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Two Studies Find 'Clear Evidence' That Cellphone Radiation Causes Cancer In Rats (qz.com)

An anonymous reader quotes a report from Quartz: [A] pair of studies by the U.S. National Toxicology Program found "clear evidence" that exposure to radiation caused heart tumors in male rats, and found "some evidence" that it caused tumors in the brains of male rats. (Both are positive results; the NTP uses the labels "clear evidence," "some evidence," "equivocal evidence" and "no evidence" when making conclusions.) Tumors were found in the hearts of female rats, too, but they didn't rise to the level of statistical significance and the results were labeled "equivocal;" in other words, the researchers couldn't be sure the radiation is what caused the tumors. The next scientific step will be to determine what this means for humans. The peer-reviewed papers will be passed on to the U.S. Food and Drug Administration, which is responsible for determining human risk and issuing any guidelines to the public, and the Federal Communications Commission, which develops safety standards for cell phones. The FDA was part of the group of federal agencies who commissioned the studies back in the early 2000s.

Ronald Melnick, the NTP senior toxicologist who designed the studies (and who retired from the agency in 2009), says it's unlikely any future study could conclude with certainty that there is no risk to humans from cell phone use. "I can't see proof of a negative ever arising from future studies," Melnick says. He believes the FDA should put out guidance based on the results of the rat studies. "I would think it would be irresponsible to not put out indications to the public," Melnick says. "Maintain a distance from this device from your children. Don't sleep with your phone near your head. Use wired headsets. This would be something that the agencies could do right now."
Quartz notes that when the draft results were published earlier this year, all the results were labeled "equivocal," meaning the study authors felt the data weren't clear enough to determine if the radiation caused the health effects or not. "But the panel of peer reviewers (among them brain and heart pathologists, toxicologists, biostaticians, and engineers) re-evaluated the data and upgraded several of the conclusions to 'some evidence' and 'clear evidence.'"

30 of 217 comments (clear)

  1. Longer lifespan by XXongo · · Score: 4, Interesting

    The summary neglects to mention that the strongest result of the one study was that the rats exposed to microwave radiation had SIGNIFICANTLY longer lifepans than the ones not exposed.

    Somehow I would have thought that this result was worth mentioning.

    1. Re: Longer lifespan by LifesABeach · · Score: 2

      I was thinking of putting up signs for the rats to avoid this hazardous environment.

    2. Re: Longer lifespan by Anonymous Coward · · Score: 2, Insightful

      Many rats are bred for getting tumors. There was some anti GMO study where 40% of the control group got cancer and 60% of the experimental group. These were 10 rats each. The stain of rat was for studying cancer but that's because they were bred for getting it often and young. Read further in that paper and the incidence was 100% in both groups just 3 months later but they narrowed the observation window to try to show something when in fact there was nothing.

    3. Re:Longer lifespan by sheramil · · Score: 5, Interesting

      The study also neglects to mention if the rats were exposed to human-scaled phones, or, more appropriately in my view, tiny rat-sized ones, with tiny tiny touch sensitive screens and incredibly tiny headphone jacks.

      What this study may indicate is that it's bad for humans to be around phones the size of your refrigerator.

    4. Re:Longer lifespan by nospam007 · · Score: 4, Funny

      "The study also neglects to mention if the rats were exposed to human-scaled phones, or, more appropriately in my view, tiny rat-sized ones, with tiny tiny touch sensitive screens and incredibly tiny headphone jacks."

      You show your age, gramps, not even rat-phones have headphone jacks nowadays.

    5. Re:Longer lifespan by ByteSlicer · · Score: 5, Interesting

      The summary neglects to mention that the strongest result of the one study was that the rats exposed to microwave radiation had SIGNIFICANTLY longer lifespans than the ones not exposed.

      Indeed, and it is well known that longer lifespan strongly correlates with more cancer.
      The RF radiation probably slightly increases body temperature, which helps fight off infections, leading to longer life, leading to age-related cancer.

      Also, dupe, by the same guy.

    6. Re:Longer lifespan by Misagon · · Score: 3, Informative

      That would make sense, actually ...

      Radio waves have been used to promote wound healing. It was mentioned in the earlier thread discussing the pre-publication draft of this study.

      I know of a study in which simulated cell phones were shown to promote the frequency and growth of tumours in mice that had been deliberately given cancer. That study confirms an earlier study. What would make this more credible is that this group's job in general has been to replicate junk science about RF to prove it wrong.
      The point here is that small tumours that have been caused by other sources than cell phones are more likely to survive the onslaught of the body's immune system and be able to grow to become life-threatening.

      I'm just posting these here for further discussion. I'm not a physician or biologist myself, and not a kook either. So don't shoot the messenger, OK?! Do let those who are knowledgeable enough to comment something useful comment instead.

      --
      "We mustn't be caught by surprise by our own advancing technology" -- Aldous Huxley
    7. Re:Longer lifespan by tomhath · · Score: 2

      Note that they also show the rate of cancer based on the initial population of 90 subjects, regardless of how many died during the study.

      For example, there were no heart cancers in the control group after two years, but only 25 of the original 90 rats were still alive. In the group with the highest level of exposure there was 1 cancer in the 60 that survived. Did the radiation cause that cancer? Or does the rate of cancer go up with age? Draw your own conclusions.

    8. Re: Longer lifespan by Anonymous Coward · · Score: 2, Interesting

      I work with surgical RF. It works by ohmic resistance heating. Thinking of monopolar as a miniature arc welder isn't far off. It's only reason to be RF frequency is to avoid activating nerves. Pain or muscle. The threshold is about 100 kHz.

      Bipolar RF works the same, but more like resistance welding. It doesn't cut except with specialized electrode configurations.

      I also develop ultrasonic blades. The ultrasound has nothing to do with the action, just chosen as a frequency you won't hear and get annoyed by. It works by friction ... Like a friction cutting wheel.

      Heat from any source causes coagulation. So even the most advanced surgical coagulation works pretty much the same as just a burning piece of wood or red hot poker. I've even seen toaster wire coagulation.

    9. Re:Longer lifespan by Rick+Schumann · · Score: 2

      Studies have shown that your lifespan will be SEVERELY attenuated by standing in front of a microwave dish when they take the transmitter out of Standby.

  2. Who's the asshole by Anonymous Coward · · Score: 4, Funny

    who keeps buying cell phones for rats!?

  3. Re:Non-ionizing radiation can be harmful by iggymanz · · Score: 3, Informative

    not quite true, heating sufficiently can break chemical bonds. For example, a well known consequence of working around military radar equipment is higher than average rate of tumors in eye and testicles.

    Cell phones obviously can heat tissue, a little.

  4. A perfect example of quack science... by StevenMaurer · · Score: 2, Insightful

    This is how we know cell phones are safe: they emit the radio energy of a standard flashlight, 0.6 watts to 3 watts. Radio towers, buried in the heart of cities, emit up to 50,000 watts. Even miles away, that's vastly more photons going through your body. And there is absolutely no indication whatsoever of any increase in cancer around such radio towers as you live nearer to them.

    The same thing goes for cell-phone towers, which emit a minimum of 500 watts, and can go up to thousands of watts of radio waves to reach your little phone. Absolutely zero evidence whatsoever of any increased cancer risk.

    Long term epidemiological studies have shown that non-ionizing radiation has no observable health hazard. It makes perfect sense why. The tiny amount of interactions warm the body to such a small degree, you get ten thousand times the warming effect in a hot shower. (Need I mention natural ground radiation, which actually can do chromosomal damage?)

    I can understand why non-scientific BS might be acceptable on Pinterest. But slashdot? What has this site become? News for Luddites?

    1. Re:A perfect example of quack science... by rat_herder · · Score: 2

      Why is it a fantasy? Why do you advise this?

  5. Hm... by ceoyoyo · · Score: 3, Insightful

    Looking at the data they released, I think the "equivocal" conclusion was more honest. It doesn't look like the tumor incidence results would survive correction for multiple comparisons.

    The findings that do look like they remain significant are that the male rats exposed to RF survived longer. It doesn't appear that the study was long enough to see significance in the female rats, but they were also showing that tendency.

    The tumor results are complicated by that longer survival as well. They don't look like they were corrected for that effect.

    1. Re:Hm... by Njorthbiatr · · Score: 2

      What they found was that rats who live longer have more cancer.

      Fancy that.

    2. Re:Hm... by pghmike4 · · Score: 3, Interesting
      They sacrificed the rats at 105 weeks in the table I was looking at, when looking for tumors.

      But the majority of the examples I saw showed fewer rats with tumors at 6W of exposure than at 0W. The numbers were all pretty small, and the total number of male rats (the one study I looked at) was something like ~100.

      In virtually no tumor example did the # of tumors go up with the radiation exposure.

  6. The bad news? by bobstreo · · Score: 2

    I can't afford a friends and family account for all the rats around my neighborhood. /s

  7. Ducks quack too, that doesn't make them Luddites. by az-saguaro · · Score: 3, Insightful

    Every time this subject comes up, somebody says the same foolish things. Looking at studies like this does not make one a Luddite. On the contrary, it seems that there are those with a rabid zealous passion to defend the technology whatever the cost, science be damned.

    First common mistake - "blah blah blah, it's not ionizing". True. High frequency, high energy bands, UV and gamma, cause ionization and they damage DNA and cause cancer. Radar, radio, mm - they are not ionizing, but they do have other effects on cells. Mechanisms at the cytosolic, nucleosomic, and cytoskeletal levels are not well characterized, but the gross effects are well known, even used therapeutically and as research tools on cell cultures. There are many causes of malignant transformation in cells, including non-biological vectors such as chemicals and even direct physical energy transfer (trauma - momentum & kinetic energy). Low frequency EM might not be unequivocally proven to cause cancer, but it does unequivocally stimulate cell proliferation and migration, necessary prodromes of malignant transformation.

    Two - do the math. Remember, the inverse square law. Watts by themselves do not mean much. Field or flux must be known. So, using your examples, and knowing that surface of a sphere is 4 x pi x r-squared, and doing some rough rounded off calculations:

    Cell phone, 0.6 watts at your ear, 4 inches or 10 cm from center of your brain - that is a flux of about 0.6 w / 1200 cm-sq = 0.0005 or half a milliwatt per cm-sq.
    Radio tower, 50K watts 500 feet away from your house (in which is the center of your brain) - that is a flux of about 50K w / 2.7B cm-sq = 0.00002 milliwatt per cm-sq.
    You cell phone thus has about 25 times more exposure per given time than that radio tower.
    If you spent one hour talking on your cell phone, it would impart the same energy exposure to your pituitary or pons as living 500 feet away from the tower for a whole day.

    "Long term epidemiological studies have shown that non-ionizing radiation has no observable health hazard . . ." You might be correct about that, and that ultimately is what matters for public health, but that does not negate that there are biological effects of radio frequency. Hot water burns and can kill, but that does not mean we shoudn't have hot water heaters and take baths or cook food. It just means that hot water at home must be used responsibly and safely. That is what research like this ultimately gets at. Do not derogate something as "quack science" until you actually know the full "spectrum" of the science.

  8. Re:Non-ionizing radiation can be harmful by Anonymous Coward · · Score: 2, Interesting

    There needs to be some kind of cause for it. We know how ionizing radiation causes cancer: it damages DNA. Non-ionizing radiation is physically incapable of doing that.

    Cancer can be caused by agents that don't cause DNA damage directly. For example, agents that interfere with DNA repair, increase permeability to toxic substances, or cause an inflammatory response all can cause cancer. Microwave radiation can potentially do all of those by interfering with enzyme activity or membrane functions.

  9. "Cell phone"? Bluetooth? Wifi? 2.4ghz? 5ghz? by iamhassi · · Score: 4, Interesting

    When they say "cellphones cause cancer" what exactly are they talking about? Do Bluetooth headsets cause problems? What about wifi? Is 2.4ghz safer than 5ghz? Should we tell the kids they can't have their iPads? What about wireless controllers, should kids go back to wired controllers? I sleep 2 feet from my phone, is that far enough? This article is short on details but big on fearmongering.

    --
    my karma will be here long after I'm gone
  10. All EM Waves Interact by Roger+W+Moore · · Score: 2

    The reality is these waves can interact with the body even though its not ionizing.

    Any EM wave will interact with the body because, being made of matter, a human body consists of charged particles. That is not the issue, the issue is whether this interaction is dangerous. The problem is that, as yet, there is no understood mechanism as to how EM waves which have too little energy to break chemical bonds could cause cancer and without this the warning that "correlation does not imply causation" is very important to remember.

    This certainly seems to be interesting but medical research has huge problems with contradictory and unreproducible results. So until there have been considerably more independent studies confirming this result or someone comes up with a cancer-causing mechanism that can be tested and confirmed I'm going to remain highly sceptical.

    It also seems extremely bizarre that they appear to be using an elaborate system of code words about "equivocal evidence" vs "clear evidence" vs "some evidence" etc. Normally in science we give a p-value or a number of standard deviations - it's far easier to understand this than to try and figure out how "clear evidence" maps to a p-value range.

    1. Re:All EM Waves Interact by rtb61 · · Score: 3, Interesting

      Simply probability outcomes like this https://www.youtube.com/watch?.... You alter one of those pegs and the outcome alters. Cell division is not like making a cheese sandwich, that outcome counting millions of moleculeshttps://michaelgr.wordpress.com/2008/04/06/how-many-atoms-to-encode-the-human-genome/ in the correct sequence, must replicate in the correct sequence, otherwise bad things might happen, dependent upon which part of the sequence was in error.

      So damage could be routine but the bit of DNA damage is the bit that defines the shape of you nose, buried in DNA in bit of skin in your big toe and you toe does not care what the DNA instructions are for your nose. The more damage, the more pegs altered, the more likely a specific range of DNA damage is going to occur, the ones which prevent bad cell death (dysfunctional cells should self destruct) and allow unhindered cell replication (instead of just replacing a dying cell breeding out of control, sort of like those crazy religious sects, hmm, is that why they call them a cancer on human society) and of course not be rejected by the immune system (too much DNA damage and the cell no longer recognised).

      In fact every single rat could have suffered genetic damage just that the cells died, the cells did not reproduce, the cells were eaten by the immune system, the damage did not impact the functionality of that cell (watch out though more errors can accumulate). The older the more likely as basically you keep rolling dice and eventually you get bad numbers. Alter the dice, induce a bias for negative outcomes and you will likely get negative outcomes sooner. Yep, cell replication is the trigger for cancer and lots of stuff can alter that probability outcome, the more antagonists to successful cell replication, the sooner you get a negative outcome.

      Suck it up baby, life itself is a dice roll or at least a random variability outcome during cell reproduction, sometimes shit happens. You strive to improve those odds, rather than making them worse.

      --
      Chaos - everything, everywhere, everywhen
  11. Re:DEJA VU by Mr0bvious · · Score: 3, Funny

    That's proof that cell phones cause Deja Vu.

    --
    Never happened. True story.
  12. Re: Non-ionizing radiation can be harmful by c6gunner · · Score: 2

    In fact I am assured that my comment, that a superset beyond already-proven carcinogens in our scientific knowledge base will in fact be proven harmful to human life in my lifetime, is true. I only need one.

    Well, yes, you only need one, because you're not saying anything of value. Your claim is "there's something dangerous out there", and the response to that is "yeah, no shit". Come back when you figure out which things are dangerous and can prove it.

  13. Re:Non-ionizing radiation can be harmful by sheramil · · Score: 2

    If you swallow an entire hot tub's worth of water, you may drown.

  14. Re:DEJA VU by Pseudonym · · Score: 4, Funny

    Yes. There is clear evidence that research causes cancer in rats.

    --
    sub f{($f)=@_;print"$f(q{$f});";}f(q{sub f{($f)=@_;print"$f(q{$f});";}f});
  15. Re:Non-ionizing radiation can be harmful by cstacy · · Score: 2

    Hot tubs kill people via hundreds of actual vectors none of which are cancer.

    My damn hot tub has never killed anybody. My gun is sitting on the table in the same room as the hot tub and it has never killed anybody, either.

    I assume they are keeping a murderous eye on each other!

  16. Comment removed by account_deleted · · Score: 5, Informative

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