactions between the mutations in cancer and the patients normal genetic variants but the most important thing is to know what changes caused the transformation to cancer. With a few exceptions, like BRCA1 and BRCA2, it's the mutations unique to the cancer which influence treatment decisions.

  9. Re:If Biden had won the Democratic nomination by bondsbw · · Score: 3, Insightful

    Off topic but I'll bite...

    If we had a better voting system, then the party primaries wouldn't really matter all that much. There would be no more voting for the person most likely to beat the guy you hate most on the other side. Instead of literally only having the choice of voting against HRC or Trump, we might actually get to choose a candidate we want.

    The problem isn't the candidates. It's the system that inevitably pits these awful candidates against each other as the only choice.

    http://www.cgpgrey.com/politic...

    --
    All my liberal friends think I'm a conservative, all my conservative friends think I'm a liberal.
  10. Biden useless? by Anonymous Coward · · Score: 0

    Spells potato with an E?

    About as useful as the VP who did.

  11. Why not? by Anonymous Coward · · Score: 0

    Why wouldn't they upload/share the info? For profits? You're saying someone smart enough to be a Dr. would rather see profits than save someone's life? And they say they aren't in it for the money...

  12. Classy DNA by PopeRatzo · · Score: 4, Funny

    When I'm president, we're going to have magnificent databases. The best databases, not loser databases like Biden's. Just tremendous, tremendous databases. We'll make Latvia pay for it, and there won't be any Mexican DNA in that database either, until we can figure out what's going on. We're going to have DNA that'll make your head spin.

    --
    You are welcome on my lawn.
  13. So how private are those patients' records? by Anonymous Coward · · Score: 1

    Seems like we just went through a widely-applauded act to block access to patient records in the name of privacy (HIPAA). National database of cancer patients -- what could possibly go wrong? (hint, the 'national database' of government employees' and contractors' clearance backgrounds, including financial information, criminal history if any, credit cards, etc. got breached last year, courtesy of Office of Personnel Management and their antiquated security measures). I think patient privacy was far better guaranteed before the push to convert all of it to digital media, 'in the name of confidentiality'.

  14. Never saw that coming by Anonymous Coward · · Score: 0

    I mean the government is actually trying to do something useful and help it's citizens. I believe this is the first time I have ever seen this from this administration. Usually they are targeting those evil white pedophile extreme racist nazis who believe they should be able to own their own land without government intervention, or those trying to sell cigarettes on the sidewalk without paying the extortion fees to the almighty house of Mammon.

    You could say they helped get some people out of jail, but I am sure with this administration they let out all the hard core pusher / gang-star types and kept the stupid harmless pot heads locked up for 40 years.

    This government makes money off of lottery (numbers racket), beer, alcohol, guns, kidnapping (highest incarceration rate in the world and CPS) etc. They are the real vice lords. The only people they actually protect are those who are invading the country illegally, and the major corporate donor types.

    Well, I have to give props for finally doing something that does not hurt the citizens of the USA. Good job Biden. I just wish you could have done more good and less harm.

    Say what you want about Putin, at least he is not actively trying to fuck his own people.

  15. Clearly Biden is being pushed for the presidency by roman_mir · · Score: 0

    Biden is clearly the establishment backup plan in case something happens to Clinton and she is indicted by the FBI for her illegal home made mail server used for government purposes.

    Trump is getting stabbed in the back quite a bit lately (not that he doesn't deserve all the stabbing).

    Bernie is a threat to the establishment that must be eliminated clearly.

    Personally I cheer for Gary Johnson, he has 10% of the vote already. Unfortunately there is no ancap candidate, but in a sense it would have been ironic to have one...

  16. Whatever Obama does by silentcoder · · Score: 2

    rightwingers rapidly assemble around the opposite - even for ideas they originally proposed.

    Mmm... *grabs popcorn*, I am looking forward to watching the republicans become pro-cancer. I can't imagine what the arguments will look like but I bet they'll include the phrase "will of God" at least 50 times.

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    Unicode killed the ASCII-art *
    1. Re:Whatever Obama does by silentcoder · · Score: 1

      And I found it... the horror of the federal government having a database of DNA... because spying on the dying is totally something they would care about, and somehow ignoring the fact that a federal database of DNA has been around for decades that IS actually used for law enforcement purposes and administered by the FBI.
      Oh but that once can't possibly be abused right, seeing as it was created under a republican administration. ... except that there was that major scandal last year when it turns out FBI techs have routinely committed perjury for years by massively inflating the probabilities from DNA tests in court. The great fear is already a reality, and it's already as bad as it gets. A database of cancer DNA won't change anything in that regard.

      Mind you, that same database has also been a major thorn in the side of government as well - the innocence project has relied on it extensively to get hundreds of wrongfully convicted death-row inmates released.

      Seriously if, you're going to find something to be tin-foil-hat about, find something which has not helped citizens against the government MORE than it is has helped government against the citizens.

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      Unicode killed the ASCII-art *
    2. Re:Whatever Obama does by DigiShaman · · Score: 1

      Asshole! You do realize that Joseph R. Biden III (his son) dies of brain cancer, right?! Despite the fact the current VP is a walking gaffe, joke, side-show bob; the death of his son forever changed him profoundly. No man should have to bare the weight of his son dyeing before his father out of an uncontrollable act of nature. If there's a silver lining in this event, is that future lives are saved through the collaborative effort of scientific discovery and progress. As always, it unfortunately it takes an act of death to push the impetus to save lives.

      FYI, while Ted Cruz would have gotten my vote, that now falls to Trump; and I will swim through lava to cast it over Clinton!

      --
      Life is not for the lazy.
    3. Re: Whatever Obama does by silentcoder · · Score: 1

      Why am I an asshole ? I support this idea. 8 supported it even though I had no knowledge of Biden's son dying of cancer ?
      I just know what the rabid right has been like and they already proved me right. The thread is filled with people declaring the horror of letting the federal government have a DNA database. Nevermind that they have had one for years.

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      Unicode killed the ASCII-art *
    4. Re: Whatever Obama does by Anonymous Coward · · Score: 0

      I hope someone you care about dies a horrible, slow death. I then hope you are killed in a painful and degrading way.

    5. Re: Whatever Obama does by DigiShaman · · Score: 1

      Why am I an asshole ?

      Because you took the opportunity to politicize one of the view items of research that's not a waste of tax dollars; which BTW is a very rare thing that congress does.

      --
      Life is not for the lazy.
  17. Re:If Biden had won the Democratic nomination by clickety6 · · Score: 1

    In a country of around 200,000,000 eligible candidates, to think that HRC and Trump are the best candidates that could be found is rather worrying...

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    ----------------------------------- My Other Sig Is Hilarious -----------------------------------
  18. What data? by Anonymous Coward · · Score: 0

    Since cancer cells are mutated body cells, does this database store the genome of patients with some mutated loci? Or does it only store the diff between a cancer cell and a normal body cell? What exactly are the privacy guards beyond anonymization?

  19. Re:If Biden had won the Democratic nomination by K.+S.+Kyosuke · · Score: 1

    Better implement A. C. Clarke's lottery, then?

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    Ezekiel 23:20
  20. Re:If Biden had won the Democratic nomination by CrimsonAvenger · · Score: 1

    If we had a better voting system, then the party primaries wouldn't really matter all that much.

    A couple of things:

    The Party primaries happened because too many people complained about the candidates from each Party being picked in "smoke-filled rooms" by Party bigwigs.

    So, the Party bigwigs pulled one of the biggest scams in history by convincing the States to pay for the primaries.

    Note that the Primaries, since they're entirely internal concerns of the Parties should NOT be paid for by the taxpayers, nor should people who are not Party members be involved in them (yes, open primaries are a very bad idea - it really helps when you can help select the candidate for the Party you don't belong to).

    As to choosing a candidate you want, maybe if more people actually tried voting for the candidate they wanted rather than voting against the candidate they dislike the most, we'd all be better off. Yes, voting Third Party probably won't get your guy elected (though it should be noted that the Republican Party was a "third Party" when they got that tall, skinny guy...what's his name? Link, or Lincoln, or something like that, elected. But you'll make the two major Parties take notice if a lot of people start voting Third Party - if nothing else, they'll have to adjust their policy positions to be nearer to that Third Party's positions, to try to pull voters back into the barn....

    --

    "I do not agree with what you say, but I will defend to the death your right to say it"
  21. Re:If Biden had won the Democratic nomination by bondsbw · · Score: 1

    As to choosing a candidate you want, maybe if more people actually tried voting for the candidate they wanted rather than voting against the candidate they dislike the most, we'd all be better off.

    Agreed, but the fact that this doesn't happen is a direct consequence of our voting system. It's something that probably couldn't change even if a majority of people want to change it, because plurality voting (first-past-the-post) inevitably ends in a two party system.

    The link I posted is a set of videos that outline the problems, and a potential solution or two (out of many possible solutions).

    --
    All my liberal friends think I'm a conservative, all my conservative friends think I'm a liberal.
  22. Standardization by Shadow+IT+Ninja · · Score: 1

    Actually, what might be more important than the database itself is the process of enforcing standards for how to describe a mutation. There is actually a standard set by the Human Genome Variation Society (HGVS) but it's not followed widely. In journal articles, different authors use different notation for the same mutation and, worse, often don't provide an complete specification. For example, it's common practice to report a mutation in terms of how it changes the protein which it codes for. However, many genes have alternate splicing, which means that there are different versions of the protein. A mutation might appear at a different position (or not at all) in the different versions of the protein.

  23. Re:If Biden had won the Democratic nomination by Obfuscant · · Score: 1

    Note that the Primaries, since they're entirely internal concerns of the Parties should NOT be paid for by the taxpayers,

    The voters are taxpayers. It's a vote dealing with elections of public officials. I think primaries being part of the normal voting processes is fine. There are almost always other things on the primary ballots, such as bond levies, school board elections, and initiatives, so the cost is pretty well sunk anyway.

    nor should people who are not Party members be involved in them (yes, open primaries are a very bad idea -

    I could not agree more.

    The "primary system" is not the cause of bad candidates. The cause is that being a politician has become a job with fewer positives than "used car salesman", and perhaps even "telemarketer". The absolute vitriol that appears during campaigns would deter anyone sane from running.