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Older Adults' Forgetfulness Tied To Faulty Brain Rhythms In Sleep, Study Says (npr.org)

An anonymous reader quotes a report from NPR: Older brains may forget more because they lose their rhythm at night. During deep sleep, older people have less coordination between two brain waves that are important to saving new memories, a team reports in the journal Neuron. The finding appears to answer a long-standing question about how aging can affect memory even in people who do not have Alzheimer's or some other brain disease. The study was the result of an effort to understand how the sleeping brain turns short-term memories into memories that can last a lifetime, says Matt Walker, the author of the book Why We Sleep. "What is it about sleep that seems to perform this elegant trick of cementing new facts into the neural architecture of the brain?" To find out, Walker and a team of scientists had 20 young adults learn 120 pairs of words. "Then we put electrodes on their head and we had them sleep," he says. The electrodes let researchers monitor the electrical waves produced by the brain during deep sleep. They focused on the interaction between slow waves, which occur every second or so, and faster waves called sleep spindles, which occur more than 12 times a second. The next morning the volunteers took a test to see how many word pairs they could still remember. And it turned out their performance was determined by how well their slow waves and spindles had synchronized during deep sleep.

Next, the team repeated the experiment with 32 people in their 60s and 70s. Their brain waves were less synchronized during deep sleep. They also remembered fewer word pairs the next morning. And, just like with young people, performance on the memory test was determined by how well their brain waves kept the beat, says Randolph Helfrich, an author of the new study and a postdoctoral fellow at UC Berkeley. The team also found a likely reason for the lack of coordination associated with aging: atrophy of an area of the brain involved in producing deep sleep. People with more atrophy had less rhythm in the brain, Walker says.

70 comments

  1. With the long hours we work now... by greenwow · · Score: 1

    I've noticed my short-term memory is just crap. Working Seattle Hundreds sucks, and it sucks even more at my age.

    1. Re:With the long hours we work now... by ls671 · · Score: 2

      Dear M. Greenwow,

      May I suggest you slow down on smoking the green? There is reports that it affects short term memory. Things might not be so "wow" anymore but at least your short term memory should improve.

      --
      Everything I write is lies, read between the lines.
    2. Re:With the long hours we work now... by hackwrench · · Score: 1

      The universe is a giant state machine and we are all cogs in its machinery. The universe sends us out to investigate its infinite states.

    3. Re: With the long hours we work now... by Anonymous Coward · · Score: 0

      Mine (also a Seattleite) sucks too and I'm in my 30s. I have enough trouble trying to remember names of acquaintances, let alone celebrities or famous movies/songs.

    4. Re:With the long hours we work now... by Anonymous Coward · · Score: 0

      Are you really trying to say weed helps short term memory?

  2. Re:Wrong by Anonymous Coward · · Score: 1

    do u do anything else beside post this racist trash on slashdot?

  3. pee by bugs2squash · · Score: 5, Funny

    getting up in the middle of the night to pee doesn't help either.

    --
    Nullius in verba
    1. Re:pee by Paradise+Pete · · Score: 3, Informative

      getting up in the middle of the night to pee doesn't help either.

      Don't turn on the light and sit down when you pee. You'll stay closer to your sleep state.

    2. Re:pee by Anonymous Coward · · Score: 0

      that sounds gay

    3. Re: pee by Anonymous Coward · · Score: 0

      But then my nuts dip in the toilet water which jolts me wiiide awake.

    4. Re:pee by PopeRatzo · · Score: 2

      Don't turn on the light and sit down when you pee. You'll stay closer to your sleep state.

      Pete's on to something here. Get a dim night-light, and definitely don't turn the bathroom light on when you get up to pee. The night light is so you don't pee three inches wide of the toilet. Also, darken your room as much as possible. Little things like the blinking lights on a cable modem or router can disrupt your sleep. I used to have one of those dark masks for sleeping, but then I just taped over the useless status lights on my router and now I don't need the mask.

      Also, you can try not drinking anything for a couple of hours before bed so you won't have to get up to pee at all.

      Seriously, folks. You have to cultivate good sleep, especially as you get older. It pays dividends.

      --
      You are welcome on my lawn.
    5. Re: pee by Anonymous Coward · · Score: 0

      gay is when you don't learn to pee in your sleep. You can try sleeping on your toilet, that way no need to wake up to pee.

    6. Re: pee by Anonymous Coward · · Score: 0

      You either have a problem with your scrotal elasticity, or the water level in your toilet is too high.

    7. Re: pee by Anonymous Coward · · Score: 0

      Just wait til you're an aging elderly codger. Your nuts will hang, too.

    8. Re:pee by 140Mandak262Jamuna · · Score: 1

      Not getting up in the middle of the night and peeing in the diaper is worse.

      --
      sed -e 's/Chuck Norris/Rajnikant/g' joke > fact
    9. Re:pee by Ihlosi · · Score: 2
      Don't turn on the light and sit down when you pee. You'll stay closer to your sleep state.

      At least until you step on any of the area denial devices commonly sold under the brand name LEGO.

    10. Re: pee by Klag · · Score: 0

      Iâ(TM)ve had to get some of the dimming film to darken the display on my clock radio because itâ(TM)s just too bright. A very dim nite lite in the bathroom helped too. Getting old is no fun.

    11. Re:pee by avandesande · · Score: 1

      I use echolocation you can tell where the stream is going

      --
      love is just extroverted narcissism
    12. Re:pee by PopeRatzo · · Score: 1

      I'd argue that a black market is a free market.

      If I forget to put my hearing aid in, I'll end up peeing in the bathtub.

      --
      You are welcome on my lawn.
    13. Re:pee by Anonymous Coward · · Score: 0

      And that attitude is why you will be weeded out of the food chain earlier.

  4. Jeeze... by rgbatduke · · Score: 4, Interesting

    OK, so they did a study comparing young people and old people, where the young people all had smooth skin and high levels of sex hormones, and the old people all were somewhat wrinkled and had lowered levels of sex hormones. The young people remembered more than the old people. Hence, we can obviously conclude that having a smooth skin and a powerful sex drive improves memory.

    What's that latin again? Post hoc ergo propter hoc? Sounds so much better than in English: correlation is not causality!

    Sure, sure, they found similar correspondences in young and old people, but they still miss this point. Both could have the same independent cause, and indeed in the case of the young people it is rather likely that they do, since presumably they don't have atrophied brain parts that usually produce deep sleep but just didn't sleep deeply anyway!

    About the best one can do from this from the sound of it is: Not getting good sleep is bad for your memory.

    Wow. That's sure news. Nobody even suspected! And some people don't get good sleep because they drink too much coffee in the evening. And others don't get good sleep because they are in pain all the time. And still others don't get good sleep because they have obstructive sleep apnea. And whaddya know -- some of them have atrophy in a part of the brain that helps produce good sleep.

    I was going to say something else about this, but I dozed off for a moment there and now I forgot.

    Sorry.

    --
    Even when the experts all agree, they may well be mistaken. --- Bertrand Russell.
    1. Re:Jeeze... by PopeRatzo · · Score: 4, Funny

      and the old people all were somewhat wrinkled and had lowered levels of sex hormones.

      Listen you whippersnapper. I may be old, but I've got sex hormones coming out my ass.

      Wait, that didn't sound right...

      --
      You are welcome on my lawn.
    2. Re:Jeeze... by mnemotronic · · Score: 2

      Listen you whippersnapper. I may be old, but I've got sex hormones coming out my ass .....

      Thanks for sharing. Bartender! Nightmares for everyone!

      --
      The Russians have won. They have made the world a cesspool of distrust, greed, fear and hate.
    3. Re: Jeeze... by Anonymous Coward · · Score: 0

      There is nothing interesting about this, you've totally failed to comprehend even the simple summary. Your rant is a nasty pile of ageist nonsense:

      The take away from the summary alone is exactly opposite of what you posit. That the brain is still capable of memory, but it's not storing because the storage algorithm isn't 'running'. The corollary would have to be if that pattern (program) can be induced, storage or memory can be restored.

      And if that makes you angry, you're an ass.

    4. Re:Jeeze... by 140Mandak262Jamuna · · Score: 1

      The research was done by older researchers, so the question is, did they remember to follow the protocols...

      --
      sed -e 's/Chuck Norris/Rajnikant/g' joke > fact
    5. Re: Jeeze... by Anonymous Coward · · Score: 0

      Found the cuck.

    6. Re:Jeeze... by Anonymous Coward · · Score: 1

      The decline in Slow Wave sleep with age is well documented and well understood. Sleep Spindles are inhibitory signals to maintain sleep continuity. I suspect that memories and learning are linked to REM sleep, although most antidepressants will 'happily' remove REM sleep without much loss in cognitive function.

      Very few people will reach advanced years without some form of Sleep Disorder degrading sleep. These are treatable, old age not so much,

    7. Re:Jeeze... by slashrio · · Score: 1

      Next step of course is testing the hypothesis that cerebral atrophy is the culpit.
      So find old people with different gradations of atrophy but the same level of brain wave synchronicity and check whether their memories behave according to the theory. If not, theory falsified, if yes, go to the next step. But quickly please, because I almost turn 60.

      --
      "Trump!!", the new Godwin.
    8. Re:Jeeze... by Anonymous Coward · · Score: 0

      My understanding of it is that they found a correlation even within the groups to brain-wave sync during sleep.

      Essentially, in both groups better sync meant better memory. Additionally, older people had worse sync and memory in general.

    9. Re:Jeeze... by rgbatduke · · Score: 1

      I'm a member of the post-60 cadre myself, and all I can say is that my memory is indeed failing to some extent. I refuse to state whether or not it is correlated with my sex hormone levels, in part because I possess no good way to measure them. I'm pretty sure, however, that they aren't coming out of my ass.

      --
      Even when the experts all agree, they may well be mistaken. --- Bertrand Russell.
    10. Re:Jeeze... by rgbatduke · · Score: 1

      Hey, I'm on the wrong side of it already. In some ways, my brain works a lot better than it did when I was young. For example, when I was 18/19 I was getting B's in courses that I know teach. Then, I could barely remember the laws of physics and all of the formulas involved -- largely because I didn't understand them and couldn't derive them. Now I don't even bother preparing if I need to show students how to solve some problem out of an intro physics textbook. I can solve all of them (within statistical noise of "stupid algebra mistakes" or "misreading the problem" which I can still manage at my advanced age). Period. Usually very quickly, with a fully annotated explanation, if necessary accompanied by derivations all the way back to e.g. Newton's Laws and empirical force laws etc.

      On the other hand, if I work VERY HARD, I can learn all of the names of the students in a class I teach as long as it isn't a large group lecture class, over the course of a semester. But sadly, I forget their names even when I manage this within a year or two, with at most a very few exceptions. I can learn some things incredibly quickly -- perhaps because I have a well-established matrix of knowledge into which I can insert things, hook them up to things I already know, make sense of them, and thereby remember them in an easily accessible and useful way -- while at the same time I probably do worse at remembering piles of disconnected facts, the sorts of things I would work on "memorizing" back as a callow undergraduate. I still remember going over pages of formulas right before going into an exam, drilling them so I'd remember them long enough to get through the exam (and then promptly forgetting most of them) where what I SHOULD have been doing is learning to DERIVE them all from a tiny set of first principles that I would have used over and over (had I done this) so that I didn't EVER "memorize" them, I would have just plain learned them, as I eventually did, after I started to TEACH them.

      That's why I view studies like the top article with a certain degree of skepticism, in spite of the fact that it (apparently) attracts flames. I'm not a neuroscientist, it is true, but I am a friggin' expert on neural networks and predictive modeling and information theory, have actually written a patent application for a "true AI" that I let expire because of a lack of funding more than a lack of ability to implement it, am married to an ex-neuroscientist who is now a physician -- and I used to type all of her neuroscience papers back when she was doing research as she didn't know how to type and I type like the wind. And yes, I teach. I take teaching very seriously. I study teaching, learning, and the brain, and I teach my STUDENTS about the brain and learning as much as possible because as my anecdotes above indicate, there are indeed good ways and bad ways to try to learn things. One of the many things I teach them -- sometimes pretty forcefully -- is that sleep is indeed the time short term memory is turned into long term memory. It is also a time where the brain pulls off some near miraculous background bookkeeping and housecleaning without the active participation of our interior monologue intentional self. We (our brains) actually do "work" in our sleep and a very common experience is to work very hard on something one day, sleep on it, and return to it the next day and just "see" all at once what the solution is, even though one spent NO time actually verbally sequentially reasoning about it while awake in the meantime. I have guided students who are trying to learn physics on four hours of sleep a night (and gradually driving themselves crazy in the process) into sleeping a disciplined MINIMUM of 6 to 8, working towards a minimum of 8, and thereby rescued them from the D or F they were inevitably working themselves towards while damaging their sanity and completely destroying their personal happiness.

      Am I a Ph.D. brain researcher? No, but I am a Ph.D. and I do know a fair bit about the brain, memory, a

      --
      Even when the experts all agree, they may well be mistaken. --- Bertrand Russell.
    11. Re:Jeeze... by EndlessNameless · · Score: 1

      Your criticism is ill-considered for the following reasons:

      1. They compared between and among groups. Young people with lower sync during sleep performed worse than young people with higher sync during sleep. Same for the older group. They deliberately controlled for age in order to eliminate it as a confounding variable.

      2. They are not measuring the quality of sleep. They are measuring how two specific types of brain activity affect memory. Did you read the entire summary, or did you knee-jerk?

      3. There is independent work that supports the claim that long-term memories are formed (or finalized) during sleep. The causative element was never entirely clear before, and this study is a further investigation of that well-documented phenomenon.

      Perhaps this study uncovered the sole cause of forgetfulness; perhaps they have only discovered one contributing factor out of a multitude. Either way, it demonstrates one observable thing which clearly influences another. Good science.

      The fact that it seems to explain why older people are more forgetful---well, that's just icing on the cake.

      --

      ---
      According to the latest ruleset, this post should be modded as Vorpal Flamebait +5.
  5. I'm 72 ... by CaptainDork · · Score: 1

    ... what happened while I was asleep?

    --
    It little behooves the best of us to comment on the rest of us.
    1. Re:I'm 72 ... by Anonymous Coward · · Score: 0

      you woke three times to use the bathroom.

    2. Re: I'm 72 ... by Anonymous Coward · · Score: 0

      You were giving small children the middle finger.

    3. Re: I'm 72 ... by Anonymous Coward · · Score: 0

      You snored.
      And farted.

  6. Brain got rhythm by Anonymous Coward · · Score: 0

    So basically younger brains can shake it's booty better.

  7. Green smoke by Anonymous Coward · · Score: 0

    Meh. Smoke more green.

    Short term memory is useless anyway. Toke green herb, sleep better, improve long term memory.

    Puff puff, nerds!

    1. Re:Green smoke by Anonymous Coward · · Score: 0

      jah, smoke and write everything down. problem solved.

  8. Nice article by pranavhaldar999 · · Score: 0

    thanks for sharing this information with us

  9. New to me by Anonymous Coward · · Score: 1

    From TFA "That's discouraging because atrophy in this area of the brain is a normal consequence of aging, Walker says, and can be much worse in people with Alzheimer's."
    I thought the brain deteriorated uniformly. Stem cells might be another promising remedy for the determination.

  10. Re: Wrong by Anonymous Coward · · Score: 0

    The only racist cuck here is you, your stupid country goes to shit and you are cheerleading like a true dumbass.

  11. On the other hand.... by Templer421 · · Score: 1

    No raging hormone fired erection that just won't go to sleep so you can.

    Then there is the 5 AM morning wood.

    Things that don't happen when you get older.

    1. Re:On the other hand.... by slashrio · · Score: 1

      If those things bother you, how about castration?

      --
      "Trump!!", the new Godwin.
  12. Do sleep drugs help? by CaffeinatedTech · · Score: 1

    So do we know if chemically assisting sleep can help with these brain waves? And further than that, is there something more natural that might help this, like marijuana, or even a low dose of alcohol?

    1. Re: Do sleep drugs help? by Anonymous Coward · · Score: 0

      Smoking a couple bowls a few hours before bed always knocks me out. And I've been an insomniac since I was 8.
      You really don't want to try sleeping during onset...that will never happen.

      But hey, if these old guys are having trouble sleeping because they lose their rhythm shouldn't we be giving them metronomes?

  13. (Our Senior Citizen) Beastie Boys by Anonymous Coward · · Score: 0

    Known to let the beat...

    drop!

    (CAPTCHA melody)

  14. Re: pee -- How do you measure that? by mnemotronic · · Score: 1

    What is the official unit of measurement for scrotal elasticity? Centipeters per nude ton meater? Mega-hurts per furlong per light-year. Who will volunteer for the non-elastic (i.e. permanent deformation or fracture) measurements?

    --
    The Russians have won. They have made the world a cesspool of distrust, greed, fear and hate.
  15. Re: Wrong by Anonymous Coward · · Score: 0

    No one here knows what you mean by 'cuck'.

    That is not a word... which is not to say you are illerterate, although that is the conclusion I choose to draw ;)

  16. Haha by Anonymous Coward · · Score: 0

    Haha alzhy papy too funny haha

  17. Asymmetric degradation. by Anonymous Coward · · Score: 0

    I thought the brain deteriorated uniformly.

    The older you get, the more varied the ages of cell groups across your body.
    It varies because of activity, stress, diet, genetics and everything else.
    One of the biggest things that can affect it is diet. A shitty diet causes all kinds of damage to your insides that massively skews the ages of cells across your body, especially your digestive tract.
    This is why cancers of the digestive tract are right up there at the top of the charts, and immediate secondary products of the digestive tract (like breast cancer and prostate cancer, another 2 high ones)
    Varied age gradients increase cancer risk on top of that. Why that is is still not fully understood.
    Case in point, lung cancer, hugely common one that is easily prevented by good diet alone.
    A good case of that is Japan. Despite their high smoking incidence, they have low lung cancer rates. This is when you exclude the differences in tobacco between countries, specifically, which was originally thought as the reason.

    The biggest issue with diets today is the consumption of toxic ready-made meals. That single thing alone is the biggest issue. The processes that cook them make them both sterile and filled with toxic aldehydes from the high-temp cooking processes and cheapo shit veg oils.
    Same happens with snack food too. Pringles only have their shape due to extremely high temperature cooking in, yep, cheapo shit vegetable oils. They are horribly inflammatory.
    Inflammation causes persistent scarring over long term, exhausts useful nutrients, damaging stem cells and leading to premature ageing of cell groups, and in turn, varied age gradients across the body.
    Eliminating them would fix most common illnesses in the western world in a generation.
    Everything else, like dodgy pesticides, all of that is nothing compared to the shit food being produced every second in these massive factories shrouded in secrecy.
    They should be banned. All of them. Honestly the worst thing the human race has invented. Worse than biological weapons and chemical weapons. Hell, they ARE those things in a very literal sense.

    1. Re:Asymmetric degradation. by slashrio · · Score: 1

      Thanks for this very interesting seminar! Can we have more? Also links please. Thank you!

      --
      "Trump!!", the new Godwin.
    2. Re:Asymmetric degradation. by slashrio · · Score: 1

      Also, what would be your comment with respect to the ketogenic diet in order to slow down atrophy?

      --
      "Trump!!", the new Godwin.
  18. Actually by Anonymous Coward · · Score: 0

    Are you sure it's just not tied to passing out while watching Fox News?

  19. Feline Overlord Plot by lazarus · · Score: 2

    This explains why my fucking cat wakes me up in the middle of the night EVERY NIGHT. It's part of his evil plan to take control of my household and control the distribution of kibble.

    The last laugh's on me asshole, YOU STILL DON'T HAVE THUMBS!

    --
    I am not interested in articles about life extension advancements.
  20. Not sure if it's cause or effect by argStyopa · · Score: 1

    "Older brains may forget more /because/ they lose their rhythm at night."

    Unless figuring out a way to synchronize those ways IMPROVES memory, there's little way to tell the difference between a cause and a symptom.

    It could be that whatever mechanism is causing faulty memory is ALSO causing unsynchronized waves.

    To declare "this is why X happens" you need a much higher standard of evidence.

    Curiously, and oddly, the slashdot headline is actually more correct - they seem to be RELATED, is all we know so far.

    --
    -Styopa
  21. Melatonin by avandesande · · Score: 1

    I take 3mg melatonin at night... it helps me sleep but I also have dreams similar to when I was younger. I wonder if there is a relationship? Studies have shown melatonin levels go down as you age.

    --
    love is just extroverted narcissism
  22. The important part by roc97007 · · Score: 1

    Ok, as an old phart, my first question is, is there a TREATMENT? Yes, my memory retention has declined. It scares me. In IT, you have to keep up with current technology, which means retaining what you learned. That's become more and more difficult. (Not to the point where I can hide my own easter eggs, though.) Ok, it's good to know a possible cause. What do I do about it? I can't see myself retiring.

    --
    Oliver's law of assumed responsibility: If you're seen fixing it, you will be blamed for breaking it.
    1. Re:The important part by mileshigh · · Score: 1

      I guess you forgot to read the source article. It says the researcher has started looking into ways to build a pacemaker-like device to resynchronize the brain waves.

    2. Re:The important part by avandesande · · Score: 1

      I just research whatever I am working on and paste what I need to know into a text file I don't bother trying to remember anything anymore.

      --
      love is just extroverted narcissism
    3. Re:The important part by roc97007 · · Score: 1

      I do that also. I'm a big fan of tiddlywiki because all the data is in one file and the search feature is robust. There are ways to compensate, but it's been difficult to carry on a technical conversation when I have to keep looking up terms.

      --
      Oliver's law of assumed responsibility: If you're seen fixing it, you will be blamed for breaking it.
    4. Re:The important part by roc97007 · · Score: 1

      Ah, RTFA. I knew I had forgotten to do something.

      --
      Oliver's law of assumed responsibility: If you're seen fixing it, you will be blamed for breaking it.
    5. Re:The important part by avandesande · · Score: 1

      LOL it's terrible it also means I am screwed trying to interview 'you know the thingy' doesn't go over very well. Sad too because I still outproduce the youngins by a long shot.

      --
      love is just extroverted narcissism
  23. Re: Wrong by Anonymous Coward · · Score: 0

    which is not to say you are illerterate , although that is the conclusion I choose to draw ;)

    And the same can be said of you.

  24. I was going to respond, but ... (& prostate ca by grep+-v+'.*'+* · · Score: 1

    I was going to respond, but I forgot what I was going to say.

    That being said, i just had a Space-OAR inserted for prostate cancer radiation treatment. I've been miserable for the last two weeks, waking up every 2 hours to pee, even if there's absolutely nothing to do; it just FEELS like there is. That being said, the annoying feeling is slowly going away as I get used to it, and I'd MUCH rather have this that the standard balloon alternative it replaces.

    Even though it's bothersome as heck for a few weeks ( some discomfort may occur? How about I'm always horizontal and can't sit normally in a chair for 2 weeks?) I'd still glad I did it, even if it's the most annoying thing I've ever done to myself.

    Older guys, get checked for prostate cancer. The standard routine examination is quick (kinda like you first time having sex!) and even a scan or biopsy isn't THAT terrible. The earlier you find it the earlier and better they can treat it.

    YouTube conclusion. I'd highly recommend this annoying procedure, but ask your doctor. This is FCC approved and new -- if he doesn't know anything about it, GET ANOTHER DOCTOR.

    This is not a paid sponsorship or anything, I'm currently just an very annoyed and happy customer who's glad I did it.

    --
    If the universe is someone's simulation -- does that mean the stars are just stuck pixels?