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Autism Starts Months Before Symptoms Appear, Study Shows (scientificamerican.com)

A new study published this week in the journal Nature suggests there is evidence of autism in the brain well before symptoms start to appear. Typically, the earliest that children are diagnosed with the disorder is at the age of two, although often times it is even later. Scientists may now be able to detect the disorder well before a child's first birthday via a magnetic resonance imaging (MRI) scan. Scientific American reports: Researchers conducted MRI scans on 150 children three times: at six months old, one year and two years. Just over 100 of the children were at high risk because they had an older sibling diagnosed with autism. The faster growth rate of the surface areas of their brains correctly predicted eight times out of 10 which of the high-risk children would go on to be diagnosed with the condition. Enlargement of the brain seemed to correlate with the arrival of symptoms, says Heather Hazlett, a psychologist at the University of North Carolina's Carolina Institute for Developmental Disabilities (CIDD), and the paper's lead author. Still, with only 100 at-risk children, the study is too small to be considered definitive -- nor should doctors rush to use MRIs to diagnose autism, Hazlett says. But if the study results are confirmed in future research, it could offer a new option for screening high-risk children before their symptoms become obvious -- and possibly at a time when treatment will be most effective.

119 comments

  1. Can't Be True! by ScentCone · · Score: 3, Insightful

    Because that might mean that autism is already setting in before certain Eeeeeevil vaccines have been given.

    Of course those government vaccines may have secret alien time travel substances which go back to start the autism before they are administered. That seems most likely.

    --
    Don't disappoint your bird dog. Go to the range.
    1. Re:Can't Be True! by Anonymous Coward · · Score: 0

      Citation, please.

    2. Re:Can't Be True! by Anonymous Coward · · Score: 1

      Seeing as how the parent poster pulled that 'fact' from their asshole, I'm not too sure you really want to request that citation.

    3. Re:Can't Be True! by JoshuaZ · · Score: 2

      It means that the vaccines are so bad that they are violating basic physics. Apparently vaccines can cause harm before they are even injected. Someone should talk to the physicists and let them know that the MMR vaccine contains tachyons.

    4. Re:Can't Be True! by quenda · · Score: 5, Funny

      vaccines may ... go back to start the autism before they are administered.

      Physicists have actually demonstrated this sort of thing is possible, using quantum entanglement contrary to common sense.

      You can actually have the past depend on the present, but the catch is that it cannot be used to transmit information back in time. Causality is not violated so long as the effects are not observed until after the cause.

      This is important: the very act of detecting autism with the MRI will break the quantum entanglement and stop the vaccine from causing autism.
      This may be a cure!

      (I hope there are still enough nerds on slashdot to appreciate this potential breakthrough.)

    5. Re:Can't Be True! by Anonymous Coward · · Score: 0

      All this means is that vaccines give the next generation autism, and you can't prove they don't! Or that it's those nasty nasty GMOs causing autism.

      Either way, science is out to get us again. Fortunately, on my website I sell a convenient detox cure made from all natural ingredients, only $39.95 for a two month supply. Your family's health may be at risk...you can't afford not to buy it!

    6. Re:Can't Be True! by Zaelath · · Score: 2

      There is no ACTUAL EVIDENCE. You're on the wrong site. Go away.

    7. Re:Can't Be True! by ShanghaiBill · · Score: 4, Informative

      There is no ACTUAL EVIDENCE.

      Indeed. There is no evidence, and even if there was evidence, it would be meaningless, because even the hypothesis is invalid. The hypothesis was that the mercury based preservatives ( thimerosal) in some vaccines caused autism. There were a few reports of a correlation. Those reports were discredited, and the researcher was accused of fraud and lost his medical license. But even if there was evidence (there is not), it wouldn't matter because mercury based vaccine preservatives are no longer used.

    8. Re: Can't Be True! by Anonymous Coward · · Score: 0

      Jenny Mccarthy, duh.

    9. Re:Can't Be True! by Anonymous Coward · · Score: 0
      There are also studies showing that the lack of vaccinations in the mother increases the risk of having an autistic baby. I'd find one for you, but you seem to like homework.

      So... Don't vaccinate your kids and they won't be autistic but their kids will be? Unless of course they get the regular you-are-born-with-it version of autism and not the definitely-came-from-the-vaccine mutant kind.

    10. Re:Can't Be True! by Anonymous Coward · · Score: 1

      Disregarding evidence based purely on an invalid hypothesis is bad science. Sometimes you may find evidence of something happening even though it's not what you were originally looking for. Let's say, hypothetically, that an overstimulated immune system at a young age might be able to trigger autism. If you are testing to see if the preservatives in the vaccine are triggering autism, and see a correlation, the hypothesis could be wrong but the evidence could still be useful.

      Disclaimer: I think the anti-vax movement is a load of nonsense. That doesn't excuse us from using bad science to discredit it.

    11. Re:Can't Be True! by Xabraxas · · Score: 1

      This is not true in any way. There are no known links. Stop spreading uninformed bullshit.

      --
      Time makes more converts than reason
    12. Re:Can't Be True! by Anonymous Coward · · Score: 0

      no there isn't you fuck wat twat cunt. go suck the dick of MR Wakfiled (yes that cunt twat lost his license for LYING about the link)

      you are too retarded to actually get what I am saying so get on with calling me a shill of big pharma and rich primary care physicians.....just walk right past the multi-million dollar homes of your heros like Sears and Tenpenny.

      Fuckwad.

    13. Re:Can't Be True! by Anonymous Coward · · Score: 0

      "we call that 'poisoning the herring' in public speaking. "

      I've never heard of that expression in my life. Ever. Please provide a citation that this is an English phrase for some sort of fallacy that you feel has occurred here.

      " There ARE links to vaccines causing autism."

      Should be easy to provide evidence.

      "Go do your homework, noob."

      CTRL-C, CTRL-V your evidence. That's all we ask of you.

    14. Re:Can't Be True! by Black+Parrot · · Score: 1

      Because that might mean that autism is already setting in before certain Eeeeeevil vaccines have been given.

      Maybe we can use this to predict who's going to get vaccinations?

      --
      Sheesh, evil *and* a jerk. -- Jade
    15. Re: Can't Be True! by Anonymous Coward · · Score: 0

      Dunno. I've had like 4 MMRs. Born in the eastern block when health records were on paper my parents managed to lose the book that had this listed in, so I got another one and a new book. Then the book was found. Then the army doctors shot me again when i entered the conscription pool. Then the US civil surgeon shot me again because he couldn't make heads or tails from my paper record. Still no autism

    16. Re:Can't Be True! by Anonymous Coward · · Score: 0

      BeauHD must have been over-vaxxinated.

    17. Re:Can't Be True! by mmell · · Score: 1

      There are also links that show marriage leads directly to divorce. 100% of all divorced couples were married first.

    18. Re: Can't Be True! by tbannist · · Score: 1

      The only "doctor" to have "evidence" of a link between any vaccine and autism lost his medical license because his evidence was fraudulent. Turns out, he never examined the patients in his "study", most of them didn't have autism, and he was being paid a shit-ton of money for the "evidence" by one of the competitors to the vaccine's he accused of causing autism.

      You have been played for a fool, but are too stupid to understand that.

      --
      Fanatically anti-fanatical
    19. Re:Can't Be True! by gweihir · · Score: 1

      Hey, why are you deriding the anti-vaxxers? They are just trying to make evolution work again (killing the stupid) and that is to be applauded, not ridiculed!

      --
      Most ACs are not even worth the keystrokes to insult them. Be generically insulted by this and ignored otherwise.
    20. Re:Can't Be True! by gweihir · · Score: 3, Informative

      There is exactly one study that deserves the name, and it was not only proven to be based on manipulated data, it did only prove it for one specific vaccine, because the author stood to profit form an alternate vaccine that was to come out soon and would not have the autism-risk. So even the original study, faked as it may have been, does not actually support the claims the anti-vaxxers are making! These people must be complete demented and functionally illiterate. Or probably just so deep in fear that they have no rationality left and are jumping at every shadow. Because there are no "facts" supporting the vaccine-autism link.

      Science says it is strongly genetic factors and some environmental factors like some infections during pregnancy, and use of alcohol or cocaine during pregnancy. Vaccination is not one of them and it has been looked into extremely carefully. Nothing there. But I guess even if medicine will eventually reliably be able to predict the condition well before any vaccinations are done, the anti-vaxxers will cling to their baseless beliefs.

      Oh, wait, there is one link: The mother _not_ getting vaccinated before pregnancy does increase the autism risk for children. So not only are the anti-vaxxers completely wrong, their mistaken belief actually makes the problem worse.

      --
      Most ACs are not even worth the keystrokes to insult them. Be generically insulted by this and ignored otherwise.
    21. Re:Can't Be True! by gweihir · · Score: 1

      Indeed. The whole idea is completely disconnected from reality. Not that these morons are the only ones. For example, a couple of billion people believe in some invisible man in the sky on "evidence" not any more solid.

      --
      Most ACs are not even worth the keystrokes to insult them. Be generically insulted by this and ignored otherwise.
    22. Re: Can't Be True! by gweihir · · Score: 1

      Some AC claiming obvious nonsense on Slashdot without citation is now "evidence that cannot be disputed"? Pathetic. Please take your alternate facts and stuff them.

      --
      Most ACs are not even worth the keystrokes to insult them. Be generically insulted by this and ignored otherwise.
    23. Re: Can't Be True! by gweihir · · Score: 2

      And it is even more: He was only "proving" that for one specific vaccine, because he wanted to promote another one without the risk that was to come out shortly (and earn him a pretty penny). So even the "original" faked study did not show what these morons think it did.

      --
      Most ACs are not even worth the keystrokes to insult them. Be generically insulted by this and ignored otherwise.
    24. Re:Can't Be True! by gweihir · · Score: 1

      Are you sure about that? I call "Fake News"! (Or is it "Alternate Facts"? I get confused by these modern terms for "lying blatantly"...) If you dig deep enough, you will find people that were divorced because of clerical error that never were married! That completely disproves your claim! Obviously your claims have no link to reality!

      --
      Most ACs are not even worth the keystrokes to insult them. Be generically insulted by this and ignored otherwise.
    25. Re:Can't Be True! by gweihir · · Score: 1

      Excellent! And think of all the other good this could do!

      --
      Most ACs are not even worth the keystrokes to insult them. Be generically insulted by this and ignored otherwise.
    26. Re: Can't Be True! by Plus1Entropy · · Score: 1

      I'd say "Pot, meet kettle.", but I think that would just involve you looking in the mirror.

      --
      Only crack the nuts that crack. You don't put the ones that don't crack in the sack.
    27. Re:Can't Be True! by omnichad · · Score: 1

      I don't think that's the only hypothesis still floating. There are a few hypotheses that autism may be autoimmune in nature, and caused by the immune response to one or more vaccines - where parts of the brain itself becomes a target of those antibodies.

    28. Re:Can't Be True! by Anonymous Coward · · Score: 0

      Also refer to The Endochronic Properties of Resublimated Thiotimoline Asimov. PhD., The timersol is also an endochronic organic chemical, and in keeping with well established Homeopathic Principals, The less timersol in the vaccine, the stonger the effect; Therefore modern vaccines are extremely endochronic because they have no timersol in them now.

    29. Re:Can't Be True! by Jason+Levine · · Score: 1

      That was just goal post shifting. Once the mercury link was busted, the anti-vax groups claimed it was other compounds in the vaccines. When that was disproved, they went to generic "toxins" or "they get so many vaccines that their immune system is overwhelmed." Never mind that they can't name the "toxin(s)" that cause autism (if they keep it generic, you can't disprove it) or that a baby's immune system wards off hundreds of bacteria/viruses daily (if not more) and a few shots won't tip the scales. They'll keep shifting the "why" in their belief that vaccines cause autism instead of admitting that they have nothing to do with one another.

      --
      My sci-fi novel, Ghost Thief, is now available from Amazon.com.
    30. Re:Can't Be True! by Jason+Levine · · Score: 1

      If this only affected their kids, I'd actually side with them and say vaccines should be a parent's choice. I'd still call not vaccinating the wrong choice, but it would be their choice. However, a parent who doesn't vaccinate their child weakens herd immunity and exposes other people to diseases. People who a) are too young to be vaccinated, b) can't be vaccinated for valid medical reasons, or c) were vaccinated but the vaccine didn't "take" (vaccines aren't 100% but herd immunity usually covers the fraction who don't get protected). When their actions negatively affect other people - including possibly killing them - they don't get to argue that it's their freedom to choose not to vaccinate and it goes beyond a "Darwin effect."

      --
      My sci-fi novel, Ghost Thief, is now available from Amazon.com.
    31. Re:Can't Be True! by Anonymous Coward · · Score: 0

      You're also making the assumption that immunizations overstimulate the immune system. Hidden assumptions like that can ruin science done with the best of intentions.

    32. Re:Can't Be True! by omnichad · · Score: 1

      That one goes back to at least 2000. Just because the anti-vax group latched onto it doesn't make the science any less.

      Not toxins, though - antibodies intended by the vaccine. Have a look at PANDAS for another as-yet unproven disease that may be caused by ordinary antibodies.

      And these predispositions would likely be genetic - clearly you wouldn't eliminate the causative vaccine. Rather, you would do genetic testing before vaccinating - and allow for a medical exemption in any laws written mandating vaccines. That is, if any link is ever definitively established.

    33. Re:Can't Be True! by Anonymous Coward · · Score: 0

      Here's MY citation... the government dont shell out money for something they dont think is they responsibility.
      http://www.huffingtonpost.com/david-kirby/post2468343_b_2468343.html

      or maybe they heard Jenny McCarthy and said "yeah screw it"

    34. Re:Can't Be True! by syntotic · · Score: 1

      Sorry, but it seems autism was redefined as... NOT HEARING VOICES. Which is NORMAL. It can be proven, argued. Next they will start saying the neocortex is a disease and language ability a nuisance: Guards! THAT MAN says he can COUNT!!!

    35. Re:Can't Be True! by Anonymous Coward · · Score: 0

      “What would happen if the autism gene was eliminated from the gene pool? You would have a bunch of people standing around in a cave, chatting and socializing and not getting anything done.”

        Temple Grandin, The Way I See It: A Personal Look at Autism & Asperger's

    36. Re: Can't Be True! by Anonymous Coward · · Score: 0

      Maybe they inherit the autism from their parents' vax.

    37. Re: Can't Be True! by Anonymous Coward · · Score: 0

      Everyone wants a definitive answer to the VAX => AUTISM debate. Suppose VAX increased the odds of autistic screeching by 10%, but no VAX increased the odds of a global pandemic by 5000%. Would science report the truth? Scientists can't reframicate w/o a jizz-ob....

  2. It's genetic by lazy+genes · · Score: 0

    Everyone in my town suffers from some form of autism. It's more obvious late in the winter.

  3. FAKE NEWS by DonaId+Trump · · Score: 4, Funny

    Believe me, folks, this study by so-called "scientists" is dead wrong. Anyone with a brain knows vaccines are what cause autism. I refused to have Barron vaccinated and look, he's the best at cyber, he's a huge cyber, he's going to be running the whitehouse.ru website.

    1. Re: FAKE NEWS by Anonymous Coward · · Score: 0

      Big league! Make the Apocalypse Great Again!

    2. Re:FAKE NEWS by RockDoctor · · Score: 1

      he's going to be running the whitehouse.ru website.

      Oh - Rule 34 alert! Whether or not it's a pr0n site, let alone a "tiny hands and hard sports" site, I don't know. But I'm seeing that domain linked to two addresses in 90.156.201.xxx

      No idea who is cybersquatting on it, but props for forethought and planning.

      --
      Birds are not dinosaur descendants;birds are dinosaurs, for all useful meanings of "birds", "are" and "dinosaurs"
  4. Of course it does!!! by NeoStrider · · Score: 1

    You're kidding... really? I always thought that it didn't exist until the doctor told you that you had it... so they're tell us now that we all could just be undiagnosed. Noted!

    1. Re:Of course it does!!! by mmell · · Score: 1

      It does explain the current POTUS pretty well, doesn't it? No social or interpersonal skills to speak of, doesn't work or play well with others . . . a shame it wasn't caught when he was young.

  5. everything starts before symptoms appear by turkeydance · · Score: 4, Insightful

    even by a little bit

    1. Re:everything starts before symptoms appear by Anonymous Coward · · Score: 0

      Yet another brain-dead /. headline.

      The actual article is about how they can detect autism before symptoms start.

    2. Re:everything starts before symptoms appear by ShanghaiBill · · Score: 2

      The actual article is about how they can detect autism before symptoms start.

      That could already be done. Autism can be predicted by extracting stem cells, and prompting them to grow into little bundles of nerve cells. If each neuron has fewer than a normal number of connections, that person is predisposed to develop autism. A higher than normal number of neural connections correlates with Williams Syndrome, which is sort of "inverse-autism", with a high level of empathy and social engagement, but an astonishing inability to reason quantitatively.

    3. Re: everything starts before symptoms appear by Anonymous Coward · · Score: 0

      Dunno, back where I come from everything can be solved with one of two universal cures - for a small problem: calmth, goodness, a little beating or for a big problem: beating, fucking and Serbian music. Kids are regularly subject of corporal discipline - babies are slapped if they cry of if they don't want to eat, or if they don't listen and do what they are told. Autism is non-existent.

    4. Re:everything starts before symptoms appear by Anonymous Coward · · Score: 1

      This article says the autistic brains are bigger and therefore I assume have more neural connections. Autism is an evolutionary advance and the neurotypicals are too stupid and backward to see it.

    5. Re:everything starts before symptoms appear by Anonymous Coward · · Score: 0

      Thank you, Greg Bear, but your prediction of rapid evolution occurring within the next 50-100 years just isn't happening.

    6. Re:everything starts before symptoms appear by ShanghaiBill · · Score: 1

      This article says the autistic brains are bigger and therefore I assume have more neural connections.

      I don't see any reason to assume that. Autism is correlated with fewer connections per neuron, so there could still be more total neurons. There is also a lot of white matter in brains that can add a lot of volume without adding to the number of connections.

    7. Re: everything starts before symptoms appear by Anonymous Coward · · Score: 0

      There's an even easier way: nerdy dad OR mom == 25%-50% chance of aspie child.

      Nerdy dad AND mom == 25% chance of hardcore, classic autism, 50% chance of aspergers, 25% chance of neither.

      Autism is genetic. It's evolution's circuit breaker for keeping smart people from having TOO MANY smart kids and breeding dumb kids out of existence.

      A few smart people enrich society. Too many smart people, and society becomes dysfunctional.

      Evidence: the autism rate is WAY higher among couples who are both highly-educated & smart. Though arguably, the most genetically-toxic combo seems to be aspie dad + artsy empath wife... you get kids mentally wired for autism, but with Jungian cognitive functions that prefer feeling & sensing over thinking & intuition. The result is a kid who's kind of like a TI-99/4a... internally-conflicted from birth, with extraordinarily buggy hardware compounded by inappropriate software.

    8. Re:everything starts before symptoms appear by globaljustin · · Score: 1

      Autism is an evolutionary advance

      hmm...I'd give you "competitive advantage in some cases" but "evolutionary advance"...

      evolutionary advances are not seen on 100 year timescales

      also, whatever change must increase the ability to reproduce for it to be related to evolution

      --
      Thank you Dave Raggett
    9. Re:everything starts before symptoms appear by apoc.famine · · Score: 1

      I think fractured bones may push this statement to its breaking point.

      --
      Velociraptor = Distiraptor / Timeraptor
    10. Re: everything starts before symptoms appear by Anonymous Coward · · Score: 0

      autistic screeching is actually a clarion call to the alien geneticists that invented us, like that big black box on that space movie by that unkempt guy with the beard.

  6. As An Autistic Adult Planning To Have Children, by Anonymous Coward · · Score: 0

    Nevermind.

  7. This is news? by Egg+Sniper · · Score: 1

    Though autism probably isn't one consistent, monolithic thing, it's long been suspected that one's autistic fate is potentially sealed before birth. A quick search yields: https://www.ncbi.nlm.nih.gov/p...

    1. Re:This is news? by Anonymous Coward · · Score: 0

      Yeah, the title seems pretty lousy on this -- it seems (?) to me that the actually interesting fact is that there are physiological markers that can be detected well before conventional diagnosis methods would work. So it seems that "autism starts months before" would be better phrased as, "autism can be detected months before."

      AC as I modded.

    2. Re:This is news? by omnichad · · Score: 1

      Or more accurately, symptoms can't be detected until months after.

  8. Not likely to help diagnosis by Chalnoth · · Score: 1

    Autism has a prevalence of (very roughly) 2%. If the MRI test falsely diagnoses children without autism as being autistic 20% of the time, then roughly 90% of all people who test positive will not be autistic. You might be able to get a little bit better by only screening at-risk children (e.g. family history of autism), but this is still going to be wildly inaccurate and what would even be the point? It's not like parents have to do anything differently until the symptoms of autism present themselves.

    But it is nice to see more evidence that autism is in evidence long before symptoms appear, because it makes nonsense of many of the claims of bullshit artists that vaccines cause autism.

    1. Re:Not likely to help diagnosis by BigDukeSix · · Score: 3, Informative

      With respect, you have missed the point (completely). This isn't about finding a screening test. This is an objective, likely quantitative readout from a standard imaging study that can be used as an endpoint in clinical trials. Most clinical trials in this area fail because they use some sort of subjective behavioral scoring system, rather than a quantity that can be measured (with a very expensive ruler) from the patient. And ... 2% of the population? That's a fucking wet dream for a big pharmaceutical company. This finding has the potential to take autism from the realm of voodoo into a treatable clinical entity.

    2. Re:Not likely to help diagnosis by ceoyoyo · · Score: 1

      It doesn't usually work like that. The FDA is (quite rightly) suspicious of putative surrogate measures in clinical trials. It takes a lot of work to actually get something like an imaging metric accepted as a surrogate and validated as a primary outcome, and very few have been.

      This study provides clues about what exactly autism is and when it starts. Its interesting scientifically, and having something you can image will help immensely for scientific studies, just as you describe.

    3. Re:Not likely to help diagnosis by gweihir · · Score: 1

      And that was no the point, at least not directly. It is just one more piece of the puzzle, and it means you can start firming up a diagnosis way earlier. Of course you cannot use a single test that has a high probability of error, but it helps as part of a set of tests. Statistics 101.

      --
      Most ACs are not even worth the keystrokes to insult them. Be generically insulted by this and ignored otherwise.
    4. Re:Not likely to help diagnosis by ckatko · · Score: 1

      Imagine all the healthy babies aborted because they thought they had autism.

    5. Re:Not likely to help diagnosis by wagnerrp · · Score: 1

      If the MRI test falsely diagnoses children without autism as being autistic 20% of the time, then roughly 90% of all people who test positive will not be autistic.

      According to the abstract, only 12% of those tested positive were not later diagnosed as autistic. You're just making argument over nonsense numbers, when the real numbers are available.

    6. Re:Not likely to help diagnosis by RandyHill · · Score: 1

      There is no such thing as "autism", there is a number of different behaviors on the autistic spectrum. The study references the spectrum, but I'm not going to spend $32 to find out which behaviors they correlated with.

      Example: My daughter was diagnosed as Autistic at age 3 & 1/2, she was given a 13 point test by a psychologist, and she scored over on 7 of the tests (I think scoring over on 6 is considered autistic), but she was barely over on those. She was given the test because her vocabulary had started to decline precipitously once she turned three. She's had 5 years of ABA therapy, was in special ed until mainstreaming in 3rd grade, and now making the honor roll in 4th.

      I always felt she had a good opportunity to recover, given that she only evidenced about half the behaviors and didn't measure highly autistic on any of the behaviors she evidenced. Would this test have detected her autism, or would it not be severe enough? Would it detect autism in kids who later only evidence 3 or 4 of the traits? False positives is a big issue, because parents can get crazy about this stuff.

    7. Re:Not likely to help diagnosis by RandyHill · · Score: 1

      You both aren't understanding the abstract. The abstract says it has a "positive predictive value" of 81%, that's the number of diagnoses that turn out to be true. Sensitivity was 88%, that's the percent of autistic kids detected by the test.

      So if a population has 2% autistic rate, and you ran this test on 1,000 children, 20 kids will later turn out to be autistic, and a Sensitivity rate of 88% says that somewhere between 17 and 18 will have been detected by the test. The positive prediction value says that for every 4 correctly identified as autistic, slightly more than 1 child will be falsely identified as autistic, in 1,000 kid example that means around 5 falsely identified.

      As I said elsewhere, autism isn't really a thing, it's actually autism spectrum disorders, and it's a range of behaviors. My daughter was diagnosed with 7 out of 13 behaviors and was barely into the autistic scale on the behaviors she evidenced. Still it was enough for her to have lost most of her social skills in less than a year. The question is what spectrum disorders is this test predicting and how accurately for each one?

  9. Superpowers by Anonymous Coward · · Score: 0

    The faster growth rate of the surface areas of their brains

    Sounds like a beginning of a superpower.

  10. Treatment by manu0601 · · Score: 1

    It is nice to diagnose, but without treatment, what will the outcome be?

    1. Re:Treatment by Anonymous Coward · · Score: 0

      The treatment is not allowing women with hormonal issues to have children.

    2. Re:Treatment by Xabraxas · · Score: 1

      Older men also have a higher incidence of Autism in their offspring so that means you have to limit men as well.

      --
      Time makes more converts than reason
    3. Re: Treatment by Anonymous Coward · · Score: 0

      Mankind would become extinct with that prohibition.

    4. Re: Treatment by Anonymous Coward · · Score: 0

      Exactly what treatment is the OP tolkning about? Is there any treatment at all?

    5. Re:Treatment by Whatsisname · · Score: 1

      Science moves one step at a time.

    6. Re: Treatment by manu0601 · · Score: 1

      Is there any treatment at all?

      There is a flavor of autism called "regressive autism" with symptoms that disapear with gluten and casein eviction. Apart than that I am not aware of any treatment.

    7. Re: Treatment by sound+vision · · Score: 1

      Diagnosis is a treatment in itself for this type of thing. The earlier and more certainly parents recognize this is a neurological issue and not just behavioral (or a result of vaccines, demonic possession, etc.) the less likely they are to treat their kids in a way that fucks them up further.

    8. Re: Treatment by RandyHill · · Score: 1

      yea, the gluten and casein eviction stuff is just nonsense, it's just another in autism's long history of quack treatments.

      What has been proven to work is ABA therapy and it's derivatives. But it's not a panacea, it's track record is about 50-50 on curing kids. My daughter was diagnosed at three and a half years, and after 5 years of ABA therapy she was mainstreamed in school and made the honor roll. We were able to discontinue therapy as she is pretty much normal now (though still quirky).

  11. No, Autism starts before symptoms are OBVIOUS. by Anonymous Coward · · Score: 0

    This article does make sense though. An autistic 2 year old WAS an autistic 1 year old who WAS an autistic 6 month old.

    It is a developmental disorder, not a goddamn infectious disease. Of COURSE there are subtle findings before things are grossly abnormal.

    I worked with a developmental specialist who would request families bring in movies of their child, including as many from as early in life as possible to both help confirm the diagnosis, assess the degree of dysfunction, and to SHOW THE FAMILIES THIS ISN'T NEW. Behaviors that they wrote off as quirks were actually early abnormal developmental findings. Their child, as much as they love them and may want this to not be true, has had problems leading to this point for quite a while, but that's ok because now they're getting help.

    But it's cool that you can get MRI's to look for findings, I guess. Maybe something will come of this. 80% ain't great, though.

    1. Re:No, Autism starts before symptoms are OBVIOUS. by gweihir · · Score: 1

      80% ain't great, though.

      It is something else you can use to get the reliability of the diagnosis up when you have a suspicion. And it helps understanding the process better, because it means you can study it earlier because there is a way to identify children that are reasonably likely to develop the condition. All in all a pretty good and helpful scientific result.

      --
      Most ACs are not even worth the keystrokes to insult them. Be generically insulted by this and ignored otherwise.
    2. Re:No, Autism starts before symptoms are OBVIOUS. by Anonymous Coward · · Score: 0

      My grandfather had dementia, and after we accepted that, we could see a pattern of behavior stretching back for a decade prior to it becoming obvious.

  12. Re:The Autistic Problem by Xabraxas · · Score: 1

    You sound like a horrible human being that would get hit by a bus tomorrow if karma existed.

    --
    Time makes more converts than reason
  13. Enlargement of the brain seemed to correlate... by fustakrakich · · Score: 1

    Sounds like a good time to bring back trepanation

    --
    “He’s not deformed, he’s just drunk!”
  14. Re:The Autistic Problem by Anonymous Coward · · Score: 0

    Hmm. Euthanize? Might be a little more than needed.

    We need specialized institutions to house these unfortunate people, somewhere where they can exist without causing problems for others. Their parents can pay for them based on a sliding scale based on ability to pay. This will provide help for their kids without draining the treasury.

  15. bitztream by Anonymous Coward · · Score: 1

    bitztream claims he can detect autism just by looking at the parents in 3..... 2..... 1.....

  16. Re: The Autistic Problem by Anonymous Coward · · Score: 0

    Hmm. You all realize that the autism spectrum ranges from mild to severe ... right? You can't make blanket statements about something that probably at least 80% of people on the spectrum understand better than you. There's a population of highly successful people on the spectrum that live rich, fullfilling lives, including MYSELF.

    So, in conclusion ... please get educated before spouting sensless bullshit or kindly go fuck yourselves with a rusty claw hammer.

    Now, if you'll all excuse me, I need to get some rest, so I can be bright and fresh tomorrow for my six figure salary engineering job. Gotta live up to those glowing performance reviews that I get, annually.

  17. Salon: The Monster Inside My Son by Anonymous Coward · · Score: 1

    Salon has a great article on autism: The Monster Inside My Son!

    Scary stuff. The stuff of horror movies.

    1. Re:Salon: The Monster Inside My Son by Anonymous Coward · · Score: 0

      Amazing read

    2. Re:Salon: The Monster Inside My Son by Anonymous Coward · · Score: 0

      Looks like the author of the Salon article happens to have a kid who is both autistic and psychopathic. The problem she's seeing is the kid's psychopathy, not his autism. There are millions of non-psychopathic autistic counterexamples.

  18. Re: Evidence by hackwrench · · Score: 2

    Without a citation there is no indication that the evidence exists. And no you can't just Google it, because there are too many invalid results.

  19. Re:Arrow of time by hackwrench · · Score: 1

    The arrow of time is an illusion and if you make a video of atomic level events and play it forwards and then play it backwards, no one can tell you which is which.

  20. Re: The Autistic Problem by hackwrench · · Score: 1

    Oh come on, everybody knows you just have to find the right autistic person for the job. Sure they like to overspecialize, but that just means that not just any one will do.

  21. Re:The Autistic Problem by Anonymous Coward · · Score: 1

    Just so. Autistic people don't do dishonest manipulative passive aggression. Autistic people do actual aggression. People who work well on certain tasks need to be treated as specialists and not assigned tasks outside of their specialty. As a manager you need to recognize that you can't assign random tasks to random people and expect people to respond to your capricious demands like interchangeable fleshbots. The problem is your utter lack of ability to manage properly the talents of the people working for you.

  22. Re:The Autistic Problem by hackwrench · · Score: 1

    Ah, but you underestimate the power of the people who get their jollies from causing problems for others, for whom the autistic people are a valuable resource.

  23. Re:The Autistic Problem by Anonymous Coward · · Score: 0

    I am surprised any of your relatives talk to you long enough to ask you for a favour; you sound like a complete fucktard without whom the world would be an ever so slightly better place.

  24. Re:The Autistic Problem by Anonymous Coward · · Score: 0

    You're the one who sounds insane, bro. Trying to describe an autistic kid, I think you just described your psychopathic boss self, jack. Can you say "projection"?

  25. Re:The Autistic Problem by globaljustin · · Score: 1

    These retards should have been aborted or smothered in their cradle.

    heh...wrong

    they need help to specialize in the right situation

    --
    Thank you Dave Raggett
  26. Re:Arrow of time by phantomfive · · Score: 1

    But at a higher level it's easy to see which direction time is moving. Why is that?

    --
    "First they came for the slanderers and i said nothing."
  27. Re:Arrow of time by gweihir · · Score: 1

    The best explanation we have is that the observer makes this happen. Hence without observer, both possible directions for time are valid. It is unclear how sophisticated the observer has to be, but a machine will not do.

    --
    Most ACs are not even worth the keystrokes to insult them. Be generically insulted by this and ignored otherwise.
  28. Re:Arrow of time by phantomfive · · Score: 1

    heh.........so if a tree falls in a forest and no one is around, does it still make a sound? Or does it 'fall' up?

    --
    "First they came for the slanderers and i said nothing."
  29. What year is it? by Anonymous Coward · · Score: 0

    Why are you advocating Victorian Era social programs to address mental illness?

  30. Re:Arrow of time by Place+a+name+here · · Score: 1

    I'd imagine the most likely explanation to be that the statistical probability of event x happening in the future given that y has happened in the past is not the same as the probability of y happening in the future given that x happened in the past; but at very small scales, the difference is too small to see at any small time delta.

    If so, try speeding up the video or yes, look at a higher level.

  31. Re:Arrow of time by JonnyCalcutta · · Score: 1

    'crash' si sekam ti esion eht ,seY

  32. Re:Arrow of time by Plus1Entropy · · Score: 1

    Primarily due to the Second Law of Thermodynamics. Events which increase entropy are vastly more likely than those that decrease entropy. So the Universe tends towards higher entropy. When the Universe reaches maximum entropy, i.e. heat death, no more change can occur, and time stops.

    The best analogy I've heard (stolen from a documentary I don't remember the name of), is to think of a sand castle. In a sand castle, the grains of sand are highly ordered into a very specific shape and structure. We can consider this as a state of low entropy. Any disturbance of this order, due to wind, the tide, someone stepping on it, etc., increases the disorder of the sand castle, reducing it ultimately to a pile of sand.

    The pile of sand is our state of high entropy. It's very difficult to increase the disorder of the pile of sand: no matter how much you mix it up, it will largely remain a pile of sand.

    There is nothing fundamental to the laws of physics that prevents the perfect combination of wind to come along and blow a pile of sand into the shape of a sand castle. But obviously such an event is incredibly unlikely, compared to all the ways the sand can be reduced back to a pile.

    Of course, it is possible to reduce the entropy of a system locally, but this requires external energy to be introduced, which will lead to a net increase in the Universe. Consider how much energy you have to expend to construct a sand castle, versus how much energy it would take some asshole to come along and kick it down.

    I guess what I'm saying is, building sandcastles is a waste of time.

    --
    Only crack the nuts that crack. You don't put the ones that don't crack in the sack.
  33. Age of Parents Correlates Heavily with Autism Rate by DatbeDank · · Score: 1

    The rise in autism correlates heavily with geriatric parents (ie men and women who have children after 35). There was a study done that highlighted such a correlation. Posting on mobile, otherwise i'd link directly to one.

  34. But ... by Gription · · Score: 1

    Disregarding evidence because of an invalid hypothesis isn't an issue. Unless you have a hypothesis it isn't science. A hypothesis is required.

    So toss out any invalid hypothesis and any "evidence" isn't evidence until you get a new hypothesis to test.
    Science.

  35. So it's not vaccines after all by Anonymous Coward · · Score: 0

    So it's not vaccines after all (which we all knew). It's the hormones we're pumping our kids full of because we can't stand the idea of including enough vegetables in our diet to avoid having to eat 200 lbs of meat every year. Yep, the average American eats more than their bodyweight in meat every year. And, that meat is full of hormones, antibiotics, and pesticides. At least vegetables are only full of pesticides.

    It just so happens that the rise in autism also correlates temporally with the advent of mass agricultural hormone use in the 1980s. Chickens, Cows, Hogs, basically any food animal, is pumped full of enormous amounts of hormones so they grow more quickly and don't cost as much to raise for slaughter. Expecting moms who have eaten meat their whole lives give milk that is also tainted. It's sickening that we're pumping infants full of the same hormones.

  36. Re:Arrow of time by lifeisshort · · Score: 1

    So this https://uk.pinterest.com/rupert55/sand-art/ guy is basically wasting his time?

  37. Re:Age of Parents Correlates Heavily with Autism R by Hognoxious · · Score: 1

    Correlation is not causation. It's equally possible that thirty years ago parents at that age were the exception and aspies were regarded as nutters and just sent to play away from the normal kids.

    --
    Confucius say, "Find worm in apple - bad. Find half a worm - worse."
  38. Re:Arrow of time by gweihir · · Score: 1

    Wrong question. The right question is whether a tree _can_ fall when nobody is around...

    --
    Most ACs are not even worth the keystrokes to insult them. Be generically insulted by this and ignored otherwise.
  39. Re:Arrow of time by quenda · · Score: 1

    The arrow of time is an illusion

    All our perceptions are simplifications - e.g. solid matter. An "illusion" is more like the opposite: seeing complexity when reality is simpler.

     

    make a video of atomic level events and play it forwards and then play it backwards, no one can tell you which is which.

    Doesn't entropy still apply at the atomic level. e.g. particle decay?
    Sure the maths (classical mechanics or wave function?) works both ways, but one is far more probable than the other.
    If I see a barium and krypton nucleus collide and fuse into a stationary U235 nucleus, you will not be able to persuade me that the film is not running backward.

  40. Unique Nature of webapps by rrajdev · · Score: 0
  41. Re: The Autistic Problem by Anonymous Coward · · Score: 0

    Thermopylae-era Persia was actually a significantly more civilized place than Sparta; ignoring the child murder you seem to okay, Sparta incorporated a slave caste, the helots, composed of all the residents of conquered neighboring territories. They vastly outnumbered the Spartans, so the Spartans used extreme brutality to maintain fear/control, including what amounts to annual "murder the slaves" celebrations and a force of "secret police" that existed to keep them terrified and servile. There was no real hope of joining the Spartan citizen class; citizenship required an education that was only offered routinely to those with direct bloodline links to the founding bloodlines of Sparta. The Spartans forbade themselves to engage in any economically productive activity, relying entirely on their slaves and non-citizen "freemen" to provide all the labor and trade needed to support their wholly military society.

    By contrast, the Persians of the time banned slavery (there may have been some exceptions involving sale of conquered/rebellious armies, but there was no enslavement of common workers). They had an artistic culture at least as rich as Sparta's (Sparta's artistic culture is generally undersold, but Persia was incredibly rich). They invented the very first postal system, an official coinage based monetary system (adopted from a conquered Turkish kingdom), practiced a dualistic religion (Zoroastrianism, a precursor to modern monotheistic religions), but practiced tolerance of other religions. They were not savages.

    But lets say you want to defend the Spartans on the basis of Athens, which they "defended". Well, first off, Athens instigated the war by encouraging revolts by regions within the existing Persian Empire, Persia's invasion was arguably a response to the meddling in their internal affairs. Secondly, those 300 you refer to were actually 300 Spartans plus 7000+ troops (3000 of them were conscripted from the Spartan non-citizen caste, the rest from all over Greece); the rearguard action was 300 Spartans + 1200 allied troops; in both cases, the Spartans were a minority of the defenders. And a wholly non-Spartan (Athenian led) naval fleet was the only reason the Battle of Thermopylae even mattered (the Spartans had minimal naval defenses, so outflanking them by ship would have been easy. The fleet held out longer than the Spartans did, withdrawing when Thermopylae was reported lost.

    And even if we accept that Sparta "saved" western civilization (as exemplified by Athens), it took them less than 50 years to begin the Peloponnesian War, in which Athens was eventually defeated, their defenses, government and empire destroyed, a Spartan puppet government, the "Thirty Tyrants", was installed, and the economy of all Greece reduced to shambles. The in-fighting weakened all parties so much that the Macedonians (who had actually supported the Persians when they invaded Greece at the time of Thermopylae) were able to conquer the peninsula a few decades later.

    Short version: The Spartans were terrible, the Persians were no savages, and your whole argument is null and void.

  42. To all you worthless pieces of shit out there by beastofburdon · · Score: 1

    How the hell can you claim that vaccines have no link to autism when not a single vaccine in history has been tested against a placebo?
    If you want to argue this fact show me one single study which used an actual placebo, not the adjuvant without the rest, an actual placebo.

  43. Re:Arrow of time by RespekMyAthorati · · Score: 1

    It is unclear how sophisticated the observer has to be, but a machine will not do.

    Horseshit.
    In physics, an "observer" is just something that causes waveform collapse.
    Anything that absorbs energy at the given wavelength will do.
    It could be a person, a machine or a lump of coal.

    God, gweihir, you and your fantasy science.

  44. Re:Arrow of time by RespekMyAthorati · · Score: 1

    Well said.