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Bill Gates Pledges $100 Million To Find an Alzheimer's Cure, His First Commitment To a Non-communicable Disease (reuters.com)

At present, there is no treatment to stop the Alzheimer's. Bill Gates wants to make a sizeable attempt to change that. From a report:He is to invest $50 million in the Dementia Discovery Fund, a venture capital fund that brings together industry and government to seek treatments for the brain-wasting disease. The investment -- a personal one and not part of Gates' philanthropic Bill & Melinda Gates Foundation -- will be followed by another $50 million in start-up ventures working in Alzheimer's research, Gates said. "It's a huge problem, a growing problem, and the scale of the tragedy -- even for the people who stay alive -- is very high," he said. Despite decades of scientific research, there is no treatment that can slow the progression of Alzheimer's. Current drugs can do no more than ease some of the symptoms.

22 of 135 comments (clear)

  1. Good Work Billy Boy!!!!! by Anonymous Coward · · Score: 3, Insightful

    I'm sure this thread will be filled with pithy comments and shit-talking but at the of the day, I give the guy a lot of credit for dumping money into real-world problems.

    1. Re: Good Work Billy Boy!!!!! by Mkkby · · Score: 2

      Science is often bogged down by dogma. If he funds different approaches it might bear fruit. If he takes the lazy approach and asks the "experts", the money will most likely be wasted.

  2. There will never be a cure... by Kenja · · Score: 3, Informative

    Once you're brain is full of holes, that's more or less it. There can however be preventative treatments.

    --

    "Have you ever thought about just turning off the TV, sitting down with your kids, and hitting them?"
    1. Re:There will never be a cure... by Dan+East · · Score: 5, Informative

      As usual the summary isn't quite accurate. "Curing" the disease, as in reversing it once it has damaged a person's brain, is not the actual goal. From the article (emphasis mine):

      Through talking to experts in the field over the past year, Gates said he had identified five areas of need: Understanding better how Alzheimer’s unfolds, detecting and diagnosing it earlier, pursuing multiple approaches to trying to halt the disease , making it easier for people to take part in clinical trials of potential new medicines, and using data better.

      --
      Better known as 318230.
    2. Re:There will never be a cure... by serviscope_minor · · Score: 2

      Once you're brain is full of holes, that's more or less it. There can however be preventative treatments.

      True but you don't start with your brain full of holes. It starts with a very few holes and slowly becomes full. Once your brain is mush, there is nothing left to reover. However, halting it in the very early stages would be a reasonable thing to do.

      --
      SJW n. One who posts facts.
    3. Re:There will never be a cure... by PCM2 · · Score: 3, Informative

      Once you're brain is full of holes, that's more or less it. There can however be preventative treatments.

      Pedantic chime-in to say that "a brain full of holes" is more descriptive of spongiform encephalopathies, such as Creutzfeldt-Jakob disease. Alzheimer's is more like having a brain full of gunk.

      --
      Breakfast served all day!
  3. Re:How much has Linus contributed? by DontBeAMoran · · Score: 4, Insightful

    Linus doesn't have the profits of decades of back-stabbing, under-handed shady deals with multinational corporations that Bill Gates has.

    --
    #DeleteFacebook
  4. Re: what a loser by Anonymous Coward · · Score: 5, Insightful

    Do you know how much stress is involved in a young person seeing their parents go through Alzheimer's? If so then this would directly affect the well-being of the young.

  5. Re: what a loser by idji · · Score: 4, Insightful

    So what you should we do with you when you are demented? Let young people look after you? Turn you off? Itâ(TM)s not an old person issue - it affects everyone.

  6. Feeling old, Mr. Gates? by Anonymous Coward · · Score: 4, Insightful

    It's astounding how many tech billionaires see their calling in prolonging life.

  7. Re:what a loser by amalcolm · · Score: 4, Insightful

    As someone who has had to watch a close relative become a stranger before my eyes, I think you are talking shit. It's not just about the person, but those around them that suffer too. If Gates' money has produced no results and I'm struck by this horrible disease, I hope someone will put me to sleep.

    --
    Time for bed, said Zebedee - boing
  8. should be -- ESPECIALLY for by bill.pev · · Score: 2

    -- even for the people who stay alive -- S/B --ESPECIALLY for
    This online community relies on its brain over our hands or bodies to an unusual degree. Losing mental capacity sucks, even the natural aging stuff. [five of you know what I mean.] Alzheimer's is living death.

    But starting a VC fund to fund research rather than funding NFP research organizations is a model for guiding the invisible hand in the era of small government. It's not new, but its worth mentioning. This is not a part of the charitable foundation. This is funding formerly charitable work outside the charity. Kinda sounds "for profit" to me.

  9. For young and old [Re:what a loser] by Geoffrey.landis · · Score: 5, Insightful

    I assume you're being deliberately provocative, which is to say, you seem to be trolling for an intemperate response.

    OK. You're wrong.

    First: "Young people need a better future." Yes, and here's what's in the future of young people: they're going to become old people. Young people damn well do want an end to Alzheimers, because without one, it's in their future.

    Second, caring for elder people who have Alzheimers is a huge drain on the younger people who have to do the caring, and it's a drain emotionally, physically, and financially. You really do not want to put your parents into an Alzheimer-care assisted living facility and watch them slowly deteriorate on the long road to dying. Trust me.

    And third, it's not a dichotomy. Working on stopping one disease doesn't mean that you can't also work on making the world better in other ways as well; and understanding of biology learned from working on Alzheimers may very well have benefits to other diseases and brain injuries, some of which may very well also strike young people.

    So, summary: no. Learning to stop Alzheimers would be a good thing for all of us, including old and young people.

    --
    http://www.geoffreylandis.com
  10. Venture capital fund - Is this another investment? by Anonymous Coward · · Score: 5, Interesting

    A lot of Bill's philanthropy is actually for-profit investments. A treatment for preventing Alzheimer's could be very profitable, so this may turn out to be a lucrative investment if it pays off.

    That's not to say there's anything wrong with Bill's approach. Giving people money with no strings attached generally results in that money being wasted (see: the government). I think Bill's more commercial approach to philanthropy has a far better chance of delivering results.

  11. Bill would pledge, but by Tablizer · · Score: 2

    ...he forgot where he put the check.

  12. Re:Venture capital fund - Is this another investme by Geoffrey.landis · · Score: 5, Interesting

    Giving people money with no strings attached generally results in that money being wasted (see: the government). I think Bill's more commercial approach to philanthropy has a far better chance of delivering results.

    That's a very libertarian sentiment, but it's sometimes true and sometimes not.

    I am happy to live in the twenty-first century, and one of the things about our time that I am most proud of is that I live in a world in which smallpox does not exist as a disease. It was wiped out. It was wiped out by a deliberate, concerted campaign by the World Health Organization, by doctors who really had nothing personal to gain by eliminating smallpox from villages in the third world that they would never visit.

    (On television, the planet has been saved by the actions of Doctor Who. For much of the planet, however, the real work in saving the planet was actions of the WHO doctors.)

    --
    http://www.geoffreylandis.com
  13. Re:There will never be a complete brain. by Opportunist · · Score: 4, Funny

    Yes, but that solution doesn't really scale well, we only need one president.

    --
    We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
  14. Re:Venture capital fund - Is this another investme by GLMDesigns · · Score: 2

    The argument is NOT that companies aren't wasteful.

    The argument is that as companies waste more and more money; as they become more and more inefficient they become less profitable and less competitive. Over time, companies that become wasteful go out of business.

    Now, as governments and government agencies get more bureaucratic, more wasteful is there anything that stops this process?

    Do bureaucracies magically reorganize themselves and become more efficient (ie removing, reducing positions)?

    It's not that corporations are "magically" more efficient - it's that the more inefficient a company becomes the more likely it will succumb to a more nimble adversary. Governments (and their supporters) resist all efforts at efficiency.

    --
    If you're scared of your govt then you need to further restrict its powers
    Vote 3rd Party in 2016 and beyond
  15. In other news... by Matheus · · Score: 2

    Unrelated: Billionaire Bill Gates diagnosed with early stage Alzheimer's...

  16. Re:Venture capital fund - Is this another investme by Solandri · · Score: 4, Insightful

    Smallpox was eradicated because (1) it only infects humans, (2) the symptoms are highly visible, and (3) people who've had the disease are immune but no longer carriers. Once enough humans were vaccinated and infected persons were isolated, the disease was unable to find new hosts and was eradicated.

    Unfortunately this is not the case for other diseases. We attempted to eradicate Yellow Fever in the early 1900s, but it failed because the disease can infect other species. Polio has been difficult because an infected person is often asymptomatic, and can unwittingly spread the disease. Likewise, measles has a long period between when an infected person can spread the disease, and when the symptoms first appear. Malaria is probably the disease we'd most like to eradicate, but you can get malaria multiple times. So vaccination only confers a low level of immunity.

    The only other disease we're getting close to eradicating is Guinea worm. This is a parasitic disease, not a virus, but by educating people about drinking clean water or boiling or filtering before drinking, it was nearly eradicated. Unfortunately it ran into (1) above - it was thought that the worms could only infect people, and thus a global halt to infection for a short period of time would be enough to drive the worm into extinction. Then we discovered that dogs can also carry the form of worm which infects humans.

    When faced with a myriad of different problem conditions like this, the best approach is usually a shotgun approach. You throw all sorts of different things against the wall in hopes of randomly finding something that sticks. That is the libertarian philosophy. Your insinuation that libertarians require personal profit as motivation is incorrect. Libertarians are free to donate their money to whatever causes they feel are worthy, and do so all the time. What libertarians are against is being forced to donate their money to causes they personally don't feel are worthy, or being prevented from donating their money to causes they feel are worthy.

    What the GP is advocating is a market-based approach to combating diseases. A libertarian, being in favor of the shotgun approach, would approve of both for-profit and charitable means of fighting diseases. The anti-market folks (mostly liberal) would try to prevent for-profit approaches without even seeing if they would work. And likewise the pro-market folks (mostly conservative) would try to phase out charitable approaches in favor of for-profit approaches. To the libertarian, the anti-market folks can donate to the charities fighting diseases, the pro-market folks can donate to for-profit organizations fighting diseases, and everyone is happy (well, everyone except those who think they are "right" and feel they should be able to control how the "wrong" people spend their money).

  17. Re:How well will the money be spent? by PCM2 · · Score: 2

    It sounds great to wipe out a disease, but let's make sure we don't squander this money.

    There's a huge difference between "not having found a universal cure for cancer" and "squandering the money."

    People DO survive cancer, and many of them do so as a result of treatments that didn't exist decades ago.

    --
    Breakfast served all day!
  18. Re:If it ducks like a quack... by Maritz · · Score: 2

    I don't give a flying fuck what article is on that page, it's Mercola, his site exists to generate income for him and no other reason. So either link the study directly or GTFO.

    --
    I do not want your cheap brainburning drugs. They are useless for work. And I am a working man today.