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IBM Promised Its AI Platform Watson Would Be a Big Step Forward in Treating Cancer. But After Pouring Billions Into the Project, the Diagnosis is Gloomy. (wsj.com)

Can Watson cure cancer? That's what IBM asked soon after its AI system beat humans at the quiz show "Jeopardy!" in 2011. Watson could read documents quickly and find patterns in data. Could it match patient information with the latest in medical studies to deliver personalized treatment recommendations? "Watson represents a technology breakthrough that can help physicians improve patient outcomes," said Herbert Chase, a professor of biomedical informatics at Columbia University, in a 2012 IBM press release. Six years and billions of dollars later, the diagnosis for Watson is gloomy [Editor's note: the link may be paywalled; alternative source]. WSJ: More than a dozen IBM partners and clients have halted or shrunk Watson's oncology-related projects. Watson cancer applications have had limited impact on patients, according to dozens of interviews with medical centers, companies and doctors who have used it, as well as documents reviewed by The Wall Street Journal. In many cases, the tools didn't add much value. In some cases, Watson wasn't accurate. Watson can be tripped up by a lack of data in rare or recurring cancers, and treatments are evolving faster than Watson's human trainers can update the system. Dr. Chase of Columbia said he withdrew as an adviser after he grew disappointed in IBM's direction for marketing the technology. No published research shows Watson improving patient outcomes. IBM said Watson has important cancer-care benefits, like helping doctors keep up with medical knowledge.

90 comments

  1. Nobody ever got fired for buying IBM... by Anonymous Coward · · Score: 4, Funny

    after they replaced the HR system, no one could figure out how.

    1. Re:Nobody ever got fired for buying IBM... by Anonymous Coward · · Score: 0

      This is funny even though I got laid off from IBM last week. Thanks.

    2. Re:Nobody ever got fired for buying IBM... by olsmeister · · Score: 1

      Seriously? It may not seem like it right now, but they did you a favor.

    3. Re:Nobody ever got fired for buying IBM... by Anonymous Coward · · Score: 2, Interesting

      Was there 22 years. It used to be a place where solutions mattered. Last few years was a lesson in selling smoke and mirrors. Everything is built on a stack of lies. The Watson-jeopardy team had all questions to all answers ahead of time.

    4. Re:Nobody ever got fired for buying IBM... by Anonymous Coward · · Score: 0

      Do you they do anything but sell antiquated "enterprise" software for institutions who don't realize what a POS it is?

  2. AI is bullshit by Anonymous Coward · · Score: 0, Insightful

    AI is total BS. It is just computer programs running algorithms. There is no intelligence or even learning. And no: intelligent computers will never happen. We have trillions of dollars going into computing and we barely have usable software.

    1. Re:AI is bullshit by hey! · · Score: 1

      Insofar what an expert does follows some kind of logic, you could say the same for him.

      Human minds have quite a diverse and useful bag of tricks, which is what makes human experts so versatile. I think we're at the point where we can reproduce individual tricks from that bag and perform them with inhumanly repetitive perfection. But that perfection is actually a liability, because it leaves not room for common sense, which throws spanners into logical works all the time.

      --
      Post may contain irony: discontinue use if experiencing mood swings, nausea or elevated blood pressure.
    2. Re: AI is bullshit by Anonymous Coward · · Score: 1

      Troll

    3. Re:AI is bullshit by UnknownSoldier · · Score: 3, Interesting

      While I agree with you that the current artificial ignorance (A.I.) (*) that tries to pass for Artificial Intelligence is a joke -- nothing more then a glorified table lookup -- you're jumping the gun to say "no: intelligent computers will never happen". i.e. a.i. = Actual Intelligence.

      THE fundamental problem is that Scientists don't know what the fuck consciousness is. Without a way to measure it you can't copy it (or create it.)

      Let's pretend it is 100 years in the future, and we have ways to:

      * Upload
      * Download

      consciousness. With the ability to "clone" consciousness we _actually_ would have a way to have an intelligent computer. But yeah, until we get to THAT point, we're (probably) barking up the wrong tree with "just throw hardware at it."

      Second, you are ignoring bio-computing. If tomorrow's computers switched from using electricity to using chemistry, much the way a physical body does, then again, intelligent computers is within the realm of possibility.

      The million dollar question is: How do we get there? I'm not aware of anyone knowing. If they do know, they sure as hell aren't saying -- and I can't blame them. Think of the implications: If we could clone human consciousness effectively death would be wiped out which I'm sure there are enough bad sci-fi writers out there who have discussed this before.

      Your lament about the sorry state of software reminds me of that old Murphy's Computer Law joke:

      Weinberg's Second Law: If builders built buildings the way programmers wrote programs, then the first woodpecker that came along would destroy civilization.

      (*) Yes, A.I = artificial ignorance was intentional.

    4. Re:AI is bullshit by Aighearach · · Score: 1

      "Common sense" is usually wrong, though. It is a cliche that generally refers to "mount stupid," knowingly or not.

    5. Re:AI is bullshit by hey! · · Score: 2

      I wouldn't say it's "usually" wrong; that's way too strong. But it sure is unreliable.

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    6. Re:AI is bullshit by null+etc. · · Score: 1

      What kind of tripe is this that you're spewing? While I agree that replicating consciousness seems like it would be an impressive and groundbreaking accomplishment, it's certainly not a pre-requisite for intelligence.

    7. Re:AI is bullshit by UnknownSoldier · · Score: 1

      > consciousness ... is certainly not a pre-requisite for intelligence.

      OK, prove it. Show me intelligence *without* it (*).

      (*) Once we agree on _exactly_ what consciousness is.

  3. Whose billions? by xxxJonBoyxxx · · Score: 1

    >> Six years and billions of dollars later

    If it was IBM's gamble, then nothing of value was lost. If, however, the billions were invested by medical teams duped by impossible promises, then that's a different story.

    (Story is paywalled and I'm too lazy to read TFA before commenting.)

    1. Re:Whose billions? by Anonymous Coward · · Score: 0

      Given IBM, I'd assume the latter.

      I'm still somewhat satisfied that people are still willing to spend resources on pure R&D though, even if I think they're barking up the wrong tree.

  4. Pouring billions into Watson? by m00sh · · Score: 1

    I doubt IBM poured billions into oncology Watson. All it was doing was creating recommendations for doctors from reading patient reports and treatment research reports.

    IBM sure poured billions into Watson and it's their biggest future product. The oncology seems like a small side project.

    1. Re:Pouring billions into Watson? by LifesABeach · · Score: 1

      WATSON is able to access existing knowledge. A.I. in general is good at searching and using known problem solving methods. But think outside of the box? It does not look good.

    2. Re:Pouring billions into Watson? by Anonymous Coward · · Score: 0

      There is no single Watson. It is just a marketing term, used both for these multi-million dollar showcase-projects, as well as their "cognitive computing" APIs. Most of those APIs where acquired with the AlchemyAPI company acquisition, i.e. they are not based on any magical Watson-technology..

      Also, those APIs are not that dissimilar from what e.g. Microsoft or Google are providing.

  5. Cancer is cured already by Anonymous Coward · · Score: 0

    I forget the name of the drug, a knowlegeable slashdoter will remind us. The problem is the drug is old and unpatentable, so Big Pharm has no interest in providing it, and it is no wonder oncologists do not often opt to use for treatment because they are being bombarded by Big Pharm with incentives to instead choose less effectice, expensive patented drugs for treating their patients. There is no profit incentive to curing cancer, so that it was cured is ignored.

    1. Re:Cancer is cured already by Anonymous Coward · · Score: 1

      dichloroacetate is probably what OP is referring to

    2. Re: Cancer is cured already by Anonymous Coward · · Score: 0

      boring! gimme $$$$!!1

    3. Re:Cancer is cured already by Anonymous Coward · · Score: 0

      For prevention, regular water-only fasting is supposed to help:

      https://www.ncbi.nlm.nih.gov/p...

    4. Re:Cancer is cured already by AvitarX · · Score: 1

      Didn't it show early promise, but not work?

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    5. Re: Cancer is cured already by Anonymous Coward · · Score: 1

      Yup, kills the liver. Considering the huge grants and Nobel prizes and personal fulfillment that would come from curing cancer, the idea of a secret cabal is on level with rumors of Exxon hiding the technology for 500mpg cars.

  6. IBM should get into eye health by mwvdlee · · Score: 3, Funny

    Judging from the other comments, IBM's AI system has improved human vision to a perfect 20-20 hindsight.

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    1. Re:IBM should get into eye health by omnichad · · Score: 1

      Eye health is already too competitive

  7. watson's finger by trb · · Score: 3, Informative

    Watson beat people at Jeopardy because it always got to answer first, because its button-pressing finger was faster than a human's button-pressing response. A fairer assessment of Watson's Jeopardy-playing abilities vs humans would have Watson respond with the same button-mashing-delay profile as its competitors. Beyond that, the relevant question is not whether Watson can beat humans at Jeopardy, or mash a button faster than a human, but whether it can analyze data better than a human to detect cancer (or solve whatever medical problem). And for the most part, it doesn't matter whether the answer comes back in 10 ms, 300 ms, or a a minute, or an hour. Like with any other tool, the question is whether it can help get the job done better for a reasonable price.

    1. Re:watson's finger by shadowrat · · Score: 2

      also, nobody is expecting Ken Jennings to go around diagnosing cancer.

    2. Re:watson's finger by Anonymous Coward · · Score: 0

      IBM also deliberately blurred the line between making statistical correlations between cancer and early symptoms and "Watson will cure cancer."

    3. Re:watson's finger by nwf · · Score: 1

      But with an online course, he may be better than Watson.

      --
      I don't know, but it works for me.
    4. Re: watson's finger by Anonymous Coward · · Score: 2, Informative

      Watch the PBS NOVA on Watson. They accounted for the delay for humans to buzz in and intentionally made the computer wait to give a âoefairâ chance. The rest of your post is spot on about fast turnaround not being applicable in all use cases.

    5. Re: watson's finger by Anonymous Coward · · Score: 1

      I saw that special, and they mostly just uncritically reported what IBM was saying, which was a tad one-sided. Ken Jennings talks in more detail about the buzzer advantage (or not) in this blog post. While he starts off by saying "[s]ome have called this an unfair advantage; I’m inclined to think of it as a fair one", he goes on to say this:

      [I]t’s certainly true that Watson needed that speed advantage to hang with top human players.

      I think that's a key quote. He writes quite a bit to defend IBM, but if even he acknowledges Watson "needed" its speed advantage to win, doesn't that pretty much say it all?

    6. Re: watson's finger by Anonymous Coward · · Score: 0

      Iâ(TM)ve always thought Jeopardy was an idiot savants game, good for those with hyper fast recall but maybe missing the attributes that make good engineers and scientists.

  8. AI is not a fast path by oldgraybeard · · Score: 1

    because all AI can do is manage the information it is given. Could it make a leap? Yes if the right information is present and the right questions are asked.
    Today's AI is not really there yet, today it is just a big automated filter and matching machine there really is not any intelligence behind it ATM.

    No one has figured out how to program a concept in to data. No one knows yet how to program thought, consciousness in to an algorithm. At least that I know of.

    Just my 2 cents ;)

  9. It's TIME to STOP by Anonymous Coward · · Score: 1

    I know the Washington Post does it but that doesn't mean that putting periods in headlines looks any less fucking retarded. And don't go starting with Huffington Post "This Is The Most Scandalous Detail Of What Happened, And Here's How You Should Feel About It" headlines either. If I wanted entertainment/news I would go to Maddox's site because even though he sucks, he's still better at it than any of you ever will be.

  10. Not really suprised by EvilSS · · Score: 1

    One of the problems with a field like oncology (or medicine in general) is that the AI has to rely on training from humans, using source material generated by humans. Which leaves it with the same problem humans have: research is fast evolving, sometimes biased, incomplete, or experimentally flawed, and oftentimes contradictory from study to study. Seriously, just go look up any complex biomedical subject on pubmed and start reading studies. You will find results all over the place. This is why meta-analysis has become so popular, trying to find consensus in a contradictory jungle. Add in selection biases in its training (something articles have brought up when talking about Watson's oncology uses), and it's no wonder it's spitting out gibberish. The squishy sciences are squishy and amazingly complex.

    --
    I browse on +1 so AC's need not respond, I won't see it.
    1. Re:Not really suprised by ceoyoyo · · Score: 1

      It's not spitting out nonsense (generally), it's just not doing better than a person would.

      The reason is that going off datamining isn't guaranteed to give you better results. YOu have to have a situation where all that data is actually meaningful.

      The problem with oncology is that there are some cancers where a specific mechanism can be targeted, there's test for that situation, and a specific drug. A human can read a + on a piece of paper and prescribe the appropriate drug just as well as Watson can.

      The other situation is where there isn't a magic bullet, so you have to use one of only a few more general treatments. While those have general tendencies, that's pretty well known, and there's no particular reason to think there's information in general health records that would help you do better. So again, Watson does about the same as a person would.

    2. Re:Not really suprised by EvilSS · · Score: 1

      So again, Watson does about the same as a person would.

      Except if you read up on it, it didn't. It did worse. In some cases giving out completely inappropriate treatment suggestions a newly minted oncology resident would know are bullshit. Much of this has been attributed to mistakes and biases made in its training.

      --
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    3. Re:Not really suprised by Aighearach · · Score: 1

      If the overall performance is similar to a human, but some of the mistakes it makes are as easily identified by a human as you presume, then having the human reviewing the machine performance would give a better result than just the human or just the computer.

      Alas, it was just bullshit, and the humans also make mistakes that look stupid to other humans.

    4. Re:Not really suprised by EvilSS · · Score: 1

      I'm not presuming, I'm stating what has been reported from the people using it. If the results are no better, and sometimes worse, than a human then it is wasting time and money. Having an under-performing co-worker doesn't make the rest of the team better. It makes them less efficient.

      --
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  11. they put the cart before the horse by RhettLivingston · · Score: 1

    For AI to shine with anything this complicated, you really need detailed and consistent testing. This is where tech needs to go first in medicine. In very many areas, it would help to have a massive increase in testing and fidelity of the tests.

    After the success of the genome project, we should have moved to a massive effort to develop cost efficient full system scanning and testing instead of starting the brain project.

    We should launch a project to figure out how to measure every aspect of health imaginable in a fashion that allows it to be done as a checkup once a year. It should include things like somehow measuring gene activity at thousands of points within the body, very detailed measurement of cognitive performance to detect changes, detailed hearing and sight measurements (not just clarity but speed of focus, comprehension, etc.), checking the performance of nerves throughout the body, etc. - detail like never before.

    Then, we would have the data needed to advance medicine and we'd definitely have a need for AI to interpret that volume of data.

    In short, our medical sensor technologies suck. Take $50 billion per year away from defense and spend it on this until the problem is fixed. The payoff would change the world.

    1. Re: they put the cart before the horse by Anonymous Coward · · Score: 0

      I completely agree. As a measurable and testable science, medicine is way behind, so much so that it sometimes looks like voodoo magic. We need better and more comprehensive tests, down to celular structures.

  12. Can Watson cure cancer? by Anonymous Coward · · Score: 0

    To cure cancer and to "match patient information with the latest in medical studies" are completely different things. No wonder they suck, if they can't even get that distinction.

  13. The current approach to AI is a DEAD END. by Rick+Schumann · · Score: 2, Insightful

    I've said it before, I'll keep saying it: until we actually understand how a biological brain produces the phenomena we call 'thinking', we will not be able to create 'machine intelligences' that match or exceed human beings. Period. It's 'magical thinking' to keep hooking up more and more processors and throw more and more data at the same half-assed software and expect it to suddenly be smart and cognitive like a human brain. 'Deep learning algorithms' are just a very small part of the total answer, and that's all they've been obsessively focusing on.

    Now, what they should be investing 'billions and billions of dollars' in, is research and development of newer, better instrumentation for observing a living brain in action (and I do NOT mean 'a better fMRI, I mean invent something that's a new and different approach). Only when we can see the total system in action will we even have a chance to understand how it works, the problem being that once it's dead, it's dead, and dissecting it isn't going to show you what you need to see.

    1. Re:The current approach to AI is a DEAD END. by Anonymous Coward · · Score: 0

      I sort of feel that when our technology is advanced enough to be self replicating, self repairing, flexibly fueled, mobile, advanced enough to replicate human though and action that there will be no meaningful difference between our technology and the cellular organics that we already have.

      In the same manner, I feel that when we do completely understand the brain, and build a technology capable of replicating its processes, that it will be indistinguishable from a brain.

      That is, if given the same usage requirements (must fit in and be fueled by a 6 foot biped). Maybe we would end up with a "better" brain by integrating newer sensory inputs with it, or by using wireless communications to have 1 large brain run multiple bipeds or other sensory/motor platforms.

      Given that we've got the organics, maybe we need to figure out how to grow and specialize brain tissue, and how to integrate inputs with it (I feel that we've done a little with optics replacement here) before worrying about silicon or AI.

      I also think that the Earth is a fantastic spacecraft, so I'm probably nuts.

    2. Re:The current approach to AI is a DEAD END. by Anonymous Coward · · Score: 0

      The suggestion is pointless because AI != Strong AI
      and Strong AI is impossible to achieve (See Searle's Chinese Room thought experiment). No digital computer as we know them (binary systems) will ever have consciousness. Conscienceless is a property only observed in healthy, living brain. Understanding how consciousness arises in healthy living brain is probably a worthy endeavor, for medical neurological and psychological purposes, but not for the purposes of developing Strong AI, which, again, can never be achieved. For similar reasons, a project intended to develop as-fast-as-light spaceflight will fail. There are limits to what a digital machine bound by binary logic can do, and even if we understood the source of the phenomenon of consciousness, it could not help achieve Strong AI

    3. Re:The current approach to AI is a DEAD END. by Anonymous Coward · · Score: 0

      Is this because 'consciousness' starts with 'c'?

    4. Re:The current approach to AI is a DEAD END. by ljw1004 · · Score: 1

      I've said it before, I'll keep saying it: until we actually understand how a biological brain produces the phenomena we call 'thinking', we will not be able to create 'machine intelligences' that match or exceed human beings. Period. Now, what they should be investing 'billions and billions of dollars' in, is research and development of newer, better instrumentation for observing a living brain in action (and I do NOT mean 'a better fMRI, I mean invent something that's a new and different approach).

      There's a HUGE market today for the kinds of things that the current machine-learning approach does plenty well enough at at looks like it has a lot more growth area - license-plate recognition, facial recognition, image recognition, medical imagining recognition in the case of Deep Mind. It looks like the billions that are being invested today are a good investment.

      And you propose switching that investment to a speculative thing that might bear fruit in 50-100 years time, and if it did then the result would be a general-purpose intelligence that replaces a lowly-paid human being? Why should someone invest billions in that?

    5. Re:The current approach to AI is a DEAD END. by Rick+Schumann · · Score: 1
      That's the point it DOESN'T 'do the job plenty well enough' it always falls short of the mark because it has ZERO capacity to actually THINK, your dog or cat has better cognitive ability, and people will trust this half-assed excuse for AI too much and disasters will happen.

      And you propose switching that investment to a speculative thing that might bear fruit in 50-100 years time, and if it did then the result would be a general-purpose intelligence that replaces a lowly-paid human being? Why should someone invest billions in that?

      They're putting short-term profits ahead of something that isn't garbage. Face it: the so-called 'AI' they keep trotting out has had billions invested in it, thinking it's going to be Just Another Design Cycle, and it turns out that it falls short of the mark but they have to make their money back, and marketing bastards will hype it and hype it and hype it, along with the media (who doesn't know any better) and convince us it's the Real Thing instead of half-assed.

    6. Re:The current approach to AI is a DEAD END. by ljw1004 · · Score: 1

      That's the point it DOESN'T 'do the job plenty well enough' it always falls short of the mark because it has ZERO capacity to actually THINK, your dog or cat has better cognitive ability, and people will trust this half-assed excuse for AI too much and disasters will happen.

      I think what we've discovered is that the "capacity to actually think" is by and large unimportant for most of the needs we have -- good-enough large scale image recognition, good-enough medical imaging assessments, and others that I listed.

      Disasters? You'll have to spell out why you say the "ability to think" or general-purpose intelligence will lead to fewer disasters rather than more. Personally, I reckon it would lead to more disasters just through sheer complexity and unpredictability and un-debuggability. If a "thinking" industrial robot kills a human, how the heck will we debug that or fix it? but if a half-assed-excuse robot kills a human, we can assess whether its image-recognition failed, or some other part of it failed, and address it. Similarly for a machine that controls an industrial process.

    7. Re:The current approach to AI is a DEAD END. by ChatHuant · · Score: 2

      > until we actually understand how a biological brain produces the phenomena we call 'thinking', we will not be able to create 'machine intelligences' that match or exceed human beings.

      I don't know; depends on your definitions. To me, an intelligent machine is defined by its behavior, not by its internal design or building materials. We can probably build something that behaves very closely to a human, even though internally it's built of switching silicon, or ants running through tubes.

      Historically, our machines very seldom copy nature's designs and materials. On the contrary, we have a lot of history building machines that perform a given function using different designs and materials than the natural models. We didn't understand how muscles work until very recently, but even thousands of years ago we could build 'lifting machines' that matched and exceeded human beings, using wheels, pulleys, gears and other things that don't exist in nature. Similarly, our flying machines fly faster and can carry more load than any bird, but, except for toy models, none of them use flapping wings, nature's almost universal design. So, I don't think a deep understanding of the brain function is a necessary item for designing intelligent machines either.

      Or are you saying that intelligence can only exist on a biological substrate, or that the architecture of the human brain is the only possible design that supports intelligence?If you do, I think it's a very dubious and, as far as I know, unproven statement.

    8. Re:The current approach to AI is a DEAD END. by Kjella · · Score: 1

      It's a dead end if you want to build Lt. Cmdr. Data, but honestly I just want a glorified Roomba. I mean we struggle to make a burger flipping robot, imagine having a chef in your kitchen 24x7x365 and for bonus points it'll set the table, be your waiter and clean the dishes. And that can't just vacuum the floors but scrub the toilet, dust the furniture, rinse the sink, clean the windows and so on. And that can take my dirty laundry, sort it, wash it, dry it, iron my shirts and hang them in my closet. I don't think there are physical limitations to this, it's that we can't produce "dumb" intelligence cheap enough. No consciousness or real creativity needed, just small variations on a theme.

      --
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    9. Re:The current approach to AI is a DEAD END. by 110010001000 · · Score: 1

      I never understood why people think image recognition is new "AI". It isn't. License plate readers (and image recognition) have been around for decades.

    10. Re:The current approach to AI is a DEAD END. by ljw1004 · · Score: 1

      I never understood why people think image recognition is new "AI". It isn't. License plate readers (and image recognition) have been around for decades.

      Image recognition was indeed around for decades. It was based on convolutions for edge-detection, haar cascades for face recognition. You'll have used these if you had a camera with face detection up to a few years ago. If you've coded with OpenCV you'll have used these APIs, e.g. https://docs.opencv.org/3.4.1/...

      It was an old technology that had run its course and really was a dead end. It wasn't making progress. It required too much custom human coding for things you wanted to recognize, and it was hit-or-miss.

      When machine-learning neural networks came of age in the mid 2010s it was a game-changer. It recognized far more things in far more difficult images. Neural networks of course had been around for decades too. What made them come of age was (1) vast tagged training datasets, (2) fast enough hardware to run the training at scale.

    11. Re:The current approach to AI is a DEAD END. by Rick+Schumann · · Score: 1

      I think what we've discovered is that the "capacity to actually think" is by and large unimportant for most of the needs we have

      Yeah? Who the hell is this 'we' you're referring to? Not anyone I've ever talked to. I think you're making that up, and the 'we' is actually just 'you'.

      If a "thinking" industrial robot kills a human, how the heck will we debug that or fix it?

      At least you can then ask it why it did what it did, instead of even the programmers that wrote it telling you "We have no idea why it did that", which is the current 'state of the art' in AI; even the programmers have no idea what's going on 'under the hood' when it's running.

    12. Re:The current approach to AI is a DEAD END. by ljw1004 · · Score: 1

      [I think what we've discovered is that the "capacity to actually think" is by and large unimportant for most of the needs we have] ... Yeah? Who the hell is this 'we' you're referring to? Not anyone I've ever talked to. I think you're making that up, and the 'we' is actually just 'you'.

      As you wrote, "that's all they've been obsessively focusing on". The "they" in your sentence are the ones who presumably think that deep learning is good enough for their purposes, else they wouldn't pouring their billions into it. I'm just describing to you what the market has perceived, which you yourself observed too.

    13. Re:The current approach to AI is a DEAD END. by Rick+Schumann · · Score: 1

      Sure, and what I'm saying is that they know it's garbage and they're selling it anyway because otherwise they know investors and stockholders will crucify them. Meanwhile if it's anything involving possible harm to or loss of human life (e.g., self-driving cars) their legal departments have assured them that the projected losses from paying out settlements will be trivial compared to the profits.

  14. Why is it a surprise! by Anonymous Coward · · Score: 0

    Poured billions into an assumption that genes cause cancer.. phew..
    They should have researched "WFPB"

    Hippocrates: “Let food be thy medicine and medicine be thy food.”

  15. Not yet there by Artem+S.+Tashkinov · · Score: 4, Informative

    Maybe because finding patterns without actually understanding anything is not really "intelligence". The AI hype is slowly dying and even non-IT/non-science-related people finally have finally come to a realization that
    1) AI is not a magical pill that can solve all the problems in the world
    2) There isn't too much "intelligence" in AI
    3) Coding real intelligence is a lot harder than using throwing reinforced convolutional neural networks at everything
    4) We do ... not understand how these trained networks operate and that turns them into a black box you cannot really trust and which is bound to give absolutely wrong results.

    It's not like we understand how the human brain operates but we have certain reasons to believe it's mostly rational, intelligent and infallible (with exceptions, of course) since it has got us here - the age of technology and an improved quality and increased length of life which no other animal has been able to achieve.

    I'm not against reinventing the biological intelligence that the human beings possess but it surely looks like we haven't come close to it.

    1. Re:Not yet there by Anonymous Coward · · Score: 0

      Agreed, very much. There seems to be some weird refusal by society and government to invest in the scientific research needed to solve problems. If we invested in cancer research like we do war research - we'd be saving a lot of lives. For reasons I don't understand people would rather fund war, and try these pie-in-the-sky solutions to our actual problems.

  16. Huh? by Anonymous Coward · · Score: 0

    No published research shows Watson improving patient outcomes. IBM said Watson has important cancer-care benefits, like helping doctors keep up with medical knowledge.

    Why does this sound like code whereby "helping doctors keep up with medical knowledge" really means "spending hours determining just how fucking badly Watson is at treating cancer".

    I swear, everyone runs around saying "yarg, teh apps and teh AI" when they really have no fucking clue but they're hoping the idiots will keep throwing money at them.

    People, stop listening to the tech pundits ... they don't know a fucking thing.

  17. No published research? Or no need? by Stonent1 · · Score: 1

    "No published research shows Watson improving patient outcomes."

    Would a doctor want to publish research showing that their expensive need is diminishing?

    1. Re:No published research? Or no need? by Angry+Toad · · Score: 2

      You know who gets cancer? Doctors. Their kids. Pharma execs. Government regulators and their wives and husbands. Billionaires. Mob bosses. Everyone. Nobody is sitting on a cure.

    2. Re:No published research? Or no need? by moehoward · · Score: 1

      Citation, please.... for all of your assertions.

      --
      "If you want to improve, be content to be thought foolish and stupid." - Epictetus
    3. Re:No published research? Or no need? by Angry+Toad · · Score: 1

      Seriously? Ain't nobody got time for that. All I can cite is from personal experience, and I've been around cancer for quite a few years. Billionaires? Did Jobs not pay the cancer mafia maybe?

    4. Re:No published research? Or no need? by Aighearach · · Score: 1

      Please provide a citation for your claim that conversation about technical subjects is restricted to published academic materials.

    5. Re:No published research? Or no need? by Anonymous Coward · · Score: 0

      Jobs refused treatment at a time when it might have saved him.

  18. Training by Roger+W+Moore · · Score: 2

    What you mean by "common sense" is really just information gained from years of training which the human brain has. Hence, when even the most unusual situation occurs, the human brain has got something to compare it with and can come up with some sort of reasonable action even though it might not be the optimal one.

    This is the advantage we have over AI algorithms: our brains can receive, interpret and learn from a massive variety of data and they do this every hour we are awake. This gives us a huge breadth and depth of experience to draw on when handling unknown situations. Unfortunately, AI systems can only currently learn from the limited set of data that they have been programmed to understand and, until that changes, humans will always have the upper hand dealing with rare/unusual situations.

    1. Re:Training by hey! · · Score: 1

      I had something slightly different in mind. To a hammer AI trained on nails, everything looks like (possibly a very weird) nail. Yes, as a result of life experience, in a human's head the spanner will clamor to be used.

      --
      Post may contain irony: discontinue use if experiencing mood swings, nausea or elevated blood pressure.
  19. If IBM had bothered to check with the experts by Jodka · · Score: 2

    Well professional bionformaticians had already been working on the problem of personalized medicine and medical diagnosis before IBM and Watson got involved. If you listen to them, there is a clear consensus of how that is is going to work in the future.

    Part 1: Because of a dependence of both disease and the effectiveness of treatments upon personal genetics, every person will get sequenced at birth. That will do at least three things: reduce what otherwise appears as statistical noise in assessing treatment efficacy by resolving interdependencies between the treatment and personal genetics, improve estimates of the likelihood of any individual developing a disease or disorder, and help to identify the best treatments for specific individuals.

    Part 2: Every patient treatment and its outcome become a trail logged into a massive database along with the patient's medical history and genetics. Currently, massive amounts of information about the effectiveness of treatments is discarded because the records of treatment after a drug is released are not accumulated. Now, before a drug is introduced to the market, there are clinical trials on a subpopulation, and that becomes an authoritative record of the drug effectiveness. That is a tiny fraction of the potential information out there and insufficient to assess interactions of drugs with other factors such as genetics.

    One of the barriers to implementing that system is the price of sequencing, about $1000.00/person. Prices are projected to fall until sequencing becomes ubiquitous.

    The other barrier is privacy legislation (HIPAA) and financial incentives acting on institutions against information sharing. Despite endless funded government initiatives to implement sharable electronic medical records, patient medical information remains siloed within provider and insurance networks. Rather than work to share information, those institutions are competing to build the largest silo. (This circumstance exemplifies a typical type of government ineptitude, which is to continuously and futilely throw enormous sums of money at a problem rather than simply and cheaply reforming the legislation and regulation giving rise to the perverse incentives which created the problem. Information sharing for research medical use to benefit personalized medicine was the main driver behind the U.K. slackening medical records privacy, demonstrating that in the U.K. not all government officials are complete idiots.)

    Finally, the main point of this post: The bioinformaticians have wished for that future because they knew that the problem of personalized medicine was information-starved before IBM threw billions at the problem. Given adequate information, the computational solutions of personalized medicine are already known by those humans with domain-specific expertise.

    If IBM had instead invested those billions in reducing the cost of sequencing further and in lobbying government to fix the stupid incentives and restrictions acting against medical information sharing, the problem could have been solved by now. Another case of someone with a hammer looking for nails by pounding on things to see if they move.

    Had Watson been genuinely intelligent, it would explained all that that IBM.

    --
    Ceci n'est pas une signature.
    1. Re:If IBM had bothered to check with the experts by Anonymous Coward · · Score: 0

      We need stronger laws, not a weakened HIPAA. Profit driven industry will never be trustworthy. As long as there are alternative uses for private data, they will take advantages.

      We need the law to allow sharing, but with strong and viciously toothed penalties for exploiting data for anything other than legally approved purposes.

    2. Re:If IBM had bothered to check with the experts by Jodka · · Score: 1

      We need stronger laws.

      Wrong. We need smarter laws.

      --
      Ceci n'est pas une signature.
    3. Re:If IBM had bothered to check with the experts by Aighearach · · Score: 1

      Smart laws. Smart. Just stick them on the blockchain. /s

      I do totally agree though. But without a national ballot measure system, there isn't any sort of mechanism to implement smart laws. You could write a smarter law, give it to your congress critter, and even if they got it passed, it would be a totally different law that they actually passed.

      Our whole system of government is built around making sure the government isn't too smart! Smart governments are too good at protecting their own power.

  20. Oh noes by bettodavis · · Score: 1

    Over-hyped products and deceitful marketing failed us again.

  21. Cancer wrong problem domain to start with by Anonymous Coward · · Score: 0

    Seems like they should have started with differential diagnosis or something more suited to Watson

  22. Theranos? by Parker+Lewis · · Score: 1

    Difference between this and Theranos is that I hope IBM can give back some invested money. Probably they don't care that much as any day or another we'll see a "Watson AI will solve problem X" news again and people will put money on it again.

  23. Par for the course for AI by OneHundredAndTen · · Score: 2

    The traditional modus operandi of the AI community remains the same as it was from its inception: some problems are solved initially with spectacular results, and optimistic extrapolations are made on the basis of such successes to other problems - which, invariably, turn out to be far more difficult to tackle, with the ensuing disappointing results. The AI community seems to have forgotten its past, and is therefore condemned to repeat it, as we are seeing with Watson and with the digital assistants, the usefulness of which remains extremely limited.

    1. Re:Par for the course for AI by sphealey · · Score: 1

      Apologize - mouse slipped resulted in bad moderation. Please mod this up - it is a good comment.

  24. Evolutionary Origins of Cancer by js290 · · Score: 1

    "A 1.6 Billion-Year-Old Accident Waiting to Happen" http://bit.ly/18a3ul5

    --
    "Tempers are wearing thin. Let's just hope some robot doesn't kill everybody." --Bender
  25. IBM Is Missing Out by Scarletdown · · Score: 2

    They are missing out on a major opportunity here.

    IBM has this AI thingie called Watson. Right now they are tasking it with cancer related programming.

    Don't they have enough nerds there to convince their bosses to give it proctology programming?

    Then after they feed the patient a laxative that they can call No Shit Sherlock, the AI's controller can put it to work with the command, "Dig Deeper Watson."

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    This space unintentionally left blank.
    1. Re:IBM Is Missing Out by Anonymous Coward · · Score: 0

      Watson is used internally for searching documents/wikis/knowledge bases/etc. , it's craptastic even at that. Most of the nerds have either been RA'd b/c they're 40+ or they just gave up; after all the new direction is all about diversity and inclusion, along with hiring 3-4x lowend employees for one highend employee. They're going down the route of the typewriting monkeys.

  26. Watson IBM is like my old doctor by nospam007 · · Score: 1

    He's just not as good as a young experienced one. Old doctors assume they've seen it all and 70% of the customers are diagnosed as 'stomach flu' anyway, just on general principle.
    And nobody is as old as IBM.

  27. Treatments are evolving too fast by martinX · · Score: 2

    If "treatments are evolving faster than Watson's human trainers can update the system", wouldn't the same be true for oncologists trying to keep up with the latest and greatest?

    --
    When they came for the communists, I said "He's next door. Take him away. Goddam commies."
    1. Re:Treatments are evolving too fast by urusan · · Score: 1

      All sophisticated modern AI systems (except possibly Deep Learning) suffer from the knowledge acquisition problem https://en.wikipedia.org/wiki/... Deep learning has its own different problems (ex. how did it get that answer? nobody knows!), but if things change you can basically just retrain it with the newest data.

      As your system/model gets bigger and bigger with more and more moving parts (dimensions, sub-models, rules, algorithms, data, etc.), it becomes more and more brittle, because all these different parts are interrelated, so moving one part can cause many others to shift and stop working. In particular, in an active field like cancer research you may have sudden and massive shifts that invalidate or alter a lot of your previous rules and data, setting you back so much that it's basically like starting over. Worse yet, you need to figure out which parts were invalidated by the new change and which data is still relevant. There are often situations where the scale is such that you require millions of EXPERT man hours to make the required changes. Worse yet, the often intense interdependence between components means that a large team putting in these millions of hours will have a crushing communication overhead. At this point, you just don't have the manpower available, no matter who you are, and with the communication overhead it may simply be impossible to make the changes required in any reasonable timeframe, no matter how many resources you have available. Once you can't make changes in any reasonable timeframe, the world moves on and you have to give up eventually, especially when further massive shifts put you deeper and deeper into technical debt.

      Comparatively, many human doctors can each independently learn these things. It's still expensive, but it's a smaller cost per doctor spread out over many doctors, with very little communication overhead. Humans are much better at learning from relatively small amounts of data and/or theoretical models presented to them. The main downside here of course is inconsistency, with some doctors not learning the new research properly, leading to bad outcomes. Also, if it were possible to make the change to the AI system, then it could be replicated at scale, including scaling up for demand. You can't suddenly train many new oncologists, it takes years.

      Deep Learning has a similar but less severe problem, since now it only relies on the data, but it does rely on a massive quantity of data. If there is a massive shift in our understanding, you need to either root out data that teaches it the wrong thing (likely the label is wrong in light of new developments, in your typical supervised learning use case) or you need to overwhelm the incorrect data with right data. Either solution ALSO relies on experts, but unlike the knowledge acquisition problem that most models suffer from, they do not need to communicate (only focusing on whether each isolated piece of data is correct) and they don't need to be mythical doctor-engineers that can rewrite rules while deeply understanding the domain (or pairs of domain expert and engineer that work in conjunction) since the domain experts can use a tool created by the engineers to create the data, or the data can be scraped from other sources. Once your data is corrected, you simply need to retrain the system.

      Alas, deep learning is far from a silver bullet. It often needs obscene amounts of data to perform acceptably, and the more data it needs to learn, the more expensive it is to build and brittle it is during maintenance. Plus, there seems to be some areas it just can't handle, even with sufficient data. It excels the most when the problem space doesn't change very quickly and you can get lots of data about it (ex. natural language translation, photo recognition, etc.). A cat isn't suddenly going to be something else tomorrow, and cat photos are plentiful, thus cats are easy to identify with deep learning.

      So, right now you have useful t

  28. This is exactly what I thought would happen by Sqreater · · Score: 2

    "...treatments are evolving faster than Watson's human trainers can update the system"

    And if you do away with the mass of humans doing a particular area of expertise and turn it over to "AI" you will freeze that area at that level of AI expertise. The AI has no motivation array. It can't look for ways to "do it better," as humans constantly do. It cannot advance the field. AI is potentially a human disaster if too much trust is given it. Remember, Watson was built, programmed, turned on to play Jeopardy by humans. Then it was turned off when it had satisfied the motivations of its creators. It did not WANT to play Jeopardy, or anything else. It is a rock, a tool. Nothing else. Unmotivated intelligence is not intelligence. We must not rely on it.

    --
    E Proelio Veritas.
  29. Watson Jeopardy != this system by bangular · · Score: 1

    Just to be clear, the system that beat Ken Jennings has very little to do with Watson in its current incarnation. Much of the team was splitup after the Jeopardy demonstration and IBM decided there wasn't much market for a question/answer system such as this.

    So they reused the name, banking on the general population having heard of Watson Jeopardy to drive sales. Watson in its current incarnation is actually mostly off-the-shelf open source and existing IBM tools. Apache Spark and IBM's SPSS are currently under the Watson umbrella.

    Watson Jeopardy was interesting for the time, but other companies are doing much more interesting things these days.